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  1. Article ; Online: Persistent fever due to acute pancreatic graft rejection.

    Montagud-Marrahí, Enrique / Ventura-Aguiar, Pedro / Diekmann, Fritz

    Kidney international

    2019  Volume 96, Issue 5, Page(s) 1242

    MeSH term(s) Adult ; Female ; Fever of Unknown Origin/diagnostic imaging ; Fever of Unknown Origin/etiology ; Graft Rejection/complications ; Graft Rejection/diagnostic imaging ; Graft Rejection/therapy ; Humans ; Kidney Transplantation ; Pancreas Transplantation/adverse effects ; Positron Emission Tomography Computed Tomography ; Postoperative Complications/diagnostic imaging ; Postoperative Complications/etiology ; Postoperative Complications/therapy
    Language English
    Publishing date 2019-10-24
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1016/j.kint.2019.06.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 797: Show issues Location:
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  2. Article ; Online: Donor insulin use during stay in the intensive care unit should not preclude pancreas transplantation.

    Ventura-Aguiar, Pedro / Montagud-Marrahi, Enrique / Amor, Antonio J / Diekmann, Fritz

    Diabetologia

    2021  Volume 64, Issue 9, Page(s) 2122–2123

    MeSH term(s) Graft Survival ; Humans ; Insulins ; Intensive Care Units ; Pancreas Transplantation ; Tissue Donors
    Chemical Substances Insulins
    Language English
    Publishing date 2021-05-29
    Publishing country Germany
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1694-9
    ISSN 1432-0428 ; 0012-186X
    ISSN (online) 1432-0428
    ISSN 0012-186X
    DOI 10.1007/s00125-021-05479-3
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 279: Show issues Location:
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  3. Article ; Online: Liposomal iron in moderate chronic kidney disease.

    Montagud-Marrahi, Enrique / Arrizabalaga, Pilar / Abellana, Rosa / Poch, Esteban

    Nefrologia

    2019  Volume 40, Issue 4, Page(s) 446–452

    Abstract: Introduction and objective: The optimal iron supplementation route of administration (intravenous vs oral) in patients with chronic kidney disease (CKD) not on dialysis is a hot topic of debate. An oral preparation (liposomal iron, FeSu) has recently ... ...

    Title translation Hierro liposomal en la enfermedad renal crónica moderada.
    Abstract Introduction and objective: The optimal iron supplementation route of administration (intravenous vs oral) in patients with chronic kidney disease (CKD) not on dialysis is a hot topic of debate. An oral preparation (liposomal iron, FeSu) has recently been developed with high bioavailability and low incidence of side effects. The objective was to evaluate the efficacy of FeSu in patients with stage 3 CKD and gastrointestinal intolerance to conventional oral iron therapy.
    Material and methods: Prospective observational study of patients with stable stage 3 CKD and gastrointestinal intolerance to conventional oral iron therapy. An oral 30mg/day dose of FeSu was administered for 12 months. The primary outcome measure was haemoglobin increase at 6 and 12 months. Treatment adherence and adverse effects were also evaluated.
    Results: 37 patients aged 72.6±14.7 years and with an estimated glomerular filtration rate (eGFR) of 42±10ml/min/1.73m
    Conclusions: FeSu is effective in a cohort of patients with stage 3 CKD with similar characteristics to the general population of moderate CKD patients, with a low rate of adverse reactions and excellent tolerability.
    MeSH term(s) Aged ; Aged, 80 and over ; Anemia, Iron-Deficiency/drug therapy ; Anemia, Iron-Deficiency/etiology ; Female ; Humans ; Iron Compounds/administration & dosage ; Liposomes ; Male ; Middle Aged ; Prospective Studies ; Renal Insufficiency, Chronic/complications ; Severity of Illness Index ; Treatment Outcome
    Chemical Substances Iron Compounds ; Liposomes
    Language Spanish
    Publishing date 2019-12-28
    Publishing country Spain
    Document type Journal Article ; Observational Study
    ZDB-ID 2837917-2
    ISSN 2013-2514 ; 2013-2514
    ISSN (online) 2013-2514
    ISSN 2013-2514
    DOI 10.1016/j.nefro.2019.10.006
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  4. Article: Corrigendum:

    Montagud-Marrahi, Enrique / Luque, Yosu / Ros, Ruben Rabadan / Ajami, Tarek / Cuadrado-Payan, Elena / Estrella, Hector / Arancibia, Andres / Sánchez-Etayo, Gerard / Bohils, Marc / Marrero, Ramsés / Fundora, Yilliam / Ramírez-Bajo, Maria José / Banon-Maneus, Elisenda / Rovira, Jordi / Larque, Ana-Belén / Campistol, Josep Maria / Diekmann, Fritz / Musquera, Mireia

    Frontiers in bioengineering and biotechnology

    2024  Volume 12, Page(s) 1397979

    Abstract: This corrects the article DOI: 10.3389/fbioe.2023.1330043.]. ...

    Abstract [This corrects the article DOI: 10.3389/fbioe.2023.1330043.].
    Language English
    Publishing date 2024-03-21
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2024.1397979
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  5. Article: Ex vivo

    Montagud-Marrahi, Enrique / Luque, Yosu / Ros, Ruben Rabadan / Ajami, Tarek / Cuadrado-Payan, Elena / Estrella, Hector / Arancibia, Andres / Sánchez-Etayo, Gerard / Bohils, Marc / Marrero, Ramsés / Fundora, Yilliam / Ramírez-Bajo, Maria José / Banon-Maneus, Elisenda / Rovira, Jordi / Larque, Ana-Belén / Campistol, Josep Maria / Diekmann, Fritz / Musquera, Mireia

    Frontiers in bioengineering and biotechnology

    2024  Volume 11, Page(s) 1330043

    Abstract: The transplant community is focused on prolonging ... ...

    Abstract The transplant community is focused on prolonging the
    Language English
    Publishing date 2024-01-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2023.1330043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Rapid re-transplantation safety following early kidney graft loss.

    Rodríguez-Espinosa, Diana / Broseta, José Jesús / Hermida, Evelyn / Cuadrado, Elena / Guillén-Olmos, Elena / Montagud-Marrahi, Enrique / Diekmann, Fritz

    Nephrology (Carlton, Vic.)

    2021  Volume 26, Issue 9, Page(s) 742–747

    Abstract: Introduction: Early graft loss is a devastating kidney transplant complication associated with high mortality and an increased risk of sensitization to antigens from the failed graft. Moreover, if rapid re-transplantation were to occur, given that the ... ...

    Abstract Introduction: Early graft loss is a devastating kidney transplant complication associated with high mortality and an increased risk of sensitization to antigens from the failed graft. Moreover, if rapid re-transplantation were to occur, given that the human leukocyte antigen antibodies identification may not be reliable until several weeks after transplantation, the recipient's immunological status would be uncertain. Hence, there could be an increased immunological risk. To date, there is no information on whether a rapid re-transplantation after early graft loss, without a new reliable anti-HLA determination, is safe.
    Methods: We retrospectively analysed the number of rejections and the graft survival of re-transplanted patients with early graft loss (defined as graft failure before 30 days from transplant) from our centre between June 2003 and November 2019. The studied population was divided into rapid re-transplantation (performed within 30 days of early graft loss) and late re-transplantation (performed beyond those 30 days).
    Results: Forty-seven patients were re-transplanted after early graft loss. There were nine rapid re-transplantation cases with an 89% five-year graft survival and one antibody-mediated rejection episode. Furthermore, we identified 38 cases of late re-transplantation with a 69% five-year graft survival, 4 T cell-mediated, and 11 antibody-mediated rejections.
    Conclusions: Rapid re-transplantation appears to be safe and does not entail increased rejection risk, nor does it impact long-term graft survival when compared to late re-transplantation.
    MeSH term(s) Adult ; Aged ; Female ; Graft Rejection/diagnosis ; Graft Rejection/epidemiology ; Graft Rejection/surgery ; Graft Survival ; Histocompatibility Testing ; Humans ; Kidney Failure, Chronic/diagnosis ; Kidney Failure, Chronic/epidemiology ; Kidney Failure, Chronic/surgery ; Kidney Transplantation/adverse effects ; Male ; Middle Aged ; Patient Selection ; Postoperative Complications/epidemiology ; Reoperation/adverse effects ; Retrospective Studies ; Time Factors ; Treatment Outcome
    Language English
    Publishing date 2021-06-05
    Publishing country Australia
    Document type Journal Article ; Observational Study
    ZDB-ID 1303661-0
    ISSN 1440-1797 ; 1320-5358
    ISSN (online) 1440-1797
    ISSN 1320-5358
    DOI 10.1111/nep.13907
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    Zs.A 4822: Show issues Location:
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  7. Article ; Online: Extracorporeal Photopheresis Improves Graft Survival in a Full-Mismatch Rat Model of Kidney Transplantation.

    Piñeiro, Gaston J / Lazo-Rodriguez, Marta / Ventura-Aguiar, Pedro / Ramirez-Bajo, Maria J / Banon-Maneus, Elisenda / Lozano, Miquel / Cid, Joan / Hierro-Garcia, Natalia / Cucchiari, David / Revuelta, Ignacio / Montagud-Marrahi, Enrique / Palou, Eduard / Bayés-Genís, Beatriu / Campistol, Josep M / Diekmann, Fritz / Rovira, Jordi

    Transplant international : official journal of the European Society for Organ Transplantation

    2023  Volume 36, Page(s) 10840

    Abstract: Extracorporeal photopheresis (ECP) is an immunomodulatory therapy based on the infusion of autologous cellular products exposed to ultraviolet light (UV) in the presence of a photosensitizer. The study evaluates the ECP efficacy as induction therapy in a ...

    Abstract Extracorporeal photopheresis (ECP) is an immunomodulatory therapy based on the infusion of autologous cellular products exposed to ultraviolet light (UV) in the presence of a photosensitizer. The study evaluates the ECP efficacy as induction therapy in a full-mismatch kidney transplant rat model. Dark Agouti to Lewis (DA-L) kidney transplant model has been established. ECP product was obtained from Lewis rat recipients after DA kidney graft transplantation (Lew
    MeSH term(s) Rats ; Animals ; Kidney Transplantation ; Photopheresis ; Graft Survival ; Rats, Inbred Lew ; Graft Rejection/prevention & control ; Antibodies
    Chemical Substances Antibodies
    Language English
    Publishing date 2023-01-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 639435-8
    ISSN 1432-2277 ; 0934-0874
    ISSN (online) 1432-2277
    ISSN 0934-0874
    DOI 10.3389/ti.2023.10840
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    Zs.A 2358: Show issues Location:
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  8. Article: Bariatric Surgery Outcomes in Patients with Chronic Kidney Disease.

    Pané, Adriana / Claro, Maria / Molina-Andujar, Alicia / Olbeyra, Romina / Romano-Andrioni, Bárbara / Boswell, Laura / Montagud-Marrahi, Enrique / Jiménez, Amanda / Ibarzabal, Ainitze / Viaplana, Judith / Ventura-Aguiar, Pedro / Amor, Antonio J / Vidal, Josep / Flores, Lilliam / de Hollanda, Ana

    Journal of clinical medicine

    2023  Volume 12, Issue 18

    Abstract: Obesity increases the risk of developing chronic kidney disease (CKD), which has a major negative impact on global health. Bariatric surgery (BS) has demonstrated a substantial improvement of obesity-related comorbidities and thus, it has emerged as a ... ...

    Abstract Obesity increases the risk of developing chronic kidney disease (CKD), which has a major negative impact on global health. Bariatric surgery (BS) has demonstrated a substantial improvement of obesity-related comorbidities and thus, it has emerged as a potential therapeutic tool in order to prevent end-stage renal disease. A limited number of publications to date have examined the beneficial effects and risks of BS in patients with non-advanced stages of CKD. We aimed to investigate the safety of BS in patients with CKD stages 3-4 (directly related or not to obesity) and both the metabolic/renal outcomes post-BS. A total of 57 individuals were included (n = 19 for CKD-group; n = 38 for patients with obesity, but normal eGFR [control-group]). Weight loss and obesity comorbidities resolution after BS were similar in both groups. Renal function (eGFR [CKD-EPI]) improved significantly at the 1-year follow-up: Δ10.2 (5.2-14.9) (
    Language English
    Publishing date 2023-09-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12186095
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  9. Article: Midnight Cortisol is Associated with Changes in Systolic Blood Pressure and Diabetic Neuropathy in Subjects with Type 1 Diabetes Undergoing Simultaneous Kidney-Pancreas Transplantation.

    Boswell, Laura / Amor, Antonio J / Montagud-Marrahi, Enrique / Casals, Gregori / Díaz-Catalan, Daniela / Banon-Maneus, Elisenda / Ramírez-Bajo, María José / Hierro, Natalia / Diekmann, Fritz / Musquera, Mireia / Serés-Noriega, Tonet / Esmatjes, Enric / Ferrer-Fàbrega, Joana / Ventura-Aguiar, Pedro / Hanzu, Felicia A

    Diabetes therapy : research, treatment and education of diabetes and related disorders

    2023  Volume 15, Issue 1, Page(s) 165–181

    Abstract: Introduction: An increased midnight cortisol (MC) has been described in end-stage kidney disease (ESKD) and type 1 diabetes (T1D). Lower circulating levels of the cytokine soluble tumor necrosis factor (TNF)-like weak inducer of apoptosis (sTWEAK) have ... ...

    Abstract Introduction: An increased midnight cortisol (MC) has been described in end-stage kidney disease (ESKD) and type 1 diabetes (T1D). Lower circulating levels of the cytokine soluble tumor necrosis factor (TNF)-like weak inducer of apoptosis (sTWEAK) have been found in T1D and ESKD and associated with cardiovascular (CV) events in the latter. We aimed to study MC and sTWEAK in simultaneous pancreas-kidney transplant (SPKT) recipients, and the association of these markers with CV risk factors and transplant outcomes.
    Methods: This was a retrospective cohort study including subjects with T1D who received a first SPKT between 2008 and 2020. MC and sTWEAK at baseline were correlated with CV risk factors and evolution 1 year after SPKT.
    Results: We included 29 subjects (58.6% women, mean age 43.5 ± 7.5 years, diabetes duration 31.9 ± 9.4 years). Systolic blood pressure (SBP) increased directly with MC quartiles, despite similar hypertension prevalence (p < 0.05). At 1 year, antihypertensive treatment was deintensified in those in lower MC quartiles (p < 0.05). Diabetic neuropathy prevalence decreased progressively in higher cortisol quartiles (p for trend = 0.005). Low MC was associated with delayed kidney graft function (p for trend = 0.044), and high sTWEAK with kidney graft rejection (p for trend = 0.018). In multivariate analyses, MC (standardized-β 0.505, p = 0.004) and age (standardized-β - 0.460, p = 0.040) were independently correlated with SBP, and MC was independently associated with the presence of diabetic neuropathy (OR 0.633, 95% CI 0.425-0.944, p = 0.025), adjusted for confounders.
    Conclusions: In this exploratory study, lower MC was associated with a lower baseline SBP, an improvement of antihypertensive treatment 1 year after transplant, and a higher diabetic neuropathy prevalence in SPKT recipients.
    Language English
    Publishing date 2023-11-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2566702-6
    ISSN 1869-6961 ; 1869-6953
    ISSN (online) 1869-6961
    ISSN 1869-6953
    DOI 10.1007/s13300-023-01487-1
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  10. Article: Tailoring the dialysate bicarbonate eliminates pre-dialysis acidosis and post-dialysis alkalosis.

    Cuadrado, Elena / Broseta, José Jesús / Rodríguez-Espinosa, Diana / Montagud-Marrahi, Enrique / Rodas, Lida / Fontseré, Néstor / Arias-Guillén, Marta / Rico, Naira / Maduell, Francisco

    Clinical kidney journal

    2022  Volume 15, Issue 10, Page(s) 1946–1951

    Abstract: Background: Both metabolic acidosis and alkalosis increase hospitalizations, haemodynamic instability and mortality in haemodialysis patients. Unfortunately, current practices opt for a one-size-fits-all approach, leaving many patients either acidotic ... ...

    Abstract Background: Both metabolic acidosis and alkalosis increase hospitalizations, haemodynamic instability and mortality in haemodialysis patients. Unfortunately, current practices opt for a one-size-fits-all approach, leaving many patients either acidotic before or alkalotic after dialysis sessions. Therefore an individualized adjustment of these patients' dialysate bicarbonate prescriptions could reduce these acid-base imbalances.
    Methods: This is a prospective single-cohort study of patients on a chronic haemodiafiltration programme. The dialysate bicarbonate prescription was modified according to the pre- and post-dialysis total carbon dioxide (TCO
    Results: At baseline, only 67.9% of patients were within the desired pre- and post-dialysis TCO
    Conclusions: We suggest an individualized adjustment of the dialysate bicarbonate concentration according to the pre- and post-dialysis TCO
    Language English
    Publishing date 2022-05-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfac128
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