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  1. Book ; Online ; E-Book: Image-guided high-precision radiotherapy

    Troost, Esther Gera Cornelia

    2022  

    Abstract: Intro -- Preface -- Contents -- Part I: Target Volume Definition -- 1: Use of [18F]FDG PET/CT for Target Volume Definition in Radiotherapy -- 1.1 Introduction -- 1.2 [18F]FDG PET/CT -- 1.2.1 PET/CT -- 1.2.2 [18F]FDG -- 1.3 Technical Aspects -- 1.3.1 ... ...

    Author's details Esther G. C. Troost editor
    Abstract Intro -- Preface -- Contents -- Part I: Target Volume Definition -- 1: Use of [18F]FDG PET/CT for Target Volume Definition in Radiotherapy -- 1.1 Introduction -- 1.2 [18F]FDG PET/CT -- 1.2.1 PET/CT -- 1.2.2 [18F]FDG -- 1.3 Technical Aspects -- 1.3.1 Patient Preparation -- 1.3.2 Image Acquisition and Reconstruction -- 1.3.3 Fusion and Registration of Treatment Planning PET/CT -- 1.3.3.1 Registration PET with CTAC -- 1.3.3.2 Registration PET(/CT) with Planning-CT -- 1.3.4 Motion -- 1.3.4.1 Types of Motion -- 1.3.4.2 Motion Correction Methods -- Alignment -- Compensation Methods for Respiratory Motion -- 1.4 Target Volume Delineation -- 1.4.1 PET/CT in Target Volume Delineation -- 1.4.2 PET/CT Segmentation Methods -- 1.4.2.1 Manual, Semi-Automatic and Automatic Segmentation Methods -- 1.4.2.2 Drawback of Segmentation Methods -- 1.4.2.3 Consensus Algorithms -- 1.4.3 Disease Sites -- 1.4.3.1 NSCLC and SCLC -- 1.4.3.2 HNSCC -- 1.4.3.3 Oesophageal Cancer -- 1.4.3.4 Gynaecological Tumours -- 1.4.3.5 Lymphoma -- 1.4.3.6 Other Tumours -- 1.5 Cons and Pitfalls -- 1.5.1 Limited Spatial Resolution and High Signal-to-Noise Ratio of PET -- 1.5.2 Interpretation Errors Due to Limited Specificity (and Sensitivity) of the Radiopharmaceutical [18F]FDG -- 1.6 Future Outlook -- References -- 2: Specific PET Tracers for Solid Tumors and for Definition of the Biological Target Volume -- 2.1 Introduction -- 2.2 Brain Tumors -- 2.2.1 Glioma Hypoxia and Activated Microglia -- 2.2.2 Meningioma -- 2.3 Head and Neck Squamous Cell Carcinomas (HNSCC) -- 2.4 Non-small Cell Lung Cancer -- 2.5 Prostate Cancer -- 2.5.1 PET in Primary Staging -- 2.5.2 Salvage Radiotherapy in Recurrent Prostate Cancer -- 2.6 Future Prospects -- References -- 3: Use of Anatomical and Functional MRI in Radiation Treatment Planning -- 3.1 Introduction.
    Keywords Image-guided radiation therapy ; Electronic books
    Language English
    Size 1 Online-Ressource (viii, 314 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Note Description based on publisher supplied metadata and other sources
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT030021414
    ISBN 978-3-031-08601-4 ; 9783031086007 ; 3-031-08601-5 ; 3031086007
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Thesis: Der Einfluss von Strahlentherapie, systemischer Therapie und Therapiereihenfolge auf das Überleben von Patienten mit Melanomhirnmetastasen

    Bruns, Johannes / Meier, Friedegund / Troost, Esther Gera Cornelia

    2022  

    Institution Universitäts KrebsCentrum
    Author's details von Johannes Bruns aus Wernigerode ; Universitäts KrebsCentrum [Dresden]
    Language German
    Size 80 Blätter, Illustrationen, Diagramme
    Publishing place Dresden
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Technische Universität Dresden, Medizinische Fakultät, 2022
    HBZ-ID HT030629950
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Thesis: Radiomics-Analysen der 18F-FDG-PET/CT bei Patienten mit Kopf-Hals-Plattenepithelkarzinomen

    Maile, Till Robin / Troost, Esther Gera Cornelia / Zöphel, Klaus

    2021  

    Institution Klinik und Poliklinik für Strahlentherapie und Radioonkologie
    Author's details von Till Robin Maile aus Aalen ; Klinik und Poliklinik für Strahlentherapie und Radioonkologie [Dresden]
    Language German
    Size VIII, 67 Seiten, Illustrationen, Diagramme
    Publishing place Dresden
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Technische Universität Dresden, Medizinische Fakultät, 2022
    HBZ-ID HT021379344
    Database Catalogue ZB MED Medicine, Health

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  4. Book ; Thesis: Retrospektive Analyse der ausgeführten PSMA-Bildgebung bei Patienten mit high-risk Prostatakarzinom oder biochemischem Rezidiv

    Goldammer, Imke Katharina / Troost, Esther Gera Cornelia / Brogsitter, Claudia

    2021  

    Institution Klinik und Poliklinik für Strahlentherapie und Radioonkologie
    Author's details von Imke Katharina Goldammer, geb. Bachmann aus Naila ; Klinik und Poliklinik für Strahlentherapie und Radioonkologie [Dresden]
    Language German
    Size 79 Blätter, Illustrationen, Diagramme
    Publishing place Dresden
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Technische Universität Dresden, Medizinische Fakultät, 2021
    HBZ-ID HT021368851
    Database Catalogue ZB MED Medicine, Health

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  5. Book ; Thesis: Interleukin polymorphisms in Helicobacter pylori associated gastric cancer

    Troost, Esther Gera Cornelia

    = Interleukin-Polymorphismen bei Helicobacter-pylori-assoziiertem Magenkrebs

    2007  

    Title variant Interleukin-Polymorphismen bei Helicobacter-pylori-assoziiertem Magenkrebs
    Author's details vorgelegt von Esther Gera Cornelia Troost
    Subject code 616.994
    Language English
    Size 126 S., Ill., graph. Darst., 30 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Hannover, Med. Hochsch., Diss., 2008
    HBZ-ID HT015704512
    Database Catalogue ZB MED Medicine, Health

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  6. Article ; Online: Wirksamkeit und Sicherheit einer Kohlenstoffionentherapie lokal rezidivierter Rektumkarzinome: Ergebnisse der J‑CROS-Studie 1404 Rektum.

    Jentsch, Christina / Troost, Esther G C

    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al

    2019  Volume 195, Issue 8, Page(s) 769–770

    Title translation Efficacy and safety of carbon-ion radiotherapy for locally recurrent rectal cancer: results of the J‑CROS Study 1404 Rectum.
    MeSH term(s) Carbon ; Humans ; Japan ; Neoplasm Recurrence, Local ; Radiation Oncology ; Rectal Neoplasms ; Rectum
    Chemical Substances Carbon (7440-44-0)
    Language German
    Publishing date 2019-04-20
    Publishing country Germany
    Document type Journal Article ; Comment
    ZDB-ID 84983-2
    ISSN 1439-099X ; 0179-7158 ; 0039-2073
    ISSN (online) 1439-099X
    ISSN 0179-7158 ; 0039-2073
    DOI 10.1007/s00066-019-01471-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Prediction of radiation pneumonitis using the effective α/β of lungs and heart in NSCLC patients treated with proton beam therapy.

    Weiß, Albrecht / Löck, Steffen / Xu, Ting / Liao, Zhongxing / Hoffmann, Aswin L / Troost, Esther G C

    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

    2023  Volume 190, Page(s) 110013

    Abstract: Purpose: Radiation pneumonitis (RP) remains a major complication in non-small cell lung cancer (NSCLC) patients undergoing radiochemotherapy (RCHT). Traditionally, the mean lung dose (MLD) and the volume of the total lung receiving at least 20 Gy (V: ... ...

    Abstract Purpose: Radiation pneumonitis (RP) remains a major complication in non-small cell lung cancer (NSCLC) patients undergoing radiochemotherapy (RCHT). Traditionally, the mean lung dose (MLD) and the volume of the total lung receiving at least 20 Gy (V
    Methods: Data on the occurrence of RP, structure files and dose-volume histogram parameters for lungs and heart of 96 NSCLC patients, treated with PSPT and concurrent chemotherapy, was retrospectively retrieved from prospective clinical studies of two international centers. Data was randomly split into a training set (64 patients) and a validation set (32 patients). Statistical analyses were performed using binomial logistic regression.
    Results: The biologically effective dose (BED) of the'lungs - GTV' significantly predicted RP ≥ grade 2 in the training-set using both a univariate model (p = 0.019, AUC
    Conclusion: Using the effective α/β parameter of the lungs and heart we achieved similar performance to commonly used models built for photon therapy, such as MLD, in predicting RP ≥ grade 2. Therefore, prediction models developed for photon RCHT still hold for patients treated with PSPT.
    MeSH term(s) Humans ; Carcinoma, Non-Small-Cell Lung/radiotherapy ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Radiation Pneumonitis/etiology ; Proton Therapy/adverse effects ; Proton Therapy/methods ; Lung Neoplasms/radiotherapy ; Lung Neoplasms/drug therapy ; Retrospective Studies ; Prospective Studies ; Lung ; Radiotherapy Dosage
    Language English
    Publishing date 2023-11-14
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 605646-5
    ISSN 1879-0887 ; 0167-8140
    ISSN (online) 1879-0887
    ISSN 0167-8140
    DOI 10.1016/j.radonc.2023.110013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: MR Image Changes of Normal-Appearing Brain Tissue after Radiotherapy.

    Witzmann, Katharina / Raschke, Felix / Troost, Esther G C

    Cancers

    2021  Volume 13, Issue 7

    Abstract: Radiotherapy is part of the standard treatment of most primary brain tumors. Large clinical target volumes and physical characteristics of photon beams inevitably lead to irradiation of surrounding normal brain tissue. This can cause radiation-induced ... ...

    Abstract Radiotherapy is part of the standard treatment of most primary brain tumors. Large clinical target volumes and physical characteristics of photon beams inevitably lead to irradiation of surrounding normal brain tissue. This can cause radiation-induced brain injury. In particular, late brain injury, such as cognitive dysfunction, is often irreversible and progressive over time, resulting in a significant reduction in quality of life. Since 50% of patients have survival times greater than six months, radiation-induced side effects become more relevant and need to be balanced against radiation treatment given with curative intent. To develop adequate treatment and prevention strategies, the underlying cause of radiation-induced side-effects needs to be understood. This paper provides an overview of radiation-induced changes observed in normal-appearing brains measured with conventional and advanced MRI techniques and summarizes the current findings and conclusions. Brain atrophy was observed with anatomical MRI. Changes in tissue microstructure were seen on diffusion imaging. Vascular changes were examined with perfusion-weighted imaging and susceptibility-weighted imaging. MR spectroscopy revealed decreasing N-acetyl aspartate, indicating decreased neuronal health or neuronal loss. Based on these findings, multicenter prospective studies incorporating advanced MR techniques as well as neurocognitive function tests should be designed in order to gain more evidence on radiation-induced sequelae.
    Language English
    Publishing date 2021-03-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers13071573
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Proton therapy special feature: introductory editorial.

    Held, Kathryn D / Lomax, Antony J / Troost, Esther G C

    The British journal of radiology

    2020  Volume 93, Issue 1107, Page(s) 20209004

    MeSH term(s) Humans ; Neoplasms/radiotherapy ; Proton Therapy/methods
    Language English
    Publishing date 2020-02-21
    Publishing country England
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 2982-8
    ISSN 1748-880X ; 0007-1285
    ISSN (online) 1748-880X
    ISSN 0007-1285
    DOI 10.1259/bjr.20209004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Strahlentherapie beim nicht metastasierten Lungenkarzinom

    Troost, Esther G.C.

    TumorDiagnostik & Therapie

    2018  Volume 39, Issue 06, Page(s) 362–366

    Language German
    Publishing date 2018-07-31
    Publisher © Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2072365-9
    ISSN 1439-1279 ; 0722-219X
    ISSN (online) 1439-1279
    ISSN 0722-219X
    DOI 10.1055/a-0604-4661
    Database Thieme publisher's database

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