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  1. Article: [Clinical and genetic analysis of ten Chinese pedigrees affected with 7q11.23 duplication syndrome].

    Shi, Panlai / Liu, Yongchao / Hou, Yaqin / Chen, Duo / Kong, Xiangdong

    Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics

    2024  Volume 41, Issue 2, Page(s) 140–144

    Abstract: Objective: To analyze the clinical and genetic characteristics of ten Chinese pedigrees affected with 7q11.23 duplication syndrome.: Methods: From December 2017 to January 2022, ten pedigrees diagnosed with 7q11.23 duplication syndrome at the First ... ...

    Abstract Objective: To analyze the clinical and genetic characteristics of ten Chinese pedigrees affected with 7q11.23 duplication syndrome.
    Methods: From December 2017 to January 2022, ten pedigrees diagnosed with 7q11.23 duplication syndrome at the First Affiliated Hospital of Zhengzhou University were enrolled as the study subjects. Clinical data of all subjects were collected, and some had subjected to copy number variation sequencing or single nucleotide polymorphism array to analyze the pattern of inheritance.
    Results: The probands had included six fetuses and four adolescents. Four of the six prenatal cases showed abnormal ultrasound indicators, including three with soft indicators and one with abnormal fetal structural development. The clinical phenotype of the four adolescent cases had included mental retardation, delayed language development, and attention deficit hyperactivity disorder. The size of the copy number variations had ranged from 1.31 to 1.42 Mb, involving the classic region of 7q11.23 duplication syndrome. Of these, five cases had undergone parental origin testing, three cases were de novo, and two were hereditary.
    Conclusion: Individuals with 7q11.23 duplication syndrome may show substantial clinical phenotypic heterogeneity, hence the affected families should be provided with pre-pregnancy consultation and reproductive guidance.
    MeSH term(s) Pregnancy ; Female ; Adolescent ; Humans ; DNA Copy Number Variations ; Pedigree ; Intellectual Disability/genetics ; Syndrome ; China
    Language Chinese
    Publishing date 2024-02-05
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1003-9406
    ISSN 1003-9406
    DOI 10.3760/cma.j.cn511374-20221118-00799
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  2. Article ; Online: Violence against nurses by patients and visitors in the emergency department: An integrative review.

    Hou, Yongchao / Corbally, Melissa / Timmins, Fiona

    Journal of advanced nursing

    2023  Volume 80, Issue 2, Page(s) 430–445

    Abstract: Aim: This integrative review explored violence against emergency nurses by patients/visitors, examining its nature, contributing factors and consequences.: Design: Integrative review.: Data sources: Articles were obtained from PubMed, CINAHL, ... ...

    Abstract Aim: This integrative review explored violence against emergency nurses by patients/visitors, examining its nature, contributing factors and consequences.
    Design: Integrative review.
    Data sources: Articles were obtained from PubMed, CINAHL, EMBASE, Web of Science and PsycInfo databases, up until December 2021.
    Review methods: 26 articles were reviewed, evaluating study quality with the Crowe Critical Appraisal Tool and synthesizing conclusions through theme development and coding.
    Results: This review delves into the issue of violence perpetrated against emergency nurses by patients and visitors. It elucidates three overarching themes: the nature of violence, the contributing factors and the consequences of such acts.
    Conclusion: The findings inform healthcare policy for the development of prevention approaches while identifying research gaps and emphasizing the need for alternative study designs and methodologies.
    Impact: This review has implications for nursing practice, policymaking and research, emphasizing the need for stakeholder engagement and tailored interventions for at-risk emergency nurses.
    No patient or public contribution: This project was an integrative review of the literature therefore no patient or public contribution was necessary.
    What already is known: Violence by patients and visitors in healthcare settings, especially in emergency departments, has garnered considerable attention.
    What this paper adds: This review specifically examines violence-targeting emergency department nurses from patients and visitors, assessing its characteristics, contributing factors and consequences.
    Implications for practice/policy: The findings will guide stakeholder engagement in developing interventions to support vulnerable emergency nurses.
    MeSH term(s) Humans ; Violence ; Patients ; Emergency Service, Hospital ; Visitors to Patients ; Policy Making ; Workplace Violence/prevention & control
    Language English
    Publishing date 2023-09-01
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 197634-5
    ISSN 1365-2648 ; 0309-2402
    ISSN (online) 1365-2648
    ISSN 0309-2402
    DOI 10.1111/jan.15837
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  3. Article ; Online: Violence against nurses by patients and visitors in the emergency department: A concept analysis.

    Hou, Yongchao / Corbally, Melissa / Timmins, Fiona

    Journal of nursing management

    2022  Volume 30, Issue 6, Page(s) 1688–1699

    Abstract: Aim: This analysis investigates the concept of violence against nurses by patients and visitors in the emergency department. It aims to differentiate, clarify, and clearly identify this specific concept, which will facilitate more apt measurement and ... ...

    Abstract Aim: This analysis investigates the concept of violence against nurses by patients and visitors in the emergency department. It aims to differentiate, clarify, and clearly identify this specific concept, which will facilitate more apt measurement and reporting, ultimately to contribute violence reduction measures.
    Background: Due to contextual factors, occupational risk and patient characteristics, violence against nurses by patients and visitors in the emergency department varies from other types of violence against other health care staff.
    Methods: This study employed Walker and Avant's concept analysis technique.
    Results: The analysis found that violence against nurses by patients and visitors in the emergency department is primarily an occurrence of interpersonal violence based on the working relationship, whereby the patient and/or visitor becomes an assailant, and a nurse becomes a target in the absence of capable guardianship. There is also an intentional use of physical force or power, which results in or has a high chance of causing harm.
    Conclusion: A clearer understanding of the antecedents, attributes, and consequences of violence against nurses by patients and visitors arising from this concept analysis provides a framework that will assist in the understanding, measurement, reporting, and prevention of violence and inform future research.
    Implications for nursing management: Nursing managers are encouraged to adopt strategies that act on the factors related to attributes and antecedents that will serve to reduce the occurrence of intentional violent acts.
    MeSH term(s) Aggression ; Emergency Service, Hospital ; Humans ; Violence/prevention & control ; Workplace Violence/prevention & control
    Language English
    Publishing date 2022-07-05
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1162321-4
    ISSN 1365-2834 ; 0966-0429
    ISSN (online) 1365-2834
    ISSN 0966-0429
    DOI 10.1111/jonm.13721
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  4. Article ; Online: Echocardiographic Image of a Cannula in the Inferior Vena Cava After Decannulation of Venoarterial Extracorporeal Membrane Oxygenation.

    Cui, Yongchao / Yang, Feng / Hou, Xiaotong

    Chest

    2021  Volume 160, Issue 5, Page(s) e527–e530

    MeSH term(s) Adolescent ; Anticoagulants/administration & dosage ; Catheterization, Peripheral/adverse effects ; Catheterization, Peripheral/instrumentation ; Catheterization, Peripheral/methods ; Diagnosis, Differential ; Dyspnea/diagnosis ; Dyspnea/etiology ; Echocardiography/methods ; Extracorporeal Membrane Oxygenation/adverse effects ; Extracorporeal Membrane Oxygenation/methods ; Femoral Artery/surgery ; Humans ; Male ; Myocarditis/diagnosis ; Myocarditis/physiopathology ; Myocarditis/therapy ; Treatment Outcome ; Vena Cava, Inferior/diagnostic imaging ; Venous Thrombosis/diagnosis ; Venous Thrombosis/drug therapy ; Venous Thrombosis/etiology
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2021-11-07
    Publishing country United States
    Document type Case Reports ; Journal Article ; Video-Audio Media
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2020.11.077
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  5. Article ; Online: Optimization Model for Uncertain Statistics Based on an Analytic Hierarchy Process

    Yongchao Hou

    Mathematical Problems in Engineering, Vol

    2014  Volume 2014

    Keywords Mathematics ; QA1-939 ; Science ; Q ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Technology ; T
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Hindawi Publishing Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Optimization Model for Uncertain Statistics Based on an Analytic Hierarchy Process

    Yongchao Hou

    Mathematical Problems in Engineering, Vol

    2014  Volume 2014

    Keywords Mathematics ; QA1-939 ; Science ; Q ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Technology ; T
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Hindawi Publishing Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Optimization Model for Uncertain Statistics Based on an Analytic Hierarchy Process

    Yongchao Hou

    Mathematical Problems in Engineering, Vol

    2014  Volume 2014

    Keywords Mathematics ; QA1-939 ; Science ; Q ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Technology ; T
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Hindawi Publishing Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Spontaneous Echo Contrast Mimicking Left Ventricular Thrombus in a Patient on Extracorporeal Membrane Oxygenation Support.

    Cui, Yongchao / Wang, Rui / Yang, Feng / Hou, Xiaotong

    Chest

    2021  Volume 159, Issue 6, Page(s) e437–e439

    MeSH term(s) Artifacts ; Cardiac Valve Annuloplasty/adverse effects ; Cardiac Valve Annuloplasty/methods ; Coronary Artery Bypass/adverse effects ; Coronary Artery Bypass/methods ; Coronary Artery Disease/diagnosis ; Coronary Artery Disease/surgery ; Diagnosis, Differential ; Echocardiography, Transesophageal/methods ; Extracorporeal Membrane Oxygenation/adverse effects ; Extracorporeal Membrane Oxygenation/methods ; Hemodynamic Monitoring/methods ; Humans ; Male ; Middle Aged ; Mitral Valve Insufficiency/diagnosis ; Mitral Valve Insufficiency/surgery ; Postoperative Complications/diagnosis ; Postoperative Complications/therapy ; Regional Blood Flow ; Thrombosis/diagnosis ; Ventricular Dysfunction, Left/diagnosis
    Language English
    Publishing date 2021-06-07
    Publishing country United States
    Document type Case Reports ; Journal Article ; Video-Audio Media
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2020.06.090
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  9. Article: Associations Between Single Nucleotide Polymorphisms of Hypoxia-Related Genes and Capsule Formation in Hepatocellular Carcinoma.

    Chen, Shanshan / Duan, Youjia / Zhang, Yongchao / Cheng, Long / Cai, Liang / Hou, Xiaopu / Li, Wei

    Journal of hepatocellular carcinoma

    2023  Volume 10, Page(s) 1785–1797

    Abstract: Purpose: Tumor capsule is an independent prognostic factor for patients with hepatocellular carcinoma (HCC) and used increasingly to guide clinical decision-making. Considering the genetic complexity for capsule formation and its potential association ... ...

    Abstract Purpose: Tumor capsule is an independent prognostic factor for patients with hepatocellular carcinoma (HCC) and used increasingly to guide clinical decision-making. Considering the genetic complexity for capsule formation and its potential association with hypoxia, the significance of the polymorphisms of hypoxia-related genes in capsule formation and HCC prognosis remains to be elucidated.
    Patients and methods: Peripheral blood samples from HCC patients were collected in this study. Single nucleotide polymorphism (SNP) genotyping was conducted by the iPLEX chemistry on a matrix-assisted laser desorption/ionization time-of-flight mass spectrometer (Sequenom, Inc.). The demographic and clinical data for the patients were obtained through medical chart review and/or consultation with the treating physicians. SPSS 25.0, R 4.1.1, and PLINK toolset were used to perform statistical analysis.
    Results: A total of 183 patients were enrolled, including 88 patients assigned to the capsule group and 95 to the non-capsule group. SLC2A1 rs841858 T allele, SLC2A1 rs2297977 T allele, STAT1 rs1547550 C allele, and STAT1 rs34997637 G allele were associated with significantly increased risk of capsule formation. The genotypes of SLC2A1 rs841858, SLC2A1 rs2297977, STAT1 rs34997637, and STAT1 rs1914408 were significantly associated with the formation of HCC capsule. The polymorphisms of STAT1 rs2066802, STAT1 rs12693591, and HIF1A rs2057482 showed close relationship with the prognosis of HCC patients in the capsule group, while the genotype distributions of CTNNB1 rs4135385, IFNG rs1861494, and SERPINE1 rs2227631 were closely related to the survival of patients in the non-capsule group. Further haplotype analysis suggested that SLC2A1 block 1 and STAT1 block 2 were related to the susceptibility of HCC capsule.
    Conclusion: The polymorphisms of the hypoxia-related genes (HIF1A, SERPINE1, IFNG, STAT1, CTNNB1, and SLC2A1) were correlated with the formation of HCC capsule. Several SNPs in these genes also showed association with HCC prognosis except SLC2A1. Further functional studies are warranted to explore the underlying mechanisms.
    Language English
    Publishing date 2023-10-10
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2780784-8
    ISSN 2253-5969
    ISSN 2253-5969
    DOI 10.2147/JHC.S417830
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  10. Article: Experimental Study on the Time-Dependent Characteristics of MLPS Transparent Soil Strength.

    Que, Xinzhe / Jin, Zhao / Hou, Yixuan / Zhou, Yongchao / Zhang, Yiping

    Materials (Basel, Switzerland)

    2022  Volume 15, Issue 14

    Abstract: The time-dependent characteristics of transparent soil strength, composed of magnesium lithium phyllosilicate, is important for applying a thixotropic clay surrogate. The gas injection method was employed to obtain the strength, represented as cracking ... ...

    Abstract The time-dependent characteristics of transparent soil strength, composed of magnesium lithium phyllosilicate, is important for applying a thixotropic clay surrogate. The gas injection method was employed to obtain the strength, represented as cracking pressure, which was then correlated to variables including rest time, disturbance time, and recovery time. Three concentrations (3, 4, and 5%) were tested. The results show that the strength was directly proportional to the rest time, recovery time, and concentration while the disturbance time reversed. The calculated limit strengths for 3%, 4%, and 5% transparent soils were 3.831 kPa, 8.849 kPa, and 12.048 kPa, respectively. Experimental data also showed that the residual strength for higher concentration transparent soil was more significant than the lower ones. The elastic property immediately generated partial strength recovery after disturbance, while the viscosity property resulted in a slow recovery stage similar to the rest stage. The strength recovery rate was also sensitive to concentration. Furthermore, the strength with 3%, 4%, and 5% concentrations could regain limit values after sufficient recovery, which were calculated as 4.303 kPa, 8.255 kPa, and 14.884 kPa, respectively.
    Language English
    Publishing date 2022-07-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma15144990
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