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Article ; Online: The Effects of

Sara, Meutia / Ilyas, Faridha / Hasballah, Kartini / Nurjannah, Nurjannah / Mudatsir, Mudatsir

2023 Volume 59, Issue 11

Abstract: Background and ... ...

Abstract	Background and Objectives
MeSH term(s)	Child ; Humans ; Animals ; Dermatitis, Atopic/drug therapy ; Staphylococcus aureus ; Oligochaeta ; Staphylococcal Infections ; Interleukins ; Fluocinolone Acetonide/pharmacology ; Fluocinolone Acetonide/therapeutic use ; Severity of Illness Index
Chemical Substances	Interleukins ; Fluocinolone Acetonide (0CD5FD6S2M)
Language	English
Publishing date	2023-11-15
Publishing country	Switzerland
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	2188113-3
ISSN	1648-9144 ; 1010-660X
ISSN (online)	1648-9144
ISSN	1010-660X
DOI	10.3390/medicina59112007
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Probing antibacterial drugs for

Saputri, Dewi / Mubarak, Zaki / Mudatsir, Mudatsir / Setyawati, Inda / Setiawan, Aprijal Ghiyas / Abrar, Mahdi

Journal of advanced pharmaceutical technology & research

2023 Volume 14, Issue 3, Page(s) 196–201

Abstract: Fusobacterium ... ...

Abstract	Fusobacterium nucleatum
Language	English
Publishing date	2023-07-28
Publishing country	India
Document type	Journal Article
ISSN	2231-4040
ISSN	2231-4040
DOI	10.4103/JAPTR.JAPTR_129_23
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Antibacterial and anti-inflammatory activities of

Sriyanti, Cut / Siregar, Tongku N / Mudatsir, Mudatsir / Gani, Azhari / Hasan, Denny I / Sutriana, Amalia

Narra J

2023 Volume 3, Issue 2, Page(s) e176

Abstract: Inappropriate and prolonged administration of antibiotics in mastitis could cause resistance and herbal treatment might could be one alternative treatment. ...

Abstract	Inappropriate and prolonged administration of antibiotics in mastitis could cause resistance and herbal treatment might could be one alternative treatment.
Language	English
Publishing date	2023-07-12
Publishing country	Indonesia
Document type	Journal Article
ISSN	2807-2618
ISSN (online)	2807-2618
DOI	10.52225/narra.v3i2.176
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Gallbladder perforation: A rare case report.

Warsinggih / Mudatsir / Arsyad, Arham / Faruk, Muhammad

International journal of surgery case reports

2023 Volume 104, Page(s) 107927

Abstract: Introduction: Gallbladder perforation (GBP) is a rare but severe, often fatal, disease due to its delayed pathology, demanding urgent surgical intervention. GBP can result from acute cholecystitis in 6-12 % of cases. It manifests in a variety of ... ...

Abstract	Introduction: Gallbladder perforation (GBP) is a rare but severe, often fatal, disease due to its delayed pathology, demanding urgent surgical intervention. GBP can result from acute cholecystitis in 6-12 % of cases. It manifests in a variety of presentations. The diagnosis is frequently postponed or missed. Case presentation: A 68-year-old woman came to the emergency department with the chief complaint of abdominal pain for 1 week. The pain began in the epigastric region and right upper abdominal quadrant, then extended to the whole abdomen. Abdominal bowel sounds were decreased, with muscular defense and tenderness throughout the abdomen. On rectal touch examination, the sphincter was loose. Laboratory tests found leukocytosis and hyperglycemia. An abdominal ultrasound examination showed cholelithiasis, sludge, and little echo fluid in the lower right abdomen. Clinical discussion: The patient was diagnosed with generalized peritonitis and cholelithiasis with sepsis (qSOFA score 2; SOFA score 2). An emergency exploratory laparotomy was performed. We found gallbladder (GB) dilatation with fibrin surrounding the GB wall and a perforation in the border of the GB neck and cystic duct of around 10 mm in diameter. We performed cholecystectomy in the distal region of perforation. Antibiotics and analgesics were used. The patient was discharged on postoperative day 5. After 4 weeks, she was followed up and doing well with no complaints. Conclusion: Early diagnosis and treatment are essential for GBP to prevent morbidity and mortality. Initial management is required; in patients with acute abdominal pain, the surgeon should suspect the cause may be GBP.
Language	English
Publishing date	2023-02-11
Publishing country	Netherlands
Document type	Case Reports
ISSN	2210-2612
ISSN	2210-2612
DOI	10.1016/j.ijscr.2023.107927
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Risk factors of MDR-TB and impacts of COVID-19 pandemic on escalating of MDR-TB incidence in lower-middle-income countries: A scoping review.

Ichsan, Ichsan / Redwood-Campbell, Lynda / Mahmud, Nissa N / Dimiati, Herlina / Yani, Muhammad / Mudatsir, Mudatsir / Syukri, Maimun

Narra J

2023 Volume 3, Issue 2, Page(s) e220

Abstract: The coronavirus disease 2019 (COVID-19) pandemic is affecting tuberculosis (TB) treatment in many ways that might lead to increasing the prevalence of multi-drugs-resistance tuberculosis (MDR-TB), especially in lower-middle-income-countries (LMICs). This ...

Abstract	The coronavirus disease 2019 (COVID-19) pandemic is affecting tuberculosis (TB) treatment in many ways that might lead to increasing the prevalence of multi-drugs-resistance tuberculosis (MDR-TB), especially in lower-middle-income-countries (LMICs). This scoping review aimed to identify the risk factors of MDR-TB and to determine the impacts of the COVID-19 pandemic on MDR-TB prevalence in LMICs. This study was reported according to the preferred reporting items for systematic reviews and meta-analyses extension for scoping reviews (PRISMA-ScR) guideline. The relevant keywords were used to search studies in three databases (PubMed, ScienceDirect and SpringerLink) to identify the related articles. The English-written articles published from January 2012 to December 2022 that explored risk factors or causes of MDR-TB in LMICs were included. Out of 1,542 identified articles, 17 retrospective, prospective, case-control and cross-sectional studies from ten LMICs met were included in this scoping review. Twenty-one risk factors were discovered, with prior TB treatment (relapsed cases), diabetes, living area, living condition, smoking and low socioeconomic status were the main factors in developing MDR-TB during COVID-19 pandemic. The pandemic increased the MDR-TB prevalence through drug resistance transmission inside households, the distance between home and healthcare facilities and low socioeconomic status. This scoping review demonstrates how the COVID-19 pandemic has affected the rising incidence of MDR-TB in LMICs.
Language	English
Publishing date	2023-08-31
Publishing country	Indonesia
Document type	Journal Article
ISSN	2807-2618
ISSN (online)	2807-2618
DOI	10.52225/narra.v3i2.220
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Article ; Online: Quantity of antibiotic use and its association with clinical outcomes in COVID-19 patients: A snapshot from a provincial referral hospital in Indonesia.

Yossadania, Asyriva / Hayati, Zinatul / Harapan, Harapan / Saputra, Irwan / Mudatsir / Diah, Muhammad / Ramadhana, Ika F

Narra J

2023 Volume 3, Issue 3, Page(s) e272

Abstract: Irrational antibiotic use in Indonesia is considered high, yet there are still lacks reliable information regarding the issue. The quantity of antibiotic use studies, in particular during coronavirus disease 2019 (COVID-19) pandemic, was not well ... ...

Abstract	Irrational antibiotic use in Indonesia is considered high, yet there are still lacks reliable information regarding the issue. The quantity of antibiotic use studies, in particular during coronavirus disease 2019 (COVID-19) pandemic, was not well reported. The aim of this study was to evaluate antibiotic use in COVID-19 patients at a province referral hospital in Aceh, Indonesia, Dr Zainoel Abidin Hospital, and to assess the association between antibiotic use and COVID-19 clinical outcomes. The defined daily dose (DDD) method was used and expressed in DDDs per 100 patient-days as in hospital setting. The data were obtained from inpatient confirmed COVID-19 patients between March 2020 and December 2021. A logistic regression was used to determine the association between patients' characteristics and antibiotic usage with clinical outcomes. A total of 361 treated COVID-19 patients were included using a random sampling technique and analyzed. Out of 361 patients, 89.2% of them were treated with antibiotic(s). All the antibiotics were given empirically except for cefazoline (5.5%) that was used as prophylaxis to obstetric patients who underwent the c-section. Azithromycin was the most prescribed antibiotic and levofloxacin had the highest DDD. Our data suggested that there was no association between antibiotic use and clinical outcomes of COVID-19 patients (
Language	English
Publishing date	2023-12-25
Publishing country	Indonesia
Document type	Journal Article
ISSN	2807-2618
ISSN (online)	2807-2618
DOI	10.52225/narra.v3i3.272
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Article ; Online: Remdesivir and its antiviral activity against COVID-19

Andri Frediansyah / Firzan Nainu / Kuldeep Dhama / Mudatsir Mudatsir / Harapan Harapan

Clinical Epidemiology and Global Health, Vol 9, Iss , Pp 123-

A systematic review

2021 Volume 127

Abstract: Background: The aim of this study was to summarize the antiviral activities of remdesivir against SARS-CoV-2, the causative agent of COVID-19. Methods: Available publications were systematically explored on some databases and gray literature was examined. ...

Abstract	Background: The aim of this study was to summarize the antiviral activities of remdesivir against SARS-CoV-2, the causative agent of COVID-19. Methods: Available publications were systematically explored on some databases and gray literature was examined. Publications were discussed narratively. Results: Remdesivir inhibits SARS-CoV-2 replication, reduces viral load, and exerts protective effects in SARS-CoV-2 infected animals. Remdesivir also reduces the pathological process, alleviates mild symptoms, and improves pulmonary lesions in SARS-CoV-2-infecetd animals. Remdesivir has been used as a compassionate drug for treating COVID-19 patients. Conclusion: Although remdesivir has shown potent antiviral activities, more efficacy assessments are urgently warranted in clinical trials.
Keywords	COVID-19 ; SARS-CoV-2 ; Treatment ; Remdesivir ; Clinical trial ; Public aspects of medicine ; RA1-1270
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Remdesivir and its antiviral activity against COVID-19: A systematic review.

Frediansyah, Andri / Nainu, Firzan / Dhama, Kuldeep / Mudatsir, Mudatsir / Harapan, Harapan

Clinical epidemiology and global health

2020 Volume 9, Page(s) 123–127

Abstract: Background: The aim of this study was to summarize the antiviral activities of remdesivir against SARS-CoV-2, the causative agent of COVID-19.: Methods: Available publications were systematically explored on some databases and gray literature was ... ...

Abstract	Background: The aim of this study was to summarize the antiviral activities of remdesivir against SARS-CoV-2, the causative agent of COVID-19. Methods: Available publications were systematically explored on some databases and gray literature was examined. Publications were discussed narratively. Results: Remdesivir inhibits SARS-CoV-2 replication, reduces viral load, and exerts protective effects in SARS-CoV-2 infected animals. Remdesivir also reduces the pathological process, alleviates mild symptoms, and improves pulmonary lesions in SARS-CoV-2-infecetd animals. Remdesivir has been used as a compassionate drug for treating COVID-19 patients. Conclusion: Although remdesivir has shown potent antiviral activities, more efficacy assessments are urgently warranted in clinical trials.
Keywords	covid19
Language	English
Publishing date	2020-08-07
Publishing country	India
Document type	Journal Article ; Review
ISSN	2452-0918
ISSN	2452-0918
DOI	10.1016/j.cegh.2020.07.011
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Waning anti-SARS-CoV-2 receptor-binding domain total antibody in CoronaVac-vaccinated individuals in Indonesia.

Harapan, Harapan / Ar Royan, Hibban / Tyas, Islam Ing / Nadira, Auda / Abdi, Irham Faraby / Anwar, Samsul / Husnah, Milda / Ichsan, Ichsan / Pranata, Agung / Mudatsir, Mudatsir / Syukri, Maimun / Rizal, Samsul / Razali / Hamdani / Kurniawan, Rudi / Irwansyah, Irwansyah / Sofyan, Sarwo Edhy

F1000Research

2023 Volume 11, Page(s) 300

Abstract: ... ...

Abstract	Background
MeSH term(s)	Humans ; COVID-19 Vaccines ; Indonesia ; Cross-Sectional Studies ; COVID-19/prevention & control ; SARS-CoV-2 ; Antibodies, Viral
Chemical Substances	sinovac COVID-19 vaccine ; COVID-19 Vaccines ; Antibodies, Viral
Language	English
Publishing date	2023-04-12
Publishing country	England
Document type	Journal Article
ZDB-ID	2699932-8
ISSN	2046-1402 ; 2046-1402
ISSN (online)	2046-1402
ISSN	2046-1402
DOI	10.12688/f1000research.109676.2
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Article ; Online: Penerapan Handout Berbasis Pendekatan Sets (Science, Environment, Technology, And Society) pada Materi Bioteknologi Terhadap Hasil Belajar Siswa MAS Darul Ihsan Aceh Besar

Eliyanti Eliyanti / Hasanuddin Hasanuddin / Mudatsir Mudatsir

Biotik: Jurnal Ilmiah Biologi Teknologi dan Kependidikan, Vol 6, Iss 2, Pp 105-

2019 Volume 109

Abstract: A research to investigate the improvement of student learning outcomes on Biotechnology concept with the application of SETS (Science, Environment, Technology and Society) based handout has been carried out at MAS DarulIhsan Aceh Besar on the second ... ...

Abstract	A research to investigate the improvement of student learning outcomes on Biotechnology concept with the application of SETS (Science, Environment, Technology and Society) based handout has been carried out at MAS DarulIhsan Aceh Besar on the second semester of the Academic Year 2017/2018. The research used The Pre-experimental with One Group Pretest-Posttest Design. The samples were 32 students of class XII/b MAS Darul Ihsan Aceh Besar. The data were collected by using multiple choice questions. The results showed that student learning outcomes were increased after the implementation of handout based on SETS. It can be concluded that the application of handout that is based on SETS approach can improve students learning outcomes on Biotechnology concept in MAS Darul Ihsan Aceh Besar.
Keywords	handout ; sets approach ; learning outcomes and biotechnology ; Biology (General) ; QH301-705.5
Subject code	028
Language	English
Publishing date	2019-11-01T00:00:00Z
Publisher	Universitas Islam Negeri Ar-Raniry
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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