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  1. Article ; Online: Successful treatment of IgG4-related disease with tocilizumab monotherapy.

    Akiyama, Mitsuhiro / Hayashi, Yutaro / Suzuki, Koji / Takeuchi, Tsutomu / Kaneko, Yuko

    Autoimmunity reviews

    2023  Volume 22, Issue 4, Page(s) 103296

    MeSH term(s) Humans ; Immunoglobulin G4-Related Disease/drug therapy ; Antibodies, Monoclonal, Humanized/therapeutic use ; Antirheumatic Agents ; Treatment Outcome
    Chemical Substances tocilizumab (I031V2H011) ; Antibodies, Monoclonal, Humanized ; Antirheumatic Agents
    Language English
    Publishing date 2023-02-11
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2144145-5
    ISSN 1873-0183 ; 1568-9972
    ISSN (online) 1873-0183
    ISSN 1568-9972
    DOI 10.1016/j.autrev.2023.103296
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    Zs.A 5913: Show issues Location:
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  2. Article ; Online: Comparison of the short-term efficacy and safety of bipolar transurethral electro vaporization and holmium laser enucleation of the prostate for moderate and large benign prostatic enlargement.

    Hayashi, Yutaro / Yoneyama, Shuko / Takizawa, Akitoshi / Kobayashi, Kazuki / Ito, Hiroki

    BMC urology

    2023  Volume 23, Issue 1, Page(s) 50

    Abstract: Background: To compare the efficacy and safety of bipolar transurethral vaporization of the prostate (B-TUVP) with holmium laser enucleation of the prostate (HoLEP) for moderate [prostate volume (PV) 30-80 ml] and large (≥ 80 ml) benign prostatic ... ...

    Abstract Background: To compare the efficacy and safety of bipolar transurethral vaporization of the prostate (B-TUVP) with holmium laser enucleation of the prostate (HoLEP) for moderate [prostate volume (PV) 30-80 ml] and large (≥ 80 ml) benign prostatic enlargement (BPE).
    Materials and methods: Male patients with lower urinary tract symptom (LUTS) or urinary retention who underwent B-TUVP or HoLEP treatment in two regional centers were respectively enrolled. Patient characteristics and treatment outcomes were retrospectively compared between B-TUVP and HoLEP.
    Results: In patients with moderate and large prostate volume,B-TUVP showed shorter operative time (P < 0.001) and less hemoglobin decrease (P < 0.001) than in HoLEP. In uncatheterised patients, voiding symptoms and patients' quality of life improved after B-TUVP and HoLEP, but these improvement rates were consistently bigger in HoLEP than in B-TUVP. In catheterised patients, the rate of achieving catheter-free status after surgery was higher in HoLEP than in B-TUVP for patients with PV > 80 ml.(P < 0.001) The incidence of postoperative fever was higher in B-TUVP than in HoLEP for patients with PV 30-80 ml (P < 0.001) but not for those with PV > 80 ml.(P=0.08) The Incidence of postoperative stress incontinence(SUI) was higher in HoLEP than in B-TUVP for patients with moderate and large prostate volume.
    Conclusions: There are few studies that investigated the short-term efficacy and safety of second-generation B-TUVP in comparison with HoLEP for moderate and large BPE. Improvement in LUTS and achievement of catheter-free status were predominant in HoLEP, and these outcomes were more prominent in patients with large BPE of PV > 80 ml. However, B-TUVP resulted in less blood loss, shorter operative duration, and less SUI suggesting that B-TUVP is also well-tolerated surgical modality.
    MeSH term(s) Humans ; Male ; Laser Therapy/methods ; Lasers, Solid-State/therapeutic use ; Lower Urinary Tract Symptoms/surgery ; Prostate/surgery ; Prostatic Hyperplasia/surgery ; Quality of Life ; Retrospective Studies ; Transurethral Resection of Prostate/methods ; Treatment Outcome ; Volatilization
    Language English
    Publishing date 2023-03-29
    Publishing country England
    Document type Comparative Study ; Journal Article
    ZDB-ID 2059857-9
    ISSN 1471-2490 ; 1471-2490
    ISSN (online) 1471-2490
    ISSN 1471-2490
    DOI 10.1186/s12894-023-01215-8
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  3. Article: Conservative management of pubertal segmental testicular infarction associated with epididymitis.

    Nishio, Hidenori / Mizuno, Kentaro / Matsumoto, Daisuke / Nakane, Akihiro / Yasui, Takahiro / Hayashi, Yutaro

    Urology case reports

    2023  Volume 46, Page(s) 102324

    Abstract: Urgent scrotal exploration is performed for segmental testicular infarction (STI) because malignant testicular tumors cannot be ruled out even when STI is suspected on color Doppler ultrasound (US). This report describes the case of a 14-year-old boy who ...

    Abstract Urgent scrotal exploration is performed for segmental testicular infarction (STI) because malignant testicular tumors cannot be ruled out even when STI is suspected on color Doppler ultrasound (US). This report describes the case of a 14-year-old boy who was successfully diagnosed with STI associated with epididymitis using color Doppler US to avoid radical orchiectomy. To our knowledge, this is the first report of STI being diagnosed during puberty and managed using color Doppler US and contrast-enhanced magnetic resonance imaging-guided conservative treatment.
    Language English
    Publishing date 2023-01-11
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2745459-9
    ISSN 2214-4420
    ISSN 2214-4420
    DOI 10.1016/j.eucr.2023.102324
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  4. Article: Ureterocele prolapse eliciting unusual patient behavior to control intermittent voiding.

    Nishio, Hidenori / Mizuno, Kentaro / Matsumoto, Daisuke / Yasui, Takahiro / Hayashi, Yutaro

    Urology case reports

    2022  Volume 46, Page(s) 102295

    Abstract: Ureterocele prolapse, an unusual but distinctive finding, may cause voiding difficulty. A 6-year-old male patient was referred to our hospital after his mother discovered that he tapped his lower abdomen when his urinary stream was interrupted during ... ...

    Abstract Ureterocele prolapse, an unusual but distinctive finding, may cause voiding difficulty. A 6-year-old male patient was referred to our hospital after his mother discovered that he tapped his lower abdomen when his urinary stream was interrupted during voiding. Voiding cystourethrography indicated a ureterocele prolapse causing the intermittency of voiding; therefore, transvesicoscopic ureteral reimplantation with ureterocelectomy was performed and the voiding consequently improved. However, this condition would not have been diagnosed had the unusual voiding behavior gone unnoticed. Therefore, diagnosing congenital bladder obstructions could be challenging if a patient adapts to a voiding difficulty.
    Language English
    Publishing date 2022-11-30
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2745459-9
    ISSN 2214-4420
    ISSN 2214-4420
    DOI 10.1016/j.eucr.2022.102295
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  5. Article: Geochemical Modeling of Heavy Metal Removal from Acid Mine Drainage in an Ethanol-Supplemented Sulfate-Reducing Column Test.

    Oyama, Keishi / Hayashi, Kentaro / Masaki, Yusei / Hamai, Takaya / Fuchida, Shigeshi / Takaya, Yutaro / Tokoro, Chiharu

    Materials (Basel, Switzerland)

    2023  Volume 16, Issue 3

    Abstract: A passive treatment process using sulfate-reducing bacteria (SRB) is known to be effective in removing heavy metals from acid mine drainage (AMD), though there has been little discussion of the mechanism involved to date. In this work, a sulfate-reducing ...

    Abstract A passive treatment process using sulfate-reducing bacteria (SRB) is known to be effective in removing heavy metals from acid mine drainage (AMD), though there has been little discussion of the mechanism involved to date. In this work, a sulfate-reducing column test was carried out using supplementary ethanol as an electron donor for microorganisms, and the reaction mechanism was examined using geochemical modeling and X-ray absorption fine structure (XAFS) analysis. The results showed that Cu was readily removed from the AMD on the top surface of the column (0-0.2 m), while Zn and Cd depletion was initiated in the middle of the column (0.2-0.4 m), where sulfide formation by SRB became noticeable. Calculations by a developed geochemical model suggested that ethanol decomposition by aerobic microbes contributed to the reduction of Cu, while sulfide produced by SRB was the major cause of Zn and Cd removal. XAFS analysis of column residue detected ZnS, ZnSO
    Language English
    Publishing date 2023-01-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma16030928
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  6. Article ; Online: Combination of robot-assisted laparoscopic pyeloplasty for lower moiety ureteropelvic junction obstruction in a partial duplex system and percutaneous endoscopic surgery for renal calculi reusing the port for robotic pyeloplasty.

    Nishio, Hidenori / Mizuno, Kentaro / Matsumoto, Daisuke / Tozawa, Keiichi / Yasui, Takahiro / Hayashi, Yutaro

    IJU case reports

    2023  Volume 6, Issue 6, Page(s) 390–393

    Abstract: Introduction: Ureteropelvic junction obstruction is often associated with renal calculus formation. However, there is no report of using robot-assisted laparoscopic pyeloplasty combined with percutaneous endoscopic surgery for ureteropelvic junction ... ...

    Abstract Introduction: Ureteropelvic junction obstruction is often associated with renal calculus formation. However, there is no report of using robot-assisted laparoscopic pyeloplasty combined with percutaneous endoscopic surgery for ureteropelvic junction obstruction and renal calculi in a partial duplex system.
    Case presentation: A 19-year-old female patient with lower moiety ureteropelvic junction obstruction and renal calculi in a partial duplex system was referred to our hospital because of left lumbar pain, left acute pyelonephritis, and an increase in left renal calculi during follow-up at the referral hospital. To prevent the complication of percutaneous nephrolithotripsy following pyeloplasty, robot-assisted laparoscopic pyeloplasty combined with percutaneous endoscopic surgery was performed. Two years after surgery, the patient reported no left lumbar pain.
    Conclusion: The combination of robot-assisted laparoscopic pyeloplasty and percutaneous endoscopic surgery can be proposed as a safe and less-invasive treatment option for ureteropelvic junction obstruction and renal calculi in a partial duplex system.
    Language English
    Publishing date 2023-09-03
    Publishing country Australia
    Document type Case Reports
    ISSN 2577-171X
    ISSN (online) 2577-171X
    DOI 10.1002/iju5.12630
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  7. Article: [A Case of Dedifferentiated Liposarcoma of the Spermatic Cord].

    Ishibashi, Yukari / Ninomiya, Sahoko / Hayashi, Yutaro / Fusayasu, Syusei / Suzuki, Koutaro

    Hinyokika kiyo. Acta urologica Japonica

    2022  Volume 68, Issue 1, Page(s) 17–21

    Abstract: A 52-year-old man was referred to our hospital for evaluation of painless right scrotal swelling persisting for 3 months. Palpation detected swelling and induration centered on the head of the upper epididymis, and ultrasonography revealed a blood-filled ...

    Abstract A 52-year-old man was referred to our hospital for evaluation of painless right scrotal swelling persisting for 3 months. Palpation detected swelling and induration centered on the head of the upper epididymis, and ultrasonography revealed a blood-filled nodular mass at the same site continuing to the spermatic cord. No abnormalities were observed in the bilateral testes. Blood tests were negative for tumor markers such as α fetoprotein and human chorionic gonadotropin-β. Right radical inguinal orchiectomy was performed, and the pathological diagnosis was dedifferentiated liposarcoma of the spermatic cord. Although the spermatic cord stump was negative, the peri-spermatic cord stump, which had an exfoliated surface, was positive. No residual tumor was found on magnetic resonance imaging, but the tumor was suspected to remain. Thus, after approximately 1month, the tissue around the spermatic cord was resected. Eight months after the initial operation, no recurrence was observed. Here, we report a case of dedifferentiated liposarcoma of the spermatic cord, which is relatively rare, and review the related literature.
    MeSH term(s) Genital Neoplasms, Male/diagnostic imaging ; Genital Neoplasms, Male/surgery ; Humans ; Liposarcoma/diagnostic imaging ; Liposarcoma/surgery ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Orchiectomy ; Spermatic Cord/diagnostic imaging ; Spermatic Cord/surgery
    Language Japanese
    Publishing date 2022-02-03
    Publishing country Japan
    Document type Case Reports ; Journal Article
    ZDB-ID 604331-8
    ISSN 0018-1994
    ISSN 0018-1994
    DOI 10.14989/ActaUrolJap_68_1_17
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    Zs.A 411: Show issues Location:
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  8. Article ; Online: Preventability of Early Versus Late Hospital Readmissions.

    Nagasaki, Kazuya / Akiyama, Yutaro / Hayashi, Mikio / Mori, Hideki

    Annals of internal medicine

    2019  Volume 170, Issue 3, Page(s) 219

    MeSH term(s) Cohort Studies ; Humans ; Patient Readmission ; Time Factors
    Language English
    Publishing date 2019-03-18
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/L18-0609
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  9. Article: Asymmetric Michael Reaction of Malononitrile and α,β-Unsaturated Aldehydes Catalyzed by Diarylprolinol Silyl Ether

    Hayashi, Yujiro / Hatano, Yutaro / Mori, Naoki

    Synlett

    2022  Volume 33, Issue 18, Page(s) 1831–1836

    Abstract: An asymmetric Michael reaction of malononitrile and α,β-unsaturated aldehydes catalyzed by a diarylprolinol silyl ether was developed. Michael products were obtained in good yields and with excellent enantioselectivities without the formation of ... ...

    Abstract An asymmetric Michael reaction of malononitrile and α,β-unsaturated aldehydes catalyzed by a diarylprolinol silyl ether was developed. Michael products were obtained in good yields and with excellent enantioselectivities without the formation of overreaction products. As a malononitrile moiety can be transformed into an alkoxy or amino carbonyl moiety by oxidative transformation, α-chiral esters or amides with all-carbon quaternary centers can be synthesized with excellent enantioselectivities.
    Keywords organocatalysis ; Michael reaction ; asymmetric catalysis ; diarylprolinol silyl ethers ; malononitrile ; carbon quaternary centers
    Language English
    Publishing date 2022-05-08
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2042012-2
    ISSN 1437-2096 ; 0936-5214
    ISSN (online) 1437-2096
    ISSN 0936-5214
    DOI 10.1055/a-1846-5007
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  10. Article ; Online: BMP10 expression in the adult rat central nervous system.

    Ogawa, Chikara / Mikawa, Sumiko / Li, Shuo / Hayashi, Yutaro / Masumoto, Kazuma / Sato, Kohji

    Journal of chemical neuroanatomy

    2022  Volume 121, Page(s) 102084

    Abstract: Bone morphogenetic protein 10 (BMP10), is a member of the transforming growth factor β (TGFβ) superfamily. Although BMP10 plays pivotal roles during development, including vascular development and cardiogenesis, little information is available for BMP10 ... ...

    Abstract Bone morphogenetic protein 10 (BMP10), is a member of the transforming growth factor β (TGFβ) superfamily. Although BMP10 plays pivotal roles during development, including vascular development and cardiogenesis, little information is available for BMP10 expression in the central nervous system (CNS). We, thus, investigated BMP10 expression in the adult rat CNS using immunohistochemistry. BMP10 was intensely expressed in most neurons and their axons. Furthermore, we found that astrocytes and ependymal cells also express BMP10 protein. These data indicate that BMP10 is widely expressed throughout the adult CNS, and this abundant expression strongly supports the idea that BMP10 also plays important roles in the adult CNS.
    MeSH term(s) Animals ; Bone Morphogenetic Proteins/metabolism ; Brain/metabolism ; Central Nervous System ; Neurons/metabolism ; Rats ; Rats, Wistar
    Chemical Substances Bone Morphogenetic Proteins
    Language English
    Publishing date 2022-02-16
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639443-7
    ISSN 1873-6300 ; 0891-0618
    ISSN (online) 1873-6300
    ISSN 0891-0618
    DOI 10.1016/j.jchemneu.2022.102084
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    Zs.A 2363: Show issues Location:
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