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Article ; Online: Dalfampridine in the treatment of primary fatigue in patients with multiple sclerosis: a randomized clinical trail.

Mavandadi, Shirin / Paybast, Sepideh / Mirzadeh, Monirsadat / Mozhdehipanah, Hossein

2024

Abstract: Introduction: Fatigue is a highly prevalent debilitating symptom among patients with multiple sclerosis (PwMS), which markedly affects the quality of life. The present study aimed to evaluate the effect of extended-release fampridine on fatigue in PwMS.! ...

Abstract	Introduction: Fatigue is a highly prevalent debilitating symptom among patients with multiple sclerosis (PwMS), which markedly affects the quality of life. The present study aimed to evaluate the effect of extended-release fampridine on fatigue in PwMS. Methods: This was a randomized, double-blind clinical trial on 77 PwMS with a complaint of fatigue, aged over 18 years old, randomized to extended-release fampridine (n = 44) or placebo (n = 35) for 12 weeks. Fatigue and motor function were assessed at baseline and end point. Results: A total of 88 patients were recruited, of whom 77 were analyzed. 80.5% were female, with a median age of 38. 87% were diagnosed with relapsing-remitting MS (RRMS) with a median disease duration of 96 months. Fingolimod (37.7%) was considered the most frequently used DMT, followed by ani-CD20s (32.5%). The total median MFIS score was 43.5 and 37 in the fampridine and placebo groups which were not significantly different (p > 0.05). After 12 weeks, the total MFIS improved in both groups compared to the baseline, which was significant in the active group (p = 0.04). However, the final end point total MFIS was still comparable between the two groups (p = 0.11). Conclusion: The present study revealed a positive short-term effect of extended-release fampridine on MFIS in PwMS. However, this effect was not significantly superior to the placebo.
Language	English
Publishing date	2024-04-06
Publishing country	Italy
Document type	Journal Article
ZDB-ID	127315-2
ISSN	2240-2993 ; 0300-9009
ISSN (online)	2240-2993
ISSN	0300-9009
DOI	10.1007/s13760-024-02508-x
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Article ; Online: The Effectiveness of Cognitive-Behavioral Intervention on Dental Anxiety during Pulpotomy in 7-10 Year-Old Children: A Clinical Trial.

Shokravi, Marzieh / Maaboudi, Mohammadreza / Amiri, Ali / Mirzadeh, Monirsadat / Jabbarian, Razieh

Frontiers in dentistry

2023 Volume 20, Page(s) 32

Abstract: Objectives: ...

Abstract	Objectives:
Language	English
Publishing date	2023-08-26
Publishing country	Iran
Document type	Journal Article
ISSN	2676-296X
ISSN (online)	2676-296X
DOI	10.18502/fid.v20i32.13588
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Article: Parent's Attitudes toward Their Children's Oral Health Care during the COVID-19 Pandemic: A Cross-Sectional Study.

Zarabadipour, Mahdieh / Mokhlesi, Aida / Poorsoleiman, Taniya / Mirzadeh, Monirsadat

International journal of dentistry

2023 Volume 2023, Page(s) 7340105

Abstract: Background: The COVID-19 pandemic has significantly impacted global health and presented challenges to maintaining oral health in children. Efficient management and prevention of oral diseases are therefore crucial in this population.: Aim: This ... ...

Abstract	Background: The COVID-19 pandemic has significantly impacted global health and presented challenges to maintaining oral health in children. Efficient management and prevention of oral diseases are therefore crucial in this population. Aim: This cross-sectional study aimed to assess parents' self-reported oral and dental hygiene habits for their children during the COVID-19 pandemic. Methods: A total of 256 parents of primary school children in Qazvin completed an online questionnaire containing demographic, general, and cardinal questions. The collected data were analyzed using SPSS 22 software, and accurate analytical tests were run to reach the results. Results: The study found that 69.1% of parents and 87.1% of children brushed their teeth regularly during the pandemic. Additionally, 80.5% of parents monitored their children while brushing. While some parents expressed concerns about COVID-19 infection, parents from lower socioeconomic status reported a higher willingness to attend dental centers than those from more prosperous areas. Conclusion: These findings suggest that parents' supervision and attitude toward oral health care significantly affect children's oral hygiene habits during the pandemic, possibly due to increased time spent together during lockdowns.
Language	English
Publishing date	2023-07-11
Publishing country	Egypt
Document type	Journal Article
ZDB-ID	2546524-7
ISSN	1687-8736 ; 1687-8728
ISSN (online)	1687-8736
ISSN	1687-8728
DOI	10.1155/2023/7340105
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Article ; Online: Phenotypic and genotypic characterization of virulence markers and antifungal susceptibility of oral Candida species from diabetic and non-diabetic hemodialysis patients.

Mohammadi, Faezeh / Charkhchian, Maliheh / Mirzadeh, Monirsadat

BMC oral health

2023 Volume 23, Issue 1, Page(s) 261

Abstract: Background: Patients with chronic kidney disease undergoing hemodialysis are often colonized by Candida species with high possibility of fungal infections. The purposes of this study were to determine the prevalence of Candida species, evaluate ... ...

Abstract	Background: Patients with chronic kidney disease undergoing hemodialysis are often colonized by Candida species with high possibility of fungal infections. The purposes of this study were to determine the prevalence of Candida species, evaluate antifungal susceptibility profile, biofilm formation, proteinase and phospholipase activities, and the frequency of virulence genes in the Candida species isolated from the oral mucosa of hemodialysis diabetic (DM) and non-diabetic (non-DM) patients. Methods: This study identified several species of Candida isolated from 69 DM and 58 non-DM patients on hemodialysis using phenotypic methods and PCR-RFLP technique. The identification of C. albicans and C. glabrata complex was performed by HWP1 gene and four oligonucleotides (UNI-5.8S, GLA-f, BRA-f, and NIV-f), respectively. Antifungal susceptibility to amphotericin B, fluconazole, itraconazole, voriconazole, and caspofungin was assessed according to CLSI M27-A3/S4. The biomass, metabolic activity of biofilm, proteinase (P Results: Candida prevalence was 44.9% with 47.8% and 41.4% among DM and non-DM patients, respectively (P = .045). The species identified were C. albicans (49.5%), C. glabrata (16.5%), C. tropicalis (12%), C. kefyr (8.8%), C. parapsilosis (6.6%), C. dubliniensis (3.3%), and C. lusitaniae (3.3%). The antifungal susceptibility profile showed that all Candida isolates were sensitive to amphotericin B, itraconazole, voriconazole, and caspofungin whereas fluconazole resistance was observed in 6.3% (MIC ≥ 64 μg/mL) of C. albicans and 6.6% of C. glabrata (MIC ≥ 64 μg/mL). The susceptible- dose-dependent rate was found in 10.5% of C. albicans. The P Conclusions: These results showed the importance of prevalence of NAC species in hemodialysis patients. Investigating antifungal susceptibility profile made a better understanding of the role of virulence markers in the pathogenesis of Candida strains.
MeSH term(s)	Humans ; Antifungal Agents/pharmacology ; Fluconazole ; Amphotericin B ; Caspofungin ; Itraconazole ; Voriconazole ; Virulence/genetics ; Candida/genetics ; Candida albicans ; Phospholipases ; Candida glabrata/genetics ; Microbial Sensitivity Tests ; Peptide Hydrolases/genetics ; Drug Resistance, Fungal/genetics
Chemical Substances	Antifungal Agents ; Fluconazole (8VZV102JFY) ; Amphotericin B (7XU7A7DROE) ; Caspofungin (F0XDI6ZL63) ; Itraconazole (304NUG5GF4) ; Voriconazole (JFU09I87TR) ; Phospholipases (EC 3.1.-) ; Peptide Hydrolases (EC 3.4.-)
Language	English
Publishing date	2023-05-04
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2091511-1
ISSN	1472-6831 ; 1472-6831
ISSN (online)	1472-6831
ISSN	1472-6831
DOI	10.1186/s12903-023-02970-8
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Article ; Online: Pregnant women in the exposure to COVID-19 infection outbreak: the unseen risk factors and preventive healthcare patterns.

Mirzadeh, Monirsadat / Khedmat, Leila

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

2020 Volume 35, Issue 7, Page(s) 1377–1378

MeSH term(s)	COVID-19 ; Delivery of Health Care ; Disease Outbreaks/prevention & control ; Female ; Humans ; Pregnancy ; Pregnant Women ; Risk Factors ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-04-07
Publishing country	England
Document type	Letter
ZDB-ID	2077261-0
ISSN	1476-4954 ; 1057-0802 ; 1476-7058
ISSN (online)	1476-4954
ISSN	1057-0802 ; 1476-7058
DOI	10.1080/14767058.2020.1749257
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Article ; Online: Relationship between health literacy level and sexual function in women in the Northwest of Iran in 2020- a cross sectional study.

Barikani, Ameneh / Samani Kia, Mahsa / Khoshkchali, Atefeh / Mirzadeh, Monirsadat

BMC women's health

2023 Volume 23, Issue 1, Page(s) 176

Abstract: Background and purpose: Sexual health means coordination and adaptation of physical, emotional, intellectual and social aspects of human beings. One of the variables that affect sexual function and sexual satisfaction is health literacy. The aim of this ...

Abstract	Background and purpose: Sexual health means coordination and adaptation of physical, emotional, intellectual and social aspects of human beings. One of the variables that affect sexual function and sexual satisfaction is health literacy. The aim of this study was to investigate the relationship between health literacy level and sexual function in married women in Qazvin health centers. Methods: In the cross-sectional study, 340 married women were selected from four health centers in Qazvin, Iran, in 2020. These selected centers were chosen randomly from 26 health centers. Participants were included in the study by using the proportional selection method based on the sample size of the all health centers. Data collection tools include three questionnaires: demographic information, The Health Literacy Questionnaire (HELIA), and Female Sexual Function Index (FSFI). Data were analyzed using SPSS 24 software. A significance level of P < 0.05 was considered for statistical analyses. Results: The highest and lowest scores of dimension's sexual function are satisfaction, pain, and lubricant, respectively. The level of women's health literacy in Qazvin was inadequate and borderline (56.4%). Each of the sexual function dimensions had significant positive correlations with health literacy (P < 0.001). There was a significant relationship between health literacy level with age, education, and occupation (P < 0.05). According to linear regression analysis, with the increase in years of marriage, sexual function is decreased (P < 0.02). Conclusion: Health literacy was inadequate in more than half of the study sample and health literacy was significantly associated with sexual function. Educational programs were necessary in order to promote women's health literacy in health centers.
MeSH term(s)	Female ; Humans ; Sexual Behavior/psychology ; Cross-Sectional Studies ; Health Literacy ; Iran ; Orgasm
Language	English
Publishing date	2023-04-11
Publishing country	England
Document type	Journal Article
ZDB-ID	2050444-5
ISSN	1472-6874 ; 1472-6874
ISSN (online)	1472-6874
ISSN	1472-6874
DOI	10.1186/s12905-023-02322-2
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Article ; Online: Cone-Beam Computed Tomographic Evaluation of Artifact Effects of Three Different Sealers.

Tofangchiha, Maryam / Bolbolian, Marjan / Rahrovan, Sahar / Mirzadeh, Monirsadat / Hajihassani, Neda

Iranian endodontic journal

2023 Volume 13, Issue 4, Page(s) 545–548

Abstract: Introduction: Cone-beam computed tomography (CBCT) is one of the most important diagnostic tools in maxillofacial imaging. Nowadays different sealers are used in root canal therapy and some of them can create artifact in CBCT images. The aim of this ... ...

Abstract	Introduction: Cone-beam computed tomography (CBCT) is one of the most important diagnostic tools in maxillofacial imaging. Nowadays different sealers are used in root canal therapy and some of them can create artifact in CBCT images. The aim of this study was to evaluate the effect of different sealers including AH-26, Diadent, and Anyseal in creation of artifact bands in the CBCT images based on voxel size. Methods and materials: A total of 44 single rooted extracted teeth were selected. The canals were prepared by crown-down technique. All teeth were manually filed up to master apical file (MAF) size 45 and 1 mm shorter than the apical foramen. The teeth were divided into 4 equal groups. The canals were filled with gutta-percha and either of sealers AH-26, Diadent or Anyseal by lateral condensation technique. The control group were filled just with gutta-percha without any sealer. The CBCT images were taken in voxel sizes of 0.3 and 0.15. The Fisher exact and McNemar tests were used for statistical analysis. Results: Although, the control group had the lowest ratio of presence to absence of artifact, the ratio of presence to absence of artifact in voxel size of 0.3 and 0.15 mm were significantly lower in Anyseal than AH-26 ( Conclusion: In this
Language	English
Publishing date	2023-02-27
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2684659-7
ISSN	2008-2746 ; 2008-2746
ISSN (online)	2008-2746
ISSN	2008-2746
DOI	10.22037/iej.v13i4.19743
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Article: Knowledge Enhancement of Elementary School Staff about Traumatic Dental Injuries Using Different Educational Tools.

Salehi Karizmeh, Mojtaba / Mozaffari, Fatemeh / Mirzadeh, Monirsadat / Jabbarian, Razieh

International journal of dentistry

2023 Volume 2023, Page(s) 9167041

Abstract: Introduction: This study aimed to assess the efficacy of different educational tools for knowledge enhancement of elementary school staff about the management of traumatic dental injuries (TDIs).: Materials and methods: This quasi-experimental ( ... ...

Abstract	Introduction: This study aimed to assess the efficacy of different educational tools for knowledge enhancement of elementary school staff about the management of traumatic dental injuries (TDIs). Materials and methods: This quasi-experimental (pretest-posttest) study was conducted on 126 elementary school staff in Qazvin city, who were randomly selected by the cluster sampling in 2020. The baseline knowledge level of the participants about TDIs was assessed by an online questionnaire. Next, they were randomized into the poster, video clip, and no-intervention control groups (56 samples in each group). An informatory poster and a video clip about TDIs were sent to the participants in the first two groups, respectively, through the WhatsApp instant messaging app, and the knowledge level of the three groups was assessed again after 3 weeks. Data were analyzed by ANOVA, McNemar test, chi-square test, and Results: A significant correlation was noted between the baseline knowledge level of the participants and their educational level, participation in first aid courses covering TDIs, and history of encountering TDIs ( Conclusion: Despite the low-baseline knowledge level of the elementary school staff in Qazvin city about TDIs, their knowledge level significantly improved after the educational interventions.
Language	English
Publishing date	2023-12-06
Publishing country	Egypt
Document type	Journal Article
ZDB-ID	2546524-7
ISSN	1687-8736 ; 1687-8728
ISSN (online)	1687-8736
ISSN	1687-8728
DOI	10.1155/2023/9167041
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Article ; Online: Relationship between health literacy level and sexual function in women in the Northwest of Iran in 2020- a cross sectional study

Ameneh Barikani / Mahsa Samani kia / Atefeh Khoshkchali / Monirsadat Mirzadeh

BMC Women's Health, Vol 23, Iss 1, Pp 1-

2023 Volume 6

Abstract: Abstract Background and purpose Sexual health means coordination and adaptation of physical, emotional, intellectual and social aspects of human beings. One of the variables that affect sexual function and sexual satisfaction is health literacy. The aim ... ...

Abstract	Abstract Background and purpose Sexual health means coordination and adaptation of physical, emotional, intellectual and social aspects of human beings. One of the variables that affect sexual function and sexual satisfaction is health literacy. The aim of this study was to investigate the relationship between health literacy level and sexual function in married women in Qazvin health centers. Methods In the cross-sectional study, 340 married women were selected from four health centers in Qazvin, Iran, in 2020. These selected centers were chosen randomly from 26 health centers. Participants were included in the study by using the proportional selection method based on the sample size of the all health centers. Data collection tools include three questionnaires: demographic information, The Health Literacy Questionnaire (HELIA), and Female Sexual Function Index (FSFI). Data were analyzed using SPSS 24 software. A significance level of P < 0.05 was considered for statistical analyses. Results The highest and lowest scores of dimension’s sexual function are satisfaction, pain, and lubricant, respectively. The level of women’s health literacy in Qazvin was inadequate and borderline (56.4%). Each of the sexual function dimensions had significant positive correlations with health literacy (P < 0.001). There was a significant relationship between health literacy level with age, education, and occupation (P < 0.05). According to linear regression analysis, with the increase in years of marriage, sexual function is decreased (P < 0.02). Conclusion Health literacy was inadequate in more than half of the study sample and health literacy was significantly associated with sexual function. Educational programs were necessary in order to promote women’s health literacy in health centers.
Keywords	Health literacy ; Sexual function ; Women ; Married ; Education ; Gynecology and obstetrics ; RG1-991 ; Public aspects of medicine ; RA1-1270
Subject code	360 ; 302
Language	English
Publishing date	2023-04-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Effect of vitamin D vaginal suppository on sexual functioning among postmenopausal women: A three-arm randomized controlled clinical trial.

Sarebani, Zinat / Chegini, Venus / Chen, Hui / Aali, Ehsan / Mirzadeh, Monirsadat / Abbaspour, Mohammadreza / Griffiths, Mark D / Alimoradi, Zainab

Obstetrics & gynecology science

2023 Volume 66, Issue 5, Page(s) 462

Language	English
Publishing date	2023-09-15
Publishing country	Korea (South)
Document type	Published Erratum
ZDB-ID	2814367-X
ISSN	2287-8580 ; 2287-8572
ISSN (online)	2287-8580
ISSN	2287-8572
DOI	10.5468/ogs.22038.e1
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