LIVIVO - Search results -

Search results

Result 1 - 10 of total 279

Search options

Article ; Online: Analytical techniques for screening of cannabis and derivatives from human hair specimens.

Kale, Rohit / Chaturvedi, Deepa / Dandekar, Prajakta / Jain, Ratnesh

Analytical methods : advancing methods and applications

2024 Volume 16, Issue 8, Page(s) 1133–1149

Abstract: Cannabis and associated substances are some of the most frequently abused drugs across the globe, mainly due to their anxiolytic and euphorigenic properties. Nowadays, the analysis of hair samples has been given high importance in forensic and analytical ...

Abstract	Cannabis and associated substances are some of the most frequently abused drugs across the globe, mainly due to their anxiolytic and euphorigenic properties. Nowadays, the analysis of hair samples has been given high importance in forensic and analytical sciences and in clinical studies because they are associated with a low risk of infection, do not require complicated storage conditions, and offer a broad window of non-invasive detection. Analysis of hair samples is very easy compared to the analysis of blood, urine, and saliva samples. This review places particular emphasis on methodologies of analyzing hair samples containing cannabis, with a special focus on the preparation of samples for analysis, which involves screening and extraction techniques, followed by confirmatory assays. Through this manuscript, we have presented an overview of the available literature on the screening of cannabis using mass spectroscopy techniques. We have presented a detailed overview of the advantages and disadvantages of this technique, to establish it as a suitable method for the analysis of cannabis from hair samples.
MeSH term(s)	Humans ; Cannabis ; Substance Abuse Detection/methods ; Hallucinogens/analysis ; Illicit Drugs/analysis ; Cannabinoid Receptor Agonists/analysis ; Hair/chemistry
Chemical Substances	Hallucinogens ; Illicit Drugs ; Cannabinoid Receptor Agonists
Language	English
Publishing date	2024-02-22
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2515210-5
ISSN	1759-9679 ; 1759-9660
ISSN (online)	1759-9679
ISSN	1759-9660
DOI	10.1039/d3ay00786c
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article: Disease-related biomarkers as experimental endpoints in 3D skin culture models.

Chaturvedi, Deepa / Paranjape, Swarali / Jain, Ratnesh / Dandekar, Prajakta

Cytotechnology

2023 Volume 75, Issue 3, Page(s) 165–193

Abstract: The success of in vitro 3D models in either recapitulating the normal tissue physiology or altered physiology or disease condition depends upon the identification and/or quantification of relevant biomarkers that confirm the functionality of these models. ...

Abstract	The success of in vitro 3D models in either recapitulating the normal tissue physiology or altered physiology or disease condition depends upon the identification and/or quantification of relevant biomarkers that confirm the functionality of these models. Various skin disorders, such as psoriasis, photoaging, vitiligo, etc., and cancers like squamous cell carcinoma and melanoma, etc. have been replicated via organotypic models. The disease biomarkers expressed by such cell cultures are quantified and compared with the biomarkers expressed in cultures depicting the normal tissue physiology, to identify the most prominent variations in their expression. This may also indicate the stage or reversal of these conditions upon treatment with relevant therapeutics. This review article presents an overview of the important biomarkers that have been identified in Supplementary information: The online version contains supplementary material available at 10.1007/s10616-023-00574-2.
Language	English
Publishing date	2023-04-03
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1035772-5
ISSN	0920-9069
ISSN	0920-9069
DOI	10.1007/s10616-023-00574-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 2604: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Predictive analysis of COVID-19 eradication with vaccination in India, Brazil, and U.S.A.

Chaturvedi, Deepa / Chakravarty, U

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases

2021 Volume 92, Page(s) 104834

Abstract: The most important question and concern in these circumstances of COVID-19 epidemic outspread is when will the pandemic end? Vaccination is the only solution to restore life to normalcy in the fastest and safest possible manner. Therefore, we have ... ...

Abstract	The most important question and concern in these circumstances of COVID-19 epidemic outspread is when will the pandemic end? Vaccination is the only solution to restore life to normalcy in the fastest and safest possible manner. Therefore, we have carried out a predictive analysis for realistic timescale estimates for overcoming the epidemic considering vaccination rate effect on the dynamics of COVID-19 control. In particular we discuss the worst affected large countries like India, Brazil and USA for estimating effect of vaccination rate in expediting the end of the COVID-19 epidemic. We analytically simulated the dynamic evolution of active cases of these countries in the last nine months using the modified SIR model and then included the effect of vaccination to forecast the proliferation dynamics. We hence obtained the transmission parameters, the variation in the reproduction numbers and the impact of the different values of the vaccination shots in the expected curves of active cases in the coming times to predicted the timescales of the end of the epidemic.
Language	English
Publishing date	2021-03-31
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2037068-4
ISSN	1567-7257 ; 1567-1348
ISSN (online)	1567-7257
ISSN	1567-1348
DOI	10.1016/j.meegid.2021.104834
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5645: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Swallowing in advanced oral cancers: A prospective observational study.

Malik, Akshat / Sharin, Florida / Balaji, Arun / Mathur, Yash / Nair, Sudhir / Chaturvedi, Pankaj / Nair, Deepa

Journal of cancer research and therapeutics

2024 Volume 20, Issue 1, Page(s) 340–348

Abstract: Background: Advanced head and neck cancers are known to cause swallowing dysfunction due to anatomical and post-treatment changes. Literature is sparse on post-surgical and/or multi-modality therapy-associated swallowing function in advanced oral ... ...

Abstract	Background: Advanced head and neck cancers are known to cause swallowing dysfunction due to anatomical and post-treatment changes. Literature is sparse on post-surgical and/or multi-modality therapy-associated swallowing function in advanced oral cancers. We conducted this study to longitudinally assess and compare the pre- and post-therapy swallowing dysfunction associated with locally advanced oral cancers. Methods and material: A prospective observational longitudinal study was conducted at a tertiary cancer center from 2017 to 2018 including treatment-naive cT4a oral cancer patients (AJCC 7th edition). The assessment was done pre-surgery, post-surgery, and post-adjuvant setting as per the scales (Dysphagia score, Penetration aspiration scale, and Yale pharyngeal residue (vallecular and pyriform fossa). Results: Of the 30 patients in the study, 47.4%, 47.4%, 52.6%, and 47.4% experienced deterioration of Dysphagia score, Penetration-Aspiration Scale (PAS), vallecula residue, and pyriform residue scores in the postoperative period. And 52.6%, 47.4%, 68.4%, and 57.9% had inferior dysphagia score, PAS, vallecula, and pyriform residue scores even 6 months after completion of adjuvant therapy. The dysphagia score correlated well with other objective assessment scores at different time points. Conclusion: Swallowing functions are significantly affected by surgery and adjuvant therapy and continue to be affected even 6 months after completion of treatment. Appropriate rehabilitation and intervention must be offered to patients to reduce this problem. Dysphagia scores can predict the swallowing status similar to other objective assessments.
MeSH term(s)	Humans ; Deglutition ; Deglutition Disorders/etiology ; Longitudinal Studies ; Prospective Studies ; Mouth Neoplasms/complications ; Mouth Neoplasms/surgery
Language	English
Publishing date	2024-03-29
Publishing country	India
Document type	Observational Study ; Journal Article
ZDB-ID	2187633-2
ISSN	1998-4138 ; 0973-1482
ISSN (online)	1998-4138
ISSN	0973-1482
DOI	10.4103/jcrt.jcrt_1499_22
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Microfluidic technology for cell biology-related applications: a review.

Mukherjee, Joydeb / Chaturvedi, Deepa / Mishra, Shlok / Jain, Ratnesh / Dandekar, Prajakta

Journal of biological physics

2023 Volume 50, Issue 1, Page(s) 1–27

Abstract: Fluid flow at the microscale level exhibits a unique phenomenon that can be explored to fabricate microfluidic devices integrated with components that can perform various biological functions. In this manuscript, the importance of physics for microscale ... ...

Abstract	Fluid flow at the microscale level exhibits a unique phenomenon that can be explored to fabricate microfluidic devices integrated with components that can perform various biological functions. In this manuscript, the importance of physics for microscale fluid dynamics using microfluidic devices has been reviewed. Microfluidic devices provide new opportunities with regard to spatial and temporal control over cell growth. Furthermore, the manuscript presents an overview of cellular stimuli observed by combining surfaces that mimic the complex biochemistries and different geometries of the extracellular matrix, with microfluidic channels regulating the transport of fluids, soluble factors, etc. We have also explained the concept of mechanotransduction, which defines the relation between mechanical force and biological response. Furthermore, the manipulation of cellular microenvironments by the use of microfluidic systems has been highlighted as a useful device for basic cell biology research activities. Finally, the article focuses on highly integrated microfluidic platforms that exhibit immense potential for biomedical and pharmaceutical research as robust and portable point-of-care diagnostic devices for the assessment of clinical samples.
MeSH term(s)	Microfluidics ; Mechanotransduction, Cellular
Language	English
Publishing date	2023-12-06
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	2016734-9
ISSN	1573-0689 ; 0092-0606
ISSN (online)	1573-0689
ISSN	0092-0606
DOI	10.1007/s10867-023-09646-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Predictive analysis of COVID-19 eradication with vaccination in India, Brazil, and U.S.A

Chaturvedi, Deepa / Chakravarty, U

Infection, genetics, and evolution. 2021 Aug., v. 92

2021

Abstract	The most important question and concern in these circumstances of COVID-19 epidemic outspread is when will the pandemic end? Vaccination is the only solution to restore life to normalcy in the fastest and safest possible manner. Therefore, we have carried out a predictive analysis for realistic timescale estimates for overcoming the epidemic considering vaccination rate effect on the dynamics of COVID-19 control. In particular we discuss the worst affected large countries like India, Brazil and USA for estimating effect of vaccination rate in expediting the end of the COVID-19 epidemic. We analytically simulated the dynamic evolution of active cases of these countries in the last nine months using the modified SIR model and then included the effect of vaccination to forecast the proliferation dynamics. We hence obtained the transmission parameters, the variation in the reproduction numbers and the impact of the different values of the vaccination shots in the expected curves of active cases in the coming times to predicted the timescales of the end of the epidemic.
Keywords	COVID-19 infection ; evolution ; genetics ; infection ; models ; pandemic ; reproduction ; vaccination ; Brazil ; India
Language	English
Dates of publication	2021-08
Publishing place	Elsevier B.V.
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	2037068-4
ISSN	1567-1348
ISSN	1567-1348
DOI	10.1016/j.meegid.2021.104834
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Cologne/Königswinter

Zs.A 5645: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Biotransformation of ricinoleic acid to γ-decalactone using novel yeast strains and process optimization by applying Taguchi model.

Singh, Suman / Deepa, Nikky / Rastogi, Dheerendra / Chaturvedi, Shivani / Syed, Naziya / Singh, Akanksha / Nannaware, Ashween Deepak / Rout, Prasant Kumar

Journal of biotechnology

2023 Volume 377, Page(s) 34–42

Abstract: Flavour molecules are generated now-a-days through microbial fermentation on a commercial scale. γ-Decalactone (GDL) is an important molecule due to its long-lasting flavouring impact as buttery, coconut and peach-type. In the current study, 33 ... ...

Abstract	Flavour molecules are generated now-a-days through microbial fermentation on a commercial scale. γ-Decalactone (GDL) is an important molecule due to its long-lasting flavouring impact as buttery, coconut and peach-type. In the current study, 33 microorganisms were isolated from different fruit sources, and their screening for target GDL production was performed. Using DNA sequencing, two potential strains yielding good amounts of GDL were identified from pineapple and strawberry fruits. The identified strains were Metschnikowia vanudenii (OP954735) and Candida parapsilosis (OP954733), and further optimized by Taguchi method. The effectiveness of lactone production is influenced by the rate of microbial growth under various operating conditions. The factors such as substrate concentration, pH, temperature, cell density and rotation (rpm) with 3 levels were applied for the GDL production using M. vanudenii (OP954735) and C. parapsilosis (OP954733) strains. The results revealed that the highest molar conversion of GDL was 24.69% (115.7 mg/g quantitative yield) and 52.69% (272.0 mg/g quantitative yield) at the optimal conditions using SB-62 and PA-19 strains, respectively. The two novel strains are reported for the first time for production of γ-decalactone and overall, this study opens up the possibility of using Taguchi design for large scale up process development for producing food flavours utilising environmentally friendly natural strains.
MeSH term(s)	Yeasts/genetics ; Yeasts/metabolism ; Lactones/chemistry ; Biotransformation
Chemical Substances	ricinoleic acid (I2D0F69854) ; decan-4-olide (7HLS05KP9O) ; Lactones
Language	English
Publishing date	2023-10-15
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	843647-2
ISSN	1873-4863 ; 0168-1656 ; 1389-0352
ISSN (online)	1873-4863
ISSN	0168-1656 ; 1389-0352
DOI	10.1016/j.jbiotec.2023.10.004
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2299: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Conference proceedings: Role of anaesthesiologist in neuroendovascular intervention

Chaturvedi, Deepa

Journal of Neuroanaesthesiology and Critical Care

2016 Volume 03, Issue 02

Event/congress	17th Annual Conference of Indian Society of Neuroanaesthesiology and Critical Care, Bengaluru, India, 2016-02-05
Language	English
Publishing date	2016-04-01
Publisher	Thieme Medical and Scientific Publishers Private Ltd.
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	2937287-2
ISSN	2348-926X ; 2348-0548
ISSN (online)	2348-926X
ISSN	2348-0548
DOI	10.1055/s-0038-1667594
Database	Thieme publisher's database

Order via subito

Article ; Online: Recent progress and major gaps in the vaccine development for African swine fever.

Chandana, M S / Nair, Sonu S / Chaturvedi, V K / Abhishek / Pal, Santanu / Charan, Manchikanthi Sri Sai / Balaji, Shilpa / Saini, Shubham / Vasavi, Koppu / Deepa, Poloju

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology

2024 Volume 55, Issue 1, Page(s) 997–1010

Abstract: The swine industry across the globe is recently facing a devastating situation imparted by a highly contagious and deadly viral disease, African swine fever. The disease is caused by a DNA virus, the African swine fever virus (ASFV) of the genus ... ...

Abstract	The swine industry across the globe is recently facing a devastating situation imparted by a highly contagious and deadly viral disease, African swine fever. The disease is caused by a DNA virus, the African swine fever virus (ASFV) of the genus Asfivirus. ASFV affects both wild boars and domestic pigs resulting in an acute form of hemorrhagic fever. Since the first report in 1921, the disease remains endemic in some of the African countries. However, the recent occurrence of ASF outbreaks in Asia led to a fresh and formidable challenge to the global swine production industry. Culling of the infected animals along with the implementation of strict sanitary measures remains the only options to control this devastating disease. Efforts to develop an effective and safe vaccine against ASF began as early as in the mid-1960s. Different approaches have been employed for the development of effective ASF vaccines including inactivated vaccines, subunit vaccines, DNA vaccines, virus-vectored vaccines, and live attenuated vaccines (LAVs). Inactivated vaccines are a non-feasible strategy against ASF due to their inability to generate a complete cellular immune response. However genetically engineered vaccines, such as subunit vaccines, DNA vaccines, and virus vector vaccines, represent tailored approaches with minimal adverse effects and enhanced safety profiles. As per the available data, gene deleted LAVs appear to be the most potential vaccine candidates. Currently, a gene deleted LAV (ASFV-G-∆I177L), developed in Vietnam, stands as the sole commercially available vaccine against ASF. The major barrier to the goal of developing an effective vaccine is the critical gaps in the knowledge of ASFV biology and the immune response induced by ASFV infection. The precise contribution of various hosts, vectors, and environmental factors in the virus transmission must also be investigated in depth to unravel the disease epidemiology. In this review, we mainly focus on the recent progress in vaccine development against ASF and the major gaps associated with it.
MeSH term(s)	Swine ; Animals ; African Swine Fever/prevention & control ; African Swine Fever/epidemiology ; African Swine Fever Virus/genetics ; Vaccines, DNA/genetics ; Sus scrofa ; Viral Vaccines/genetics ; Vaccines, Attenuated/genetics ; Vaccine Development ; Vaccines, Inactivated ; Vaccines, Subunit
Chemical Substances	Vaccines, DNA ; Viral Vaccines ; Vaccines, Attenuated ; Vaccines, Inactivated ; Vaccines, Subunit
Language	English
Publishing date	2024-02-05
Publishing country	Brazil
Document type	Journal Article ; Review
ZDB-ID	2017175-4
ISSN	1678-4405 ; 1517-8382
ISSN (online)	1678-4405
ISSN	1517-8382
DOI	10.1007/s42770-024-01264-7
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Critical Review of the Current Evidence on Sentinel Node Biopsy in Oral Cancer.

Singh, Arjun / Roy, Satadru / Tuljapurkar, Vidisha / Nair, Deepa / Chaturvedi, Pankaj

Current oncology reports

2022 Volume 24, Issue 6, Page(s) 783–791

Abstract: Purpose of review: With contemporary surgery of the cN0 neck in early oral cancer becoming more selective, sentinel node biopsy (SNB) is gaining popularity as a possible alternate option to elective neck dissection (END). This review attempts to ... ...

Abstract	Purpose of review: With contemporary surgery of the cN0 neck in early oral cancer becoming more selective, sentinel node biopsy (SNB) is gaining popularity as a possible alternate option to elective neck dissection (END). This review attempts to critically appraise the current evidence and highlight pertinent arguments for the use of SNB in early oral cancers. Recent findings: Based on the recent randomized trials, it is imperative to perform an END at the time of primary resection in cN0 oral cancers. The much criticized false negative rate of SNB can be argued to be equal to the regional failure rate after END for pN0 necks, possibly making a case for SNB due to the reduction in number of neck dissections. There still lies ambiguity on the technique, protocols, and benefit of SNB over END. The role of extended histopathological techniques and the implications of micrometastasis and isolated tumor cells for treatment intensification remain questionable. Currently, SNB is an intermediary between routine imaging and END that needs to evolve before it can become a practice changing alternative to END itself. More efforts are needed in standardizing the protocols for SNB.
MeSH term(s)	Carcinoma, Squamous Cell/pathology ; Humans ; Mouth Neoplasms/pathology ; Mouth Neoplasms/surgery ; Neck Dissection/methods ; Neoplasm Staging ; Sentinel Lymph Node Biopsy
Language	English
Publishing date	2022-03-17
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2057359-5
ISSN	1534-6269 ; 1523-3790
ISSN (online)	1534-6269
ISSN	1523-3790
DOI	10.1007/s11912-021-01171-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 5521: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

To top

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito