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  1. Article ; Online: Identifying poorer asthma control using oscillometry ratios.

    Chan, Rory / Lipworth, Brian

    The journal of allergy and clinical immunology. In practice

    2023  Volume 12, Issue 2, Page(s) 506–508.e1

    MeSH term(s) Humans ; Oscillometry ; Asthma/diagnosis ; Asthma/epidemiology ; Spirometry
    Language English
    Publishing date 2023-11-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2023.10.048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Oral corticosteroid prescribing practice for chronic rhinosinusitis with nasal polyps among otorhinolaryngologists in Scotland: a nationwide survey.

    Misirovs, Rasads / Hoey, Gary / Lipworth, Brian / Green, Richard

    The Journal of laryngology and otology

    2024  , Page(s) 1–18

    Language English
    Publishing date 2024-04-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 218299-3
    ISSN 1748-5460 ; 0022-2151
    ISSN (online) 1748-5460
    ISSN 0022-2151
    DOI 10.1017/S0022215124000446
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Characterizing patients with moderate-to-severe asthma with preserved small airway function.

    Chan, Rory / Lipworth, Brian

    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

    2023  Volume 132, Issue 1, Page(s) 93–95

    MeSH term(s) Humans ; Asthma ; Respiratory System
    Language English
    Publishing date 2023-10-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1228189-x
    ISSN 1534-4436 ; 0003-4738 ; 1081-1206
    ISSN (online) 1534-4436
    ISSN 0003-4738 ; 1081-1206
    DOI 10.1016/j.anai.2023.10.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Have we reached our final destination with biologics in severe uncontrolled asthma?

    Lipworth, Brian / Chan, Rory

    The journal of allergy and clinical immunology. In practice

    2023  Volume 11, Issue 5, Page(s) 1575–1576

    MeSH term(s) Humans ; Biological Products/therapeutic use ; Asthma/drug therapy ; Anti-Asthmatic Agents/therapeutic use
    Chemical Substances Biological Products ; Anti-Asthmatic Agents
    Language English
    Publishing date 2023-05-06
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2023.02.029
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  5. Article ; Online: The triple type 2 signature confers more frequent exacerbations and worse midexpiratory flow in moderate to severe asthma.

    Chan, Rory / Lipworth, Brian

    The journal of allergy and clinical immunology. In practice

    2023  Volume 11, Issue 9, Page(s) 2926–2928.e1

    MeSH term(s) Humans ; Asthma
    Language English
    Publishing date 2023-05-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2023.05.021
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  6. Article ; Online: Domiciliary assessment of the type 2 inflammatory FeNO type.

    Lipworth, Brian / Chan, Rory

    The journal of allergy and clinical immunology. In practice

    2023  Volume 11, Issue 6, Page(s) 1981

    MeSH term(s) Humans ; Asthma/diagnosis ; Nitric Oxide ; Breath Tests ; Exhalation ; Biomarkers
    Chemical Substances Nitric Oxide (31C4KY9ESH) ; Biomarkers
    Language English
    Publishing date 2023-06-08
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2023.02.038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Real-life effects of dupilumab on airway oscillometry in severe uncontrolled asthma.

    Chan, Rory / Lipworth, Brian

    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

    2023  Volume 131, Issue 5, Page(s) 664–666

    MeSH term(s) Humans ; Oscillometry ; Asthma/drug therapy ; Antibodies, Monoclonal, Humanized/therapeutic use
    Chemical Substances dupilumab (420K487FSG) ; Antibodies, Monoclonal, Humanized
    Language English
    Publishing date 2023-07-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1228189-x
    ISSN 1534-4436 ; 0003-4738 ; 1081-1206
    ISSN (online) 1534-4436
    ISSN 0003-4738 ; 1081-1206
    DOI 10.1016/j.anai.2023.07.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Disconnect for Tezepelumab on Exacerbations, Symptoms, and Quality of Life in Type 2 Low Asthma.

    Lipworth, Brian / Chan, Rory

    American journal of respiratory and critical care medicine

    2023  Volume 208, Issue 2, Page(s) 211

    MeSH term(s) Humans ; Quality of Life ; Asthma/drug therapy ; Asthma/diagnosis ; Antibodies, Monoclonal, Humanized/therapeutic use ; Anti-Asthmatic Agents/therapeutic use
    Chemical Substances tezepelumab (RJ1IW3B4QX) ; Antibodies, Monoclonal, Humanized ; Anti-Asthmatic Agents
    Language English
    Publishing date 2023-06-06
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202304-0746LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Efficacy of biologic therapy on airway hyperresponsiveness in asthma.

    Chan, Rory / Lipworth, Brian

    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

    2023  Volume 131, Issue 1, Page(s) 37–41

    Abstract: Airway hyperresponsiveness refers to an exaggerated bronchial constrictor response to a given exogenous inhaled agent and is governed by airway smooth muscle along with mucosal inflammation in asthma. In recent years, the advent of biologics and ... ...

    Abstract Airway hyperresponsiveness refers to an exaggerated bronchial constrictor response to a given exogenous inhaled agent and is governed by airway smooth muscle along with mucosal inflammation in asthma. In recent years, the advent of biologics and antialarmins has transformed severe asthma treatment in terms of reducing oral-corticosteroid-requiring exacerbations and improving disease control, asthma quality of life, and spirometry-measured lung function. In contrast, there have been comparatively fewer studies investigating the efficacy of biologics in airway hyperresponsiveness. In this focused review, we summarize the existing evidence base in this area regarding omalizumab, mepolizumab, benralizumab, and tezepelumab.
    MeSH term(s) Humans ; Anti-Asthmatic Agents/therapeutic use ; Quality of Life ; Asthma ; Omalizumab/therapeutic use ; Biological Therapy ; Biological Products/therapeutic use
    Chemical Substances Anti-Asthmatic Agents ; Omalizumab (2P471X1Z11) ; Biological Products
    Language English
    Publishing date 2023-02-23
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1228189-x
    ISSN 1534-4436 ; 0003-4738 ; 1081-1206
    ISSN (online) 1534-4436
    ISSN 0003-4738 ; 1081-1206
    DOI 10.1016/j.anai.2023.02.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Clinical impact of obesity on oscillometry lung mechanics in adults with asthma.

    Chan, Rory / Lipworth, Brian

    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

    2023  Volume 131, Issue 3, Page(s) 338–342.e3

    Abstract: Background: In the year 2035, projections have estimated that 5% of the Scottish population will be morbidly obese defined as a body mass index (BMI) greater than or equal to 40 kg/m: Objective: To evaluate the impact of obesity on lung mechanics ... ...

    Abstract Background: In the year 2035, projections have estimated that 5% of the Scottish population will be morbidly obese defined as a body mass index (BMI) greater than or equal to 40 kg/m
    Objective: To evaluate the impact of obesity on lung mechanics using oscillometry.
    Methods: Clinical data for 188 patients with respiratory physician-diagnosed moderate-to-severe asthma were retrospectively collected and analyzed.
    Results: Obesity (BMI 30-39.9 kg/m
    Conclusion: Obesity is associated with worse peripheral airway dysfunction in moderate-to-severe asthma, including a patient cluster who was older, obese, and female with more frequent exacerbations.
    MeSH term(s) Humans ; Adult ; Female ; Obesity, Morbid/complications ; Retrospective Studies ; Oscillometry ; Asthma ; Lung ; Spirometry
    Language English
    Publishing date 2023-05-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1228189-x
    ISSN 1534-4436 ; 0003-4738 ; 1081-1206
    ISSN (online) 1534-4436
    ISSN 0003-4738 ; 1081-1206
    DOI 10.1016/j.anai.2023.05.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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