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  1. Article ; Online: A review of zeta potential measurements using electroacoustics.

    Mohammadi-Jam, Shiva / Waters, Kristian E / Greenwood, Richard W

    Advances in colloid and interface science

    2022  Volume 309, Page(s) 102778

    Abstract: The electroacoustic technique has been successfully used to determine the zeta potential of concentrated aqueous suspensions for over thirty years. This article reviews its use in mineral processing, ceramics, zeolites, and other industrial minerals and ... ...

    Abstract The electroacoustic technique has been successfully used to determine the zeta potential of concentrated aqueous suspensions for over thirty years. This article reviews its use in mineral processing, ceramics, zeolites, and other industrial minerals and in particular identifies the isoelectric points of these materials, as this parameter is crucial for determining colloidal stability and hence subsequent processing. Some benefits of this technique over the traditional electrokinetic measurement techniques are also highlighted. Finally, the application of the technique to polymer lattices is summarized.
    MeSH term(s) Suspensions ; Zeolites ; Water ; Polymers
    Chemical Substances Suspensions ; Zeolites (1318-02-1) ; Water (059QF0KO0R) ; Polymers
    Language English
    Publishing date 2022-09-27
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 210507-x
    ISSN 1873-3727 ; 0001-8686
    ISSN (online) 1873-3727
    ISSN 0001-8686
    DOI 10.1016/j.cis.2022.102778
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Simple, accurate calculation of mechanical power in pressure controlled ventilation (PCV).

    Trinkle, Christine A / Broaddus, Richard N / Sturgill, Jamie L / Waters, Christopher M / Morris, Peter E

    Intensive care medicine experimental

    2022  Volume 10, Issue 1, Page(s) 22

    Abstract: Background: Mechanical power is a promising new metric to assess energy transfer from a mechanical ventilator to a patient, which combines the contributions of multiple parameters into a single comprehensive value. However, at present, most ventilators ... ...

    Abstract Background: Mechanical power is a promising new metric to assess energy transfer from a mechanical ventilator to a patient, which combines the contributions of multiple parameters into a single comprehensive value. However, at present, most ventilators are not capable of calculating mechanical power automatically, so there is a need for a simple equation that can be used to estimate this parameter at the bedside. For volume-controlled ventilation (VCV), excellent equations exist for calculating power from basic ventilator parameters, but for pressure-controlled ventilation (PCV), an accurate, easy-to-use equation has been elusive.
    Results: Here, we present a new power equation and evaluate its accuracy compared to the three published PCV power equations. When applied to a sample of 50 patients on PCV with a non-zero rise time, we found that our equation estimated power within an average of 8.4% ± 5.9% (mean ± standard deviation) of the value obtained by numerical integration of the P-V loop. The other three equations estimated power with an error of 19.4% ± 12.9% (simplified Becher equation), 10.0% ± 6.8% (comprehensive Becher equation), and 16.5% ± 14.6% (van der Meijden equation).
    Conclusions: Our equation calculates power more accurately than the other three published equations, and is much easier to use than the only previously published equation with similar accuracy. The proposed new mechanical power equation is accurate and simple to use, making it an attractive option to estimate power in PCV cases at the bedside.
    Language English
    Publishing date 2022-05-30
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2740385-3
    ISSN 2197-425X
    ISSN 2197-425X
    DOI 10.1186/s40635-022-00448-5
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  3. Article ; Online: No overall impact on rate of weight gain with integrase inhibitor-containing regimens in antiretroviral-naïve adults.

    Burns, James E / Stirrup, Oliver / Waters, Laura / Dunn, David / Gilson, Richard / Pett, Sarah L

    HIV medicine

    2021  Volume 23, Issue 3, Page(s) 294–300

    Abstract: Objectives: Integrase strand transfer inhibitors (INSTIs) are commonplace in modern antiretroviral therapy (ART). Increased weight gain with their use is increasingly scrutinized. We evaluated weight changes in treatment-naïve adults with HIV-1 ... ...

    Abstract Objectives: Integrase strand transfer inhibitors (INSTIs) are commonplace in modern antiretroviral therapy (ART). Increased weight gain with their use is increasingly scrutinized. We evaluated weight changes in treatment-naïve adults with HIV-1 attending a UK centre who started regimens including raltegravir or dolutegravir.
    Methods: A retrospective cohort study of adults prescribed an INSTI between January 2015 and March 2020 were categorized as having started an ART regimen containing raltegravir, dolutegravir, a protease inhibitor or a nonnucleoside reverse transcriptase inhibitor. Individuals with one or more weight measurement ≤ 5 years both pre- and post-ART initiation, who started a three-drug regimen with ≥ 6 months duration and achieved virological suppression (< 50 copies/mL) within 6 months were included. A random effects model with linear slope pre- and post-ART was used, adjusting for age, gender, ethnicity, ART regimen, backbone and year of initiation.
    Results: The cohort included 390 adults; 88.7% were male, 66.4% were of white ethnicity, their median age was 40 years, there was a median of six weight measurements, 2.2 years from diagnosis to ART initiation, 2.9 years from ART to the last weight measurement, and weight and body mass index at initiation were 75 kg and 24.1 kg/m
    Conclusions: Weight increased in the cohort both pre- and post-ART. We found no evidence of a higher rate of weight gain following ART initiation with an INSTI compared with other regimens.
    MeSH term(s) Adult ; HIV Infections/drug therapy ; HIV Integrase Inhibitors/adverse effects ; Humans ; Male ; Retrospective Studies ; Reverse Transcriptase Inhibitors/adverse effects ; Weight Gain
    Chemical Substances HIV Integrase Inhibitors ; Reverse Transcriptase Inhibitors
    Language English
    Publishing date 2021-10-11
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2001932-4
    ISSN 1468-1293 ; 1464-2662
    ISSN (online) 1468-1293
    ISSN 1464-2662
    DOI 10.1111/hiv.13186
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Fear-potentiated startle predicts longitudinal change in transdiagnostic symptom dimensions of anxiety and depression.

    Yarrington, Julia S / Vinograd, Meghan / Williams, Alexander L / Wolitzky-Taylor, Kate B / Zinbarg, Richard E / Mineka, Susan / Waters, Allison M / Craske, Michelle G

    Journal of affective disorders

    2022  Volume 311, Page(s) 399–406

    Abstract: ... to predict longitudinal change in three symptom factors (i.e., General Distress, Fears, Anhedonia ...

    Abstract Background: Elevated defensive responding, through startle reflex (SR) and skin conductance response (SCR), may contribute to onset and maintenance of depression and anxiety. Most work examining SR and SCR has predicted psychiatric diagnoses. There is a paucity of research examining links between SR or SCR and dimensional measures of psychopathology.
    Methods: We used latent growth curve modeling to predict longitudinal change in three symptom factors (i.e., General Distress, Fears, Anhedonia-Apprehension) from SR and SCR measured during a fear-potentiated startle paradigm among adolescents oversampled for neuroticism (N = 129).
    Results: Elevated SCR in danger phases before and after an unpleasant muscle contraction predicted increasing Fears over time. Elevated SR in safe phases post-contraction also predicted increasing Fears over time. Attenuated SR in safe phases post-contraction predicted elevated General Distress longitudinally. Attenuated SCR pre-contraction in danger phases predicted elevated Anhedonia-Apprehension over time.
    Limitations: Our non-clinical sample may limit generalizability of results. Additionally, we did not assess change in SR and SCR over time.
    Conclusions: The present study demonstrates that SR and SCR during a fear-potentiated startle paradigm predict longitudinal change in dimensional anxiety and depression symptom factors and relatedly, that SR and SCR may represent risk factors for the exacerbation of symptomatology.
    MeSH term(s) Adolescent ; Anhedonia ; Anxiety/diagnosis ; Anxiety/psychology ; Anxiety Disorders/psychology ; Depression/diagnosis ; Fear/psychology ; Humans ; Reflex, Startle
    Language English
    Publishing date 2022-05-19
    Publishing country Netherlands
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, N.I.H., Extramural
    ZDB-ID 135449-8
    ISSN 1573-2517 ; 0165-0327
    ISSN (online) 1573-2517
    ISSN 0165-0327
    DOI 10.1016/j.jad.2022.05.080
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  5. Article ; Online: Fish biogeography and hybridization: do contemporary distributions predict introgression history?

    Waters, Jonathan M / Campbell, Ciaran S M / Dutoit, Ludovic

    Evolution; international journal of organic evolution

    2023  Volume 77, Issue 11, Page(s) 2409–2419

    Abstract: ... of introgression among taxa that currently have disjunct distributions within drainages (e.g., separate ... rich freshwater Galaxias vulgaris fish complex. Genome-wide comparisons reveal significant increases ...

    Abstract Freshwater ecosystems frequently house diverse assemblages of closely related fish taxa, which can be particularly prone to hybridization and introgression. While extensive introgression may be expected among biogeographically proximate lineages, recent analyses imply that contemporary distributions do not always accurately predict hybridization history. Here, we use the ABBA-BABA approach to test biogeographic hypotheses regarding the extent of hybridization in the recent evolution of New Zealand's species-rich freshwater Galaxias vulgaris fish complex. Genome-wide comparisons reveal significant increases in introgression associated with increasing geographic overlap of taxa. The estimator DP, which assesses the net proportion of a genome originating from introgression, shows a particularly strong relationship with biogeographic overlap (R2 = .43; p = .005). Our analyses nevertheless reveal surprisingly substantial signatures of introgression among taxa that currently have disjunct distributions within drainages (e.g., separate subcatchments). These "anomalies" imply that current biogeography is not always an accurate predictor of introgression history. Our study suggests that both modern and ancient biogeographic shifts, including recent anthropogenic range fragmentation and tectonically driven riven capture events, have influenced introgression histories in this dynamic freshwater fish radiation.
    MeSH term(s) Animals ; Ecosystem ; Fishes/genetics ; Hybridization, Genetic ; Genome ; Nucleic Acid Hybridization ; Phylogeny
    Language English
    Publishing date 2023-08-16
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2036375-8
    ISSN 1558-5646 ; 0014-3820
    ISSN (online) 1558-5646
    ISSN 0014-3820
    DOI 10.1093/evolut/qpad147
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Clinical and radiological septic joint analysis of spontaneous sternoclavicular joint infections: achieving the best outcomes-a systems engineering approach.

    Pothini, Tanushri / Wilmot, Charles D / Waters, John K / Wait, Michael A / Reznik, Scott I / Jordan, Kirk G / Caire, Jacqueline T / Ashworth, John M / Cady, Leah C / Lysikowski, Jerzy R / Yen, Christina F / Weinschenk, Robert C / Samade, Richard / Jessen, Michael E / Kusiak, Andrew / Kernstine, Kemp H

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2024  Volume 65, Issue 4

    Abstract: Objectives: Spontaneous sternoclavicular joint infection (SSCJI) is a rare and poorly understood disease process. This study aims to identify factors guiding effective management strategies for SSCJI by using data mining.: Methods: An Institutional ... ...

    Abstract Objectives: Spontaneous sternoclavicular joint infection (SSCJI) is a rare and poorly understood disease process. This study aims to identify factors guiding effective management strategies for SSCJI by using data mining.
    Methods: An Institutional Review Board-approved retrospective review of patients from 2 large hospitals (2010-2022) was conducted. SSCJI is defined as a joint infection without direct trauma or radiation, direct instrumentation or contiguous spread. An interdisciplinary team consisting of thoracic surgeons, radiologists, infectious disease specialists, orthopaedic surgeons, hospital information experts and systems engineers selected relevant variables. Small set data mining algorithms, utilizing systems engineering, were employed to assess the impact of variables on patient outcomes.
    Results: A total of 73 variables were chosen and 54 analysed against 11 different outcomes. Forty-seven patients [mean age 51 (22-82); 77% male] met criteria. Among them, 34 underwent early joint surgical resection (<14 days), 5 patients received delayed surgical intervention (>14 days) and 8 had antibiotic-only management. The antibiotic-only group had comparable outcomes. Indicators of poor outcomes were soft tissue fluid >4.5 cm, previous SSCJI, moderate/significant bony fragments, HgbA1c >13.9% and moderate/significant bony sclerosis.
    Conclusions: This study suggests that targeted antibiotic-only therapy should be considered initially for SSCJI cases while concurrently managing comorbidities. Patients displaying indicators of poor outcomes or no symptomatic improvement after antibiotic-only therapy should be considered for surgical joint resection.
    MeSH term(s) Humans ; Male ; Middle Aged ; Female ; Sternoclavicular Joint/diagnostic imaging ; Sternoclavicular Joint/surgery ; Arthritis, Infectious/drug therapy ; Arthritis, Infectious/surgery ; Retrospective Studies ; Tomography, X-Ray Computed ; Anti-Bacterial Agents/therapeutic use
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2024-03-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezae128
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  7. Article ; Online: Reporting the results of a clinical trial across multiple papers, does it matter?

    Gray, Richard / Mackay, Bridgina / Waters, Amanda / Brown, Ellie

    European journal of cardiovascular nursing

    2021  Volume 20, Issue 6, Page(s) 618–619

    Language English
    Publishing date 2021-07-13
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2151245-0
    ISSN 1873-1953 ; 1474-5151
    ISSN (online) 1873-1953
    ISSN 1474-5151
    DOI 10.1093/eurjcn/zvaa010
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  8. Article ; Online: The influence of physical activity in water on sleep quality in pregnant women: A case study in salami slicing?

    Gray, Richard / Mackay, Bridgina / Waters, Amanda / Brown, Ellie

    Women and birth : journal of the Australian College of Midwives

    2021  Volume 34, Issue 3, Page(s) e330–e331

    MeSH term(s) Exercise ; Female ; Humans ; Pregnancy ; Pregnant Women ; Publishing ; Sleep ; Water
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2021-04-07
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2235085-8
    ISSN 1878-1799 ; 1871-5192
    ISSN (online) 1878-1799
    ISSN 1871-5192
    DOI 10.1016/j.wombi.2020.12.010
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  9. Article ; Online: HIV and overdoses: diversifying therapies for opioid use disorder.

    Waters, Richard C / Oviedo-Joekes, Eugenia / Rawlins, Jesse

    Lancet (London, England)

    2021  Volume 398, Issue 10302, Page(s) 741–742

    MeSH term(s) Drug Overdose/epidemiology ; HIV Infections/drug therapy ; HIV Infections/epidemiology ; Humans ; Opioid-Related Disorders/epidemiology ; Opioid-Related Disorders/therapy
    Language English
    Publishing date 2021-08-28
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(21)01251-4
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  10. Article ; Online: The Motivational Determinants of Human Action, Their Neural Bases and Functional Impact in Adolescents With Obsessive-Compulsive Disorder.

    Perkes, Iain E / Morris, Richard W / Griffiths, Kristi R / Quail, Stephanie / Waters, Felicity / O'Brien, Margot / Hazell, Philip L / Balleine, Bernard W

    Biological psychiatry global open science

    2022  Volume 3, Issue 4, Page(s) 1062–1072

    Abstract: Background: Establishing the motivational influences on human action is essential for understanding choice and decision making in health and disease. Here we used tests of value-based decision making, manipulating both predicted and experienced reward ... ...

    Abstract Background: Establishing the motivational influences on human action is essential for understanding choice and decision making in health and disease. Here we used tests of value-based decision making, manipulating both predicted and experienced reward values to assess the motivational control of goal-directed action in healthy adolescents and those with obsessive-compulsive disorder (OCD).
    Methods: After instrumental training on a two action-two outcome probabilistic task, adolescents (
    Results: In healthy adolescents, both predicted and experienced values influenced the performance of goal-directed actions, mediated by distinct orbitofrontal-striatal circuits involving the lateral orbitofrontal cortex (OFC) and medial OFC, respectively. However, in adolescents with OCD, choice was insensitive to changes in either predicted or experienced values. These impairments were related to hypoactivity in the lateral OFC and hyperactivity in the medial OFC during specific Pavlovian-instrumental transfer and hypoactivity in the anterior prefrontal cortex, caudate nucleus, and their connectivity in the devaluation test.
    Conclusions: We found that predicted and experienced values exerted a potent influence on the performance of goal-directed actions in adolescents via distinct orbitofrontal- and prefrontal-striatal circuits. Furthermore, the influence of these motivational processes was severely blunted in OCD, as was the functional segregation of circuits involving medial and lateral OFC, producing dysregulated action control.
    Language English
    Publishing date 2022-12-05
    Publishing country United States
    Document type Journal Article
    ISSN 2667-1743
    ISSN (online) 2667-1743
    DOI 10.1016/j.bpsgos.2022.11.004
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