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  1. Article ; Online: Sodium Glucose Co-Transporter 2 Inhibition Following Acute Myocardial Infarction: The DAPA-MI and EMPACT-MI Trials.

    Peikert, Alexander / Vaduganathan, Muthiah

    JACC. Heart failure

    2024  

    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Editorial
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2024.01.019
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  2. Article ; Online: Closer to FREEDOM From Uncertainty.

    Vaduganathan, Muthiah / Bikdeli, Behnood

    Journal of the American College of Cardiology

    2023  Volume 81, Issue 18, Page(s) 1763–1765

    MeSH term(s) Humans ; Uncertainty ; Anticoagulants ; Enoxaparin ; Freedom ; Pyridones ; Venous Thromboembolism
    Chemical Substances Anticoagulants ; Enoxaparin ; Pyridones
    Language English
    Publishing date 2023-05-17
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2023.03.407
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1846: Show issues Location:
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    Zs.MO 196: Show issues

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  3. Article ; Online: Fulfilling the Promise of Telemonitoring in Heart Failure.

    Gupta, Prerna / Vaduganathan, Muthiah

    Journal of cardiac failure

    2023  Volume 29, Issue 12, Page(s) 1655–1656

    MeSH term(s) Humans ; Heart Failure/diagnosis ; Heart Failure/therapy ; Telemedicine ; Monitoring, Ambulatory
    Language English
    Publishing date 2023-07-11
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1281194-4
    ISSN 1532-8414 ; 1071-9164
    ISSN (online) 1532-8414
    ISSN 1071-9164
    DOI 10.1016/j.cardfail.2023.06.018
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    Zs.A 4340: Show issues Location:
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  4. Article ; Online: Implementation Approaches in Heart Failure With Mildly Reduced and Preserved Ejection Fraction.

    Bhatt, Ankeet S / Filippatos, Gerasimos / Vaduganathan, Muthiah

    JACC. Heart failure

    2024  Volume 12, Issue 4, Page(s) 628–630

    MeSH term(s) Humans ; Heart Failure/therapy ; Stroke Volume ; Hospitalization ; Ventricular Dysfunction, Left ; Ventricular Function, Left
    Language English
    Publishing date 2024-02-26
    Publishing country United States
    Document type Editorial
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2024.01.013
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  5. Article ; Online: When and how? Two simple questions to determine cancer status and inform therapeutic decisions and trial design in heart failure.

    Ameri, Pietro / Vaduganathan, Muthiah

    European journal of heart failure

    2023  Volume 25, Issue 10, Page(s) 1868–1870

    MeSH term(s) Humans ; Heart Failure/drug therapy ; Neoplasms
    Language English
    Publishing date 2023-09-19
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1483672-5
    ISSN 1879-0844 ; 1388-9842
    ISSN (online) 1879-0844
    ISSN 1388-9842
    DOI 10.1002/ejhf.3035
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    Zs.A 5299: Show issues Location:
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  6. Article ; Online: Glucagon-Like Peptide-1 Receptor Agonists in Heart Failure: STEPping Across the Ejection Fraction Divide.

    Vaduganathan, Muthiah / Ostrominski, John W

    Journal of the American College of Cardiology

    2023  Volume 82, Issue 22, Page(s) 2097–2100

    MeSH term(s) Humans ; Glucagon-Like Peptide-1 Receptor/agonists ; Stroke Volume ; Heart Failure/drug therapy ; Hypoglycemic Agents ; Diabetes Mellitus, Type 2
    Chemical Substances Glucagon-Like Peptide-1 Receptor ; Hypoglycemic Agents
    Language English
    Publishing date 2023-10-08
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2023.09.812
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    Zs.MO 196: Show issues

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  7. Article ; Online: Accelerated Risk-Based Implementation of Guideline-Directed Medical Therapy for Type 2 Diabetes and Chronic Kidney Disease.

    Neuen, Brendon L / Tuttle, Katherine R / Vaduganathan, Muthiah

    Circulation

    2024  Volume 149, Issue 16, Page(s) 1238–1240

    MeSH term(s) Humans ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/epidemiology ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/drug therapy ; Renal Insufficiency, Chronic/epidemiology
    Language English
    Publishing date 2024-04-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.123.068524
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    Ui IV Zs.60: Show issues Location:
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  8. Article ; Online: Interpreting Nonrandomized Evidence for Clinical Decision Making in Cardio-Oncology.

    Chatur, Safia / Fu, Edouard / Vaduganathan, Muthiah

    JACC. CardioOncology

    2023  Volume 5, Issue 3, Page(s) 329–331

    Language English
    Publishing date 2023-06-20
    Publishing country United States
    Document type Editorial
    ISSN 2666-0873
    ISSN (online) 2666-0873
    DOI 10.1016/j.jaccao.2023.05.003
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  9. Article ; Online: Chapter 2: Clinical and Mechanistic Potential of Sodium-Glucose Co-Transporter 2 (SGLT2) Inhibitors in Heart Failure with Preserved Ejection Fraction.

    Ostrominski, John W / Vaduganathan, Muthiah

    The American journal of medicine

    2023  Volume 137, Issue 2S, Page(s) S9–S24

    Abstract: Sodium-glucose co-transporter 2 inhibitors (SGLT2i) have emerged as an important approach for the treatment of heart failure in patients with or without diabetes. Although the precise mechanisms underpinning their clinical impact remain incompletely ... ...

    Abstract Sodium-glucose co-transporter 2 inhibitors (SGLT2i) have emerged as an important approach for the treatment of heart failure in patients with or without diabetes. Although the precise mechanisms underpinning their clinical impact remain incompletely resolved, mechanistic studies and insights from major clinical trials have demonstrated the impact of SGLT2 inhibitors on numerous cardio-renal-metabolic pathways of relevance to heart failure with preserved ejection fraction (HFpEF), which, in the contemporary era, constitutes approximately half of all patients with heart failure. Despite rates of morbidity and mortality that are commensurate with those of heart failure with reduced ejection fraction, disease-modifying therapies have comparatively been severely lacking. As such, HFpEF remains among the greatest unmet needs in cardiovascular medicine. Within the past decade, HFpEF has been established as a highly integrated disorder, involving not only the cardiovascular system, but also the lungs, kidneys, skeletal muscle, and adipose tissue. Given their multisystem impact, SGLT2i offer unique promise in addressing the complex pathophysiology of HFpEF, and in recent randomized controlled trials, were shown to significantly reduce heart failure events and cardiovascular death in patients with HFpEF. Herein, we discuss several proposed mechanisms of clinical benefit of SGLT2i in HFpEF.
    MeSH term(s) Humans ; Heart Failure ; Sodium-Glucose Transporter 2 Inhibitors/pharmacology ; Sodium-Glucose Transporter 2 Inhibitors/therapeutic use ; Sodium-Glucose Transporter 2/therapeutic use ; Stroke Volume ; Glucose/therapeutic use ; Sodium
    Chemical Substances Sodium-Glucose Transporter 2 Inhibitors ; Sodium-Glucose Transporter 2 ; Glucose (IY9XDZ35W2) ; Sodium (9NEZ333N27)
    Language English
    Publishing date 2023-05-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2023.04.035
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    Ua VI Zs.289: Show issues Location:
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  10. Article ; Online: The cardiovascular legacy of the COVID-19 pandemic.

    Bhatt, Ankeet S / Vaduganathan, Muthiah

    European heart journal

    2022  Volume 43, Issue 33, Page(s) 3179–3181

    MeSH term(s) COVID-19 ; Cardiovascular Diseases/epidemiology ; Cardiovascular System ; Humans ; Pandemics/prevention & control ; SARS-CoV-2
    Language English
    Publishing date 2022-06-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehac256
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