LIVIVO - Search results -

Search results

Result 1 - 10 of total 20

Search options

Article ; Online: Changes in Inflammatory Markers in Patients Treated for Buruli Ulcer and Their Ability to Predict Paradoxical Reactions.

Phelippeau, Michael / Marion, Estelle / Robbe-Saule, Marie / Ganlanon, Line / Chauty, Annick / Adeye, Ambroise / Blanchard, Simon / Johnson, Christian / Marsollier, Laurent / Dubee, Vincent

The Journal of infectious diseases

2023 Volume 228, Issue 11, Page(s) 1630–1639

Abstract: Mycobacterium ulcerans causes Buruli ulcer, the third most frequent mycobacterial disease after tuberculosis and leprosy. Transient clinical deteriorations, known as paradoxical reactions (PRs), occur in some patients during or after antibiotic treatment. ...

Abstract	Mycobacterium ulcerans causes Buruli ulcer, the third most frequent mycobacterial disease after tuberculosis and leprosy. Transient clinical deteriorations, known as paradoxical reactions (PRs), occur in some patients during or after antibiotic treatment. We investigated the clinical and biological features of PRs in a prospective cohort of 41 patients with Buruli ulcer from Benin. Neutrophil counts decreased from baseline to day 90, and interleukin 6 (IL-6), granulocyte colony-stimulating factor, and vascular endothelial growth factor were the cytokines displaying a significant monthly decrease relative to baseline. PRs occurred in 10 (24%) patients. The baseline biological and clinical characteristics of the patients presenting with PRs did not differ significantly from those of the other patients. However, the patients with PRs had significantly higher IL-6 and tumor necrosis factor alpha (TNF-α) concentrations on days 30, 60, and 90 after the start of antibiotic treatment. The absence of a decrease in IL-6 and TNF-α levels during treatment should alert clinicians to the possibility of PR onset.
MeSH term(s)	Humans ; Buruli Ulcer/drug therapy ; Prospective Studies ; Tumor Necrosis Factor-alpha ; Interleukin-6 ; Vascular Endothelial Growth Factor A ; Anti-Bacterial Agents/therapeutic use
Chemical Substances	Tumor Necrosis Factor-alpha ; Interleukin-6 ; Vascular Endothelial Growth Factor A ; Anti-Bacterial Agents
Language	English
Publishing date	2023-05-08
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3019-3
ISSN	1537-6613 ; 0022-1899
ISSN (online)	1537-6613
ISSN	0022-1899
DOI	10.1093/infdis/jiad176
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uh II Zs.50: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 445: Show issues

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Inverse correlation between salt tolerance and host-adaptation in mycobacteria.

Asmar, Shady / Sassi, Mohamed / Phelippeau, Michael / Drancourt, Michel

BMC research notes

2016 Volume 9, Page(s) 249

Abstract: Background: The genus Mycobacterium includes host-adapted organisms regarded as obligate and opportunistic pathogens and environmental organisms. Factors contributing to this wide range of adaptations are poorly known.: Results: We studied the salt ... ...

Abstract	Background: The genus Mycobacterium includes host-adapted organisms regarded as obligate and opportunistic pathogens and environmental organisms. Factors contributing to this wide range of adaptations are poorly known. Results: We studied the salt tolerance of 46 Mycobacterium species of medical interest. Representative strains of the Mycobacterium tuberculosis complex, Mycobacterium avium complex, Mycobacterium chelonae-abscessus complex, Mycobacterium ulcerans, Mycobacterium marinum, Mycobacterium lentiflavum, Mycobacterium fortuitum and Mycobacterium conceptionense were inoculated on Middlebrook 7H10 medium supplemented with 0-10% sodium chloride. Colonies were counted after 2-4 week incubation at the appropriate 30-37 °C temperature depending on the tested strain. Further comparative genomics was done on 15 Mycobacterium strains representing the spectrum of salt-tolerance of mycobacteria. Based on the results the different species were grouped according to their salt tolerance into a "salt-sensitive" group (growth up to ≤3% salt) containing the M. tuberculosis complex, Mycobacterium chelonae, Mycobacterium lentiflavum, Mycobacterium ulcerans and Mycobacterium marinum; a "salt-intermediate" group (growth between 4 and 6% salt) comprising Mycobacterium avium, Mycobacterium intracellulare, Mycobacterium chimaera and a "salt-resistant" group (growth up to >6%) comprising Mycobacterium homonissuis, Mycobacterium bolettii, Mycobacterium fortuitum and Mycobacterium conceptionense. Genomic analysis revealed that 290 genes were unique to species belonging to the salt-sensitive group; and that 15% were annotated as being functionally associated with the ESX secretion systems Pro-Glu and Pro-Pro-Glu family proteins. Conclusions: In this work we found an inverse correlation between salt tolerance and host adaptation. We thus propose that salinity is one of the multiple factors determining the ecological niches of mycobacteria.
MeSH term(s)	Adaptation, Physiological/genetics ; Adaptation, Physiological/physiology ; Bacterial Proteins/classification ; Bacterial Proteins/genetics ; Bacteriological Techniques/methods ; Cluster Analysis ; Environmental Microbiology ; Genes, Bacterial/genetics ; Genome, Bacterial/genetics ; Host-Pathogen Interactions ; Humans ; Mycobacterium/classification ; Mycobacterium/genetics ; Mycobacterium/physiology ; Mycobacterium Infections/microbiology ; Salt-Tolerance/genetics ; Salt-Tolerance/physiology ; Sequence Analysis, DNA ; Species Specificity
Chemical Substances	Bacterial Proteins
Language	English
Publishing date	2016-04-29
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2413336-X
ISSN	1756-0500 ; 1756-0500
ISSN (online)	1756-0500
ISSN	1756-0500
DOI	10.1186/s13104-016-2054-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Full text

Order via subito

Details ▾
- Full text online
- Order with fees

Article ; Online: "Mycobacterium mephinesia", a Mycobacterium terrae complex species of clinical interest isolated in French Polynesia.

Saad, Jamal / Phelippeau, Michael / Khoder, May / Lévy, Marc / Musso, Didier / Drancourt, Michel

Scientific reports

2019 Volume 9, Issue 1, Page(s) 11169

Abstract: A 59-year-old tobacco smoker male with chronic bronchitis living in Taravao, French Polynesia, Pacific, presented with a two-year growing nodule in the middle lobe of the right lung. A guided bronchoalveolar lavage inoculated onto Löwenstein-Jensen ... ...

Abstract	A 59-year-old tobacco smoker male with chronic bronchitis living in Taravao, French Polynesia, Pacific, presented with a two-year growing nodule in the middle lobe of the right lung. A guided bronchoalveolar lavage inoculated onto Löwenstein-Jensen medium yielded colonies of a rapidly-growing non-chromogenic mycobacterium designed as isolate P7213. The isolate could not be identified using routine matrix-assisted laser desorption ionization-time of flight-mass spectrometry and phenotypic and probe-hybridization techniques and yielded 100% and 97% sequence similarity with the respective 16S rRNA and rpoB gene sequences of Mycobacterium virginiense in the Mycobacterium terrae complex. Electron microscopy showed a 1.15 µm long and 0.38 µm large bacillus which was in vitro susceptible to rifampicin, rifabutin, ethambutol, isoniazid, doxycycline and kanamycin. Its 4,511,948-bp draft genome exhibited a 67.6% G + C content with 4,153 coding-protein genes and 87 predicted RNA genes. Genome sequence-derived DNA-DNA hybridization, OrthoANI and pangenome analysis confirmed isolate P7213 was representative of a new species in the M. terrae complex. We named this species "Mycobacterium mephinesia".
MeSH term(s)	Bronchoalveolar Lavage ; Genome, Bacterial ; Humans ; Lung/microbiology ; Male ; Middle Aged ; Mycobacterium/genetics ; Mycobacterium/isolation & purification ; Nontuberculous Mycobacteria/isolation & purification ; Polynesia ; RNA, Ribosomal, 16S ; Sequence Analysis, DNA
Chemical Substances	RNA, Ribosomal, 16S
Language	English
Publishing date	2019-08-01
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-019-47674-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Diversity of Mycobacterium tuberculosis lineages in French Polynesia.

Osman, Djaltou Aboubaker / Phelippeau, Michael / Drancourt, Michel / Musso, Didier

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi

2017 Volume 50, Issue 2, Page(s) 199–206

Abstract: Background/purpose: French Polynesia is an overseas territory located in the South Pacific. The incidence of tuberculosis in French Polynesia has been stable since 2000 with an average of 20 cases/y/100,000 inhabitants. Molecular epidemiology of ... ...

Abstract	Background/purpose: French Polynesia is an overseas territory located in the South Pacific. The incidence of tuberculosis in French Polynesia has been stable since 2000 with an average of 20 cases/y/100,000 inhabitants. Molecular epidemiology of Mycobacterium tuberculosis in French Polynesia is unknown because M. tuberculosis isolates have not been routinely genotyped. Methods: From 2009 to 2012, 34 isolates collected from 32 French Polynesian patients were identified as M. tuberculosis by probe hybridization. These isolates were genotyped using spoligotyping and 24-loci mycobacterial interspersed repetitive units (MIRUs)-variable number of tandem repeat (VNTR). Spoligotype patterns obtained using commercial kits were compared with the online international database SITVIT. MIRU-VNTR genotyping was performed using an in-house protocol based on capillary electrophoresis sizing for 24-loci MIRU-VNTR genotyping. Results: The results of the spoligotyping method revealed that 25 isolates grouped into six previously described spoligotypes [H1, H3, U likely (S), T1, Manu, and Beijing] and nine isolates grouped into six new spoligotypes. Comparison with the international database MIRU-VNTRplus distributed 30 isolates into five lineages (Haarlem, Latin American Mediterranean, S, X, and Beijing) and four as unassigned isolates. Conclusion: Genotyping identified four phylogenetic lineages belonging to the modern Euro-American subgroup, one Beijing genotype responsible for worldwide pandemics, including remote islands in the South Pacific, and one Manu genotype of the ancestral lineage of M. tuberculosis.
MeSH term(s)	Adult ; Aged ; Bacterial Typing Techniques/methods ; Biodiversity ; DNA, Bacterial/genetics ; Female ; Genes, Bacterial ; Genetic Variation ; Geographic Mapping ; Humans ; Male ; Middle Aged ; Molecular Epidemiology/methods ; Mycobacterium tuberculosis/classification ; Mycobacterium tuberculosis/genetics ; Mycobacterium tuberculosis/isolation & purification ; Polynesia/epidemiology ; Tuberculosis/epidemiology ; Tuberculosis/microbiology ; Young Adult
Chemical Substances	DNA, Bacterial
Language	English
Publishing date	2017-04
Publishing country	England
Document type	Journal Article
ZDB-ID	1497590-7
ISSN	1995-9133 ; 1684-1182 ; 0253-2662
ISSN (online)	1995-9133
ISSN	1684-1182 ; 0253-2662
DOI	10.1016/j.jmii.2015.05.018
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.B 2083: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Mycobacterium abscessus pneumonia in a South Pacific islander.

Phelippeau, Michael / Musso, Didier / Drancourt, Michel

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi

2015 Volume 50, Issue 3, Page(s) 393–394

MeSH term(s)	Aged ; Anti-Bacterial Agents/therapeutic use ; Combined Modality Therapy ; Humans ; Molecular Diagnostic Techniques ; Mycobacterium Infections, Nontuberculous/complications ; Mycobacterium Infections, Nontuberculous/diagnosis ; Mycobacterium Infections, Nontuberculous/microbiology ; Mycobacterium Infections, Nontuberculous/therapy ; Mycobacterium abscessus ; Polynesia ; Pulmonary Disease, Chronic Obstructive/complications ; Respiratory Therapy ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ; Sputum/microbiology ; Tomography, X-Ray Computed ; Treatment Outcome
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2015-01-30
Publishing country	England
Document type	Case Reports ; Letter
ZDB-ID	1497590-7
ISSN	1995-9133 ; 1684-1182 ; 0253-2662
ISSN (online)	1995-9133
ISSN	1684-1182 ; 0253-2662
DOI	10.1016/j.jmii.2015.01.008
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.B 2083: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Respiratory tract isolation of Mycobacterium europaeum following influenza infection in an immunocompromised patient: a case report.

Phelippeau, Michael / Delord, Marion / Drancourt, Michel / Brouqui, Philippe

Journal of medical case reports

2014 Volume 8, Page(s) 463

Abstract: Introduction: Mycobacterium europaeum, a slow-growing nontuberculous mycobacteria belonging to the Mycobacterium simiae complex, was described after the seminal characterization of five isolates collected from three sputum specimens and a jaw gland ... ...

Abstract	Introduction: Mycobacterium europaeum, a slow-growing nontuberculous mycobacteria belonging to the Mycobacterium simiae complex, was described after the seminal characterization of five isolates collected from three sputum specimens and a jaw gland biopsy in Italy, Greece and Sweden. Five respiratory tract isolates were further reported in Iran. Here, we report the first isolation of M. europaeum in France, in the respiratory tract of a patient co-infected with human immunodeficiency virus and hepatitis C virus. Case presentation: A 49-year-old Caucasian woman with a 26-year history of human immunodeficiency virus-hepatitis C virus co-infection was admitted for significant influenza-like syndrome in a context of repetitive exacerbations of chronic obstructive pulmonary disease. Significant biological parameters included lymphocytes of 1.6G/L including 237/mm3 T4 lymphocytes, a human immunodeficiency virus viral load of 1.6 log and a hepatitis C virus viral load of 6 log. Reverse-transcriptase polymerase chain reaction of her nasopharyngeal aspiration confirmed influenza A H1N1. Three sputum specimens lacked acid-fast bacilli but one grew mycobacteria identified by using matrix-assisted laser desorption ionization/time-of-flight mass spectrometry as M. europaeum with a 1.56 log score. A 1,482-bp 16S ribosomal ribonucleic acid gene sequence yielded 99% similarity with both Mycobacterium parascrofulaceum ATCC BAA-614 and M. europaeum DSM 45397T and partial rpoB polymerase chain reaction-sequencing yielded a 725-bp sequence exhibiting 100% similarity with M. europaeum strain DSM 45397T. Conclusions: We report the first isolation of M. europaeum in France, in the respiratory tract of a patient co-infected with human immunodeficiency virus and hepatitis C virus. M. europaeum warrants further attention in immunosuppressed patients with influenza, using matrix-assisted laser desorption ionization/time-of-flight mass spectrometry and rpoB partial sequencing as tools for its accurate identification.
MeSH term(s)	Coinfection ; Female ; France ; HIV Infections/complications ; HIV Infections/immunology ; Hepatitis C/complications ; Hepatitis C/immunology ; Humans ; Immunocompromised Host/immunology ; Influenza A Virus, H1N1 Subtype ; Influenza, Human/complications ; Influenza, Human/diagnosis ; Influenza, Human/immunology ; Mass Spectrometry ; Middle Aged ; Mycobacterium/isolation & purification ; Respiratory System/immunology ; Respiratory System/microbiology ; Reverse Transcriptase Polymerase Chain Reaction ; Sputum/microbiology
Language	English
Publishing date	2014-12-25
Publishing country	England
Document type	Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2269805-X
ISSN	1752-1947 ; 1752-1947
ISSN (online)	1752-1947
ISSN	1752-1947
DOI	10.1186/1752-1947-8-463
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Full text

Order via subito

Details ▾
- Full text online
- Order with fees

Article: Draft Genome Sequence of Mycobacterium lentiflavum CSUR P1491.

Phelippeau, Michael / Croce, Olivier / Robert, Catherine / Raoult, Didier / Drancourt, Michel

Genome announcements

2015 Volume 3, Issue 4

Abstract: We announce the draft genome sequence of Mycobacterium lentiflavum strain CSUR P1491, a nontuberculous mycobacterium responsible for opportunistic potentially life-threatening infections in immunocompromised patients. The genome described here comprises ... ...

Abstract	We announce the draft genome sequence of Mycobacterium lentiflavum strain CSUR P1491, a nontuberculous mycobacterium responsible for opportunistic potentially life-threatening infections in immunocompromised patients. The genome described here comprises a 6,818,507-bp chromosome exhibiting a 65.75% G+C content, 6,354 protein-coding genes, and 75 RNA genes.
Language	English
Publishing date	2015-07-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	2704277-7
ISSN	2169-8287
ISSN	2169-8287
DOI	10.1128/genomeA.00817-15
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Draft Genome Sequence of Mycobacterium europaeum Strain CSUR P1344.

Phelippeau, Michael / Croce, Olivier / Robert, Catherine / Raoult, Didier / Drancourt, Michel

Genome announcements

2015 Volume 3, Issue 4

Abstract: We report the draft genome sequence of Mycobacterium europaeum strain CSUR P1344, a slowly growing mycobacterium of the Mycobacterium simiae complex and opportunistic respiratory tract colonizer and pathogen. This genome of 6,152,523 bp exhibits a 68.18% ...

Abstract	We report the draft genome sequence of Mycobacterium europaeum strain CSUR P1344, a slowly growing mycobacterium of the Mycobacterium simiae complex and opportunistic respiratory tract colonizer and pathogen. This genome of 6,152,523 bp exhibits a 68.18% G+C content, encoding 5,814 predicted proteins and 74 RNAs.
Language	English
Publishing date	2015-07-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	2704277-7
ISSN	2169-8287
ISSN	2169-8287
DOI	10.1128/genomeA.00816-15
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Draft Genome Sequence of Mycobacterium bohemicum Strain DSM 44277T.

Asmar, Shady / Phelippeau, Michael / Robert, Catherine / Croce, Olivier / Drancourt, Michel

Genome announcements

2015 Volume 3, Issue 4

Abstract: The Mycobacterium bohemicum strain is a nontuberculosis species mainly responsible for pediatric cervical lymphadenitis. The draft genome of M. bohemicum DSM 44277(T) comprises 5,097,190 bp exhibiting a 68.64% G+C content, 4,840 protein-coding genes, and ...

Abstract	The Mycobacterium bohemicum strain is a nontuberculosis species mainly responsible for pediatric cervical lymphadenitis. The draft genome of M. bohemicum DSM 44277(T) comprises 5,097,190 bp exhibiting a 68.64% G+C content, 4,840 protein-coding genes, and 75 predicted RNA genes.
Language	English
Publishing date	2015-08-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	2704277-7
ISSN	2169-8287
ISSN	2169-8287
DOI	10.1128/genomeA.00878-15
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: “Mycobacterium mephinesia”, a Mycobacterium terrae complex species of clinical interest isolated in French Polynesia

Jamal Saad / Michael Phelippeau / May Khoder / Marc Lévy / Didier Musso / Michel Drancourt

Scientific Reports, Vol 9, Iss 1, Pp 1-

2019 Volume 11

Abstract: Abstract A 59-year-old tobacco smoker male with chronic bronchitis living in Taravao, French Polynesia, Pacific, presented with a two-year growing nodule in the middle lobe of the right lung. A guided bronchoalveolar lavage inoculated onto Löwenstein- ... ...

Abstract	Abstract A 59-year-old tobacco smoker male with chronic bronchitis living in Taravao, French Polynesia, Pacific, presented with a two-year growing nodule in the middle lobe of the right lung. A guided bronchoalveolar lavage inoculated onto Löwenstein-Jensen medium yielded colonies of a rapidly-growing non-chromogenic mycobacterium designed as isolate P7213. The isolate could not be identified using routine matrix-assisted laser desorption ionization-time of flight-mass spectrometry and phenotypic and probe-hybridization techniques and yielded 100% and 97% sequence similarity with the respective 16S rRNA and rpoB gene sequences of Mycobacterium virginiense in the Mycobacterium terrae complex. Electron microscopy showed a 1.15 µm long and 0.38 µm large bacillus which was in vitro susceptible to rifampicin, rifabutin, ethambutol, isoniazid, doxycycline and kanamycin. Its 4,511,948-bp draft genome exhibited a 67.6% G + C content with 4,153 coding-protein genes and 87 predicted RNA genes. Genome sequence-derived DNA-DNA hybridization, OrthoANI and pangenome analysis confirmed isolate P7213 was representative of a new species in the M. terrae complex. We named this species “Mycobacterium mephinesia”.
Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2019-08-01T00:00:00Z
Publisher	Nature Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED