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  1. Book ; Online ; E-Book: Cell assembly with 3D bioprinting

    He, Yong / Gao, Qing / Jin, Yifei

    2022  

    Author's details Yong He, Qing Gao, Yifei Jin
    Keywords Three-dimensional imaging in biology ; Three-dimensional printing/Equipment and supplies
    Subject code 610.28
    Language English
    Size 1 online resource (371 pages)
    Publisher Wiley-VCH
    Publishing place Weinheim, Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-527-82857-5 ; 3-527-82859-1 ; 3-527-82858-3 ; 9783527347964 ; 978-3-527-82857-9 ; 978-3-527-82859-3 ; 978-3-527-82858-6 ; 3527347968
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Integrating high-volume molecular and morphological data into the evolutionary studies of

    He, Xing-Jin

    Plant diversity

    2023  Volume 46, Issue 1, Page(s) 1–2

    Language English
    Publishing date 2023-12-14
    Publishing country China
    Document type Journal Article
    ZDB-ID 2873411-7
    ISSN 2468-2659 ; 2095-0845
    ISSN (online) 2468-2659
    ISSN 2095-0845
    DOI 10.1016/j.pld.2023.12.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Nearest neighbor bit assisted decision scheme for ISI mitigation in optical camera communications.

    Shi, Jin / He, Jing

    Optics letters

    2024  Volume 49, Issue 7, Page(s) 1836–1839

    Abstract: To enable a higher transmission rate in optical camera communication (OCC) systems, severe inter-symbol interference (ISI) occurs owing to the reduction of the number of pixel-row-per-bit (PPB). Therefore, those pixels representing data bit 0 or 1 may ... ...

    Abstract To enable a higher transmission rate in optical camera communication (OCC) systems, severe inter-symbol interference (ISI) occurs owing to the reduction of the number of pixel-row-per-bit (PPB). Therefore, those pixels representing data bit 0 or 1 may have same gray scale values, significantly deteriorating the bit decision when using the conventional thresholding scheme. In this Letter, a simple yet efficient scheme, referred to as nearest neighbor bit assisted decision (NNBAD) scheme, is proposed and experimentally demonstrated for signal decision in OCC systems. NNBAD leverages the nearest neighbor bit to jointly assist bit decision for pixels with severe ISI. Experimental results show that, for OCC systems with on-off keying (OOK) modulation, those pixels with severe ISI cannot be distinguished by the conventional thresholding scheme. Yet, the NNBAD scheme exhibits strong robustness against ISI, remarkably improving the bit error rate (BER) performance. The proposed scheme can achieve a throughput of 8.2 kbps with OOK modulation under an illuminance of 600 lx.
    Language English
    Publishing date 2024-04-01
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4794
    ISSN (online) 1539-4794
    DOI 10.1364/OL.520900
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Online: Plant diversity of Southeast Asia-II

    Jin, Xiao-Hua / Xia, Nian He / Tan, Yun Hong

    2020  

    Abstract: The special issue of plant diversity in Southeast Asia will focus on the documentation of new discoveries in SE Asia. There are four global biodiversity hotspots in Southeast Asia. Although there are many plans to protect this rich biodiversity, however, ...

    Abstract The special issue of plant diversity in Southeast Asia will focus on the documentation of new discoveries in SE Asia. There are four global biodiversity hotspots in Southeast Asia. Although there are many plans to protect this rich biodiversity, however, the rich biodiversity in SE Asia is under threat due to economic development and population growth. There is a huge gap between our knowledge and biodiversity in SE Asia. During the last six investigations, many new taxa, including new species, new genera, have been discovered. This special issue will bring the rich but little known biodiversity to the public and protect them
    Keywords Botany
    Size 1 electronic resource (240 pages)
    Publisher Pensoft Publishers
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020481467
    ISBN 9789546429919 ; 9546429910
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article ; Online: Combination of On-Line and Off-Line Two-Dimensional Liquid Chromatography-Mass Spectrometry for Comprehensive Characterization of mAb Charge Variants and Precise Instructions for Rapid Process Development.

    Jin, Xiaoqing / He, Bingfang

    International journal of molecular sciences

    2023  Volume 24, Issue 20

    Abstract: Charge variants, as an important quality attribute of mAbs, must be comprehensively characterized and monitored during development. However, due to their complex structure, the characterization of charge variants is challenging, labor-intensive, and time- ...

    Abstract Charge variants, as an important quality attribute of mAbs, must be comprehensively characterized and monitored during development. However, due to their complex structure, the characterization of charge variants is challenging, labor-intensive, and time-consuming when using traditional approaches. This work combines on-line and off-line 2D-LC-MS to comprehensively characterize mAb charge variants and quickly offer precise instructions for process development. Six charge variant peaks of mAb 1 were identified using the developed platform. Off-line 2D-LC-MS analysis at the peptide level showed that the acidic peak P1 and the basic peaks P4 and P5 were caused by the deamidation of asparagine, the oxidation of methionine, and incomplete C-terminal K loss, respectively. On-line 2D-LC-MS at the intact protein level was used to identify the root causes, and it was found that the acidic peak P2 and the basic peak P6 were due to the glutathionylation of cysteine and succinimidation of aspartic acid, respectively, which were not found in off-line 2D-LC-MS because of the loss occurring during pre-treatment. These results suggest that process development could focus on cell culture for adjustment of glutathionylation. In this paper, we propose the concept of precision process development based on on-line 2D-LC-MS, which could quickly offer useful data with only 0.6 mg mAb within 6 h for precise instructions for process development. Overall, the combination of on-line and off-line 2D-LC-MS can characterize mAb charge variants more comprehensively, precisely, and quickly than other approaches. This is a very effective platform with routine operations that provides precise instructions for process development within hours, and will help to accelerate the development of innovative therapeutics.
    MeSH term(s) Antibodies, Monoclonal/chemistry ; Chromatography, Liquid ; Mass Spectrometry/methods ; Peptides
    Chemical Substances Antibodies, Monoclonal ; Peptides
    Language English
    Publishing date 2023-10-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms242015184
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Electrochemotherapy for Pancreatic Cancer: An Emerging Treatment Modality?

    He, Jin

    Annals of surgical oncology

    2020  Volume 27, Issue 11, Page(s) 4086–4087

    MeSH term(s) Electrochemotherapy ; Humans ; Pancreatic Neoplasms/drug therapy ; Treatment Outcome
    Language English
    Publishing date 2020-07-04
    Publishing country United States
    Document type Editorial
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-020-08791-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Research on gesture recognition algorithm based on MME-P3D.

    Jin, Hongmei / He, Ning / Liu, Boyu / Li, Zhanli

    Mathematical biosciences and engineering : MBE

    2024  Volume 21, Issue 3, Page(s) 3594–3617

    Abstract: A Multiscale-Motion Embedding Pseudo-3D (MME-P3D) gesture recognition algorithm has been proposed to tackle the issues of excessive parameters and high computational complexity encountered by existing gesture recognition algorithms deployed in mobile and ...

    Abstract A Multiscale-Motion Embedding Pseudo-3D (MME-P3D) gesture recognition algorithm has been proposed to tackle the issues of excessive parameters and high computational complexity encountered by existing gesture recognition algorithms deployed in mobile and embedded devices. The algorithm initially takes into account the characteristics of gesture motion information, integrating the channel attention (CE) mechanism into the pseudo-3D (P3D) module, thereby constructing a P3D-C feature extraction network that can efficiently extract spatio-temporal feature information while reducing the complexity of the algorithmic model. To further enhance the understanding and learning of the global gesture movement's dynamic information, a Multiscale Motion Embedding (MME) mechanism is subsequently designed. The experimental findings reveal that the MME-P3D model achieves recognition accuracies reaching up to 91.12% and 83.06% on the self-constructed conference gesture dataset and the publicly available Chalearn 2013 dataset, respectively. In comparison with the conventional 3D convolutional neural network, the MME-P3D model demonstrates a significant advantage in terms of parameter count and computational requirements, which are reduced by as much as 82% and 83%, respectively. This effectively addresses the limitations of the original algorithms, making them more suitable for deployment on embedded and mobile devices and providing a more effective means for the practical application of hand gesture recognition technology.
    MeSH term(s) Gestures ; Pattern Recognition, Automated ; Algorithms ; Neural Networks, Computer ; Endrin/analogs & derivatives
    Chemical Substances MME (78185-58-7) ; Endrin (OB9NVE7YCL)
    Language English
    Publishing date 2024-03-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2265126-3
    ISSN 1551-0018 ; 1551-0018
    ISSN (online) 1551-0018
    ISSN 1551-0018
    DOI 10.3934/mbe.2024158
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Synthesis and antimicrobial studies of cadasides analogues via on-resin esterification.

    Yan, Xiangzhen / He, Chengshuo / Li, Zhuang / Jin, Kang

    Bioorganic & medicinal chemistry

    2024  Volume 99, Page(s) 117601

    Abstract: A series of cadasides analogues have been prepared via a combination of solid-phase peptide synthesis and solution-phase cyclization. Primary structure-activity relationship studies of cadasides have also been established and revealed the critical roles ... ...

    Abstract A series of cadasides analogues have been prepared via a combination of solid-phase peptide synthesis and solution-phase cyclization. Primary structure-activity relationship studies of cadasides have also been established and revealed the critical roles of unnatural amino acid residues, which will facilitate the further development of cadasides analogues with improved antimicrobial activities.
    MeSH term(s) Esterification ; Anti-Infective Agents/pharmacology ; Structure-Activity Relationship ; Cyclization
    Chemical Substances Anti-Infective Agents
    Language English
    Publishing date 2024-01-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 1161284-8
    ISSN 1464-3391 ; 0968-0896
    ISSN (online) 1464-3391
    ISSN 0968-0896
    DOI 10.1016/j.bmc.2024.117601
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Mechanical and Fire Properties of Flame-Retardant Laminated Bamboo Lumber Glued with Phenol Formaldehyde and Melamine Urea Formaldehyde Adhesives.

    He, Ying / Jin, Xiaobei / Li, Jingpeng / Qin, Daochun

    Polymers

    2024  Volume 16, Issue 6

    Abstract: This study investigated the effects of different adhesives, phenol formaldehyde (PF) and melamine urea formaldehyde (MUF), on the mechanical and fire properties of flame-retardant laminated bamboo lumber (LBL). The results demonstrated that the flame- ... ...

    Abstract This study investigated the effects of different adhesives, phenol formaldehyde (PF) and melamine urea formaldehyde (MUF), on the mechanical and fire properties of flame-retardant laminated bamboo lumber (LBL). The results demonstrated that the flame-retardant treatment using phosphorus-nitrogen-boron compounds endowed the LBL with excellent flame retardancy and smoke suppression properties, even though the bending strength and bond shear strength were slightly reduced. The PF-glued LBL exhibited superior mechanical and shear properties to the MUF-glued ones, primarily due to its higher processing temperature and deeper adhesive penetration. In addition, the MUF-glued flame-retardant LBL displayed better heat release reduction and smoke suppression properties than the PF-glued LBL, which resulted from the synergistic flame retardancy between the melamine element in MUF and the applied flame retardant. The analysis of the influence of adhesive type on the mechanical and fire properties of flame-retardant LBL holds significant importance for the future design and production of high-performance LBL material.
    Language English
    Publishing date 2024-03-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym16060781
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Advances in tumor vascular growth inhibition.

    Zhang, Keyong / Shi, Yuanyuan / Jin, Ze / He, Jian

    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

    2024  

    Abstract: Tumor growth and metastasis require neovascularization, which is dependent on a complex array of factors, such as the production of various pro-angiogenic factors by tumor cells, intercellular signaling, and stromal remodeling. The hypoxic, acidic tumor ... ...

    Abstract Tumor growth and metastasis require neovascularization, which is dependent on a complex array of factors, such as the production of various pro-angiogenic factors by tumor cells, intercellular signaling, and stromal remodeling. The hypoxic, acidic tumor microenvironment is not only conducive to tumor cell proliferation, but also disrupts the equilibrium of angiogenic factors, leading to vascular heterogeneity, which further promotes tumor development and metastasis. Anti-angiogenic strategies to inhibit tumor angiogenesis has, therefore, become an important focus for anti-tumor therapy. The traditional approach involves the use of anti-angiogenic drugs to inhibit tumor neovascularization by targeting upstream and downstream angiogenesis-related pathways or pro-angiogenic factors, thereby inhibiting tumor growth and metastasis. This review explores the mechanisms involved in tumor angiogenesis and summarizes currently used anti-angiogenic drugs, including monoclonal antibody, and small-molecule inhibitors, as well as the progress and challenges associated with their use in anti-tumor therapy. It also outlines the opportunities and challenges of treating tumors using more advanced anti-angiogenic strategies, such as immunotherapy and nanomaterials.
    Language English
    Publishing date 2024-03-20
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 2397359-6
    ISSN 1699-3055 ; 1699-048X
    ISSN (online) 1699-3055
    ISSN 1699-048X
    DOI 10.1007/s12094-024-03432-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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