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  1. Article ; Online: Suspending cross-team nursing care is necessary to prevent health care-associated infection during COVID-19 epidemic.

    Chen, Li-Chin / Wu, Lin-Kun / Chen, Mei-Hsing

    The Kaohsiung journal of medical sciences

    2020  Volume 36, Issue 11, Page(s) 955–956

    MeSH term(s) Betacoronavirus/pathogenicity ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/therapy ; Coronavirus Infections/transmission ; Female ; Hospitalization ; Humans ; Male ; Nurses/organization & administration ; Nursing, Team/organization & administration ; Pandemics/prevention & control ; Patient Transfer/organization & administration ; Personal Protective Equipment/supply & distribution ; Personnel, Hospital/education ; Personnel, Hospital/supply & distribution ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/therapy ; Pneumonia, Viral/transmission ; Practice Guidelines as Topic ; Psychological Distance ; SARS-CoV-2 ; Severity of Illness Index ; Taiwan/epidemiology
    Keywords covid19
    Language English
    Publishing date 2020-09-03
    Publishing country China (Republic : 1949- )
    Document type Letter
    ZDB-ID 639302-0
    ISSN 2410-8650 ; 0257-5655
    ISSN (online) 2410-8650
    ISSN 0257-5655
    DOI 10.1002/kjm2.12289
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 3187: Show issues Location:
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  2. Article ; Online: Synthesis and Biological Activities of 11- and 12-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB and Tyrosyl-DNA Phosphodiesterase 1 Inhibitors.

    Yang, Hao / Qin, Chao / Wu, Min / Wang, Fang-Ting / Wang, Wenjie / Agama, Keli / Pommier, Yves / Hu, De-Xuan / An, Lin-Kun

    ChemMedChem

    2023  Volume 18, Issue 10, Page(s) e202200593

    Abstract: Herein, a series of 11- or 12-substituted benzophenanthridinone derivatives was designed and synthesized for the discovery of dual topoisomerase IB (TOP1) and tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors. Enzyme-based assays indicated that two ... ...

    Abstract Herein, a series of 11- or 12-substituted benzophenanthridinone derivatives was designed and synthesized for the discovery of dual topoisomerase IB (TOP1) and tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors. Enzyme-based assays indicated that two compounds 12 and 38 showed high TOP1 inhibitory potency (+++), and four compounds 35, 37, 39 and 43 showed good TDP1 inhibition with IC
    MeSH term(s) Humans ; Phosphodiesterase Inhibitors/pharmacology ; DNA Topoisomerases, Type I/metabolism ; Topotecan ; Phosphoric Diester Hydrolases/metabolism ; Topoisomerase I Inhibitors/pharmacology
    Chemical Substances tyrosyl-DNA phosphodiesterase (EC 3.1.4.-) ; Phosphodiesterase Inhibitors ; DNA Topoisomerases, Type I (EC 5.99.1.2) ; Topotecan (7M7YKX2N15) ; Phosphoric Diester Hydrolases (EC 3.1.4.-) ; Topoisomerase I Inhibitors ; TDP1 protein, human (EC 3.1.4.-)
    Language English
    Publishing date 2023-03-17
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Intramural
    ZDB-ID 2218496-X
    ISSN 1860-7187 ; 1860-7179
    ISSN (online) 1860-7187
    ISSN 1860-7179
    DOI 10.1002/cmdc.202200593
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6280: Show issues Location:
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  3. Article ; Online: Suspending cross‐team nursing care is necessary to prevent health care‐associated infection during COVID‐19 epidemic

    Li‐Chin Chen / Lin‐Kun Wu / Mei‐Hsing Chen

    Kaohsiung Journal of Medical Sciences, Vol 36, Iss 11, Pp 955-

    2020  Volume 956

    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2020-11-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Book: Chung-kuo sen lin k'un ch'ung ming lu

    Yang, Hsiu-yüan / Wu, Jian

    1981  

    Title translation Famous list of Chinese forest insects.
    Author's details Yang Hsiu-yüan, Wu Chien pien
    Keywords Forest insects/Nomenclature.
    Language Chinese
    Size 2, 8, 444 p. ;, 19 cm.
    Edition Ti 1 pan.
    Publisher Chung-kuo lin yeh ch'u pan she ; Hsin hua shu tien Pei-ching fa hsing so fa hsing
    Publishing place Pei-ching
    Document type Book
    Note English title on t.p. verso: A check list of the forest insects of China. ; Includes indexes.
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Preparedness for the next emerging infectious disease outbreak by implementing strategic human resource management.

    Wu, Lin-Kun / Su, Wen-Hui / Hsiao, Shih-Huai / Hou, Ming-Feng

    Journal of the Chinese Medical Association : JCMA

    2020  Volume 83, Issue 10, Page(s) 973–974

    MeSH term(s) COVID-19/prevention & control ; Communicable Diseases, Emerging/epidemiology ; Communicable Diseases, Emerging/prevention & control ; Disease Outbreaks/prevention & control ; Humans ; Taiwan/epidemiology ; Workforce
    Keywords covid19
    Language English
    Publishing date 2020-09-04
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2107283-8
    ISSN 1728-7731 ; 1726-4901
    ISSN (online) 1728-7731
    ISSN 1726-4901
    DOI 10.1097/JCMA.0000000000000423
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2699: Show issues Location:
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  6. Article ; Online: New Indole Diketopiperazine Alkaloids from Soft Coral-Associated Epiphytic Fungus Aspergillus versicolor CGF 9-1-2.

    Hu, Jin-Shan / He, Yu-Pei / Zhou, Feng-Guo / Wu, Ping-Ping / Chen, Le-Yi / Ni, Cheng / Zhang, Ze-Kun / Xiao, Xi-Ji / An, Lin-Kun / He, Xi-Xin / Zhang, Cui-Xian

    Chemistry & biodiversity

    2023  Volume 20, Issue 6, Page(s) e202300301

    Abstract: Two new indole diketopiperazine alkaloids (IDAs), (+)19-epi-sclerotiamide (1) and (-)19-epi-sclerotiamide (2), along with 13 known analogs (3-15), were isolated from a soft coral-associated epiphytic fungus Aspergillus versicolor CGF 9-1-2. The ... ...

    Abstract Two new indole diketopiperazine alkaloids (IDAs), (+)19-epi-sclerotiamide (1) and (-)19-epi-sclerotiamide (2), along with 13 known analogs (3-15), were isolated from a soft coral-associated epiphytic fungus Aspergillus versicolor CGF 9-1-2. The structures of two new compounds were established based on the combination of HR-ESI-MS, 1D and 2D NMR spectroscopy, optical rotation measurements and quantum chemical
    MeSH term(s) Animals ; Diketopiperazines/pharmacology ; Diketopiperazines/chemistry ; Molecular Docking Simulation ; ErbB Receptors/metabolism ; Lung Neoplasms ; Mutation ; Protein Kinase Inhibitors/metabolism ; Aspergillus/chemistry ; Indole Alkaloids/chemistry ; Agaricales ; Anthozoa/metabolism ; Molecular Structure
    Chemical Substances sclerotiamide ; Diketopiperazines ; ErbB Receptors (EC 2.7.10.1) ; Protein Kinase Inhibitors ; Indole Alkaloids
    Language English
    Publishing date 2023-05-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2139001-0
    ISSN 1612-1880 ; 1612-1872
    ISSN (online) 1612-1880
    ISSN 1612-1872
    DOI 10.1002/cbdv.202300301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: A Rare Cause of Recurrent Cardiogenic Shock and Flash Pulmonary Edema-Concealed Atrial Lead Dysfunction.

    Wu, Yuan-Kun Aden / Yu, Chih-Chieh / Lin, Jiunn-Lee

    Acta Cardiologica Sinica

    2023  Volume 39, Issue 3, Page(s) 488–491

    Language English
    Publishing date 2023-04-26
    Publishing country China (Republic : 1949- )
    Document type Journal Article
    ZDB-ID 1051394-2
    ISSN 1011-6842
    ISSN 1011-6842
    DOI 10.6515/ACS.202305_39(3).20230129A
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Development of revised ResNet-50 for diabetic retinopathy detection.

    Lin, Chun-Ling / Wu, Kun-Chi

    BMC bioinformatics

    2023  Volume 24, Issue 1, Page(s) 157

    Abstract: Background: Diabetic retinopathy (DR) produces bleeding, exudation, and new blood vessel formation conditions. DR can damage the retinal blood vessels and cause vision loss or even blindness. If DR is detected early, ophthalmologists can use lasers to ... ...

    Abstract Background: Diabetic retinopathy (DR) produces bleeding, exudation, and new blood vessel formation conditions. DR can damage the retinal blood vessels and cause vision loss or even blindness. If DR is detected early, ophthalmologists can use lasers to create tiny burns around the retinal tears to inhibit bleeding and prevent the formation of new blood vessels, in order to prevent deterioration of the disease. The rapid improvement of deep learning has made image recognition an effective technology; it can avoid misjudgments caused by different doctors' evaluations and help doctors to predict the condition quickly. The aim of this paper is to adopt visualization and preprocessing in the ResNet-50 model to improve module calibration, to enable the model to predict DR accurately.
    Results: This study compared the performance of the proposed method with other common CNNs models (Xception, AlexNet, VggNet-s, VggNet-16 and ResNet-50). In examining said models, the results alluded to an over-fitting phenomenon, and the outcome of the work demonstrates that the performance of the revised ResNet-50 (Train accuracy: 0.8395 and Test accuracy: 0.7432) is better than other common CNNs (that is, the revised structure of ResNet-50 could avoid the overfitting problem, decease the loss value, and reduce the fluctuation problem).
    Conclusions: This study proposed two approaches to designing the DR grading system: a standard operation procedure (SOP) for preprocessing the fundus image, and a revised structure of ResNet-50, including an adaptive learning rating to adjust the weight of layers, regularization and change the structure of ResNet-50, which was selected for its suitable features. It is worth noting that the purpose of this study was not to design the most accurate DR screening network, but to demonstrate the effect of the SOP of DR and the visualization of the revised ResNet-50 model. The results provided an insight to revise the structure of CNNs using the visualization tool.
    MeSH term(s) Humans ; Diabetic Retinopathy/diagnosis ; Fundus Oculi ; Mass Screening/methods ; Calibration ; Diabetes Mellitus
    Language English
    Publishing date 2023-04-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041484-5
    ISSN 1471-2105 ; 1471-2105
    ISSN (online) 1471-2105
    ISSN 1471-2105
    DOI 10.1186/s12859-023-05293-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Cu/MgO Reverse Water Gas Shift Catalyst with Unique CO

    Tsai, Ding-Huei / Wu, Tung-Ta / Lin, Hung-Chin / Chueh, Lu-Yu / Lin, Kun-Han / Yu, Wen-Yueh / Pan, Yung-Tin

    Chemistry, an Asian journal

    2024  Volume 19, Issue 6, Page(s) e202300955

    Abstract: Activation of inert ... ...

    Abstract Activation of inert CO
    Language English
    Publishing date 2024-02-26
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2233006-9
    ISSN 1861-471X ; 1861-4728
    ISSN (online) 1861-471X
    ISSN 1861-4728
    DOI 10.1002/asia.202300955
    Database MEDical Literature Analysis and Retrieval System OnLINE

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