Article: Mucosale afwijkingen bij blaarvormende auto-immuunziekten.
Nederlands tijdschrift voor tandheelkunde
2023 Volume 130, Issue 5, Page(s) 237–241
Abstract: Mucosal anomalies are frequently seen in autoimmune bullous diseases, particularly in pemphigus vulgaris and mucous membrane pemphigoid. The blistering, erosions, ulceration or erythema may present anywhere on the oral mucosa, but also on other mucosal ... ...
Title translation | Mucosal anomalies in autoimmune bullous diseases. |
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Abstract | Mucosal anomalies are frequently seen in autoimmune bullous diseases, particularly in pemphigus vulgaris and mucous membrane pemphigoid. The blistering, erosions, ulceration or erythema may present anywhere on the oral mucosa, but also on other mucosal sites. A differential diagnosis is needed of (erosive) oral lichen planus, systemic autoimmune disease, inflammatory bowel diseases, chronic graft-versus-host disease, infectious causes, Behçet's syndrome and recurrent aphthous stomatitis. A quick diagnosis and initiation of adequate treatment are important because of the potential severity of the disease and to prevent complications due to cicatrization. Besides a biopsy for histopathological analysis, a perilesional biopsy for direct immunofluorescence microscopy and immunoserological tests are needed for diagnosis of pemphigus or pemphigoid. In addition to a mucosal biopsy, a biopsy for direct immunofluorescence of the skin can contribute to a diagnosis of a bullous disease. Besides topical corticosteroids, immunosuppressive treatment is often required for treating autoimmune bullous diseases, such as treatment with rituximab in patients with pemphigus. |
MeSH term(s) | Humans ; Pemphigus/diagnosis ; Pemphigus/pathology ; Pemphigoid, Bullous/diagnosis ; Pemphigoid, Bullous/pathology ; Autoimmune Diseases/diagnosis ; Autoimmune Diseases/complications ; Autoimmune Diseases/pathology ; Skin Diseases, Vesiculobullous/diagnosis ; Skin Diseases, Vesiculobullous/complications ; Skin Diseases, Vesiculobullous/pathology ; Mouth Mucosa/pathology |
Language | Dutch |
Publishing date | 2023-05-09 |
Publishing country | Netherlands |
Document type | English Abstract ; Journal Article |
ZDB-ID | 603498-6 |
ISSN | 0028-2200 |
ISSN | 0028-2200 |
DOI | 10.5177/ntvt.2023.05.22090 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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