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  1. Article ; Online: Domestic sources of ‘mild’ positions on international cooperation

    Federica Genovese

    Italian Political Science, Vol 15, Iss

    Italy and global climate policy

    2020  Volume 1

    Abstract: This paper investigates Italy's position on global climate change politics in order to explore the larger question of why this country, like similar middle powers, may adopt ambiguous positions on global public policy issues. I start from the observation ...

    Abstract This paper investigates Italy's position on global climate change politics in order to explore the larger question of why this country, like similar middle powers, may adopt ambiguous positions on global public policy issues. I start from the observation that in recent history Italy has taken a rather mild posi-tion on international climate cooperation and climate policy more broadly. To explain this, I propose an argument in divergence with those who claim Italy has low salience in the issue or lack of interest in international climate leadership. I put forward a political economy perspective and claim that different salient concerns motivate the domestic actors that shape the country’s international position. I main-tain that these different concerns offset each other, resulting in overall mild preferences. I present support for my theory, zooming in on the motivations of two domestic sources of international posi-tions: economic sectors and public opinion. The empirical data largely corroborates the theory.
    Keywords italy ; international cooperation ; climate change ; political economy ; domestic politics ; Political science (General) ; JA1-92 ; Political theory ; JC11-607
    Subject code 300
    Language English
    Publishing date 2020-05-01T00:00:00Z
    Publisher Università degli Studi di Catania
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: Quantifying peripheral modulation of olfaction by trigeminal agonists.

    Federica, Genovese / Jiang, Xu / Marco, Tizzano / Johannes, Reisert

    bioRxiv : the preprint server for biology

    2023  

    Abstract: In the mammalian nose, two chemosensory systems, the trigeminal and the olfactory mediate the detection of volatile chemicals. Most odorants in fact are able to activate the trigeminal system, and vice versa, most trigeminal agonists activate the ... ...

    Abstract In the mammalian nose, two chemosensory systems, the trigeminal and the olfactory mediate the detection of volatile chemicals. Most odorants in fact are able to activate the trigeminal system, and vice versa, most trigeminal agonists activate the olfactory system as well. Although these two systems constitute two separate sensory modalities, trigeminal activation modulates the neural representation of an odor. The mechanisms behind the modulation of olfactory response by trigeminal activation are still poorly understood. In this study, we addressed this question by looking at the olfactory epithelium, where olfactory sensory neurons and trigeminal sensory fibers co-localize and where the olfactory signal is generated. We characterize the trigeminal activation in response to five different odorants by measuring intracellular Ca
    Language English
    Publishing date 2023-03-14
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.03.13.532477
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Quantifying Peripheral Modulation of Olfaction by Trigeminal Agonists.

    Genovese, Federica / Xu, Jiang / Tizzano, Marco / Reisert, Johannes

    The Journal of neuroscience : the official journal of the Society for Neuroscience

    2023  Volume 43, Issue 47, Page(s) 7958–7966

    Abstract: In the mammalian nose, two chemosensory systems, the trigeminal and the olfactory mediate the detection of volatile chemicals. Most odorants are able to activate the trigeminal system, and vice versa, most trigeminal agonists activate the olfactory ... ...

    Abstract In the mammalian nose, two chemosensory systems, the trigeminal and the olfactory mediate the detection of volatile chemicals. Most odorants are able to activate the trigeminal system, and vice versa, most trigeminal agonists activate the olfactory system as well. Although these two systems constitute two separate sensory modalities, trigeminal activation modulates the neural representation of an odor. The mechanisms behind the modulation of olfactory response by trigeminal activation are still poorly understood. We addressed this question by looking at the olfactory epithelium (OE), where olfactory sensory neurons (OSNs) and trigeminal sensory fibers co-localize and where the olfactory signal is generated. Our study was conducted in a mouse model. Both sexes, males and females, were included. We characterize the trigeminal activation in response to five different odorants by measuring intracellular Ca
    MeSH term(s) Male ; Humans ; Female ; Mice ; Animals ; Smell/physiology ; Olfactory Receptor Neurons/physiology ; Olfactory Mucosa ; Odorants ; Mice, Knockout ; Phenylethyl Alcohol/pharmacology ; Mammals
    Chemical Substances Phenylethyl Alcohol (ML9LGA7468)
    Language English
    Publishing date 2023-11-22
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 604637-x
    ISSN 1529-2401 ; 0270-6474
    ISSN (online) 1529-2401
    ISSN 0270-6474
    DOI 10.1523/JNEUROSCI.0489-23.2023
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    Zs.A 1668: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  4. Article ; Online: The role of fibrosis in cardiomyopathies: An opportunity to develop novel biomarkers of disease activity.

    Angeli, Elisavet / Jordan, Maria / Otto, Mandy / Stojanović, Stevan D / Karsdal, Morten / Bauersachs, Johann / Thum, Thomas / Fiedler, Jan / Genovese, Federica

    Matrix biology : journal of the International Society for Matrix Biology

    2024  Volume 128, Page(s) 65–78

    Abstract: Cardiomyopathies encompass a spectrum of heart disorders with diverse causes and presentations. Fibrosis stands out as a shared hallmark among various cardiomyopathies, reflecting a common thread in their pathogenesis. This prevalent fibrotic response is ...

    Abstract Cardiomyopathies encompass a spectrum of heart disorders with diverse causes and presentations. Fibrosis stands out as a shared hallmark among various cardiomyopathies, reflecting a common thread in their pathogenesis. This prevalent fibrotic response is intricately linked to the consequences of dysregulated extracellular matrix (ECM) remodeling, emphasizing its significance in the development and progression the disease. This review explores the ECM involvement in various cardiomyopathies and its impact on myocardial stiffness and fibrosis. Additionally, we discuss the potential of ECM fragments as early diagnosis, prognosis, and risk stratification. Biomarkers deriving from turnover of collagens and other ECM proteins hold promise in clinical applications. We outline current clinical management, future directions, and the potential for personalized ECM-targeted therapies with specific focus on microRNAs. In summary, this review examines the role of the fibrosis in cardiomyopathies, highlighting the potential of ECM-derived biomarkers in improving disease management with implications for precision medicine.
    MeSH term(s) Humans ; Fibrosis ; Extracellular Matrix/metabolism ; Cardiomyopathies/diagnosis ; Cardiomyopathies/genetics ; Cardiomyopathies/metabolism ; Extracellular Matrix Proteins/metabolism ; Biomarkers/metabolism
    Chemical Substances Extracellular Matrix Proteins ; Biomarkers
    Language English
    Publishing date 2024-02-28
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1183793-7
    ISSN 1569-1802 ; 0945-053X
    ISSN (online) 1569-1802
    ISSN 0945-053X
    DOI 10.1016/j.matbio.2024.02.008
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    Zs.A 1694: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  5. Article ; Online: Local businesses' consumption and perception of Single-Use Plastics: A preliminary assessment for conservation and mitigation plans in the Egadi Islands Marine Protected Area

    Genovese, Martina / Mangano, Maria Cristina / Papa, Federica / Romeo, Teresa / Greco, Silvestro

    Marine Pollution Bulletin. 2023 Sept., v. 194 p.115252-

    2023  

    Abstract: Modern society depends on plastic, especially through single-use plastic products (SUPs), which can affect ecological systems after use. Local policymakers can strategically adopt measures against SUPs pollution by setting effective local governance. ... ...

    Abstract Modern society depends on plastic, especially through single-use plastic products (SUPs), which can affect ecological systems after use. Local policymakers can strategically adopt measures against SUPs pollution by setting effective local governance. This work was designed to evaluate SUPs consumption inside the Marine Protected Area of the Egadi Islands. A questionnaire mixed approach to understanding stakeholders' consumption, attitudes and perceptions about the uses and impacts of SUPs in the third sector was used. Results show a significant seasonal consumption of SUPs and uncertainty in the behaviour to discard them. These provide valuable insights to fill research gaps in estimating the use of SUPs and consumers' perceptions. The main aim of this work has been to understand the critical issues regarding the use of SUPs, considering the target area's patterns, in support of designing action plans for changing behaviour and the mitigation of critical issues in favour of environmental conservation.
    Keywords governance ; marine pollution ; marine protected areas ; questionnaires ; stakeholders ; uncertainty ; SUP ; Policymaking ; MPA ; Conservation ; Social perception ; Waste management
    Language English
    Dates of publication 2023-09
    Publishing place Elsevier Ltd
    Document type Article ; Online
    ZDB-ID 2001296-2
    ISSN 1879-3363 ; 0025-326X
    ISSN (online) 1879-3363
    ISSN 0025-326X
    DOI 10.1016/j.marpolbul.2023.115252
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: Local businesses' consumption and perception of Single-Use Plastics: A preliminary assessment for conservation and mitigation plans in the Egadi Islands Marine Protected Area.

    Genovese, Martina / Mangano, Maria Cristina / Papa, Federica / Romeo, Teresa / Greco, Silvestro

    Marine pollution bulletin

    2023  Volume 194, Issue Pt A, Page(s) 115252

    Abstract: Modern society depends on plastic, especially through single-use plastic products (SUPs), which can affect ecological systems after use. Local policymakers can strategically adopt measures against SUPs pollution by setting effective local governance. ... ...

    Abstract Modern society depends on plastic, especially through single-use plastic products (SUPs), which can affect ecological systems after use. Local policymakers can strategically adopt measures against SUPs pollution by setting effective local governance. This work was designed to evaluate SUPs consumption inside the Marine Protected Area of the Egadi Islands. A questionnaire mixed approach to understanding stakeholders' consumption, attitudes and perceptions about the uses and impacts of SUPs in the third sector was used. Results show a significant seasonal consumption of SUPs and uncertainty in the behaviour to discard them. These provide valuable insights to fill research gaps in estimating the use of SUPs and consumers' perceptions. The main aim of this work has been to understand the critical issues regarding the use of SUPs, considering the target area's patterns, in support of designing action plans for changing behaviour and the mitigation of critical issues in favour of environmental conservation.
    MeSH term(s) Plastics ; Islands ; Environmental Pollution ; Commerce ; Perception
    Chemical Substances Plastics
    Language English
    Publishing date 2023-07-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2001296-2
    ISSN 1879-3363 ; 0025-326X
    ISSN (online) 1879-3363
    ISSN 0025-326X
    DOI 10.1016/j.marpolbul.2023.115252
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  7. Article ; Online: [No title information]

    Federica Genovese

    Research & Politics, Vol

    Religious authority and the Pope in modern international relations

    2015  Volume 2

    Abstract: Political scientists are increasingly interested in the impact of religious authority on modern politics. However, little attention has been paid to the conditions under which religious leaders are more likely to speak politically. Tackling this question, ...

    Abstract Political scientists are increasingly interested in the impact of religious authority on modern politics. However, little attention has been paid to the conditions under which religious leaders are more likely to speak politically. Tackling this question, this article argues that religious authorities should issue political statements at the outbreak of international crises, when secular institutions are unwilling or incapable of taking clear political positions. I test this argument focusing on the Roman Vatican through a quantitative text analysis of the papal encyclicals from 1958 until today. Latent topic models indicate that political themes systematically emerge in the papal documents and that the timing of the more political encyclicals correlate with years in which international crises break out. The findings have implications for the understanding of the modern relations between state and church and the political mobilization of religion today.
    Keywords Political science ; J
    Language English
    Publishing date 2015-10-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Sensory Transduction in Photoreceptors and Olfactory Sensory Neurons: Common Features and Distinct Characteristics.

    Genovese, Federica / Reisert, Johannes / Kefalov, Vladimir J

    Frontiers in cellular neuroscience

    2021  Volume 15, Page(s) 761416

    Abstract: The past decades have seen tremendous progress in our understanding of the function of photoreceptors and olfactory sensory neurons, uncovering the mechanisms that determine their properties and, ultimately, our ability to see and smell. This progress ... ...

    Abstract The past decades have seen tremendous progress in our understanding of the function of photoreceptors and olfactory sensory neurons, uncovering the mechanisms that determine their properties and, ultimately, our ability to see and smell. This progress has been driven to a large degree by the powerful combination of physiological experimental tools and genetic manipulations, which has enabled us to identify the main molecular players in the transduction cascades of these sensory neurons, how their properties affect the detection and discrimination of stimuli, and how diseases affect our senses of vision and smell. This review summarizes some of the common and unique features of photoreceptors and olfactory sensory neurons that make these cells so exciting to study.
    Language English
    Publishing date 2021-10-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2452963-1
    ISSN 1662-5102
    ISSN 1662-5102
    DOI 10.3389/fncel.2021.761416
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  9. Article ; Online: A survey to evaluate knowledge, attitudes, and practices associated with the risk of foodborne infection in a sample of Sicilian general population.

    Amodio, Emanuele / Calamusa, Giuseppe / Tiralongo, Salvatore / Lombardo, Federica / Genovese, Dario

    AIMS public health

    2022  Volume 9, Issue 3, Page(s) 458–470

    Abstract: Although foodborne infections contracted at home are frequent diseases worldwide, there is a general lack of information. Main purpose of this cross-sectional study was to evaluate knowledge, attitudes, and practices (KAP) of a sample of the general ... ...

    Abstract Although foodborne infections contracted at home are frequent diseases worldwide, there is a general lack of information. Main purpose of this cross-sectional study was to evaluate knowledge, attitudes, and practices (KAP) of a sample of the general Sicilian population about the risk of contracting foodborne diseases. It was carried out through a web-based questionnaire to a Sicilian population sample. The questionnaire collected socio-demographic data, health issues, KAP and self-reported diseases. Scores were calculated for summarizing the results. A total of 373 subjects participated into the study. Overall, 65.15% of the participants were females, 48.26% of all respondents were aged between 18 and 29 years and over one-third were students (34.58%). At least one episode of vomiting/diarrhoea in the previous 3 months was reported by 119 respondents. Practices were associated with knowledge (R
    Language English
    Publishing date 2022-05-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2777115-5
    ISSN 2327-8994 ; 2327-8994
    ISSN (online) 2327-8994
    ISSN 2327-8994
    DOI 10.3934/publichealth.2022031
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  10. Article ; Online: Effects of the administration of Elovl5-dependent fatty acids on a spino-cerebellar ataxia 38 mouse model.

    Balbo, Ilaria / Montarolo, Francesca / Genovese, Federica / Tempia, Filippo / Hoxha, Eriola

    Behavioral and brain functions : BBF

    2022  Volume 18, Issue 1, Page(s) 8

    Abstract: Background: Spinocerebellar ataxia 38 (SCA38) is a rare autosomal neurological disorder characterized by ataxia and cerebellar atrophy. SCA38 is caused by mutations of ELOVL5 gene. ELOVL5 gene encodes a protein, which elongates long chain ... ...

    Abstract Background: Spinocerebellar ataxia 38 (SCA38) is a rare autosomal neurological disorder characterized by ataxia and cerebellar atrophy. SCA38 is caused by mutations of ELOVL5 gene. ELOVL5 gene encodes a protein, which elongates long chain polyunsaturated fatty acids (PUFAs). Knockout mice lacking Elovl5 recapitulate SCA38 symptoms, including motor coordination impairment and disruption of cerebellar architecture. We asked whether, in Elovl5 knockout mice (Elovl5
    Results: The administration from birth of the diet containing PUFAs downstream Elovl5 led to a significant amelioration of the motor performance in the beam test of Elovl5
    Conclusions: These results suggest that the dietary intervention in SCA38, whenever possible, should be started from birth or as early as possible.
    MeSH term(s) Animals ; Cerebellum ; Disease Models, Animal ; Fatty Acid Elongases/metabolism ; Fatty Acids/administration & dosage ; Fatty Acids, Unsaturated ; Mice ; Mice, Knockout ; Spinocerebellar Ataxias/diet therapy
    Chemical Substances Fatty Acids ; Fatty Acids, Unsaturated ; Elovl5 protein, mouse (EC 2.3.1.-) ; Fatty Acid Elongases (EC 2.3.1.-)
    Language English
    Publishing date 2022-08-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185773-8
    ISSN 1744-9081 ; 1744-9081
    ISSN (online) 1744-9081
    ISSN 1744-9081
    DOI 10.1186/s12993-022-00194-4
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