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  1. Article ; Online: Retraction Note: CREB3L4 promotes angiogenesis and tumor progression in gastric cancer through regulating VEGFA expression.

    Wang, Nannan / Chen, Yuanneng / Shi, Chengwei / Lin, Zuoguang / Xie, Huaxia

    Cancer gene therapy

    2023  Volume 30, Issue 7, Page(s) 1040

    Language English
    Publishing date 2023-07-18
    Publishing country England
    Document type Retraction of Publication
    ZDB-ID 1212513-1
    ISSN 1476-5500 ; 0929-1903
    ISSN (online) 1476-5500
    ISSN 0929-1903
    DOI 10.1038/s41417-023-00613-2
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4125: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Semi-automated Hierarchical Clustering Model for 4D-STEM Datasets.

    Shi, Chuqiao / Mao, Nannan / Yang, Yao / Kong, Jing / Han, Yimo

    Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada

    2023  Volume 29, Issue Supplement_1, Page(s) 709–710

    Language English
    Publishing date 2023-08-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 1385710-1
    ISSN 1435-8115 ; 1431-9276
    ISSN (online) 1435-8115
    ISSN 1431-9276
    DOI 10.1093/micmic/ozad067.349
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Skin Conductance-Based Acupoint and Non-Acupoint Recognition Using Machine Learning.

    Shi, Feifei / Ning, Huansheng / Xiao, Ruoxiu / Zhu, Tao / Li, Nannan

    IEEE journal of biomedical and health informatics

    2024  Volume PP

    Abstract: Acupoints (APs) prove to have positive effects on disease diagnosis and treatment, while intelligent techniques for the automatic detection of APs are not yet mature, making them more dependent on manual positioning. In this paper, we realize the skin ... ...

    Abstract Acupoints (APs) prove to have positive effects on disease diagnosis and treatment, while intelligent techniques for the automatic detection of APs are not yet mature, making them more dependent on manual positioning. In this paper, we realize the skin conductance-based APs and non-APs recognition with machine learning, which could assist in APs detection and localization in clinical practice. Firstly, we collect skin conductance of traditional Five-Shu Point and their corresponding non-APs with wearable sensors, establishing a dataset containing over 36000 samples of 12 different AP types. Then, electrical features are extracted from the time domain, frequency domain, and nonlinear perspective respectively, following which typical machine learning algorithms (SVM, RF, KNN, NB, and XGBoost) are demonstrated to recognize APs and non-APs. The results demonstrate XGBoost with the best precision of 66.38%. Moreover, we also quantify the impacts of the differences among AP types and individuals, and propose a pairwise feature generation method to weaken the impacts on recognition precision. By using generated pairwise features, the recognition precision could be improved by 7.17%. The research systematically realizes the automatic recognition of APs and non-APs, and is conducive to pushing forward the intelligent development of APs and Traditional Chinese Medicine theories.
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2695320-1
    ISSN 2168-2208 ; 2168-2194
    ISSN (online) 2168-2208
    ISSN 2168-2194
    DOI 10.1109/JBHI.2024.3378211
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5483: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
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  4. Article ; Online: Cross-Linked Polyacrylic-Based Hydrogel Polymer Electrolytes for Flexible Supercapacitors.

    Shi, Lanxin / Jiang, Pengfei / Zhang, Pengxue / Duan, Nannan / Liu, Qi / Qin, Chuanli

    Polymers

    2024  Volume 16, Issue 6

    Abstract: Hydrogel polymer electrolytes (GPEs), as an important component of flexible energy storage devices, have gradually received wide attention compared with traditional liquid electrolytes due to their advantages of good mechanical, bending, and safety ... ...

    Abstract Hydrogel polymer electrolytes (GPEs), as an important component of flexible energy storage devices, have gradually received wide attention compared with traditional liquid electrolytes due to their advantages of good mechanical, bending, and safety properties. In this paper, two cross-linked GPEs of poly(acrylic acid-co-acrylamide) or poly(acrylic acid-co-N-methylolacrylamide) with NaNO
    Language English
    Publishing date 2024-03-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym16060800
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  5. Article ; Online: Room-Temperature Phosphorescence Materials Featuring Triplet Hybrid Local Charge Transfer Emission.

    Shi, Qiyuan / Ding, Nannan / Wang, Zhaolong / Gou, Xinyu / Peng, Lingya / Ma, Jiani / Fang, Yu

    The journal of physical chemistry letters

    2024  Volume 15, Issue 11, Page(s) 2995–3001

    Abstract: Room-temperature phosphorescence materials have found important applications in dissolved oxygen sensing, temperature monitoring, anticounterfeiting, etc., because of their prolonged phosphorescence lifetime. However, the known systems mainly utilize the ...

    Abstract Room-temperature phosphorescence materials have found important applications in dissolved oxygen sensing, temperature monitoring, anticounterfeiting, etc., because of their prolonged phosphorescence lifetime. However, the known systems mainly utilize the triplet local excited state emission, which is generally less sensitive to microenvironment perturbation. In this work, we designed a series of 4-phenyl-1,8-naphthalimide (NMI) derivatives containing different numbers of carbazole (Cz) units (denoted as NMI-Cz, NMI-2Cz, and NMI-3Cz). Steady state and time-resolved spectroscopy studies determined that the compounds undergo intramolecular through-space charge transfer in solution, yielding a triplet hybrid local charge transfer state. Room-temperature phosphorescence emission was observed in compound-doped poly(methyl methacrylate) thin films upon ammonia treatment. Interestingly, emission from different films exhibited different persistence times. We believe a film-based, time-resolved luminescent ammonia sensor could be developed by making a device of the emissive films as fabricated.
    Language English
    Publishing date 2024-03-08
    Publishing country United States
    Document type Journal Article
    ISSN 1948-7185
    ISSN (online) 1948-7185
    DOI 10.1021/acs.jpclett.4c00359
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  6. Article: Genome-Wide Identification and Expression Profile Reveal Potential Roles of Peanut

    Zhang, Zhen / Chen, Nannan / Zhang, Zheng / Shi, Gangrong

    Plants (Basel, Switzerland)

    2022  Volume 11, Issue 6

    Abstract: Zinc/iron-regulated transporter-like protein (ZIP) family genes play crucial roles in metal uptake and transport in plants. However, little is known about their functions in peanut. Here, genome-wide analysis identified 30 ... ...

    Abstract Zinc/iron-regulated transporter-like protein (ZIP) family genes play crucial roles in metal uptake and transport in plants. However, little is known about their functions in peanut. Here, genome-wide analysis identified 30 peanut
    Language English
    Publishing date 2022-03-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants11060786
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  7. Article ; Online: Regulation of the Function of T Follicular Helper Cells and B Cells in Type 1 Diabetes Mellitus by the OX40/OX40L Axis.

    Du, Xuan / Zhu, Yan / Lu, Wen / Fu, Nannan / Wang, Qin / Shi, Bimin

    The Journal of clinical endocrinology and metabolism

    2024  

    Abstract: Objective/main outcome: To study the expression of OX40 on T follicular helper (Tfh) cells and the ligand OX40L on antigen-presenting cells (APCs) in peripheral blood of patients with Type 1 diabetes mellitus (T1DM) and the role of OX40 signaling in ... ...

    Abstract Objective/main outcome: To study the expression of OX40 on T follicular helper (Tfh) cells and the ligand OX40L on antigen-presenting cells (APCs) in peripheral blood of patients with Type 1 diabetes mellitus (T1DM) and the role of OX40 signaling in promoting Tfh cells to assist B-cell differentiation.
    Design: Cross-sectional study.
    Setting: Endocrinology department of a university hospital.
    Participants: Twenty-five patients with T1DM and 35 with newly diagnosed T2DM from January 2021-December 2021 (39 males, 21 females; mean age: 31.0 ± 4.5, range: 19-46 years).
    Interventions: None.
    Methods: The peripheral blood proportion of CD4+CD25-CD127+CXCR5+PD1+ Tfh cells in patients with T1DM or T2DM and the OX40L expression in CD14+ monocytes and CD19+ B cells were analyzed by flow cytometry. The OX40 signal effect on Tfh-cell function was analyzed by co-incubating B cells with Tfh cells under different conditions. Flow cytometry detected the ratio of CD19-CD138+ plasmacytes.
    Results: The Tfh cells ratio and intracellular IL-21 expression in peripheral blood was significantly higher in patients with T1DM than with T2DM, and the OX40 expression in peripheral Tfh cells and OX40L expression in APC were significantly higher in T1DM. After adding OX40L protein, the CD19-CD138+-plasmacytes percentage was significantly increased and higher in T1DM. Blocking of anti-OX40L monoclonal antibodies significantly reduced the plasmacytes ratio.
    Conclusions: The peripheral Tfh cells proportion increased and the OX40 expression in peripheral Tfh cells was upregulated in patients with T1DM versus patients with T2DM. OX40/OX40L signaling enhanced the Tfh-cell function to assist B-cell differentiation, which may contribute to the pathogenesis of T1DM.
    Language English
    Publishing date 2024-04-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3029-6
    ISSN 1945-7197 ; 0021-972X
    ISSN (online) 1945-7197
    ISSN 0021-972X
    DOI 10.1210/clinem/dgae248
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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.134: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Neurotransmitter norepinephrine regulates chromatosomes aggregation and the formation of blotches in coral trout Plectropomus leopardus.

    Zhao, Nannan / Jiang, Ke / Ge, Xiaoyu / Huang, Jing / Wu, Caiming / Chen, Shi Xi

    Fish physiology and biochemistry

    2024  Volume 50, Issue 2, Page(s) 705–719

    Abstract: Color changes and pattern formations can represent strategies of the utmost importance for the survival of individuals or of species. Previous studies have associated capture with the formation of blotches (areas with light color) of coral trout, but the ...

    Abstract Color changes and pattern formations can represent strategies of the utmost importance for the survival of individuals or of species. Previous studies have associated capture with the formation of blotches (areas with light color) of coral trout, but the regulatory mechanisms link the two are lacking. Here, we report that capture induced blotches formation within 4-5 seconds. The blotches disappeared after anesthesia dispersed the pigment cells and reappeared after electrical stimulation. Subsequently, combining immunofluorescence, transmission electron microscopy and chemical sympathectomy, we found blotches formation results from activation of catecholaminergic neurons below the pigment layer. Finally, the in vitro incubation and intraperitoneal injection of norepinephrine (NE) induced aggregation of chromatosomes and lightening of body color, respectively, suggesting that NE, a neurotransmitter released by catecholaminergic nerves, mediates blotches formation. Our results demonstrate that acute stress response-induced neuronal activity can drive rapid changes in body color, which enriches our knowledge of physiological adaptations in coral reef fish.
    MeSH term(s) Animals ; Anthozoa ; Trout ; Norepinephrine/pharmacology ; Bass/physiology ; Coral Reefs
    Chemical Substances Norepinephrine (X4W3ENH1CV)
    Language English
    Publishing date 2024-01-31
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 292907-7
    ISSN 1573-5168 ; 0920-1742
    ISSN (online) 1573-5168
    ISSN 0920-1742
    DOI 10.1007/s10695-024-01300-1
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    In stock of ZB MED Bonn / Germany

    Z 6206: Show issues

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  9. Article ; Online: Aortic calcification accelerates cardiac dysfunction via inducing apoptosis of cardiomyocytes.

    Hao, Nannan / Yong, Hui / Zhang, Feifei / Liu, Chang / Qiu, Yulu / Shi, Yumeng / Li, Chunjian / Wang, Fang

    International journal of medical sciences

    2024  Volume 21, Issue 2, Page(s) 306–318

    Abstract: Vascular calcification (VC) is a known predictor of cardiovascular events in patients with atherosclerosis and chronic renal disease. However, the exact relationship between VC and cardiovascular mortality remains unclear. Herein, we investigated the ... ...

    Abstract Vascular calcification (VC) is a known predictor of cardiovascular events in patients with atherosclerosis and chronic renal disease. However, the exact relationship between VC and cardiovascular mortality remains unclear. Herein, we investigated the underlying mechanisms between VC progression, arterial stiffness, and cardiac dysfunction. C57BL/6 mice were administered intraperitoneally vitamin D
    MeSH term(s) Humans ; Rats ; Mice ; Animals ; Muscle, Smooth, Vascular/metabolism ; Myocytes, Cardiac/pathology ; Mice, Inbred C57BL ; Vascular Calcification/pathology ; Apoptosis ; Heart Diseases ; Myocytes, Smooth Muscle/metabolism
    Language English
    Publishing date 2024-01-01
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2151424-0
    ISSN 1449-1907 ; 1449-1907
    ISSN (online) 1449-1907
    ISSN 1449-1907
    DOI 10.7150/ijms.90324
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  10. Article ; Online: PM

    Guan, Linlin / Shi, Hao / Tian, Jiayu / Wang, Xin / Liu, Nannan / Wang, Caihong / Zhang, Zhihong

    Molecular immunology

    2023  Volume 161, Page(s) 74–81

    Abstract: Recent evidence has suggested that fine particulate matter ( ... ...

    Abstract Recent evidence has suggested that fine particulate matter (PM
    MeSH term(s) Rats ; Animals ; Inflammasomes/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; NLR Proteins ; Spleen/metabolism ; Rats, Sprague-Dawley ; Caspase 1/metabolism ; Particulate Matter/toxicity ; Autophagy
    Chemical Substances Inflammasomes ; NLR Family, Pyrin Domain-Containing 3 Protein ; NLR Proteins ; Caspase 1 (EC 3.4.22.36) ; Particulate Matter
    Language English
    Publishing date 2023-07-27
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 424427-8
    ISSN 1872-9142 ; 0161-5890
    ISSN (online) 1872-9142
    ISSN 0161-5890
    DOI 10.1016/j.molimm.2023.07.009
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 166: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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