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  1. Article ; Online: Impact of

    Razanamahery, Jerome / Godot, Amelie / Leguy-Seguin, Vanessa / Samson, M / Audia, Sylvain / Bonnotte, Bernard

    Frontiers in immunology

    2023  Volume 14, Page(s) 1260193

    Abstract: Histiocytoses encompass a wide spectrum of diseases, all characterized by tissue infiltration by CD68+ histiocytes. Most adult histiocytoses are considered clonal diseases because they highlight recurrent somatic mutations in the MAP-kinase pathway gene, ...

    Abstract Histiocytoses encompass a wide spectrum of diseases, all characterized by tissue infiltration by CD68+ histiocytes. Most adult histiocytoses are considered clonal diseases because they highlight recurrent somatic mutations in the MAP-kinase pathway gene, primarily
    MeSH term(s) Adult ; Child ; Humans ; Erdheim-Chester Disease/genetics ; Histiocytosis, Langerhans-Cell/genetics ; Mutation ; Proto-Oncogene Proteins B-raf/genetics ; Retrospective Studies ; Histiocytosis/metabolism
    Chemical Substances BRAF protein, human (EC 2.7.11.1) ; Proto-Oncogene Proteins B-raf (EC 2.7.11.1)
    Language English
    Publishing date 2023-09-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1260193
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Increased neopterin in cerebrospinal fluid in active adult neurohistiocytosis.

    Razanamahery, Jerome / Samson, Maxime / Idbaih, Ahmed / Greigert, Helene / Comby, Pierre Olivier / Cohen Aubart, Fleur / Haroche, Julien / Audia, Sylvain / Bonnotte, Bernard

    Hematological oncology

    2023  Volume 41, Issue 4, Page(s) 762–767

    Abstract: Diagnosis of neuro-histiocytosis is challenging and relies on clinical presentation, imaging, and cerebrospinal fluid (CSF) analysis to exclude differential diagnoses. Brain biopsy remains the gold standard for accurate diagnosis, but it is rarely ... ...

    Abstract Diagnosis of neuro-histiocytosis is challenging and relies on clinical presentation, imaging, and cerebrospinal fluid (CSF) analysis to exclude differential diagnoses. Brain biopsy remains the gold standard for accurate diagnosis, but it is rarely performed because of the risk of the procedure and the low rentability in neurodegenerative presentation. Therefore, there is an unmet need to identify a specific biomarker for diagnosing neurohistiocytosis in adults. Because microglia (brain macrophages) is involved in the pathogenesis of neurohistiocytosis and produces neopterin secondary to aggression, the purpose of our study was to evaluate the value of the CSF neopterin levels for the diagnosis of active neurohistiocytosis. Of the 21 adult patients with histiocytosis, four patients had clinical symptoms compatible with neurohistiocytosis. In the two patients with a confirmed diagnosis of neurohistiocytosis, CSF neopterin levels were elevated as well as IL-6 and IL-10 levels. In contrast, the two other patients in whom the diagnosis of neurohistiocytosis was infirmed and all other patients with histiocytosis without active neurological disease involvement had normal CSF neopterin levels. In summary, increased CSF neopterin concentration represented a valuable tool for diagnosing active neuro-histiocytosis in adults with histiocytic neoplasms in this preliminary study.
    MeSH term(s) Humans ; Adult ; Neopterin/cerebrospinal fluid ; Biomarkers ; Brain ; Hematologic Neoplasms ; Histiocytosis
    Chemical Substances Neopterin (670-65-5) ; Biomarkers
    Language English
    Publishing date 2023-06-11
    Publishing country England
    Document type Case Reports
    ZDB-ID 604884-5
    ISSN 1099-1069 ; 0278-0232
    ISSN (online) 1099-1069
    ISSN 0278-0232
    DOI 10.1002/hon.3189
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1816: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Concurrent diagnosis of oropharynx cancer and bone sarcoidosis mimicking metastasis.

    Razanamahery, J / Caubet, M / Gassian, N / Echalier, C / Soumagne, T

    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique

    2020  Volume 25, Issue 1, Page(s) 51–54

    Abstract: Bone location is uncommon in both sarcoidosis and in neck cancer (HNC). Diagnosis of a bone lesion is therefore challenging to distinguish its nature in a patient suffering from both diseases. We report the case of a 69-years-old woman referred for P16 ... ...

    Abstract Bone location is uncommon in both sarcoidosis and in neck cancer (HNC). Diagnosis of a bone lesion is therefore challenging to distinguish its nature in a patient suffering from both diseases. We report the case of a 69-years-old woman referred for P16 positive HPV-HNC. Magnetic Resonance Imaging (MRI) showed T2 hypo-signal on iliac crest and spine.
    MeSH term(s) Adrenal Cortex Hormones/therapeutic use ; Aged ; Bone Diseases/diagnostic imaging ; Bone Diseases/drug therapy ; Chemoradiotherapy/methods ; Female ; Human papillomavirus 16 ; Humans ; Ilium/diagnostic imaging ; Immunosuppressive Agents/therapeutic use ; Magnetic Resonance Imaging ; Methotrexate/therapeutic use ; Oropharyngeal Neoplasms/diagnostic imaging ; Oropharyngeal Neoplasms/therapy ; Oropharyngeal Neoplasms/virology ; Sarcoidosis/diagnostic imaging ; Sarcoidosis/drug therapy ; Spinal Diseases/diagnostic imaging
    Chemical Substances Adrenal Cortex Hormones ; Immunosuppressive Agents ; Methotrexate (YL5FZ2Y5U1)
    Language English
    Publishing date 2020-12-26
    Publishing country France
    Document type Case Reports ; Journal Article
    ZDB-ID 1397169-4
    ISSN 1769-6658 ; 1278-3218
    ISSN (online) 1769-6658
    ISSN 1278-3218
    DOI 10.1016/j.canrad.2020.06.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4832: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 96: Show issues

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  4. Article ; Online: Malignant Atrophic Papulosis.

    Mareschal, Adrien / Razanamahery, Jérôme / Aubin, François

    JAMA dermatology

    2019  Volume 156, Issue 2, Page(s) 204

    MeSH term(s) Adult ; Humans ; Male ; Malignant Atrophic Papulosis/diagnosis ; Malignant Atrophic Papulosis/pathology ; Skin/pathology
    Language English
    Publishing date 2019-11-13
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2701761-8
    ISSN 2168-6084 ; 2168-6068
    ISSN (online) 2168-6084
    ISSN 2168-6068
    DOI 10.1001/jamadermatol.2019.3726
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui VI Zs.32: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: COVID-19 as a cause of immune thrombocytopenia.

    Humbert, S / Razanamahery, J / Payet-Revest, C / Bouiller, K / Chirouze, C

    Medecine et maladies infectieuses

    2020  Volume 50, Issue 5, Page(s) 459–460

    MeSH term(s) Adrenal Cortex Hormones/therapeutic use ; Aged, 80 and over ; Betacoronavirus/immunology ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/drug therapy ; Coronavirus Infections/immunology ; Coronavirus Infections/pathology ; Humans ; Male ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/immunology ; Pneumonia, Viral/pathology ; Prognosis ; Purpura, Thrombocytopenic, Idiopathic/diagnosis ; Purpura, Thrombocytopenic, Idiopathic/drug therapy ; Purpura, Thrombocytopenic, Idiopathic/etiology ; Purpura, Thrombocytopenic, Idiopathic/virology ; SARS-CoV-2 ; Seroconversion/physiology ; Severity of Illness Index ; Time-to-Treatment
    Chemical Substances Adrenal Cortex Hormones
    Keywords covid19
    Language English
    Publishing date 2020-05-20
    Publishing country France
    Document type Case Reports ; Letter
    ZDB-ID 423536-8
    ISSN 1769-6690 ; 0399-077X ; 1166-8237
    ISSN (online) 1769-6690
    ISSN 0399-077X ; 1166-8237
    DOI 10.1016/j.medmal.2020.05.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1410: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  6. Article ; Online: Specific blood monocyte distribution in histiocytoses correlates with vascular involvement and disease activity.

    Razanamahery, Jerome / Samson, Maxime / Guy, Julien / Racine, Jessica / Row, Celine / Greigert, Hélène / Nicolas, Barbara / Francois, Stephanie / Emile, Jean-François / Cohen-Aubart, Fleur / Audia, Sylvain / Haroche, Julien / Bonnotte, Bernard

    Haematologica

    2023  Volume 108, Issue 12, Page(s) 3444–3448

    MeSH term(s) Humans ; Monocytes ; Histiocytosis
    Language English
    Publishing date 2023-12-01
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2333-4
    ISSN 1592-8721 ; 0017-6567 ; 0390-6078
    ISSN (online) 1592-8721
    ISSN 0017-6567 ; 0390-6078
    DOI 10.3324/haematol.2023.282739
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh III Zs.76: Show issues Location:
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  7. Article: Tropheryma Whipplei infection mimicking giant cell arteritis flare in a patient treated with interleukin-6 receptor blocker tocilizumab.

    Razanamahery, Jerome / Humbert, Sebastien / Gil, Helder / Bouiller, Kevin / Magy-Bertrand, Nadine

    Clinical and experimental rheumatology

    2020  Volume 38 Suppl 124, Issue 2, Page(s) 245–246

    MeSH term(s) Antibodies, Monoclonal, Humanized/adverse effects ; Diagnosis, Differential ; Giant Cell Arteritis ; Humans ; Receptors, Interleukin-6/antagonists & inhibitors ; Tropheryma ; Whipple Disease/diagnosis
    Chemical Substances Antibodies, Monoclonal, Humanized ; Receptors, Interleukin-6 ; tocilizumab (I031V2H011)
    Language English
    Publishing date 2020-04-10
    Publishing country Italy
    Document type Case Reports ; Letter
    ZDB-ID 605886-3
    ISSN 1593-098X ; 0392-856X
    ISSN (online) 1593-098X
    ISSN 0392-856X
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    Zs.A 2002: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  8. Article ; Online: A Rare Case of Chylous Ascites.

    Razanamahery, Jérôme / Jacquier, Anthony / Humbert, Sébastien

    Gastroenterology

    2017  Volume 153, Issue 4, Page(s) 903–905

    Language English
    Publishing date 2017-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2017.04.008
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    Ui V Zs.44: Show issues Location:
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    Zs.MO 572: Show issues

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  9. Article: Immune Thrombocytopenia Revealing Enriched IgG-4 Peri-Renal Rosai-Dorfman Disease Successfully Treated with Rituximab: A Case Report and Literature Review.

    Razanamahery, Jerome / Humbert, Sebastien / Emile, Jean-Francois / Cohen-Aubart, Fleur / Fontan, Jean / Maksud, Philippe / Audia, Sylvain / Haroche, Julien

    Frontiers in medicine

    2021  Volume 8, Page(s) 678456

    Abstract: Immune thrombocytopenia (ITP) is a rare autoimmune-mediated condition characterized by isolated thrombocytopenia (<100 G/L) after exclusion of other causes. Mostly primary, it is associated with hematological malignancy, autoimmune disorders, or ... ...

    Abstract Immune thrombocytopenia (ITP) is a rare autoimmune-mediated condition characterized by isolated thrombocytopenia (<100 G/L) after exclusion of other causes. Mostly primary, it is associated with hematological malignancy, autoimmune disorders, or infection in 20% of patients. It is exceptionally described in patients with histiocytosis, mostly in children (seven patients in literature). We report a case of a 69-year-old man with ITP leading to the diagnosis of histiocytosis. At ITP's diagnosis, the patient had elevated gamma-globulins leading to computed tomography showing bilateral peri-renal infiltration. The biopsy showed enriched IgG-4 peri-renal Rosai Dorfman disease with
    Language English
    Publishing date 2021-06-16
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2021.678456
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Characteristics of Adult Patients with Idiopathic Retroperitoneal Fibrosis and Assessment of Risk of Relapse at Diagnosis.

    Razanamahery, Jerome / Bouldoires, Bastien / Humbert, Sebastien / Bielefeld, Philip / Fournier, Veronique / Bonnotte, Bernard / Blaison, Gilles / Magy-Bertrand, Nadine

    Journal of clinical medicine

    2021  Volume 10, Issue 7

    Abstract: Objectives: To compare adult patients' characteristics suffering from idiopathic retroperitoneal fibrosis between "relapse-free" and relapsing patients at the diagnosis and identify factors associated with relapse at initial presentation.: Methods: ... ...

    Abstract Objectives: To compare adult patients' characteristics suffering from idiopathic retroperitoneal fibrosis between "relapse-free" and relapsing patients at the diagnosis and identify factors associated with relapse at initial presentation.
    Methods: We conducted a retrospective multicentric study in four hospitals in Eastern France, from 1993 to 2020, of adult patients suffering from idiopathic retroperitoneal fibrosis. We analyzed clinical, biological, and radiological features at diagnosis and during a forty-month follow-up.
    Results: Of 47 patients suffering from retroperitoneal fibrosis, 21 patients had idiopathic retroperitoneal fibrosis. Among them, 13 experienced one or more relapses during follow-up. At diagnosis, clinical characteristics, relevant comorbidities, biological and radiological features were similar between groups. Smoking cessation seems associated with decreased relapse risk (
    Conclusion: No clinical, biological, or radiological features could predict relapse at retroperitoneal fibrosis diagnosis, but smoking cessation may prevent relapse.
    Language English
    Publishing date 2021-03-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm10071380
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