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  1. Book ; Thesis: Mechanische und metabolische Phänotypisierung peripherer Immunzellen als mögliche zellbasierte Biomarker in der Charakterisierung von Multiple Sklerose Patienten

    Demitrowitz, Nadja / Ziemssen, Tjalf / Bornstein, Stefan R.

    2021  

    Institution Klinik und Poliklinik für Neurologie
    Author's details von Nadja Demitrowitz aus Berlin ; Klinik und Poliklinik für Neurologie [Dresden]
    Language German
    Size LXI, 94 Seiten, Illustrationen, Diagramme
    Publishing place Dresden
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Technische Universität Dresden, Medizinische Fakultät, 2021
    HBZ-ID HT021367868
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Thesis: A single cell map of the developing endoderm implicates fxr in hepatopancreatic development

    Kamel, Margrit / Guan, Kaomei / Bornstein, Stefan R.

    2021  

    Institution Center for Regenerative Therapies Dresden
    Author's details von Margrit Kamel
    Language English
    Size iv, 84 Seiten, Illustrationen, Diagramme
    Publishing place Dresden
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Technische Universität Dresden, Medizinische Fakultät, 2021
    HBZ-ID HT021249984
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Thesis: Characterisation of Adrenal Cells in Metabolic Disease

    Scriba, Laura Donata / Bornstein, Stefan R. / Guan, Kaomei

    2021  

    Institution Medizinische Klinik und Poliklinik III
    Author's details von Laura Donata Scriba aus München ; Medizinische Klinik und Poliklinik III [Dresden]
    Language English
    Size 79 Seiten, Illustrationen, Diagramme
    Publishing place Dresden
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Technische Universität Dresden, Medizinische Fakultät, 2022
    HBZ-ID HT021714769
    Database Catalogue ZB MED Medicine, Health

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  4. Book: Depression and type 2 diabetes

    Ismail, Khalida / Barthel, Andreas / Bornstein, Stefan R.

    2018  

    Author's details edited by Khalida Ismail, Andreas Barthel, Stefan R. Bornstein, Julio Licinio
    Language English
    Size xvi, 250 Seiten, Illustrationen
    Publisher Oxford University Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT019842656
    ISBN 978-0-19-878928-4 ; 0-19-878928-9
    Database Catalogue ZB MED Medicine, Health

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  5. Book: Evolution, stress and moderne medicine

    Bornstein, Stefan R.

    2006  

    Author's details by Stefan R. Bornstein
    Keywords Evolution ; Umwelt ; Stress
    Subject Nervöse Belastung ; Physischer Stress ; Psychischer Stress ; Stresssituation ; Abstammung
    Language English
    Size 124 S. : Ill., 21 cm
    Publisher Progressmedia
    Publishing place Dresden
    Publishing country Germany
    Document type Book
    Note Literaturverz. S. 98 - 123
    HBZ-ID HT015350707
    ISBN 978-3-00-018765-0 ; 3-00-018765-0
    Database Catalogue ZB MED Medicine, Health

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  6. Article ; Online: International Roadshow: New Advances in Endocrinology and Metabolic Diseases.

    Steenblock, Charlotte / Saber-Ayad, Maha M / Bornstein, Stefan R

    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme

    2024  Volume 56, Issue 4, Page(s) 259–260

    Abstract: Dear Readers,Currently, there is a myriad of new developments in the field of endocrinology. In particular, significant strides have been made in the development of poly-agonists for the treatment of type 2 diabetes and obesity 1 2. Poly-agonists ... ...

    Abstract Dear Readers,Currently, there is a myriad of new developments in the field of endocrinology. In particular, significant strides have been made in the development of poly-agonists for the treatment of type 2 diabetes and obesity 1 2. Poly-agonists represent a novel therapeutic approach by combining multiple actions within a single molecule, targeting multiple receptors simultaneously to achieve enhanced efficacy. These innovative compounds aim to address the complex interplay of hormonal pathways involved in glucose regulation and metabolism, offering potential breakthroughs in the management of diabetes and obesity.
    MeSH term(s) Humans ; Diabetes Mellitus, Type 2/drug therapy ; Metabolic Diseases/therapy ; Glucose/metabolism ; Endocrinology ; Obesity/drug therapy
    Chemical Substances Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2024-04-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 80125-2
    ISSN 1439-4286 ; 0018-5043
    ISSN (online) 1439-4286
    ISSN 0018-5043
    DOI 10.1055/a-2256-7180
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Patient-reported outcome measures after metabolic surgery.

    Mingrone, Geltrude / Castagneto-Gissey, Lidia / Bornstein, Stefan R

    The lancet. Diabetes & endocrinology

    2023  Volume 11, Issue 8, Page(s) 527–529

    MeSH term(s) Humans ; Patient Reported Outcome Measures ; Bariatric Surgery ; Treatment Outcome
    Language English
    Publishing date 2023-07-03
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2213-8595
    ISSN (online) 2213-8595
    DOI 10.1016/S2213-8587(23)00173-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Artificial intelligence in diabetes mellitus and endocrine diseases - what can we expect?

    Oikonomakos, Ioannis T / Steenblock, Charlotte / Bornstein, Stefan R

    Nature reviews. Endocrinology

    2023  Volume 19, Issue 7, Page(s) 375–376

    MeSH term(s) Humans ; Artificial Intelligence ; Diabetes Mellitus/diagnosis ; Diabetes Mellitus/epidemiology
    Language English
    Publishing date 2023-05-24
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2489381-X
    ISSN 1759-5037 ; 1759-5029
    ISSN (online) 1759-5037
    ISSN 1759-5029
    DOI 10.1038/s41574-023-00852-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Sensitivity of the Neuroendocrine Stress Axis in Metabolic Diseases.

    Cozma, Diana / Siatra, Panagiota / Bornstein, Stefan R / Steenblock, Charlotte

    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme

    2024  Volume 56, Issue 1, Page(s) 65–77

    Abstract: Metabolic diseases are prevalent in modern society and have reached pandemic proportions. Metabolic diseases have systemic effects on the body and can lead to changes in the neuroendocrine stress axis, the critical regulator of the body's stress response. ...

    Abstract Metabolic diseases are prevalent in modern society and have reached pandemic proportions. Metabolic diseases have systemic effects on the body and can lead to changes in the neuroendocrine stress axis, the critical regulator of the body's stress response. These changes may be attributed to rising insulin levels and the release of adipokines and inflammatory cytokines by adipose tissue, which affect hormone production by the neuroendocrine stress axis. Chronic stress due to inflammation may exacerbate these effects. The increased sensitivity of the neuroendocrine stress axis may be responsible for the development of metabolic syndrome, providing a possible explanation for the high prevalence of severe comorbidities such as heart disease and stroke associated with metabolic disease. In this review, we address current knowledge of the neuroendocrine stress axis in response to metabolic disease and discuss its role in developing metabolic syndrome.
    MeSH term(s) Humans ; Metabolic Syndrome/metabolism ; Adipokines ; Cytokines ; Inflammation/complications
    Chemical Substances Adipokines ; Cytokines
    Language English
    Publishing date 2024-01-03
    Publishing country Germany
    Document type Review ; Journal Article
    ZDB-ID 80125-2
    ISSN 1439-4286 ; 0018-5043
    ISSN (online) 1439-4286
    ISSN 0018-5043
    DOI 10.1055/a-2201-6641
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Sex-based differences in insulin resistance.

    Gado, Manuel / Tsaousidou, Eva / Bornstein, Stefan R / Perakakis, Nikolaos

    The Journal of endocrinology

    2024  Volume 261, Issue 1

    Abstract: Sexual dimorphism in energy metabolism is now established and suggested to affect many aspects of metabolic diseases and in particular diabetes and obesity. This is strongly related to sex-based differences in whole-body insulin resistance. Women are ... ...

    Abstract Sexual dimorphism in energy metabolism is now established and suggested to affect many aspects of metabolic diseases and in particular diabetes and obesity. This is strongly related to sex-based differences in whole-body insulin resistance. Women are more insulin sensitive compared to men, but this metabolic advantage gradually disappears after menopause or when insulin resistance progresses to hyperglycemia and diabetes. In this narrative review, first, we describe the pathophysiology related to insulin resistance and then we present the epidemiological evidence as well as the important biological factors that play a crucial role in sexual dimorphism in insulin sensitivity. We focus particularly on the differences in body fat and muscle mass distribution and function, in inflammation and in sex hormones between males and females. Most importantly, we describe the significant mechanistic differences in insulin sensitivity as well as glucose and lipid metabolism in key metabolic organs: liver, white adipose tissue, and skeletal muscle. Finally, we present the sex-based differences in response to different interventions and discuss important open research questions.
    MeSH term(s) Male ; Humans ; Female ; Insulin Resistance/physiology ; Sex Characteristics ; Obesity/metabolism ; Insulin/metabolism ; Adipose Tissue/metabolism ; Diabetes Mellitus/metabolism ; Muscle, Skeletal/metabolism
    Chemical Substances Insulin
    Language English
    Publishing date 2024-02-12
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 3028-4
    ISSN 1479-6805 ; 0022-0795
    ISSN (online) 1479-6805
    ISSN 0022-0795
    DOI 10.1530/JOE-23-0245
    Database MEDical Literature Analysis and Retrieval System OnLINE

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