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Article ; Online: Letter to the Editor from Martin-Grace and Crowley: "Myxedema Heart and Pseudotamponade".

Martin-Grace, Julie / Crowley, Rachel K

Journal of the Endocrine Society

2021 Volume 5, Issue 5, Page(s) bvab026

Language	English
Publishing date	2021-03-02
Publishing country	United States
Document type	Journal Article
ISSN	2472-1972
ISSN (online)	2472-1972
DOI	10.1210/jendso/bvab026
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Article ; Online: Antarctic Ice Mass Change Products from GRACE/GRACE-FO Using Tailored Sensitivity Kernels

Andreas Groh / Martin Horwath

Remote Sensing, Vol 13, Iss 1736, p

2021 Volume 1736

Abstract: ... Climate Experiment (GRACE) mission and its successor GRACE-FO, covering more than 18 years. For this purpose ... products from GRACE/GRACE-FO Level-2 spherical harmonic solutions covering 2002-04 to 2020-07 ...

Abstract	We derived gravimetric mass change products, i.e., gridded and basin-averaged mass changes, for the Antarctic Ice Sheet (AIS) from time-variable gravity-field solutions acquired by the Gravity Recovery and Climate Experiment (GRACE) mission and its successor GRACE-FO, covering more than 18 years. For this purpose, tailored sensitivity kernels (TSKs) were generated for the application in a regional integration approach. The TSKs were inferred in a formal optimization approach minimizing the sum of both propagated mission errors and leakage errors. We accounted for mission errors by means of an empirical error covariance model, while assumptions on signal variances of potential sources of leakage were used to minimize leakage errors. To identify the optimal parameters to be used in the TSK generation, we assessed a set of TSKs by quantifying signal leakage from the processing of synthetic data and by inferring the noise level of the derived basin products. The finally selected TSKs were used to calculate mass change products from GRACE/GRACE-FO Level-2 spherical harmonic solutions covering 2002-04 to 2020-07. These products were compared to external data sets from satellite altimetry and the input–output method. For the period under investigation, the mass balance of the AIS was quantified to be <math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>−</mo><mn>90</mn><mo>.</mo><mn>9</mn><mo>±</mo><mn>43</mn><mo>.</mo><mn>5</mn></mrow></semantics></math> Gt a <math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msup><mrow></mrow><mrow><mo>−</mo><mn>1</mn></mrow></msup></semantics></math> , corresponding to a mean sea-level rise of <math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mn>0</mn><mo>.</mo><mn>25</mn><mo>±</mo><mn>0</mn><mo>.</mo><mn>12</mn></mrow></semantics></math> mm a <math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msup><mrow></mrow><mrow><mo>−</mo><mn>1</mn></mrow></msup></semantics></math> .
Keywords	Antarctic Ice Sheet ; mass change ; GRACE/GRACE-FO ; sensitivity kernels ; Science ; Q
Subject code	550
Language	English
Publishing date	2021-04-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article: Antarctic Ice Mass Change Products from GRACE/GRACE-FO Using Tailored Sensitivity Kernels

Groh, Andreas / Horwath, Martin

Remote Sensing. 2021 Apr. 29, v. 13, no. 9

2021

Abstract	We derived gravimetric mass change products, i.e., gridded and basin-averaged mass changes, for the Antarctic Ice Sheet (AIS) from time-variable gravity-field solutions acquired by the Gravity Recovery and Climate Experiment (GRACE) mission and its successor GRACE-FO, covering more than 18 years. For this purpose, tailored sensitivity kernels (TSKs) were generated for the application in a regional integration approach. The TSKs were inferred in a formal optimization approach minimizing the sum of both propagated mission errors and leakage errors. We accounted for mission errors by means of an empirical error covariance model, while assumptions on signal variances of potential sources of leakage were used to minimize leakage errors. To identify the optimal parameters to be used in the TSK generation, we assessed a set of TSKs by quantifying signal leakage from the processing of synthetic data and by inferring the noise level of the derived basin products. The finally selected TSKs were used to calculate mass change products from GRACE/GRACE-FO Level-2 spherical harmonic solutions covering 2002-04 to 2020-07. These products were compared to external data sets from satellite altimetry and the input–output method. For the period under investigation, the mass balance of the AIS was quantified to be −90.9±43.5 Gt a−1, corresponding to a mean sea-level rise of 0.25±0.12 mm a−1.
Keywords	basins ; climate ; covariance ; ice ; models ; satellite altimetry ; sea level ; Antarctic region
Language	English
Dates of publication	2021-0429
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	2513863-7
ISSN	2072-4292
ISSN	2072-4292
DOI	10.3390/rs13091736
Database	NAL-Catalogue (AGRICOLA)

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Article: States of grace

Crowther, Catherine / Schmidt, Martin

Journal of Analytical Psychology

Eureka moments and the recognition of the unthought known

2015 Volume 60, Issue 1, Page(s) 54–74

Abstract: Discusses states of grace in analysis. These encompass a range of phenomena which share ... and his understanding of the gift of grace are particularly illuminating here. The authors also ... consider the conditions which allow grace to be experienced, and how these inform analytic practice. ...

Title translation	Zustände der Gnade: Heureka-Momente und das Erkennen des ungedachten Wissens
Abstract	Discusses states of grace in analysis. These encompass a range of phenomena which share an experience of something being received or revealed rather than produced by the ego. It feels that they are events that happen rather than events that are made to occur. They are marked by a profound sense of transformation of feeling tone. The quality of relatedness in the analytic dyad is also heightened. Some of these phenomena have been referred to as experiences of the self, synchronicities, moments of meeting, the unthought known and eureka moments. The latter are experiences of sudden realization where a meaningful thought or image emerges which results in a dramatic shift in direction of the analysis and a transcendence of impasse. Although many authors describe these phenomena, it is argued that a Jungian approach provides a loom on which these threads can be woven together. Jung's concept of the transcendent function and his understanding of the gift of grace are particularly illuminating here. The authors also consider the conditions which allow grace to be experienced, and how these inform analytic practice.
Keywords	Analytical Psychotherapy ; Analytische Psychotherapie (C. G. Jung) ; Comprehension ; Einsichtsvermögen ; Emotionen ; Emotions ; Insight ; Jung (Carl) ; Psychoanalysis ; Psychoanalytische Therapie ; Psychotherapeutic Processes ; Psychotherapeutische Prozesse ; Selbstkonzept ; Selbstwahrnehmung ; Self-Concept ; Self-Perception ; Verständnis
Language	English
Document type	Article
ZDB-ID	219156-8
ISSN	1468-5922 ; 0021-8774
ISSN (online)	1468-5922
ISSN	0021-8774
DOI	10.1111/1468-5922.12129
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Article ; Online: Performance of the GRACE 2.0 score in patients with type 1 and type 2 myocardial infarction.

Hung, John / Roos, Andreas / Kadesjö, Erik / McAllister, David A / Kimenai, Dorien M / Shah, Anoop S V / Anand, Atul / Strachan, Fiona E / Fox, Keith A A / Mills, Nicholas L / Chapman, Andrew R / Holzmann, Martin J

European heart journal

2020 Volume 42, Issue 26, Page(s) 2552–2561

Abstract: Aims: The Global Registry of Acute Coronary Events (GRACE) score was developed to evaluate risk ... we calculated the GRACE 2.0 score to estimate death at 1 year. Discrimination was evaluated by the area under ... for the GRACE 2.0 score of 0.83 [95% confidence interval (CI) 0.82-0.85] and 0.85 (95% CI 0.81-0.89). Type 2 ...

Abstract	Aims: The Global Registry of Acute Coronary Events (GRACE) score was developed to evaluate risk in patients with myocardial infarction. However, its performance in type 2 myocardial infarction is uncertain. Methods and results: In two cohorts of consecutive patients with suspected acute coronary syndrome from 10 hospitals in Scotland (n = 48 282) and a tertiary care hospital in Sweden (n = 22 589), we calculated the GRACE 2.0 score to estimate death at 1 year. Discrimination was evaluated by the area under the receiver operating curve (AUC), and compared for those with an adjudicated diagnosis of type 1 and type 2 myocardial infarction using DeLong's test. Type 1 myocardial infarction was diagnosed in 4981 (10%) and 1080 (5%) patients in Scotland and Sweden, respectively. At 1 year, 720 (15%) and 112 (10%) patients died with an AUC for the GRACE 2.0 score of 0.83 [95% confidence interval (CI) 0.82-0.85] and 0.85 (95% CI 0.81-0.89). Type 2 myocardial infarction occurred in 1121 (2%) and 247 (1%) patients in Scotland and Sweden, respectively, with 258 (23%) and 57 (23%) deaths at 1 year. The AUC was 0.73 (95% CI 0.70-0.77) and 0.73 (95% CI 0.66-0.81) in type 2 myocardial infarction, which was lower than for type 1 myocardial infarction in both cohorts (P < 0.001 and P = 0.008, respectively). Conclusion: The GRACE 2.0 score provided good discrimination for all-cause death at 1 year in patients with type 1 myocardial infarction, and moderate discrimination for those with type 2 myocardial infarction. Trial registration: ClinicalTrials.gov number, NCT01852123.
MeSH term(s)	Acute Coronary Syndrome ; Anterior Wall Myocardial Infarction ; Humans ; Myocardial Infarction/epidemiology ; Prognosis ; Registries ; Risk Assessment ; Risk Factors
Language	English
Publishing date	2020-06-04
Publishing country	England
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	603098-1
ISSN	1522-9645 ; 0195-668X
ISSN (online)	1522-9645
ISSN	0195-668X
DOI	10.1093/eurheartj/ehaa375
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Article ; Online: Frailty assessment and risk prediction by GRACE score in older patients with acute myocardial infarction.

Anand, Atul / Cudmore, Sarah / Robertson, Shirley / Stephen, Jacqueline / Haga, Kristin / Weir, Christopher J / Murray, Scott A / Boyd, Kirsty / Gunn, Julian / Iqbal, Javaid / MacLullich, Alasdair / Shenkin, Susan D / Fox, Keith A A / Mills, Nicholas / Denvir, Martin A

BMC geriatrics

2020 Volume 20, Issue 1, Page(s) 102

Abstract: ... The Global Registry of Acute Coronary Events (GRACE) model includes clinical parameters and age, but not ... frailty. We hypothesised that frailty would enhance the prognostic properties of GRACE.: Methods ... for myocardial infarction (external validation). Frailty was assessed using the Clinical Frailty Scale (CFS). The GRACE 2.0 ...

Abstract	Background: Risk prediction after myocardial infarction is often complex in older patients. The Global Registry of Acute Coronary Events (GRACE) model includes clinical parameters and age, but not frailty. We hypothesised that frailty would enhance the prognostic properties of GRACE. Methods: We performed a prospective observational cohort study in two independent cardiology units: the Royal Infirmary of Edinburgh, UK (primary cohort) and the South Yorkshire Cardiothoracic Centre, Sheffield, UK (external validation). The study sample included 198 patients ≥65 years old hospitalised with type 1 myocardial infarction (primary cohort) and 96 patients ≥65 years old undergoing cardiac catheterisation for myocardial infarction (external validation). Frailty was assessed using the Clinical Frailty Scale (CFS). The GRACE 2.0 estimated risk of 12-month mortality, Charlson comorbidity index and Karnofsky disability scale were also determined for each patient. Results: Forty (20%) patients were frail (CFS ≥5). These individuals had greater comorbidity, functional impairment and a higher risk of death at 12 months (49% vs. 9% in non-frail patients, p < 0.001). The hazard of 12-month all-cause mortality nearly doubled per point increase in CFS after adjustment for age, sex and comorbidity (Hazard Ratio [HR] 1.90, 95% CI 1.47-2.44, p < 0.001). The CFS had good discrimination for mortality by Receiver Operating Characteristic (ROC) curve analysis (Area Under the Curve [AUC] 0.81, 95% CI 0.72-0.89) and enhanced the GRACE estimate (AUC 0.86 vs. 0.80 without CFS, p = 0.04). At existing GRACE thresholds, the CFS resulted in a Net Reclassification Improvement (NRI) of 0.44 (95% CI 0.28-0.60, p < 0.001), largely through reductions in risk estimates amongst non-frail patients. Similar findings were observed in the external validation cohort (NRI 0.46, 95% CI 0.23-0.69, p < 0.001). Conclusions: The GRACE score overestimated mortality risk after myocardial infarction in these cohorts of older patients. The CFS is a simple guided frailty tool that may enhance prediction in this setting. These findings merit evaluation in larger cohorts of unselected patients. Trial registration: Clinicaltrials.gov; NCT02302014 (November 26th 2014, retrospectively registered).
MeSH term(s)	Acute Coronary Syndrome/complications ; Acute Coronary Syndrome/epidemiology ; Aged ; Aged, 80 and over ; Angiotensin Receptor Antagonists ; Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; Cohort Studies ; Female ; Frailty/diagnosis ; Humans ; Male ; Myocardial Infarction/diagnosis ; Myocardial Infarction/drug therapy ; Myocardial Infarction/epidemiology ; Prognosis ; Prospective Studies ; Registries ; Risk Assessment/methods ; Risk Factors
Chemical Substances	Angiotensin Receptor Antagonists ; Angiotensin-Converting Enzyme Inhibitors
Language	English
Publishing date	2020-03-13
Publishing country	England
Document type	Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
ZDB-ID	2059865-8
ISSN	1471-2318 ; 1471-2318
ISSN (online)	1471-2318
ISSN	1471-2318
DOI	10.1186/s12877-020-1500-9
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Article ; Online: Arctic Sea level Budget Assessment During the GRACE/Argo Time Period

Roshin P. Raj / Ole B. Andersen / Johnny A. Johannessen / Benjamin D. Gutknecht / Sourav Chatterjee / Stine K. Rose / Antonio Bonaduce / Martin Horwath / Heidi Ranndal / Kristin Richter / Hindumathi Palanisamy / Carsten A. Ludwigsen / Laurent Bertino / J. Even Ø. Nilsen / Per Knudsen / Anna Hogg / Anny Cazenave / Jérôme Benveniste

Remote Sensing, Vol 12, Iss 2837, p

2020 Volume 2837

Abstract: ... with major changes in the processing techniques; (2) ocean mass change data derived from GRACE satellite ... gravimetry; (3) and steric height estimated from gridded hydrographic data for the GRACE/Argo time period ...

Abstract	Sea level change is an important indicator of climate change. Our study focuses on the sea level budget assessment of the Arctic Ocean using: (1) the newly reprocessed satellite altimeter data with major changes in the processing techniques; (2) ocean mass change data derived from GRACE satellite gravimetry; (3) and steric height estimated from gridded hydrographic data for the GRACE/Argo time period (2003–2016). The Beaufort Gyre (BG) and the Nordic Seas (NS) regions exhibit the largest positive trend in sea level during the study period. Halosteric sea level change is found to dominate the area averaged sea level trend of BG, while the trend in NS is found to be influenced by halosteric and ocean mass change effects. Temporal variability of sea level in these two regions reveals a significant shift in the trend pattern centered around 2009–2011. Analysis suggests that this shift can be explained by a change in large-scale atmospheric circulation patterns over the Arctic. The sea level budget assessment of the Arctic found a residual trend of more than 1.0 mm/yr. This nonclosure of the sea level budget is further attributed to the limitations of the three above mentioned datasets in the Arctic region.
Keywords	sea level ; satellite altimetry ; GRACE ; ocean mass change ; steric height ; Arctic Oscillation ; Science ; Q
Language	English
Publishing date	2020-09-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: The Impact of New Accelerometer Transplant Data (ACH) on GRACE Follow‐On Along‐Orbit Inter‐Satellite Laser Ranging Observations and Monthly Time‐Variable Gravity and Mascon Solutions

Ghobadi‐Far, Khosro / Werth, Susanna / Shirzaei, Manoochehr / Loomis, Bryant D. / Döhne, Thorben / Willen, Matthias O. / Horwath, Martin

Journal of Geophysical Research: Solid Earth. 2023 June, v. 128, no. 6 p.e2023JB026740-

2023

Abstract: GRACE‐D accelerometer data show significant bias jumps since one month after the launch ... of the GRACE Follow‐On (GRACE‐FO) satellites in May 2018, making them inapplicable for correcting GRACE‐FO ... products for non‐gravitational accelerations. The GRACE‐FO Science Data System (SDS) compensated this issue ...

Abstract	GRACE‐D accelerometer data show significant bias jumps since one month after the launch of the GRACE Follow‐On (GRACE‐FO) satellites in May 2018, making them inapplicable for correcting GRACE‐FO products for non‐gravitational accelerations. The GRACE‐FO Science Data System (SDS) compensated this issue by transplanting the GRACE‐C accelerometer data toward that of GRACE‐D. Recently, GRACE‐FO SDS implemented an updated transplant method, used in the latest release of GRACE‐FO data. Here, we examine the impact of updated accelerometer transplant data (ACH) on GRACE‐FO measurements at all levels: (a) Level‐1B inter‐satellite laser ranging residuals measured along satellite orbit, (b) Level‐2 time‐variable gravity solutions from all SDS centers (JPL, CSR, and GFZ), and (c) Level‐3 mascon solutions. We show that inter‐satellite laser ranging residuals are modified at low frequencies below 1 mHz, affecting the along‐orbit analysis of large‐scale time‐variable gravity signals. When mapped into monthly Level‐2 spherical harmonic coefficients of geopotential, the low‐frequency change in inter‐satellite ranging residuals leads to substantial improvement of coefficients associated with resonant orders (i.e., 15, 30, 45, etc.) and C₃₀. We also present an improved SLR‐derived C₃₀ which significantly improves the agreement with updated GRACE‐FO C₃₀ at seasonal and interannual timescales. Moreover, we demonstrate the noise reduction in mass change estimates from new GRACE‐FO Level‐2 data over oceans, Greenland, and Antarctica for all SDS solutions. GRACE‐FO mascon solutions show a moderate change in the updated release. Our comprehensive analyses demonstrate high‐quality estimates of non‐gravitational accelerations by the updated transplant method, resulting in more accurate GRACE‐FO time‐variable gravity and mass change observations.
Keywords	accelerometers ; geophysics ; gravity ; research ; satellites ; Antarctica ; Greenland
Language	English
Dates of publication	2023-06
Publishing place	John Wiley & Sons, Ltd
Document type	Article ; Online
Note	JOURNAL ARTICLE
ISSN	2169-9313
DOI	10.1029/2023JB026740
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: In-Orbit Performance of the GRACE Follow-on Laser Ranging Interferometer.

Abich, Klaus / Abramovici, Alexander / Amparan, Bengie / Baatzsch, Andreas / Okihiro, Brian Bachman / Barr, David C / Bize, Maxime P / Bogan, Christina / Braxmaier, Claus / Burke, Michael J / Clark, Ken C / Dahl, Christian / Dahl, Katrin / Danzmann, Karsten / Davis, Mike A / de Vine, Glenn / Dickson, Jeffrey A / Dubovitsky, Serge / Eckardt, Andreas /

Ester, Thomas / Barranco, Germán Fernández / Flatscher, Reinhold / Flechtner, Frank / Folkner, William M / Francis, Samuel / Gilbert, Martin S / Gilles, Frank / Gohlke, Martin / Grossard, Nicolas / Guenther, Burghardt / Hager, Philipp / Hauden, Jerome / Heine, Frank / Heinzel, Gerhard / Herding, Mark / Hinz, Martin / Howell, James / Katsumura, Mark / Kaufer, Marina / Klipstein, William / Koch, Alexander / Kruger, Micah / Larsen, Kameron / Lebeda, Anton / Lebeda, Arnold / Leikert, Thomas / Liebe, Carl Christian / Liu, Jehhal / Lobmeyer, Lynette / Mahrdt, Christoph / Mangoldt, Thomas / McKenzie, Kirk / Misfeldt, Malte / Morton, Phillip R / Müller, Vitali / Murray, Alexander T / Nguyen, Don J / Nicklaus, Kolja / Pierce, Robert / Ravich, Joshua A / Reavis, Gretchen / Reiche, Jens / Sanjuan, Josep / Schütze, Daniel / Seiter, Christoph / Shaddock, Daniel / Sheard, Benjamin / Sileo, Michael / Spero, Robert / Spiers, Gary / Stede, Gunnar / Stephens, Michelle / Sutton, Andrew / Trinh, Joseph / Voss, Kai / Wang, Duo / Wang, Rabi T / Ware, Brent / Wegener, Henry / Windisch, Steve / Woodruff, Christopher / Zender, Bernd / Zimmermann, Marcus

Physical review letters

2015 Volume 123, Issue 3, Page(s) 31101

Abstract: ... GRACE) Follow-On mission has provided the first laser interferometric range measurements between remote ...

Abstract	The Laser Ranging Interferometer (LRI) instrument on the Gravity Recovery and Climate Experiment (GRACE) Follow-On mission has provided the first laser interferometric range measurements between remote spacecraft, separated by approximately 220 km. Autonomous controls that lock the laser frequency to a cavity reference and establish the 5 degrees of freedom two-way laser link between remote spacecraft succeeded on the first attempt. Active beam pointing based on differential wave front sensing compensates spacecraft attitude fluctuations. The LRI has operated continuously without breaks in phase tracking for more than 50 days, and has shown biased range measurements similar to the primary ranging instrument based on microwaves, but with much less noise at a level of 1 nm/sqrt[Hz] at Fourier frequencies above 100 mHz.
Language	English
Publishing date	2015-09-30
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.123.031101
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Article ; Online: The Rapid and Steady Mass Loss of the Patagonian Icefields throughout the GRACE Era

Andreas Richter / Andreas Groh / Martin Horwath / Erik Ivins / Eric Marderwald / José Luis Hormaechea / Raúl Perdomo / Reinhard Dietrich

Remote Sensing, Vol 11, Iss 8, p

2002–2017

2019 Volume 909

Abstract: We use the complete gravity recovery and climate experiment (GRACE) Level-2 monthly time series ... in the ocean, in the continental water storage, and of the Antarctic ice sheet. The 161 monthly GRACE gravity ...

Abstract	We use the complete gravity recovery and climate experiment (GRACE) Level-2 monthly time series to derive the ice mass changes of the Patagonian Icefields (Southern Andes). The glacial isostatic adjustment is accounted for by a regional model that is constrained by global navigation satellite systems (GNSS) uplift observations. Further corrections are applied concerning the effect of mass variations in the ocean, in the continental water storage, and of the Antarctic ice sheet. The 161 monthly GRACE gravity field solutions are inverted in the spatial domain through the adjustment of scaling factors applied to a-priori ice mass change patterns based on published remote sensing results for the Southern and Northern Patagonian Icefields, respectively. We infer an ice mass change rate of −24.4 ± 4.7 Gt/a for the Patagonian Icefields between April 2002 and June 2017, which corresponds to a contribution to the eustatic sea level rise of 0.067 ± 0.013 mm/a. Our time series of monthly ice mass changes reveals no indication for an acceleration in ice mass loss. We find indications that the Northern Patagonian Icefield contributes more to the integral ice loss than previously assumed.
Keywords	ice mass ; satellite gravimetry ; Patagonia ; GRACE ; Science ; Q
Subject code	550
Language	English
Publishing date	2019-04-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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