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Article ; Online: Single-Incision Laparoscopic Percutaneous Extraperitoneal Surgery for the Treatment of Incarcerated Indirect Inguinal Hernia in Children.

He, Min / Xiong, Jieni / Cai, Jiabin / Yan, Xiang

Journal of laparoendoscopic & advanced surgical techniques. Part A

2023 Volume 34, Issue 1, Page(s) 88–91

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Child ; Humans ; Infant ; Hernia, Inguinal/surgery ; Hernia, Inguinal/etiology ; Retrospective Studies ; Treatment Outcome ; Herniorrhaphy/adverse effects ; Laparoscopy/adverse effects ; Surgical Wound ; Necrosis/surgery
Language	English
Publishing date	2023-08-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	1381909-4
ISSN	1557-9034 ; 1092-6429
ISSN (online)	1557-9034
ISSN	1092-6429
DOI	10.1089/lap.2023.0230
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Zs.A 3246: Show issues

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Article ; Online: Enrichment of nucleobase adducts from genomic DNA in the cytoplasm by solid-phase extraction.

Wu, Jiabin / Cai, Zongwei

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

2022 Volume 1215, Page(s) 123574

Abstract: The exact levels of some DNA adducts, like N7-deoxyguanosine (N7-dG), can be under-calculated since these adducts may depurinate due to their chemical instability, leading to corresponding nucleobase adducts being released into the cytoplasm. To ... ...

Abstract	The exact levels of some DNA adducts, like N7-deoxyguanosine (N7-dG), can be under-calculated since these adducts may depurinate due to their chemical instability, leading to corresponding nucleobase adducts being released into the cytoplasm. To accurately quantify the levels of DNA adducts, it is necessary to consider those modified nucleobases. However, high levels and diversity of cytoplasmic small molecule metabolites (SMMs) can strongly interfere with the detection of adducts, and it is almost impossible to remove them with nucleobase adducts being well retained. Therefore, we aimed to establish an optimized enrichment method based on solid-phase extraction (SPE) to reduce the co-elution of SMMs with target analytes. In this vein, we employed three bisphenols (BPA, BPF, and BPAF) as examples, prepared corresponding N7-guanine (N7-Gua) adducts, loaded on an Oasis hydrophilic-lipophilic balance ® (HLB) cartridge, used a series of mobile phases containing different percentage of methanol for elution, and evaluated the levels of these adducts in each eluent. First, we found that neutral samples led to the best retention for all three adducts compared with acidified or basified ones. We next employed normal distribution fitting model to characterize the elution of analytes from H
MeSH term(s)	DNA Adducts ; Methanol ; DNA/chemistry ; Guanine/chemistry ; Indicators and Reagents ; Cytoplasm/metabolism ; Solid Phase Extraction ; Genomics
Chemical Substances	DNA Adducts ; Methanol (Y4S76JWI15) ; DNA (9007-49-2) ; Guanine (5Z93L87A1R) ; Indicators and Reagents
Language	English
Publishing date	2022-12-18
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1180823-8
ISSN	1873-376X ; 0378-4347 ; 1570-0232 ; 1387-2273
ISSN (online)	1873-376X
ISSN	0378-4347 ; 1570-0232 ; 1387-2273
DOI	10.1016/j.jchromb.2022.123574
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Zs.A 813: Show issues

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Article ; Online: A new toxicity mechanism of N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone: Formation of DNA adducts in mammalian cells and aqueous organisms.

Wu, Jiabin / Cao, Guodong / Zhang, Feng / Cai, Zongwei

The Science of the total environment

2023 Volume 866, Page(s) 161373

Abstract: N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine-quinone (6PPDQ), one of the oxidation products of rubber antioxidant 6PPD, has been identified as a novel toxicant to many organisms. However, an understanding of its underlying toxicity mechanisms ... ...

Abstract	N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine-quinone (6PPDQ), one of the oxidation products of rubber antioxidant 6PPD, has been identified as a novel toxicant to many organisms. However, an understanding of its underlying toxicity mechanisms remained elusive. In this study, we reported that 6PPDQ could react with deoxyguanosine to form one isomer of 3-hydroxy-1, N
MeSH term(s)	Chromatography, High Pressure Liquid ; Deoxyguanosine/chemistry ; DNA Adducts/metabolism ; Quinones ; Spectrometry, Mass, Electrospray Ionization/methods ; Tandem Mass Spectrometry/methods ; Phenylenediamines/chemistry ; Phenylenediamines/metabolism ; Phenylenediamines/toxicity ; Benzoquinones/chemistry ; Benzoquinones/metabolism ; Benzoquinones/toxicity ; Antioxidants/chemistry ; Antioxidants/metabolism ; Antioxidants/toxicity ; Chlamydomonas reinhardtii/drug effects ; Chlamydomonas reinhardtii/genetics ; Chlamydomonas reinhardtii/metabolism ; Humans ; A549 Cells
Chemical Substances	Deoxyguanosine (G9481N71RO) ; DNA Adducts ; N-(1,3-dimethylbutyl)-N'-phenyl-1,4-phenylenediamine (HJD0U67PS1) ; Quinones ; N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone ; Phenylenediamines ; Benzoquinones ; Antioxidants
Language	English
Publishing date	2023-01-06
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2022.161373
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Zs.A 949: Show issues

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ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Mass spectrometric determination of N7-HPTE-dG and N7-HPTE-Gua in mammalian cells and mice exposed to methoxychlor, an emergent persistent organic pollutant.

Wu, Jiabin / Wang, Fuyue / Xie, Guangshan / Cai, Zongwei

Journal of hazardous materials

2022 Volume 432, Page(s) 128741

Abstract: Methoxychlor (MXC) is an organopesticide classified as a "Proposed Persistent Organic Pollutant" in the Stockholm Convention, and recent studies revealed that MXC could induce DNA strand breaks, whereas its underlying mechanisms were underinvestigated. ... ...

Abstract	Methoxychlor (MXC) is an organopesticide classified as a "Proposed Persistent Organic Pollutant" in the Stockholm Convention, and recent studies revealed that MXC could induce DNA strand breaks, whereas its underlying mechanisms were underinvestigated. Here, we first reported that hydroxymethoxychlor (HPTE), one of MXC's active metabolites, could be oxidized in vivo to form quinone intermediate, which attacked N7 position of 2'-deoxyguanosine to form N7-HPTE-deoxyguanosine (N7-HPTE-dG), followed by depurination to produce N7-HPTE-guanine (N7-HPTE-Gua) in MXC-treated mammalian cells and tissues from mice fed with MXC, employing an ultra-performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UPLC-ESI-MS/MS) method. We observed a positive correlation between the doses of MXC exposure and the levels of N7-HPTE-Gua and N7-HPTE-dG in cytoplasm and genomic DNA, respectively. Furthermore, after removal of exogenous MXC, the amount of genomic N7-HPTE-dG was significantly decreased during 24 h, while the level of cytoplasmic N7-HPTE-Gua was elevated during first 12 h, indicating the accumulation of the N7-HPTE-Gua in cells. Additionally, for animal experiment, genomic N7-HPTE-dG was observed in livers and cortexes from female C57BL/6 mice fed with MXC, suggesting a potential mechanism of its hepatoxicity and neurotoxicity. Overall, our study provides new understanding about the formation of MXC-induced DNA adducts in mammalian cells and animal models.
MeSH term(s)	Animals ; DNA Adducts ; Deoxyguanosine ; Female ; Mammals/metabolism ; Methoxychlor/toxicity ; Mice ; Mice, Inbred C57BL ; Persistent Organic Pollutants ; Phenols/toxicity ; Tandem Mass Spectrometry
Chemical Substances	DNA Adducts ; Phenols ; Deoxyguanosine (G9481N71RO) ; Methoxychlor (RIA79UD69L)
Language	English
Publishing date	2022-03-22
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1491302-1
ISSN	1873-3336 ; 0304-3894
ISSN (online)	1873-3336
ISSN	0304-3894
DOI	10.1016/j.jhazmat.2022.128741
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Study on the variable length simple pendulum oscillation based on the relative mode transfer method.

Yu, Yang / Ma, Jing / Shi, Xiangli / Wu, Jiabin / Cai, Shouyu / Li, Zilin / Wang, Wei / Wei, Hongtao / Wei, Ronghan

PloS one

2024 Volume 19, Issue 4, Page(s) e0299399

Abstract: In this study, we employed the principle of Relative Mode Transfer Method (RMTM) to establish a model for a single pendulum subjected to sudden changes in its length. An experimental platform for image processing was constructed to accurately track the ... ...

Abstract	In this study, we employed the principle of Relative Mode Transfer Method (RMTM) to establish a model for a single pendulum subjected to sudden changes in its length. An experimental platform for image processing was constructed to accurately track the position of a moving ball, enabling experimental verification of the pendulum's motion under specific operating conditions. The experimental data demonstrated excellent agreement with simulated numerical results, validating the effectiveness of the proposed methodology. Furthermore, we performed simulations of a double obstacle pendulum system, investigating the effects of different parameters, including obstacle pin positions, quantities, and initial release angles, on the pendulum's motion through numerical simulations. This research provides novel insights into addressing the challenges associated with abrupt and continuous changes in pendulum length.
MeSH term(s)	Image Processing, Computer-Assisted ; Motion ; Physical Therapy Modalities
Language	English
Publishing date	2024-04-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0299399
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Article ; Online: Recent Advances in Hierarchical Porous Engineering of MOFs and Their Derived Materials for Catalytic and Battery: Methods and Application.

Li, Qian / Li, Qun / Wang, Zhewei / Zheng, Xiaobo / Cai, Shichang / Wu, Jiabin

Small (Weinheim an der Bergstrasse, Germany)

2023 Volume 20, Issue 8, Page(s) e2303473

Abstract: Hierarchical porous materials have attracted the attention of researchers due to their enormous specific surface area, maximized active site utilization efficiency, and unique structure and properties. In this context, metal-organic frameworks (MOFs) ... ...

Abstract	Hierarchical porous materials have attracted the attention of researchers due to their enormous specific surface area, maximized active site utilization efficiency, and unique structure and properties. In this context, metal-organic frameworks (MOFs) offer a unique mix of properties that make them particularly appealing as tunable porous substrates containing highly active sites. This review focuses on recent advances in the types and synthetic strategies of hierarchical porous MOFs and their derived materials. Furthermore, it highlights the relationship between the mass diffusion and transport of hierarchical porous structures and the pore size with examples and simulations, while identifying their potential and limitations. On this basis, how the synthesis conditions affect the structure and electrochemical properties of MOFs based hierarchical porous materials with different structures is discussed, highlighting the prospects and challenges for the synthetization, as well as further scientific research and practical applications. Finally, some insights into current research and future design ideas for advanced MOFs based hierarchical porous materials are presented.
Language	English
Publishing date	2023-10-15
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	2168935-0
ISSN	1613-6829 ; 1613-6810
ISSN (online)	1613-6829
ISSN	1613-6810
DOI	10.1002/smll.202303473
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Article ; Online: An efficient self-attention network for skeleton-based action recognition.

Qin, Xiaofei / Cai, Rui / Yu, Jiabin / He, Changxiang / Zhang, Xuedian

Scientific reports

2022 Volume 12, Issue 1, Page(s) 4111

Abstract: There has been significant progress in skeleton-based action recognition. Human skeleton can be naturally structured into graph, so graph convolution networks have become the most popular method in this task. Most of these state-of-the-art methods ... ...

Abstract	There has been significant progress in skeleton-based action recognition. Human skeleton can be naturally structured into graph, so graph convolution networks have become the most popular method in this task. Most of these state-of-the-art methods optimized the structure of human skeleton graph to obtain better performance. Based on these advanced algorithms, a simple but strong network is proposed with three major contributions. Firstly, inspired by some adaptive graph convolution networks and non-local blocks, some kinds of self-attention modules are designed to exploit spatial and temporal dependencies and dynamically optimize the graph structure. Secondly, a light but efficient architecture of network is designed for skeleton-based action recognition. Moreover, a trick is proposed to enrich the skeleton data with bones connection information and make obvious improvement to the performance. The method achieves 90.5% accuracy on cross-subjects setting (NTU60), with 0.89M parameters and 0.32 GMACs of computation cost. This work is expected to inspire new ideas for the field.
MeSH term(s)	Algorithms ; Humans ; Neural Networks, Computer ; Recognition, Psychology ; Skeleton
Language	English
Publishing date	2022-03-08
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-022-08157-5
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Article ; Online: Social Determinants of Health, Cardiovascular Health, and Outcomes in Community-Dwelling Adults Without Cardiovascular Disease.

Cai, Anping / Chen, Chaolei / Wang, Jiabin / Ou, Yanqiu / Nie, Zhiqiang / Feng, Yingqing

JACC. Asia

2023 Volume 4, Issue 1, Page(s) 44–54

Abstract: Background: Limited data exist regarding the prognostic implications of social determinants of health (SDOH) and cardiovascular health (CVH) in Chinese community populations.: Objectives: The aim of this study was to evaluate the associations of SDOH ...

Abstract	Background: Limited data exist regarding the prognostic implications of social determinants of health (SDOH) and cardiovascular health (CVH) in Chinese community populations. Objectives: The aim of this study was to evaluate the associations of SDOH and CVH with major adverse cardiovascular events (MACE) and all-cause death. Methods: Individuals without cardiovascular disease were obtained from the China Patient-Centered Evaluative Assessment of Cardiac Events Million Persons Project. SDOH (educational attainment, economic stability, health care access, social support, and neighborhood) and CVH components were extracted. Participants were divided into groups with low and high burden of unfavorable SDOH and groups with poor, intermediate, and ideal CVH. MACE (a composite of coronary heart disease or myocardial infarction, stroke, heart failure, and cardiovascular death) and all-cause death were identified by linking hospital records with resident identity card number. Results: Among the cohort (n = 38,571, median age 54 years, 60.5% women), the proportion of individuals with a high burden of unfavorable SDOH was 68.9%, and that with poor CVH was 30.7%. In reference to the group with a low burden of unfavorable SDOH, the adjusted HRs for MACE and all-cause death in the high burden group were 1.18 (95% CI: 1.08-1.30) and 1.35 (95% CI: 1.09-1.68), respectively. In reference to the group with ideal CVH, poor CVH was associated with higher risks for MACE and all-cause death. A high burden of unfavorable SDOH and poor CVH exerted joint effects on all-cause death (HR: 2.20; 95% CI: 1.08-4.48). Conclusions: A high burden of unfavorable SDOH and poor CVH were associated with increased risks for MACE and mortality. Dedicated efforts are needed to address these health disparities.
Language	English
Publishing date	2023-10-31
Publishing country	United States
Document type	Journal Article
ISSN	2772-3747
ISSN (online)	2772-3747
DOI	10.1016/j.jacasi.2023.09.003
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Article ; Online: Parallel Hybrid Particle Swarm Algorithm for Workshop Scheduling Based on Spark

Tianhua Zheng / Jiabin Wang / Yuxiang Cai

Algorithms, Vol 14, Iss 262, p

2021 Volume 262

Abstract: In hybrid mixed-flow workshop scheduling, there are problems such as mass production, mass manufacturing, mass assembly and mass synthesis of products. In order to solve these problems, combined with the Spark platform, a hybrid particle swarm algorithm ... ...

Abstract	In hybrid mixed-flow workshop scheduling, there are problems such as mass production, mass manufacturing, mass assembly and mass synthesis of products. In order to solve these problems, combined with the Spark platform, a hybrid particle swarm algorithm that will be parallelized is proposed. Compared with the existing intelligent algorithms, the parallel hybrid particle swarm algorithm is more conducive to the realization of the global optimal solution. In the loader manufacturing workshop, the optimization goal is to minimize the maximum completion time and a parallelized hybrid particle swarm algorithm is used. The results show that in the case of relatively large batches, the parallel hybrid particle swarm algorithm can effectively obtain the scheduling plan and avoid falling into the local optimal solution. Compared with algorithm serialization, algorithm parallelization improves algorithm efficiency by 2–4 times. The larger the batches, the more obvious the algorithm parallelization improves computational efficiency.
Keywords	hybrid mixed-flow workshop ; hybrid particle swarm algorithm ; algorithm parallelization ; computational efficiency ; Industrial engineering. Management engineering ; T55.4-60.8 ; Electronic computers. Computer science ; QA75.5-76.95
Subject code	629
Language	English
Publishing date	2021-08-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Mass spectrometric determination of N7-HPTE-dG and N7-HPTE-Gua in mammalian cells and mice exposed to methoxychlor, an emergent persistent organic pollutant

Wu, Jiabin / Wang, Fuyue / Xie, Guangshan / Cai, Zongwei

Journal of hazardous materials. 2022 June 15, v. 432

2022

Abstract: Methoxychlor (MXC) is an organopesticide classified as a “Proposed Persistent Organic Pollutant” in the Stockholm Convention, and recent studies revealed that MXC could induce DNA strand breaks, whereas its underlying mechanisms were underinvestigated. ... ...

Abstract	Methoxychlor (MXC) is an organopesticide classified as a “Proposed Persistent Organic Pollutant” in the Stockholm Convention, and recent studies revealed that MXC could induce DNA strand breaks, whereas its underlying mechanisms were underinvestigated. Here, we first reported that hydroxymethoxychlor (HPTE), one of MXC’s active metabolites, could be oxidized in vivo to form quinone intermediate, which attacked N7 position of 2′-deoxyguanosine to form N7-HPTE-deoxyguanosine (N7-HPTE-dG), followed by depurination to produce N7-HPTE-guanine (N7-HPTE-Gua) in MXC-treated mammalian cells and tissues from mice fed with MXC, employing an ultra-performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UPLC-ESI-MS/MS) method. We observed a positive correlation between the doses of MXC exposure and the levels of N7-HPTE-Gua and N7-HPTE-dG in cytoplasm and genomic DNA, respectively. Furthermore, after removal of exogenous MXC, the amount of genomic N7-HPTE-dG was significantly decreased during 24 h, while the level of cytoplasmic N7-HPTE-Gua was elevated during first 12 h, indicating the accumulation of the N7-HPTE-Gua in cells. Additionally, for animal experiment, genomic N7-HPTE-dG was observed in livers and cortexes from female C57BL/6 mice fed with MXC, suggesting a potential mechanism of its hepatoxicity and neurotoxicity. Overall, our study provides new understanding about the formation of MXC-induced DNA adducts in mammalian cells and animal models.
Keywords	DNA adducts ; animal experimentation ; cytoplasm ; females ; genomics ; metabolites ; methoxychlor ; neurotoxicity ; persistent organic pollutants ; quinones
Language	English
Dates of publication	2022-0615
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	1491302-1
ISSN	1873-3336 ; 0304-3894
ISSN (online)	1873-3336
ISSN	0304-3894
DOI	10.1016/j.jhazmat.2022.128741
Database	NAL-Catalogue (AGRICOLA)

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