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  1. Article ; Online: Clearing the Air on Personal Interventions to Reduce Exposure to Wildfire Smoke.

    Laumbach, Robert J

    Annals of the American Thoracic Society

    2019  Volume 16, Issue 7, Page(s) 815–818

    MeSH term(s) Air Pollution/prevention & control ; Environmental Exposure/prevention & control ; Humans ; Linear Models ; Personal Protective Equipment ; Respiratory Protective Devices ; Smoke/adverse effects ; Survival Rate/trends ; United States ; Wildfires
    Chemical Substances Smoke
    Language English
    Publishing date 2019-05-29
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.201812-894PS
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Personal Interventions to Reduce Exposure to Outdoor Air Pollution.

    Laumbach, Robert J / Cromar, Kevin R

    Annual review of public health

    2021  Volume 43, Page(s) 293–309

    Abstract: Unhealthy levels of air pollution are breathed by billions of people worldwide, and air pollution is the leading environmental cause of death and disability globally. Efforts to reduce air pollution at its many sources have had limited success, and in ... ...

    Abstract Unhealthy levels of air pollution are breathed by billions of people worldwide, and air pollution is the leading environmental cause of death and disability globally. Efforts to reduce air pollution at its many sources have had limited success, and in many areas of the world, poor air quality continues to worsen. Personal interventions to reduce exposure to air pollution include avoiding sources, staying indoors, filtering indoor air, using face masks, and limiting physical activity when and where air pollution levels are elevated. The effectiveness of these interventions varies widely with circumstances and conditions of use. Compared with upstream reduction or control of emissions, personal interventions place burdens and risk of adverse unintended consequences on individuals. We review evidence regarding the balance of benefits and potential harms of personal interventions for reducing exposure to outdoor air pollution, which merit careful consideration before making public health recommendations with regard to who should use personal interventions and where, when, and how they should be used.
    MeSH term(s) Air Pollutants/analysis ; Air Pollutants/toxicity ; Air Pollution/prevention & control ; Air Pollution/statistics & numerical data ; Air Pollution, Indoor/prevention & control ; Air Pollution, Indoor/statistics & numerical data ; Humans
    Chemical Substances Air Pollutants
    Language English
    Publishing date 2021-12-22
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 760917-6
    ISSN 1545-2093 ; 0163-7525
    ISSN (online) 1545-2093
    ISSN 0163-7525
    DOI 10.1146/annurev-publhealth-052120-103607
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Engine on the Bus Goes Vroom, Vroom, Vroom!. And the Fumes on the Bus Go . . . ?

    Laumbach, Robert J

    American journal of respiratory and critical care medicine

    2015  Volume 191, Issue 12, Page(s) 1350–1352

    MeSH term(s) Air Pollutants/adverse effects ; Air Pollution/prevention & control ; Female ; Gasoline/statistics & numerical data ; Health Status ; Humans ; Male ; Motor Vehicles/statistics & numerical data ; Vehicle Emissions/prevention & control
    Chemical Substances Air Pollutants ; Gasoline ; Vehicle Emissions
    Language English
    Publishing date 2015-06-15
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.201504-0836ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Outdoor air pollutants and patient health.

    Laumbach, Robert J

    American family physician

    2010  Volume 81, Issue 2, Page(s) 175–180

    Abstract: Almost 160 million persons live in areas of the United States that exceed federal health-based air pollution standards. The two air pollutants that most commonly exceed standards are ozone and particulate matter. Ozone and particulate matter can harm ... ...

    Abstract Almost 160 million persons live in areas of the United States that exceed federal health-based air pollution standards. The two air pollutants that most commonly exceed standards are ozone and particulate matter. Ozone and particulate matter can harm anyone if levels are sufficiently elevated, but health risk from air pollution is greatest among vulnerable populations. Both ozone and particulate matter can cause pulmonary inflammation, decreased lung function, and exacerbation of asthma and chronic obstructive pulmonary disease. Particulate matter is also strongly associated with increased cardiovascular morbidity and mortality. Children, older adults, and other vulnerable persons may be sensitive to lower levels of air pollution. Persons who are aware of local air pollution levels, reported daily by the U.S. Environmental Protection Agency as the Air Quality Index, can take action to reduce exposure. These actions include simple measures to limit exertion and time spent outdoors when air pollution levels are highest, and to reduce the infiltration of outdoor air pollutants into indoor spaces.
    MeSH term(s) Adult ; Aged ; Air Pollutants/adverse effects ; Air Pollution/adverse effects ; Cardiovascular Diseases/chemically induced ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/prevention & control ; Child ; Environmental Health ; Environmental Monitoring/methods ; Epidemiological Monitoring ; Humans ; Inhalation Exposure/adverse effects ; Middle Aged ; Ozone/adverse effects ; Particulate Matter/adverse effects ; United States/epidemiology ; United States Environmental Protection Agency ; Vulnerable Populations/statistics & numerical data
    Chemical Substances Air Pollutants ; Particulate Matter ; Ozone (66H7ZZK23N)
    Language English
    Publishing date 2010-01-15
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 412694-4
    ISSN 1532-0650 ; 0002-838X ; 0572-3612
    ISSN (online) 1532-0650
    ISSN 0002-838X ; 0572-3612
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Real-World Effectiveness of Portable Air Cleaners in Reducing Home Particulate Matter Concentrations.

    Lu, Frederic T / Laumbach, Robert J / Legard, Alicia / Myers, Nirmala T / Black, Kathleen G / Ohman-Strickland, Pamela / Alimokhtari, Shahnaz / de Resende, Adriana / Calderón, Leonardo / Mainelis, Gediminas / Kipen, Howard M

    Aerosol and air quality research

    2023  Volume 24, Issue 1

    Abstract: Portable air cleaners (PACs) equipped with HEPA filters are gaining attention as cost-effective means of decreasing indoor particulate matter (PM) air pollutants and airborne viruses. However, the performance of PACs in naturalistic settings and spaces ... ...

    Abstract Portable air cleaners (PACs) equipped with HEPA filters are gaining attention as cost-effective means of decreasing indoor particulate matter (PM) air pollutants and airborne viruses. However, the performance of PACs in naturalistic settings and spaces beyond the room containing the PAC is not well characterized. We conducted a single-blinded randomized cross-over interventional study between November 2020 and May 2021 in the homes of adults who tested positive for COVID-19. The intervention was air filtration with PAC operated with the HEPA filter set installed ("filter" condition) versus removed ("sham" condition, i.e., control). Sampling was performed in 29 homes for two consecutive 24-hour periods in the primary room (containing the PAC) and a secondary room. PAC effectiveness, calculated as reductions in overall mean PM
    Language English
    Publishing date 2023-11-22
    Publishing country China (Republic : 1949- )
    Document type Journal Article
    ZDB-ID 2715139-6
    ISSN 2071-1409 ; 1680-8584
    ISSN (online) 2071-1409
    ISSN 1680-8584
    DOI 10.4209/aaqr.230202
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The effect of the indoor environment on wheeze- and sleep-related symptoms in young Indian children.

    Sastry, Jayagowri / Agawane, Shubhangi / Rajan, Mangala / Black, Kathleen / Laumbach, Robert / Ramagopal, Maya

    Lung India : official organ of Indian Chest Society

    2021  Volume 38, Issue 4, Page(s) 307–313

    Abstract: Background: Environmental exposures have a significant effect on respiratory and sleep symptoms in young children. Although the effect of air pollution on the respiratory symptoms in young children is well-established, less is known about the effect of ... ...

    Abstract Background: Environmental exposures have a significant effect on respiratory and sleep symptoms in young children. Although the effect of air pollution on the respiratory symptoms in young children is well-established, less is known about the effect of household environmental characteristics and practices on wheeze and sleep concerns.
    Aims: The aim of this pilot study is to explore the association between household environmental characteristics and practices with the symptoms of wheezing and sleep concerns in the past year in a convenience sample of young Indian children.
    Materials and methods: A detailed questionnaire about the child's home environment and respiratory and sleep symptoms was administered to the caregivers of 190 outpatients aged between 6 months and 5 years old at a teaching hospital.
    Results: Indoor environmental characteristics and cleaning techniques were analyzed for the association with wheeze and sleep disorders. Half (50%) of the cohort had the symptoms of wheezing and 21% had occasional or frequent sleep concerns. Sleeping with a stuffed toy was significantly associated with both wheezing and sleep concerns (P = 0.05).
    Conclusions: : Sleeping with a stuffed toy was a risk factor for wheeze and a risk factor for sleep disorders independent of wheeze.
    Language English
    Publishing date 2021-07-14
    Publishing country India
    Document type Journal Article
    ZDB-ID 2410801-7
    ISSN 0974-598X ; 0970-2113
    ISSN (online) 0974-598X
    ISSN 0970-2113
    DOI 10.4103/lungindia.lungindia_120_20
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  7. Article ; Online: Prevalence of Surface Contamination With SARS-CoV-2 in a Radiation Oncology Clinic.

    Jan, Imraan / Chen, Kenneth / Sayan, Mutlay / Uprety, Priyanka / Laumbach, Robert J / Ennis, Ronald D / Haffty, Bruce G

    JAMA oncology

    2020  Volume 6, Issue 10, Page(s) 1632–1634

    MeSH term(s) Betacoronavirus/isolation & purification ; Betacoronavirus/pathogenicity ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/epidemiology ; Coronavirus Infections/virology ; Humans ; Neoplasms/complications ; Neoplasms/epidemiology ; Neoplasms/radiotherapy ; Neoplasms/virology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/virology ; Prevalence ; Radiation Oncology/trends ; SARS-CoV-2 ; Surface Properties
    Keywords covid19
    Language English
    Publishing date 2020-08-27
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ISSN 2374-2445
    ISSN (online) 2374-2445
    DOI 10.1001/jamaoncol.2020.3552
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Vascular endothelial growth factor levels and bronchopulmonary dysplasia in preterm infants.

    Mariduena, Joseph / Ramagopal, Maya / Hiatt, Mark / Chandra, Shakuntala / Laumbach, Robert / Hegyi, Thomas

    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

    2020  Volume 35, Issue 8, Page(s) 1517–1522

    Abstract: Background: Vascular endothelial growth factor (VEGF) and its receptors (VEGFRs) regulate both vasculogenesis, the development of blood vessels from precursor cells, and angiogenesis, the formation of blood vessels from preexisting vessels. In the fetal ...

    Abstract Background: Vascular endothelial growth factor (VEGF) and its receptors (VEGFRs) regulate both vasculogenesis, the development of blood vessels from precursor cells, and angiogenesis, the formation of blood vessels from preexisting vessels. In the fetal lung, high-affinity receptors for VEGF are expressed mainly in alveolar epithelial cells and myocytes, suggesting a paracrine role for VEGF in modulating activities in adjacent vascular endothelium. Previous studies have shown that vascular growth is impaired in bronchopulmonary dysplasia (BPD).
    Objective: The goal of this study was to examine tracheal (T-VEGF) and gastric (G-VEGF) levels in premature infants in the first and third day of life and examine if these levels were associated with the development of BPD.
    Design/methods: Tracheal aspirates from intubated infants and gastric samples from others were obtained on postnatal days 1 (D1) and 3 (D3) from 43 preterm infants (<2000 g birth weight, ≤34 wks gestation). VEGF was quantified by a VEGF Elisa Kit. Demographic, clinical, and pulmonary outcome data were collected including information on respiratory support (oxygenation index (OI) and ventilatory index (VI)) and on the development of BPD, determined at 36 weeks PMA using NICHD criteria.
    Results: The mean birth weight was 1060 ± 379 g and gestational age 27.5 ± 2.8 wks. BPD was diagnosed in 26 infants who were less mature than the 17 controls without BPD. Day 1 and day 3T-VEGF concentrations did not correlate, but day 3 levels correlated with gestational age (
    Conclusions: BPD may be associated with low-serum VEGF levels during the first week of life. This finding is likely related to decreased expression in the lungs of the less mature infants, who are at the highest risk for BPD.
    MeSH term(s) Bronchopulmonary Dysplasia ; Female ; Gestational Age ; Humans ; Infant ; Infant, Newborn ; Infant, Premature/metabolism ; Pregnancy ; Vascular Endothelial Growth Factor A ; Vascular Endothelial Growth Factors
    Chemical Substances VEGFA protein, human ; Vascular Endothelial Growth Factor A ; Vascular Endothelial Growth Factors
    Language English
    Publishing date 2020-05-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2077261-0
    ISSN 1476-4954 ; 1057-0802 ; 1476-7058
    ISSN (online) 1476-4954
    ISSN 1057-0802 ; 1476-7058
    DOI 10.1080/14767058.2020.1760826
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  9. Article ; Online: Does diesel exhaust cause lung cancer (yet)?

    Laumbach, Robert J / Kipen, Howard M

    American journal of respiratory and critical care medicine

    2011  Volume 183, Issue 7, Page(s) 843–844

    MeSH term(s) Environmental Exposure/adverse effects ; Female ; Humans ; Incidence ; Lung Neoplasms/chemically induced ; Lung Neoplasms/epidemiology ; Male ; Occupational Exposure/adverse effects ; Occupational Health ; Risk Assessment ; Vehicle Emissions/toxicity
    Chemical Substances Vehicle Emissions
    Language English
    Publishing date 2011-04-06
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.201011-1870ED
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  10. Article ; Online: Respiratory health effects of air pollution: update on biomass smoke and traffic pollution.

    Laumbach, Robert J / Kipen, Howard M

    The Journal of allergy and clinical immunology

    2011  Volume 129, Issue 1, Page(s) 3–11; quiz 12–3

    Abstract: Mounting evidence suggests that air pollution contributes to the large global burden of respiratory and allergic diseases, including asthma, chronic obstructive pulmonary disease, pneumonia, and possibly tuberculosis. Although associations between air ... ...

    Abstract Mounting evidence suggests that air pollution contributes to the large global burden of respiratory and allergic diseases, including asthma, chronic obstructive pulmonary disease, pneumonia, and possibly tuberculosis. Although associations between air pollution and respiratory disease are complex, recent epidemiologic studies have led to an increased recognition of the emerging importance of traffic-related air pollution in both developed and less-developed countries, as well as the continued importance of emissions from domestic fires burning biomass fuels, primarily in the less-developed world. Emissions from these sources lead to personal exposures to complex mixtures of air pollutants that change rapidly in space and time because of varying emission rates, distances from source, ventilation rates, and other factors. Although the high degree of variability in personal exposure to pollutants from these sources remains a challenge, newer methods for measuring and modeling these exposures are beginning to unravel complex associations with asthma and other respiratory tract diseases. These studies indicate that air pollution from these sources is a major preventable cause of increased incidence and exacerbation of respiratory disease. Physicians can help to reduce the risk of adverse respiratory effects of exposure to biomass and traffic air pollutants by promoting awareness and supporting individual and community-level interventions.
    MeSH term(s) Air Pollutants/adverse effects ; Air Pollution/adverse effects ; Biofuels/adverse effects ; Environmental Monitoring ; Epidemiological Monitoring ; Humans ; Respiratory Tract Diseases/epidemiology ; Respiratory Tract Diseases/etiology ; Smoke/adverse effects ; Vehicle Emissions
    Chemical Substances Air Pollutants ; Biofuels ; Smoke ; Vehicle Emissions
    Language English
    Publishing date 2011-12-23
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S. ; Review
    ZDB-ID 121011-7
    ISSN 1097-6825 ; 1085-8725 ; 0091-6749
    ISSN (online) 1097-6825 ; 1085-8725
    ISSN 0091-6749
    DOI 10.1016/j.jaci.2011.11.021
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