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  1. Article ; Online: Mavrilimumab for severe COVID-19.

    Pourhoseingholi, Mohamad Amin / Shojaee, Sajad / Ashtari, Sara

    The Lancet Rheumatology

    2020  Volume 2, Issue 11, Page(s) e662

    Language English
    Publishing date 2020-09-05
    Publishing country England
    Document type Journal Article
    ISSN 2665-9913
    ISSN (online) 2665-9913
    DOI 10.1016/S2665-9913(20)30307-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Three potential challenges in studying COVID-19 pandemic data: Chinese statistics, social media, and preprint servers.

    Pourhoseingholi, Mohamad Amin / Shojaee, Sajad / Ashtari, Sara

    Gastroenterology and hepatology from bed to bench

    2020  Volume 13, Issue 4, Page(s) 278–279

    Language English
    Publishing date 2020-11-27
    Publishing country Iran
    Document type Editorial
    ZDB-ID 2569124-7
    ISSN 2008-4234 ; 2008-2258
    ISSN (online) 2008-4234
    ISSN 2008-2258
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Mavrilimumab for severe COVID-19

    Pourhoseingholi, Mohamad Amin / Shojaee, Sajad / Ashtari, Sara

    The Lancet Rheumatology

    2020  Volume 2, Issue 11, Page(s) e662

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2665-9913
    DOI 10.1016/s2665-9913(20)30307-6
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: A systematic review and meta-analysis for the association of the insulin-like growth factor1 pathway genetic polymorphisms with colorectal cancer susceptibility.

    Cheraghpour, Makan / Askari, Masomeh / Tierling, Sascha / Shojaee, Sajad / Sadeghi, Amir / Ketabi Moghadam, Pardis / Khazdouz, Maryam / Asadzadeh Aghdaei, Hamid / Piroozkhah, Moein / Nazemalhosseini-Mojarad, Ehsan / Fatemi, Nayeralsadat

    Frontiers in oncology

    2023  Volume 13, Page(s) 1168942

    Abstract: Background: The receptors, ligands, and associated proteins of the insulin-like growth factor (IGF) family are involved in cancer development. The : Methods: We performed a comprehensive search strategy in PubMed, Scopus, and Web of Science databases ...

    Abstract Background: The receptors, ligands, and associated proteins of the insulin-like growth factor (IGF) family are involved in cancer development. The
    Methods: We performed a comprehensive search strategy in PubMed, Scopus, and Web of Science databases for articles available until Aug 30, 2022. A total of 26 eligible studies with
    Results: The meta-analysis of available data for rs6214C>T, rs1801278G>A, and rs1805097G>A showed a significant association between these polymorphisms and an increased CRC risk in some of the comparisons studied (rs6214C>T, pooled OR for CC = 0.43, 95% CI 0.21- 0.87, P = 0.019; rs1801278G>A, OR for GA = 0.74, 95% CI 0.58-0.94, P = 0.016; rs1805097G>A, OR for GA = 0.83, 95% CI 0.71-0.96, P = 0.013). Nevertheless, the meta-analysis did not include other genetic variations in
    Conclusions: This systematic review and meta-analysis provide evidence that genetic variants in
    Language English
    Publishing date 2023-05-22
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1168942
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Overview of epidemiological characteristics, clinical features, and risk factors of gastric cancer in Asia-Pacific region.

    Akbari, Abolfazl / Ashtari, Sara / Tabaiean, Seidamir Pasha / Mehrdad-Majd, Hassan / Farsi, Farnaz / Shojaee, Sajad / Agah, Shahram

    Asia-Pacific journal of clinical oncology

    2022  Volume 18, Issue 6, Page(s) 493–505

    Abstract: In spite of decreasing the overall incidence of gastric cancer (GC), it remains one of the most common and deadly cancers worldwide. The incidence and mortality rate of GC is very different in the world. Geographical differentiation is one of the most ... ...

    Abstract In spite of decreasing the overall incidence of gastric cancer (GC), it remains one of the most common and deadly cancers worldwide. The incidence and mortality rate of GC is very different in the world. Geographical differentiation is one of the most distinctive characteristics of GC. Effective prevention and early diagnostic strategies are the most important public health interventions in GC, as a common malignancy worldwide. Notably, the preventive strategies require understanding the risk factors associated with GC for identifying high-risk groups that may require screening for prevention. Therefore, up-to-date statistics on GC occurrence and outcome are essential for the primary prevention of the disease. We conducted this review based on the current epidemiology knowledge of GC to provide an update perspective of GC in Asia-Pacific region. Based on the findings of this study, incidence and mortality rate of GC in Asia-Pacific region shows a great heterogeneity. Gastric carcinogenesis arises as a consequence of a complex interaction between host and environmental factors. In addition to screening and eradication of Helicobacter pylori (H. pylori) infection, it seems that the main cause of GC is an undesirable lifestyle in this region. Therefore, it is necessary to improve the lifestyle and the community awareness about GC risk factors and healthy lifestyle education.
    MeSH term(s) Humans ; Stomach Neoplasms/diagnosis ; Stomach Neoplasms/epidemiology ; Stomach Neoplasms/prevention & control ; Helicobacter pylori ; Helicobacter Infections/complications ; Helicobacter Infections/epidemiology ; Helicobacter Infections/diagnosis ; Risk Factors ; Asia/epidemiology
    Language English
    Publishing date 2022-01-24
    Publishing country Australia
    Document type Journal Article ; Review
    ZDB-ID 2187409-8
    ISSN 1743-7563 ; 1743-7555
    ISSN (online) 1743-7563
    ISSN 1743-7555
    DOI 10.1111/ajco.13654
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: How much does vaccination reduce the rate of HBV infection in Iranian population? a Bayesian adjustment analysis.

    Shojaee, Sajad / Zayeri, Farid / Nasserinejad, Maryam / Ghasemzadeh, Ali / Sadat Beheshti Shirazi, Saeedeh / Khodadoostan, Mahsa

    Gastroenterology and hepatology from bed to bench

    2020  Volume 12, Issue Suppl1, Page(s) S136–S144

    Abstract: Aim: The aim of this research was to estimate the changing rate of odds ratio (OR) by varying degrees of hepatitis B virus (HBV) underreporting.: Background: Data registering is usually associated with extensive errors such as misclassification, ... ...

    Abstract Aim: The aim of this research was to estimate the changing rate of odds ratio (OR) by varying degrees of hepatitis B virus (HBV) underreporting.
    Background: Data registering is usually associated with extensive errors such as misclassification, under-reporting, missing data due to lack of co-operation, error prone factors, and in medical studies, inadequate diagnosis of physicians or low accuracy of laboratory tests. In the present study, which discuss the actual impact of vaccination on HBV prevention, exposure and response were prone to various errors. Furthermore, some people in the community are possibly infected to the virus while were not reported in the count of patients with HBV infection.
    Methods: This was a case control study. Cases included patients with HBV referring to the gastroenterology and liver disease research center. The control group included patients without HBV who underwent a fatty liver test at Taleghani hospital laboratory. Bayesian approach and Gibbs sampling algorithm were used to estimate OR.
    Results: According to results, misclassification rate was mild in raw data, but with an increase in degree of underreporting for 50 and 500 of unreported cases, OR increased by about half and more than double, respectively, while sensitivity diminished strikingly.
    Conclusion: Our analysis asserted that knowing the degree of underreporting is essential to accurately calculate OR and sensitivity. In addition, despite varying OR in different samples, overall the results were similar according to the pattern of exposure and response association.
    Language English
    Publishing date 2020-02-17
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2569124-7
    ISSN 2008-4234 ; 2008-2258
    ISSN (online) 2008-4234
    ISSN 2008-2258
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Predicting the mortality due to Covid-19 by the next month for Italy, Iran and South Korea; a simulation study.

    Shojaee, Sajad / Pourhoseingholi, Mohamad Amin / Ashtari, Sara / Vahedian-Azimi, Amir / Asadzadeh-Aghdaei, Hamid / Zali, Mohammad Reza

    Gastroenterology and hepatology from bed to bench

    2020  Volume 13, Issue 2, Page(s) 177–179

    Abstract: Aim: To estimate the number of confirmed cases and the rate of death and also to investigate the cause of death in Italy, Iran and South Korea in the next month.: Background: Growing number of confirmed and deaths cases from the coronavirus worldwide, ...

    Abstract Aim: To estimate the number of confirmed cases and the rate of death and also to investigate the cause of death in Italy, Iran and South Korea in the next month.
    Background: Growing number of confirmed and deaths cases from the coronavirus worldwide, particularly in Italy, Iran and South Korea, has resulted concerns about the future of these countries and their deterioration. Also the European region is likely to face more casualties due to the delay in the virus reaching most of its regions and, of course, as the trend continues.
    Methods: We conducted a simulation in both current and ideal situation for the next month to predict the death rate and examine the reason for the difference in Italy, Iran and South Korea individually. If we assume the cultural and political factors and age pyramids distribution are similar across regions, the differences are mainly due either to the heavier health-care burden owing to the larger population or to the medical facilities diversities.
    Results: Our results for Italy showed higher death number, but the rate would be more for Iran. South Korea is also expected to have a smaller increase in the number of confirmed cases and deaths compared to Iran and Italy by the next month.
    Conclusion: Given the prevailing conditions around the world and the increasing number of casualties, it is essential that all countries, especially those with fewer days of involvement, shall do their best to avoid major losses and damages.
    Keywords covid19
    Language English
    Publishing date 2020-03-23
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2569124-7
    ISSN 2008-4234 ; 2008-2258
    ISSN (online) 2008-4234
    ISSN 2008-2258
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A cluster analysis of epidemiological and clinical factors associated with the accumulation process of the burden of COVID-19 in European countries.

    Shojaee, Sajad / Eslami, Pegah / Dooghaie Moghadam, Arash / Pourhoseingholi, Mohamad Amin / Ashtari, Sara / Vahedian-Azimi, Amir / Zali, Mohammad Reza

    Acta bio-medica : Atenei Parmensis

    2020  Volume 92, Issue 1, Page(s) e2021022

    Abstract: Background and aim of the work European COVID-19 statistics showed differentiation between mortality and new cases. Some studies suggested several factors including migration, cancer incidence, life expectancy and health system capacity maybe associated ... ...

    Abstract Background and aim of the work European COVID-19 statistics showed differentiation between mortality and new cases. Some studies suggested several factors including migration, cancer incidence, life expectancy and health system capacity maybe associated with differentiations. Up to now, impact of those factors in different European societies is not discussed and compared. Aim of the present study was to perform the cluster analysis in European countries in attention to clinical and epidemiological factors due to covid-19. Methods We collected some appropriate extreme data of COVID-19 to access the situations by ANOVA post-hoc test in 3 scenarios, as well as to estimate regression coefficients in simple linear regression, and a cluster analysis using average linkage. Covid-19 Statistics were considered in all analyses until April 24, 2020. Results Among 39 European countries, several countries reported highest rate of confirmed cases included of Italy (current statues=2270.52) and Spain (current status=2616.24). The highest rate of mortality was seen in France (current status=242.16), Italy (current status=305.52). Life expectancy (female) (P=0.01, 95%Cl=1521.27,15264.58), migration (P<0.001, 95%Cl=41.42,96.72) had significant association with confirmed cases and death. Overall cancer death (P<0.001, 95%Cl=0.36,0.68; P<0.001, 95%Cl=0.01,0.07) and lung cancer death (P<0.001, 95%Cl=1.97,3.56; P<0.001, 95%Cl=0.09,0.37) associated with confirmed cases and mortality, too. We were also determined 5 clusters which more than 30 countries were categorized in the first cluster. Conclusions Demographic factors, including population, life expectancy and migration, underlying disorders, such as several types of cancers, especially lung cancers lead to various distribution of COVID-19 in terms of prevalence and mortality, across European counties.
    MeSH term(s) COVID-19/epidemiology ; COVID-19/mortality ; Cluster Analysis ; Emigration and Immigration ; Europe/epidemiology ; Humans ; Life Expectancy ; SARS-CoV-2
    Language English
    Publishing date 2020-11-10
    Publishing country Italy
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2114240-3
    ISSN 2531-6745 ; 0392-4203
    ISSN (online) 2531-6745
    ISSN 0392-4203
    DOI 10.23750/abm.v92i1.10090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: COVID-19 and ICU admission associated predictive factors in Iranian patients.

    Sadeghi, Amir / Eslami, Pegah / Dooghaie Moghadam, Arash / Pirsalehi, Ali / Shojaee, Sajad / Vahidi, Mohammad / Soheili, Amirali / Ghanimat, Faezeh / Keshmiri, Yasaman / Abdi, Saeed / Zali, Mohammad Reza

    Caspian journal of internal medicine

    2021  Volume 11, Issue Suppl 1, Page(s) 512–519

    Abstract: Background: The pandemic situation created an overwhelmed needs for ICU facilities, according to this problem, the need of accurate management of facilities represents boldness. In this study, prognostic risk factors for ICU admission among COVID-19 ... ...

    Abstract Background: The pandemic situation created an overwhelmed needs for ICU facilities, according to this problem, the need of accurate management of facilities represents boldness. In this study, prognostic risk factors for ICU admission among COVID-19 hospitalized patients were evaluated.
    Methods: From 22 February to April 20, 2020. A total of 214 COVID-19 patients participated in this study. The included patients were between 18- 80 years old, and the patients who previously admitted for COVID-19 were excluded. The comorbid medical conditions, admission laboratory, demographic data, and first manifestations were analyzed between two groups, including ICU and non-ICU admitted patients. The statistical analysis, univariate and multivariate analysis were afforded. The value of the predictors in the risk assessment of ICU admission was estimated.
    Results: 55(25.7%) patients were admitted in ICU. The ICU admitted patient's mortality rate was about 68%. The age was significantly higher among ICU admission group (P=0.03). Admission O2 saturation was significantly lower among ICU admitted patients (P=0.00). The kidney disease and malignancy history were more frequent in ICU-admitted patients (P=0.04, P=0.00). Myalgia was the clinical manifestation that significantly presented more frequent in ICU-admitted patients. INR, CRP, ESR, HB, and lymphocyte were significantly different between two groups. After multivariable analysis, admission O2 saturation, hematocrit, CRP and myalgia could significantly predict the risk of ICU admission. Furthermore, the value of predictors was estimated in our study.
    Conclusion: Based on our results, the admission O2 saturation, HCT, CRP levels at first admission and myalgia presentation could be considered as the valuable predictors of ICU admission.
    Language English
    Publishing date 2021-01-01
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2971933-1
    ISSN 2008-6172 ; 2008-6164
    ISSN (online) 2008-6172
    ISSN 2008-6164
    DOI 10.22088/cjim.11.0.512
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Bayesian adjustment for trend of colorectal cancer incidence in misclassified registering across Iranian provinces.

    Shojaee, Sajad / Hajizadeh, Nastaran / Najafimehr, Hadis / Busani, Luca / Pourhoseingholi, Mohamad Amin / Baghestani, Ahmad Reza / Nasserinejad, Maryam / Ashtari, Sara / Zali, Mohammad Reza

    PloS one

    2018  Volume 13, Issue 12, Page(s) e0199273

    Abstract: Misclassification error is a common problem of cancer registries in developing countries that leads to biased cancer rates. The purpose of this research is to use Bayesian method for correcting misclassification in registered cancer incidence of eighteen ...

    Abstract Misclassification error is a common problem of cancer registries in developing countries that leads to biased cancer rates. The purpose of this research is to use Bayesian method for correcting misclassification in registered cancer incidence of eighteen provinces in Iran. Incidence data of patients with colorectal cancer were extracted from Iranian annual of national cancer registration reports from 2005 to 2008. A province with proper medical facilities can always be compared to its neighbors. Almost 28% of the misclassification was estimated between the province of East Azarbaijan and West Azarbaijan, 56% between Fars and Hormozgan, 43% between Isfahan and Charmahal and Bakhtyari, 46% between Isfahan and Lorestan, 58% between Razavi Khorasan and North Khorasan, 50% between Razavi Khorasan and South Khorasan, 74% between Razavi Khorasan and Sistan and Balochestan, 43% between Mazandaran and Golestan, 37% between Tehran and Qazvin, 45% between Tehran and Markazi, 42% between Tehran and Qom, 47% between Tehran and Zanjan. Correcting the regional misclassification and obtaining the correct rates of cancer incidence in different regions is necessary for making cancer control and prevention programs and in healthcare resource allocation.
    MeSH term(s) Adolescent ; Adult ; Aged ; Bayes Theorem ; Child ; Child, Preschool ; Colorectal Neoplasms/epidemiology ; Female ; Humans ; Incidence ; Infant ; Infant, Newborn ; Iran/epidemiology ; Male ; Middle Aged ; Models, Biological ; Registries
    Language English
    Publishing date 2018-12-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0199273
    Database MEDical Literature Analysis and Retrieval System OnLINE

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