Article: Influence of acetate- vs. lactate-containing fluid bolus therapy on acid-base status, electrolytes, and plasma lactate in dogs.
Frontiers in veterinary science
2022 Volume 9, Page(s) 903091
Abstract: Objective: Acetate- and lactate-containing fluids influence the acid-base and electrolyte status. This prospective, randomized, clinical study compared two balanced crystalloid solutions regarding their influence on acid-base status, electrolytes, and ... ...
Abstract | Objective: Acetate- and lactate-containing fluids influence the acid-base and electrolyte status. This prospective, randomized, clinical study compared two balanced crystalloid solutions regarding their influence on acid-base status, electrolytes, and lactate values, when given to dogs as a resuscitation bolus of 30 mL/kg. Material and methods: One hundred client-owned dogs presenting to the emergency service with signs of fluid deficits were randomly assigned to receive an intravenous bolus of 30 mL/kg of either a lactate- (LAC), or an acetate-containing solution (ACET). Before and after the bolus, vital parameters were assessed, and a venous blood gas analysis was performed. Results: Both solutions performed equally well in decreasing the heart rate (ACET: -10 ± 27 bpm, LAC: -12 ± 30 bpm; Conclusion: Both solutions caused mild changes in electrolyte concentrations and had minor influence on acid-base status when used for bolus therapy in dogs with fluid deficits. Further studies are needed to evaluate their influence on acid-base status, lactate, and electrolytes when used in larger volumes and for a longer time span. |
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Language | English |
Publishing date | 2022-07-29 |
Publishing country | Switzerland |
Document type | Journal Article |
ZDB-ID | 2834243-4 |
ISSN | 2297-1769 |
ISSN | 2297-1769 |
DOI | 10.3389/fvets.2022.903091 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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