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Article ; Online: Dose and blending fraction quantification for adaptive statistical iterative reconstruction based on low-contrast detectability in abdomen CT.

Zhou, Yifang

Journal of applied clinical medical physics

2020 Volume 21, Issue 2, Page(s) 128–135

Abstract: Purpose: The utilization of iterative reconstruction makes it difficult to identify the dose-noise relationship, resulting in empirical design of scan protocols and inconsistent conclusions on dose reduction for consistent image quality. This study was ... ...

Abstract	Purpose: The utilization of iterative reconstruction makes it difficult to identify the dose-noise relationship, resulting in empirical design of scan protocols and inconsistent conclusions on dose reduction for consistent image quality. This study was to quantitatively determine the dose and the blending fraction of adaptive statistical iterative reconstruction (ASIR) based on the specified low-contrast detectability (LCD). Methods: A tissue equivalent abdomen phantom and a GE discovery 750 HD computed tomography (CT) were utilized. The normality of the noise distribution was tested at various spatial scales (2.1-9.8 mm) in the presence of ASIR (10-100%) with a wide range of doses (2.24-38 mGy). The statically defined minimum detectable contrast (MDC) was used as the image quality metric. The parametric model decomposed the MDC into two terms: one with and the other without ASIR, each was related to the dose in the form of power law with factors and indices dependent on spatial scales. The parameters were identified by least-square fitting to the experimental data. By considering the constraint of the blending fraction in the range of [0, 1], the dose and ASIR blending fraction were determined for any specified low-contrast detectability (LCD), quantified by the MDC at the concerned lesion size. Results: It was verified that noise distribution is normal in the presence of ASIR. It was also found that the noises obtained from the subtractions of adjacent slices had an underestimate of 20% as compared to the ground truth noises, regardless of the spatial scale, pitch, or ASIR blending fraction. The least-square fitting for the parametric model resulted in correlation coefficients from 0.905 to 0.996. The root-mean-square errors ranged from 1.27% to 7.15%. Conclusion: The parametric model can be used to form a look-up-table for dose and ASIR blending fraction. The dose choices may be substantially limited in some cases depending on the required LCD.
MeSH term(s)	Algorithms ; Contrast Media ; Humans ; Image Processing, Computer-Assisted/methods ; Least-Squares Analysis ; Phantoms, Imaging ; Radiation Dosage ; Radiographic Image Interpretation, Computer-Assisted/methods ; Radiography, Abdominal ; Reproducibility of Results ; Signal-To-Noise Ratio ; Tomography, X-Ray Computed
Chemical Substances	Contrast Media
Language	English
Publishing date	2020-01-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	2010347-5
ISSN	1526-9914 ; 1526-9914
ISSN (online)	1526-9914
ISSN	1526-9914
DOI	10.1002/acm2.12813
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Article ; Online: A Holistic Approach to CT Protocol and Dose Management.

Eastman, Emi / Pressman, Barry D / Roy, Lynne / Zhou, Yifang

Journal of the American College of Radiology : JACR

2024

Abstract: Purpose: Challenges from administrative support, scanners' heterogeneity, patient size variation, and protocol mapping hinder CT protocol and dose management. We present a holistic approach to overcome these challenges.: Methods: A dose tracking ... ...

Abstract	Purpose: Challenges from administrative support, scanners' heterogeneity, patient size variation, and protocol mapping hinder CT protocol and dose management. We present a holistic approach to overcome these challenges. Methods: A dose tracking software was selected with two key requirements: intelligent protocol mapping and customizable dose threshold settings according to the patient size. A multifaceted workflow was carefully implemented. It included patient size-dependent dose thresholds for e-mail alerts, a base protocol archive on a website with a unified format using an in-house developed reformat software upon protocol export, prompt dose alert follow-up, and well-controlled protocol changes. The thresholds were iteratively updated following protocol changes or review of dose statistics. The program outcome was evaluated using 11 protocols from January 2020 to May 2023 (N = 148,678) in comparison to ACR's achievable dose (AD) and dose reference levels (DRLs). Results: The 75th percentile dose data were lower than the ACR's DRL on average, ranging from -4.9% to -36%. The median doses were in a range of -23% to 19% on average in comparison with the ACR's AD. The median value from pulmonary embolism scans initially showed 36% higher than the AD but was gradually reduced to nearly 3% lower than the AD. The percentage of unjustified alerted cases decreased from 80% in first half year of 2020 to 17% in the first 5 months of 2023. Conclusions: The results showed that our holistic approach to protocol and dose management has been effective. The impact to practice has been prompt and sustainable.
Language	English
Publishing date	2024-01-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	2274861-1
ISSN	1558-349X ; 1546-1440
ISSN (online)	1558-349X
ISSN	1546-1440
DOI	10.1016/j.jacr.2024.01.008
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Article ; Online: Optimal dose determination for coronary artery calcium scoring CT at standard tube voltage.

Zhou, Yifang / Eastman, Emi / Lee, Christina / Scott, Alexander

European journal of radiology

2023 Volume 167, Page(s) 111029

Abstract: Objectives: Coronary artery calcium scoring (CACs) at 120 kVp is the standard practice. It is an important tool for preventative management of asymptomatic patients. However, the current dose delivery, albeit patient-size dependent, does not connect the ...

Abstract	Objectives: Coronary artery calcium scoring (CACs) at 120 kVp is the standard practice. It is an important tool for preventative management of asymptomatic patients. However, the current dose delivery, albeit patient-size dependent, does not connect the CACs specific noise requirement to the dose, causing significant dose variations. We propose a new approach for optimal dose determination by incorporating the patient-size dependent noise threshold. Methods: A polyethylene-based Mercury phantom of various diameters was scanned with a dual-source CT using CACs gating at different volume CT dose index (CTDI Results: A power-exponential relationship was found for the noise versus CTDI Conclusion: A new optimal dose scheme dictated by the target noise was established for CACs at 120 kVp. The proposed dose modulation can serve as the baseline from which further dose reduction is possible.
MeSH term(s)	Humans ; Calcium ; Retrospective Studies ; Coronary Vessels/diagnostic imaging ; Radiation Dosage ; Cone-Beam Computed Tomography ; Phantoms, Imaging
Chemical Substances	Calcium (SY7Q814VUP)
Language	English
Publishing date	2023-08-09
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	138815-0
ISSN	1872-7727 ; 0720-048X
ISSN (online)	1872-7727
ISSN	0720-048X
DOI	10.1016/j.ejrad.2023.111029
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Article ; Online: The efficacy of mindfulness-based interventions on mental health among university students

Xinyi Zuo / Yong Tang / Yifang Chen / Zhimiao Zhou

Frontiers in Public Health, Vol

a systematic review and meta-analysis

2023 Volume 11

Abstract: IntroductionWe aimed to estimate the effect of mindfulness therapy on mental health.MethodsTwo researchers searched 12 databases to identify relevant trials that were published from 1 January 2018 to 1 May 2023. We performed a meta-analysis to determine ... ...

Abstract	IntroductionWe aimed to estimate the effect of mindfulness therapy on mental health.MethodsTwo researchers searched 12 databases to identify relevant trials that were published from 1 January 2018 to 1 May 2023. We performed a meta-analysis to determine the effect of mindfulness therapy on depression, which was measured by the Beck Depression Inventory (BDI), Patient Health Questionnaire-9 (PHQ-9), Quick Inventory of Depressive Symptomatology (QIDS), Hamilton Depression Rating Scale (HDRS), Patient-Reported Outcomes Measurement Information System (PROMIS), Hospital Anxiety and Depression Scale (HADS), and Depression Anxiety Stress Scales (DASS); anxiety, which was measured by the Beck Anxiety Inventory (BAI), PROMIS, and DASS, Generalized Anxiety Disorder-7 (GAD-7); stress, which was measured by the Perceived Stress Scale (PSS), DASS, and GAD-7; mindfulness, which was measured by the GAD-7, Five Facet Mindfulness Questionnaire (FFMQ), Mindful Attention Awareness Scale (MAAS), Short Form-12 Mental Component Score (SF-12 MCS) and Short Form-12 Physical Component Score (SF-12 PCS); and sleep quality, which was measured by the Pittsburgh Sleep Quality Index (PSQI). After screening studies based on the inclusion and exclusion criteria, 11 randomized controlled trials (RCTs) involving 1,824 participants were ultimately included.ResultsAll these studies demonstrated positive effects of mindfulness therapy on depression (SMD = −0.33, 95% CI: [−0.44, −0.22], p < 0.00001, I2 = 29%), anxiety (SMD = −0.35, 95% CI: [−0.46, −0.25], p < 0.00001, I2 = 40%), stress (SMD = −0.39, 95% CI: [−0.48, −0.29], p < 0.00001, I2 = 69%) and sleep quality scores (SMD = −0.81, 95% CI: [−1.54, −0.09], p = 0.03, I2 = 0%). However, there was no significant difference in mindfulness (SMD = −0.12, 95% CI: [−0.36, −0.12], p = 0.34, I2 = 34%) between the mindfulness therapy group and the control group.DiscussionIn future studies, it is necessary to consider the investigation on whether the strategies of improving the mindfulness therapy in ...
Keywords	mindfulness ; university students ; anxiety ; depression ; stress ; sleep quality ; Public aspects of medicine ; RA1-1270
Subject code	150
Language	English
Publishing date	2023-11-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
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Article ; Online: Impact of Virtual Operating Room Tours on Relieving Perioperative Anxiety in Adult Patients: A Systematic Review.

Yu, Yaqian / Zhou, Xuchuan / Zeng, Guowei / Hou, Yifang

Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses

2023 Volume 38, Issue 4, Page(s) 657–663.e7

Abstract: Purpose: To evaluate the effects of virtual operating room tours on perioperative anxiety in adult patients.: Design: This study was a systematic review of randomized controlled trials (RCTs).: Methods: PubMed, Cochrane Library, Embase, Web of ... ...

Abstract	Purpose: To evaluate the effects of virtual operating room tours on perioperative anxiety in adult patients. Design: This study was a systematic review of randomized controlled trials (RCTs). Methods: PubMed, Cochrane Library, Embase, Web of Science, Proquest, Scopus, SinoMed, CNKI, and WanFang were systematically searched for English and Chinese RCTs published up to November 18, 2021, for studies on the effectiveness of virtual operating room tours in reducing perioperative anxiety in adult patients (>18 years of age). Primary and secondary outcomes were perioperative anxiety levels and understanding level of perioperative information and patient satisfaction, respectively. The data were synthesized using a qualitative method. Findings: Five studies were found eligible for inclusion; 3 studies showed a significant decrease in perioperative anxiety levels in patients of the virtual operating room tours group. Furthermore, the overall satisfaction, understanding of perioperative information, and preoperative preparedness were significantly enhanced respectively in 3 studies. Conclusions: This study showed the effectiveness of virtual operating room tour on alleviating perioperative anxiety on adult patients. Furthermore, the satisfaction and understanding of perioperative information in intervention group improved owing to these tours. Future quantitative studies are needed to support these findings.
MeSH term(s)	Humans ; Adult ; Operating Rooms ; Anxiety/prevention & control ; Anxiety Disorders ; Personal Satisfaction
Language	English
Publishing date	2023-01-23
Publishing country	United States
Document type	Systematic Review ; Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	1329844-6
ISSN	1532-8473 ; 0883-9433 ; 1089-9472
ISSN (online)	1532-8473
ISSN	0883-9433 ; 1089-9472
DOI	10.1016/j.jopan.2022.11.013
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Article ; Online: The impact of targeted nursing intervention on postoperative medication adherence, quality of life, and psychological flexibility of thyroid cancer patients.

Xu, Xiaohong / Zhou, Li / Qiu, Wen / Su, Yifang

Asia-Pacific journal of clinical oncology

2023

Abstract: Objective: To explore the effect of targeted nursing intervention on postoperative medication adherence, quality of life, and psychological flexibility of patients with thyroid cancer (TC).: Methods: A total of 330 patients were randomly divided into ...

Abstract	Objective: To explore the effect of targeted nursing intervention on postoperative medication adherence, quality of life, and psychological flexibility of patients with thyroid cancer (TC). Methods: A total of 330 patients were randomly divided into a Control group and an Intervention group (cases in the Intervention group were given targeted nursing interventions and cases in the Control group were given routine health education), with 165 cases in each group. In the Intervention group, targeted dietary and psychological nursing interventions were conducted on TC patients, and the effects of targeted nursing interventions on the quality of life, medication adherence, and psychological flexibility were compared through the SF-36 Short Form Health Survey, Morisky Medication Adherence Scale and Psychological Resilience Scale with the Control group. Univariate analysis and multiple stepwise regression analysis were performed to analyze the influencing factors of psychological flexibility in patients after nursing intervention. Results: The Intervention group patients, after nursing intervention, in terms of life quality, scores of social function, physical function, and mental function were all higher than those of the Control group. Note that, 160 patients in the Intervention group (96.97%) had better treatment scores, which was significantly higher than that in the Control group (84.24%). The scores of mental resilience in the Intervention group reached 67.82 ± 13.85, and the two items of resilience, control, and optimism were significantly improved compared with the Control group (p < 0.05). Factors that had greater impacts on the psychological flexibility of TC patients were: age, education, per capita monthly income, and family residence. Conclusion: Targeted nursing intervention had positive promoting effects on postoperative medication adherence, quality of life, and psychological flexibility of TC patients.
Language	English
Publishing date	2023-12-07
Publishing country	Australia
Document type	Journal Article
ZDB-ID	2187409-8
ISSN	1743-7563 ; 1743-7555
ISSN (online)	1743-7563
ISSN	1743-7555
DOI	10.1111/ajco.14037
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Article ; Online: The efficacy of mindfulness-based interventions on mental health among university students: a systematic review and meta-analysis.

Zuo, Xinyi / Tang, Yong / Chen, Yifang / Zhou, Zhimiao

Frontiers in public health

2023 Volume 11, Page(s) 1259250

Abstract: Introduction: We aimed to estimate the effect of mindfulness therapy on mental health.: Methods: Two researchers searched 12 databases to identify relevant trials that were published from 1 January 2018 to 1 May 2023. We performed a meta-analysis to ... ...

Abstract	Introduction: We aimed to estimate the effect of mindfulness therapy on mental health. Methods: Two researchers searched 12 databases to identify relevant trials that were published from 1 January 2018 to 1 May 2023. We performed a meta-analysis to determine the effect of mindfulness therapy on depression, which was measured by the Beck Depression Inventory (BDI), Patient Health Questionnaire-9 (PHQ-9), Quick Inventory of Depressive Symptomatology (QIDS), Hamilton Depression Rating Scale (HDRS), Patient-Reported Outcomes Measurement Information System (PROMIS), Hospital Anxiety and Depression Scale (HADS), and Depression Anxiety Stress Scales (DASS); anxiety, which was measured by the Beck Anxiety Inventory (BAI), PROMIS, and DASS, Generalized Anxiety Disorder-7 (GAD-7); stress, which was measured by the Perceived Stress Scale (PSS), DASS, and GAD-7; mindfulness, which was measured by the GAD-7, Five Facet Mindfulness Questionnaire (FFMQ), Mindful Attention Awareness Scale (MAAS), Short Form-12 Mental Component Score (SF-12 MCS) and Short Form-12 Physical Component Score (SF-12 PCS); and sleep quality, which was measured by the Pittsburgh Sleep Quality Index (PSQI). After screening studies based on the inclusion and exclusion criteria, 11 randomized controlled trials (RCTs) involving 1,824 participants were ultimately included. Results: All these studies demonstrated positive effects of mindfulness therapy on depression (SMD = -0.33, 95% CI: [-0.44, -0.22], Discussion: In future studies, it is necessary to consider the investigation on whether the strategies of improving the mindfulness therapy in adherence and fidelity can work on the improvement of the outcomes in mental health. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/, https://www.crd.york.ac.uk/PROSPERO/, identifier [CRD42023469301].
MeSH term(s)	Humans ; Mindfulness ; Mental Health ; Universities ; Depression/therapy ; Students ; Randomized Controlled Trials as Topic
Language	English
Publishing date	2023-11-30
Publishing country	Switzerland
Document type	Meta-Analysis ; Systematic Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2023.1259250
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Article ; Online: Guided isolation of enantiomeric lignans from Cimicifuga heracleifolia Kom. by antioxidant activity and molecular networking.

Sun, Yanwen / Chen, Liyi / Zhou, Yan / Han, Fei / Rong, Yifang / Ding, Liqin / Qiu, Feng

Phytochemistry

2024 Volume 221, Page(s) 114050

Abstract: Under the guidance of antioxidant evaluation combined with molecular networking, six pairs of enantiomeric lignans including seven undescribed ones (1a, 2a/2b-4a/4b), along with five known analogs (1b, 5a/5b-6a/6b) were isolated from Cimicifuga ... ...

Abstract	Under the guidance of antioxidant evaluation combined with molecular networking, six pairs of enantiomeric lignans including seven undescribed ones (1a, 2a/2b-4a/4b), along with five known analogs (1b, 5a/5b-6a/6b) were isolated from Cimicifuga heracleifolia Kom. Their structures were determined by extensive spectroscopic data analysis, including HRESIMS, 1D and 2D NMR, experimental and calculated ECD. All the enantiomeric isolates were evaluated for antioxidation by 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and 2, 2'-azino-bis (3-ethyl-benzothiazoline-6-sulfonic acid) (ABTS) free radical scavenging tests. Compounds 1a and 3a/3b exhibited great DPPH and ABTS scavenging activities. The results are of great value for understanding structurally interesting enantiomeric lignans with antioxidant activity from C. heracleifolia in depth and providing its further development in functional evaluation and drug development.
MeSH term(s)	Lignans/chemistry ; Antioxidants/chemistry ; Cimicifuga ; Molecular Structure ; Sulfonic Acids ; Benzothiazoles
Chemical Substances	Lignans ; Antioxidants ; 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid (28752-68-3) ; Sulfonic Acids ; Benzothiazoles
Language	English
Publishing date	2024-03-11
Publishing country	England
Document type	Journal Article
ZDB-ID	208884-8
ISSN	1873-3700 ; 0031-9422
ISSN (online)	1873-3700
ISSN	0031-9422
DOI	10.1016/j.phytochem.2024.114050
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Article ; Online: Ultra-stable dendrite-free Na and Li metal anodes enabled by tin selenide host material.

Wang, Yikun / Li, Ting / Chen, Bofeng / Jin, Haiyang / Qiao, Shuangyan / Zhou, Qianwen / Ma, Meng / Wu, Yifang / Chong, Shaokun

Journal of colloid and interface science

2024 Volume 660, Page(s) 885–895

Abstract: Lithium/sodium metal anodes are considered promising candidates to realize high-energy-density batteries because of their high theoretical specific capacity and low potential. However, their cycling stability are hindered by uncontrolled dendrites growth. ...

Abstract	Lithium/sodium metal anodes are considered promising candidates to realize high-energy-density batteries because of their high theoretical specific capacity and low potential. However, their cycling stability are hindered by uncontrolled dendrites growth. Herein, SnSe nanoparticles are tightly anchored on the fiber of carbon cloth (CC) to construct SnSe@CC host material in order to control Li/Na nucleation behavior and restrain dendrites growth. It is demonstrated that the alloying product of Li
Language	English
Publishing date	2024-01-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	241597-5
ISSN	1095-7103 ; 0021-9797
ISSN (online)	1095-7103
ISSN	0021-9797
DOI	10.1016/j.jcis.2024.01.128
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Article ; Online: Inhibition of TRPP3 by calmodulin through Ca

Liu, Xiong / Wang, Yifang / Weng, Ziyi / Xu, Qinyi / Zhou, Cefan / Tang, JingFeng / Chen, Xing-Zhen

Cell insight

2023 Volume 2, Issue 2, Page(s) 100088

Abstract: Transient receptor potential (TRP) polycystin-3 (TRPP3) is a non-selective cation channel activated by ... ...

Abstract	Transient receptor potential (TRP) polycystin-3 (TRPP3) is a non-selective cation channel activated by Ca
Language	English
Publishing date	2023-02-09
Publishing country	Netherlands
Document type	Journal Article
ISSN	2772-8927
ISSN (online)	2772-8927
DOI	10.1016/j.cellin.2023.100088
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