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Article ; Online: The effect of systemic inflammatory index and systemic inflammatory response index on success of varicoselectomy.

Erdogan, Omer / Ok, Fesih

2023 Volume 91, Issue 1, Page(s) 170–175

Abstract: Background: Varicocele is the most common correctable cause of male infertility. The treatment of varicocele is surgery. However, which patients will benefit from the surgery is controversial. Our aims to investigate the effect of systemic immune- ... ...

Abstract	Background: Varicocele is the most common correctable cause of male infertility. The treatment of varicocele is surgery. However, which patients will benefit from the surgery is controversial. Our aims to investigate the effect of systemic immune-inflammation index (SII) and systemic inflammatory response index (SIRI) on varicocelectomy success. Methods: Patients who underwent varicocelectomy in our clinic between January 2016 and June 2022 were analyzed retrospectively. Varicocelectomy success was defined as >50% increase in post-operative total motile sperm count (TMSC) in those with pre- operative TMSC > 5 million and at least 100% increase in those with <5 million. The patients were divided into two groups as benefiting from the treatment (Group 1) and no benefits (Group 2). Results: Of the 207 patients who underwent varicocelectomy, 144 (69.6%) of them improved their semen parameters, and 63 (30.4%) did not. The optimum cut-off value of SII was 334.6, with an AUC of 0.733 (95% CI: 0.665-0.813). The best cut-off value for SIRI of 0.882, with an AUC of 0.692 (95% CI: 0.607-0.772). The highest sensitivity and specificity were 0.692 and 0.601 ( Conclusions: Our results showed that preoperative SII and SIRI values were lower in infertile patients who underwent successful varicocelectomy. Therefore, we think that these parameters will be useful in identifying patients who will benefit before varicocelectomy.
MeSH term(s)	Humans ; Male ; Varicocele/complications ; Retrospective Studies ; Semen ; Infertility, Male ; Systemic Inflammatory Response Syndrome/complications
Language	English
Publishing date	2023-08-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	204043-8
ISSN	1724-6075 ; 0376-0057 ; 0391-5603
ISSN (online)	1724-6075
ISSN	0376-0057 ; 0391-5603
DOI	10.1177/03915603231192739
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Article ; Online: Could Penile Mondor's Disease Worsen Symptoms in Patients with Erectile Dysfunction?

Durmus, Emrullah / Ok, Fesih

Journal of investigative surgery : the official journal of the Academy of Surgical Research

2022 Volume 35, Issue 8, Page(s) 1668–1672

Abstract: Background: To determine the impact of Penile Mondor's disease (PMD) in patients with erectile dysfunction (ED).: Methods: Forty-seven patients diagnosed with PMD were included in the study and analyzed prospectively. The patients were divided into ... ...

Abstract	Background: To determine the impact of Penile Mondor's disease (PMD) in patients with erectile dysfunction (ED). Methods: Forty-seven patients diagnosed with PMD were included in the study and analyzed prospectively. The patients were divided into two groups according to the presence of ED at admission. The patients with ED were named Group 1, and those without ED were named Group 2. The International Index of Erectile Function (IIEF-5) and Beck Anxiety Inventory (BAI) forms at admission, 3rd, and 6th months were compared. Results: There were 21 (44.6%) patients in Group 1 and 26 (55.4%) patients in Group 2. The mean patient ages in Group 1 and Group 2 were 38.1 ± 7.5 and 26.9 ± 10.3 years, respectively ( Conclusion: PMD can worsen symptoms in men with ED who have a low IIEF5 score. The anxiety of recurrence of PMD during sexual intercourse may have caused this situation, or this may also be due to the natural progression of ED.
MeSH term(s)	Adult ; Erectile Dysfunction/diagnosis ; Erectile Dysfunction/epidemiology ; Erectile Dysfunction/etiology ; Humans ; Male ; Middle Aged ; Penile Erection
Language	English
Publishing date	2022-06-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	639444-9
ISSN	1521-0553 ; 0894-1939
ISSN (online)	1521-0553
ISSN	0894-1939
DOI	10.1080/08941939.2022.2092664
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Article ; Online: Comparative analysis of ureteroscopic laser lithotripsy and extracorporeal shock wave lithotripsy in the treatment of childhood proximal ureteral stones.

Durmus, Emrullah / Ok, Fesih

Pediatric surgery international

2022 Volume 39, Issue 1, Page(s) 62

Abstract: Purpose: This study aims to make a comparative analysis of the superiority of ESWL and URS in proximal ureteral stones in children.: Methods: A total of 155 patients under the age of 15 were included in the study. The patients were divided into two ... ...

Abstract	Purpose: This study aims to make a comparative analysis of the superiority of ESWL and URS in proximal ureteral stones in children. Methods: A total of 155 patients under the age of 15 were included in the study. The patients were divided into two groups as Group 1 (n = 80, ESWL) and Group 2 (n = 75, URS) according to the type of procedure performed. The patients in both groups were evaluated in terms of age, gender, lateralization, stone size, stone volüme, stone density, and preoperative hydronephrosis. In addition, both methods used were compared in terms of success rate, time, cost, hospitalization and complications. Results: The mean age were 7.4 ± 2.1 in Group-1 and 8.1 ± 1.8 in Group-2. Demographic, clinical and laboratory data of both groups were similar. The hospitalization time, procedure time, success rate and cost were significantly higher in Group-2. The complication rate was significantly higher in Group-2 (p < 0.001). There was a significant negative correlation between ESWL success and stone volume (ρ - 0.375, p = 0.001) and stone density (ρ - 0.283, p = 0.011). Conclusion: ESWL can be performed as the first line treatment of proximal ureteral stones in children due to its daily use, low cost, short procedure time and low complication rate. Increasing stone volume and density reduces the success of ESWL.
MeSH term(s)	Child ; Humans ; Lithotripsy, Laser ; Ureteroscopy/methods ; Retrospective Studies ; Lithotripsy/methods ; Ureteral Calculi/therapy ; Treatment Outcome
Language	English
Publishing date	2022-12-24
Publishing country	Germany
Document type	Journal Article
ZDB-ID	632773-4
ISSN	1437-9813 ; 0179-0358
ISSN (online)	1437-9813
ISSN	0179-0358
DOI	10.1007/s00383-022-05349-y
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Article ; Online: Disease management in a patient diagnosed with COVID-19 disease during induction intravesical BCG therapy: A case report and review of the literature.

Ok, Fesih / Durmus, Emrullah

Urologia

2021 Volume 90, Issue 1, Page(s) 195–197

Abstract: Objective: To discuss the patient diagnosed with COVID-19 disease while receiving intravesical induction bacillus Calmette-Guérin (BCG) treatment for non-muscle-invasive bladder cancer, its management in the light of the literature.: Patient and ... ...

Abstract	Objective: To discuss the patient diagnosed with COVID-19 disease while receiving intravesical induction bacillus Calmette-Guérin (BCG) treatment for non-muscle-invasive bladder cancer, its management in the light of the literature. Patient and methods: A 52-year-old male patient, who received intravesical BCG treatment for high-grade pT1 papillary urothelial carcinoma, presented 12 h after taking the fourth dose of induction therapy 38.2° fever and chills. The patient's reverse transcriptase-polymerase chain reaction test was positive, and Thorax CT imaging showed a few ground-glass pneumonic infiltrations in bilateral lung bases consistent with COVID-19 disease. Results: Although international urology associations have current recommendations regarding the pandemic process, only one study has made specific recommendations regarding the patient group diagnosed with COVID-19 while receiving intravesical BCG treatment. According to this recommendation, we interrupted our patient's BCG treatment for 3 weeks and then completed the treatment for 6 weeks. A maintenance treatment not exceeding 1 year was planned. Conclusion: This group of patients' recommendation is to delay BCG therapy for at least 3 weeks after initial symptoms to allow for complete recovery. Although the administration schedule varies, maintenance therapy is recommended for no more than 1 year.
MeSH term(s)	Humans ; Male ; Middle Aged ; Adjuvants, Immunologic/therapeutic use ; Administration, Intravesical ; BCG Vaccine/therapeutic use ; Carcinoma, Transitional Cell/drug therapy ; Carcinoma, Transitional Cell/pathology ; COVID-19/diagnosis ; Disease Management ; Neoplasm Invasiveness ; Neoplasm Recurrence, Local ; Urinary Bladder Neoplasms/drug therapy ; Urinary Bladder Neoplasms/pathology
Chemical Substances	Adjuvants, Immunologic ; BCG Vaccine
Language	English
Publishing date	2021-03-12
Publishing country	United States
Document type	Review ; Case Reports ; Journal Article
ZDB-ID	204043-8
ISSN	1724-6075 ; 0376-0057 ; 0391-5603
ISSN (online)	1724-6075
ISSN	0376-0057 ; 0391-5603
DOI	10.1177/03915603211001670
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Article ; Online: Flank Pain as a Symptom of COVID-19.

Durmus, Emrullah / Ok, Fesih

Urology

2020 Volume 148, Page(s) e13–e14

Abstract: The COVID-19 disease is spreading rapidly worldwide, and no vaccine or very effective drug has been found yet. However, the transmission rate of the disease can be reduced by taking precautions. Therefore, it is essential to detect the patients early to ... ...

Abstract	The COVID-19 disease is spreading rapidly worldwide, and no vaccine or very effective drug has been found yet. However, the transmission rate of the disease can be reduced by taking precautions. Therefore, it is essential to detect the patients early to prevent the spread of the disease.
MeSH term(s)	Adult ; COVID-19/diagnosis ; Flank Pain/etiology ; Humans ; Lung/diagnostic imaging ; Male ; Tomography, X-Ray Computed
Keywords	covid19
Language	English
Publishing date	2020-11-17
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	192062-5
ISSN	1527-9995 ; 0090-4295
ISSN (online)	1527-9995
ISSN	0090-4295
DOI	10.1016/j.urology.2020.11.007
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Article ; Online: The role of the resistive index in predicting testicular atrophy after orchiopexy in unilateral undescended testis.

Ok, Fesih / Durmus, Emrullah / Ayaz, Muzaffer

Pediatric surgery international

2022 Volume 39, Issue 1, Page(s) 38

Abstract: Purpose: One of the most important complications of undescended testis (UDT) surgery is testicular atrophy (TA). We aimed to investigate the factors associated with TA in children who underwent orchiopexy for unilateral UDT.: Methods: The data of 215 ...

Abstract	Purpose: One of the most important complications of undescended testis (UDT) surgery is testicular atrophy (TA). We aimed to investigate the factors associated with TA in children who underwent orchiopexy for unilateral UDT. Methods: The data of 215 patients aged < 15 years who underwent orchiopexy for unilateral UDT between November 2019 and September 2022 were analyzed retrospectively. Clinical, radiological, surgical, and follow-up findings were recorded. Results: TA was observed in 29 (13.5%) patients. Mean resistive index (RI) values were 0.44 ± 0.06, 0.54 ± 0.09 and 0.69 ± 0.1 in low, middle and high testicular locations, respectively, and intratesticular RI increased significantly as the testis location raised (p < 0.001). After orchiopexy, the mean testis volume ratio (TVR) increased significantly (0.63 ± 0.13 vs. 0.77 ± 0.15, p < 0.001). Besides, the mean RI values decreased significantly in the postoperative follow-up (0.53 ± 0.12 vs. 0.47 ± 0.13, p < 0.001). In multivariate regression analysis, testicular high location (OR 4.332, 95% CI 2.244-6.578, p = 0.002), deferens-epididymal anomaly (OR 3.134, 95% CI 1.345-7.146, p = 0.021), TVR ≤ 0.5 (OR 5.679, 95% CI 2.953-12.892, p < 0.001) and RI ≥ 0.6 (OR 7.158, 95% CI 3.936-14.569, p < 0.001) were independent predictive factors for TA after orchiopexy. Conclusion: Higher testis location, deferens-epididymis anomaly, preoperative TVR and RI were independent predictive factors for TA after orchiopexy in unilateral UDT. The results of the study will help surgeons to predict TA before orchiopexy.
MeSH term(s)	Child ; Male ; Humans ; Cryptorchidism/diagnostic imaging ; Cryptorchidism/surgery ; Retrospective Studies ; Atrophy
Language	English
Publishing date	2022-12-08
Publishing country	Germany
Document type	Journal Article
ZDB-ID	632773-4
ISSN	1437-9813 ; 0179-0358
ISSN (online)	1437-9813
ISSN	0179-0358
DOI	10.1007/s00383-022-05336-3
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Article ; Online: Flank pain as a symptom of COVID-19

Durmus, Emrullah / Ok, Fesih

Urology ; ISSN 0090-4295

2020

Keywords	Urology ; covid19
Language	English
Publisher	Elsevier BV
Publishing country	us
Document type	Article ; Online
DOI	10.1016/j.urology.2020.11.007
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Extraprostatic extension in multiparametric MRI; Is presurgical detection possible?

Ayaz, Muzaffer / Gülseren, Yıldız / İnan, İbrahim / Ok, Fesih / Kabaalioğlu, Adnan / Yıldırım, Asıf

Journal of cancer research and therapeutics

2023 Volume 19, Issue Suppl 2, Page(s) S639–S644

Abstract: Introduction: Extraprostatic extension (EPE) is one of the important factors affecting the prognosis of prostate cancer (PCa). Therefore, preoperative evaluation of the presence of EPE is essential in multiparametric magnetic resonance imaging (mpMRI) ... ...

Abstract	Introduction: Extraprostatic extension (EPE) is one of the important factors affecting the prognosis of prostate cancer (PCa). Therefore, preoperative evaluation of the presence of EPE is essential in multiparametric magnetic resonance imaging (mpMRI) examination. However, for the evaluation of mpMRI, objective criteria are needed to detect EPE, especially microscopic EPE. Aim: To evaluate the efficacy of 1.5T MRI using lesion length (LL) and tumor-capsule contact length (TCL) in detecting EPE in PCa. Methods: A total of 110 patients who underwent radical prostatectomy due to PCa were enrolled. Preoperative MR images were evaluated retrospectively by two independent observers who did not know the histopathological results. The observers evaluated LL and TCL. The radiological findings, including lesion location, were verified using histopathological mapping. Results: Multiparametric MRI examination of the prostate demonstrated low sensitivity (Observer 1; 40.4% and Observer 2; 40.4%) but high specificity (Observer 1; 96.6% and Observer 2; 84.5%), with significant differences for detecting EPE (Observer 1, P < 0.0001; Observer 2, P = 0.003). The increased PI-RADS score correlated positively with the increased EPE rate (P < 0.0001 for both observers). The mean LL and TCL values were statistically significantly higher in patients with EPE than in patients without EPE. The TCL was a significant parameter for EPE, with high sensitivity and low for both observers. For both observes the cutoff value of LL for EPE was 14.5 mm, and the cutoff value of TCL for EPE was 9.5 mm. Histopathological LL value (28 ± 12,3 mm) was higher than radiological LLs (Observer 1; 22,14 ± 10,15 mm and Observer 2; 19,06 ± 8,61). Conclusion: The results revealed that 1.5T MRI demonstrated low sensitivity and high specificity in detecting EPE. The LL and TCL may be indirectly beneficial in detecting EPE. Considering the radiological underestimation of LL may be helpful before PCa surgery.
MeSH term(s)	Male ; Humans ; Multiparametric Magnetic Resonance Imaging ; Magnetic Resonance Imaging/methods ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms/surgery ; Retrospective Studies ; Prostate/diagnostic imaging ; Prostate/surgery ; Prostate/pathology ; Prostatectomy
Language	English
Publishing date	2023-04-28
Publishing country	India
Document type	Journal Article
ZDB-ID	2187633-2
ISSN	1998-4138 ; 0973-1482
ISSN (online)	1998-4138
ISSN	0973-1482
DOI	10.4103/jcrt.jcrt_1253_22
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Article: Flank pain as a symptom of COVID-19

Durmus, Emrullah Ok Fesih

Urology

Abstract: The COVID-19 disease is spreading rapidly worldwide, and no vaccine or very effective drug has been found yet However, the transmission rate of the disease can be reduced by taking precautions Therefore, it is essential to detect the patients early to ... ...

Abstract	The COVID-19 disease is spreading rapidly worldwide, and no vaccine or very effective drug has been found yet However, the transmission rate of the disease can be reduced by taking precautions Therefore, it is essential to detect the patients early to prevent the spread of the disease 1,2 We report a case of 26 year old male patient who was admitted to our urology outpatient clinic with the complaint of flank pain and had incidental findings of COVID-19 in the lung bases on abdominal CT
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #927417
Database	COVID19

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Article ; Online: Could flank pain be an indicator of COVID-19 infection?

Durmus, Emrullah / Ok, Fesih / Erdogan, Ömer / Saglik, Semih

Malawi medical journal : the journal of Medical Association of Malawi

2021 Volume 32, Issue 4, Page(s) 192–196

Abstract: Background: We describe the incidental detection of patients infiltrates due to COVID-19 in lung basal sections in patients undergoing abdominal computed tomography (CT) with flank pain attending the urology outpatient clinic during the current pandemic. ...

Abstract	Background: We describe the incidental detection of patients infiltrates due to COVID-19 in lung basal sections in patients undergoing abdominal computed tomography (CT) with flank pain attending the urology outpatient clinic during the current pandemic. Methods: We retrospectively analysed 276 patients admitted to the Siirt Training and Research Hospital Urology outpatients clinic between 15 March 2020 and 9 August 2020 with a complaint of flank pain and undergoing non-contrast abdominal CT. A total of 10 patients with COVID-19 compatible findings in CT were defined as the study group. A control group was formed from 10 patients with only urological pathologies (kidney stones, ureteral stones, and hydronephrosis) without a COVID-19 compatible appearance on CT. Results: Ten (3.6 %) patients were identified with COVID-19 and pneumonic infiltrations in the basal regions of the lungs; diagnosis was made by cross-sectional abdominal CT. The visual analog scale (VAS) score of flank pain was significantly higher in the control group (p<0.001); these subjects had urological pathology and no evidence of COVID-19 in the basal regions of the lungs on abdominal CT. There were no signs of COVID-19 disease detected during the admissions procedure in the urology outpatient clinic, including fever, cough, and shortness of breath. Conclusion: During the COVID-19 pandemic, it is important to consider a diagnosis of COVID_19 in patients reporting non-severe flank pain if no urological pathology is evident on abdominal CT scans.
MeSH term(s)	Abdomen/diagnostic imaging ; Adult ; COVID-19/diagnosis ; COVID-19 Nucleic Acid Testing ; Cohort Studies ; Flank Pain/etiology ; Humans ; Incidental Findings ; Lung/diagnostic imaging ; Male ; Middle Aged ; Pandemics ; SARS-CoV-2/genetics ; SARS-CoV-2/isolation & purification ; Tomography, X-Ray Computed/methods
Language	English
Publishing date	2021-05-17
Publishing country	Malawi
Document type	Journal Article
ISSN	1995-7270 ; 1995-7262
ISSN (online)	1995-7270
ISSN	1995-7262
DOI	10.4314/mmj.v32i4.3
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