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  1. Article ; Online: Comparison of the magnetic resonance scoring systems for Crohn's disease activity: MaRIA, simplified MaRIA, and Nancy scores.

    Lee, Wei-En / Weng, Meng-Tzu / Wei, Shu-Chen / Shih, I-Lun

    Abdominal radiology (New York)

    2023  Volume 48, Issue 7, Page(s) 2228–2236

    Abstract: ... and Nancy score for each colonic segment and terminal ileum were calculated and correlated ... curve (AUC) of the MaRIA, sMaRIA, and Nancy scores for detecting active disease were 0.752, 0.764, and 0 ... a higher AUC (0.721 and 0.741) than the Nancy score (0.652) for disease monitoring.: Conclusion ...

    Abstract Purpose: The most widely used score for assessing the activity of Crohn's disease (CD) is the Magnetic Resonance Index of Activity (MaRIA) score, but it is time-consuming. The aim of this study was to compare the diagnostic accuracy of MaRIA score to the other two easily calculated scores.
    Methods: Between January 2011 and May 2021, 67 patients with CD who underwent MRE and ileocolonoscopy within 2 weeks were enrolled. The MRE-based scores including the MaRIA score, simplified MaRIA (sMaRIA) score, and Nancy score for each colonic segment and terminal ileum were calculated and correlated with the ileocolonoscopic findings. The simplified endoscopic score for Crohn's disease (SES-CD) was considered the gold standard.
    Results: A total of 343 intestinal segments were included in the analysis, of which 109 (31.8%) showed active inflammation on ileocolonoscopy. The areas under the receiver operating characteristic curve (AUC) of the MaRIA, sMaRIA, and Nancy scores for detecting active disease were 0.752, 0.764, and 0.765, respectively. In the sub-analysis for different indications, the MaRIA and sMaRIA scores showed a higher AUC (0.721 and 0.741) than the Nancy score (0.652) for disease monitoring.
    Conclusion: The sMARIA and Nancy scores showed comparable diagnostic accuracy to the MaRIA score, and thus could be used as alternatives to the MaRIA score. Furthermore, considering the range of application, especially for disease monitoring, the sMaRIA score may be more suitable for use in clinical practice.
    MeSH term(s) Humans ; Crohn Disease/pathology ; Severity of Illness Index ; Magnetic Resonance Imaging ; Magnetic Resonance Spectroscopy ; Colon/pathology
    Language English
    Publishing date 2023-05-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2839786-1
    ISSN 2366-0058 ; 2366-004X
    ISSN (online) 2366-0058
    ISSN 2366-004X
    DOI 10.1007/s00261-023-03926-w
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  2. Article ; Online: "

    Chen, Xiang / Du, Yi-Chieh Nancy

    Annals of pancreatic cancer

    2022  Volume 5

    Language English
    Publishing date 2022-07-10
    Publishing country China
    Document type Journal Article ; Comment
    ISSN 2616-2741
    ISSN (online) 2616-2741
    DOI 10.21037/apc-2022-1
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  3. Article ; Online: A gene for color differences between sexes.

    Chen, Nancy

    Science (New York, N.Y.)

    2020  Volume 368, Issue 6496, Page(s) 1185–1186

    MeSH term(s) Animals ; Birds ; Pigmentation ; Sex Characteristics
    Language English
    Publishing date 2020-11-12
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.abc2242
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  4. Article ; Online: Exploring and contextualizing the associations among political identification, vaccine risk and benefit perceptions, and vaccine acceptance.

    Chen, Nien-Tsu Nancy

    Risk analysis : an official publication of the Society for Risk Analysis

    2023  Volume 44, Issue 5, Page(s) 1219–1236

    Abstract: There is considerable research on the influence of political partisanship on vaccine acceptance. However, the current study is one of the first to investigate how political identification is related to risk and benefit perceptions vis-à-vis vaccines. ... ...

    Abstract There is considerable research on the influence of political partisanship on vaccine acceptance. However, the current study is one of the first to investigate how political identification is related to risk and benefit perceptions vis-à-vis vaccines. Based on survey data collected in the United States regarding four different vaccines at three points in time (n = 383 for April-June 2012; n = 364 for March 2020; n = 334 for April-May 2020), Democrats were found to have more positive attitudes toward vaccinations in general and hold more favorable risk and benefit perceptions of pandemic and routine vaccines overall compared to Republicans. However, the onset of a pandemic can serve as an equalizing force and motivate similar risk and benefit perceptions across party lines, but this force can wane quickly when the information environment is politicized. For political partisans who are ideologically oriented to be more hesitant toward vaccines, two conditions can help sustain their favorable vaccine perceptions during a pandemic: (a) when they identify with the governing political party, and (b) when there are consistent reassurances of vaccine safety and effectiveness from their partisan leadership. Given that risk and benefit perceptions were found to be consistently associated with vaccine acceptance across contexts in this study, communication aimed at encouraging vaccinations should always address the risks and benefits of a vaccine in ways that are tailored for individuals with different political affiliations.
    Language English
    Publishing date 2023-09-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 778660-8
    ISSN 1539-6924 ; 0272-4332
    ISSN (online) 1539-6924
    ISSN 0272-4332
    DOI 10.1111/risa.14220
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  5. Article ; Online: A case series of thyroid fine needle aspiration biopsies diagnosed as follicular neoplasm with oncocytic features.

    Chen, Constance V / Krishnan, Vimal / Greenland, Nancy Y

    Diagnostic cytopathology

    2024  

    Abstract: Oncocytic lesions of the thyroid are a heterogeneous group encompassing nonneoplastic and neoplastic entities ranging from benign to malignant and have traditionally been classified as separate entities in thyroid pathology. To illustrate the diversity ... ...

    Abstract Oncocytic lesions of the thyroid are a heterogeneous group encompassing nonneoplastic and neoplastic entities ranging from benign to malignant and have traditionally been classified as separate entities in thyroid pathology. To illustrate the diversity of these thyroid lesions, we describe three cases of fine needle aspiration biopsies (FNAB) diagnosed as Bethesda Category IV: Follicular neoplasm, oncocytic type, under the 2017 Bethesda System for Reporting Thyroid Cytopathology (TBSRTC), with ThyroSeq v3 molecular testing and subsequent surgical excision.
    Language English
    Publishing date 2024-04-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 632710-2
    ISSN 1097-0339 ; 8755-1039
    ISSN (online) 1097-0339
    ISSN 8755-1039
    DOI 10.1002/dc.25314
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  6. Article ; Online: Conservation: Bye-Bye to the Hihi?

    Chen, Nancy

    Current biology : CB

    2019  Volume 29, Issue 6, Page(s) R218–R220

    Abstract: Theoretically, small populations should be less capable of adapting to environmental change, yet empirical evidence is mixed. A new study on a rare New Zealand bird, the Hihi, uses genomics and long-term demographic data to reveal low adaptive potential. ...

    Abstract Theoretically, small populations should be less capable of adapting to environmental change, yet empirical evidence is mixed. A new study on a rare New Zealand bird, the Hihi, uses genomics and long-term demographic data to reveal low adaptive potential.
    MeSH term(s) Adaptation, Physiological ; Animals ; Environment ; New Zealand ; Passeriformes/physiology
    Language English
    Publishing date 2019-03-18
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1071731-6
    ISSN 1879-0445 ; 0960-9822
    ISSN (online) 1879-0445
    ISSN 0960-9822
    DOI 10.1016/j.cub.2019.02.013
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  7. Article: Satisfaction with Teleophthalmology Services: Insights from Remote Areas of Taiwan.

    Chen, Nancy / Wang, Jen-Hung / Chiu, Cheng-Jen

    Healthcare (Basel, Switzerland)

    2024  Volume 12, Issue 8

    Abstract: During and after the COVID-19 pandemic, teleophthalmology provided access to eye care for rural populations. This study aimed to assess the efficacy of and satisfaction with an integrated real-time videoconferencing module. This project incorporated ... ...

    Abstract During and after the COVID-19 pandemic, teleophthalmology provided access to eye care for rural populations. This study aimed to assess the efficacy of and satisfaction with an integrated real-time videoconferencing module. This project incorporated ophthalmic instruments and telecommunication devices and provided on-site consultations via videoconferencing. Both patients and healthcare providers completed satisfaction questionnaires. From May 2020 to May 2021, this project provided eye care services to 395 patients (aged 6-90 years). The most frequent eye condition was chronic conjunctivitis (n = 197), followed by senile cataract (n = 163), dry eye (n = 103), and refractive error (n = 95). Among them, 40 (10.1%) patients were referred to secondary or tertiary hospitals for further evaluation or treatment. In total, 181 recruited respondents provided good satisfaction scores in all dimensions, including quality of medical care (4.50 of 5.00), financial aspects of care (4.48), supportive attitude toward the project (4.47), quality of service (4.40), and quality of telecommunication (4.40). Women had a substantially more supportive attitude toward the project, and 25 healthcare providers provided low ratings in areas representing the quality of telecommunication (4.04) and user-friendliness of the instrument (4.00). This teleophthalmology system provided efficient and satisfactory eye care to participants in remote communities. However, better internet access and training in instrument use can reduce obstacles to the future implementation of the project.
    Language English
    Publishing date 2024-04-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare12080818
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  8. Article ; Online: A happiness approach to valuing health states for children.

    Huang, Li / Devlin, Nancy / Chen, Gang / Dalziel, Kim

    Social science & medicine (1982)

    2024  Volume 348, Page(s) 116802

    Abstract: Preference weights are widely used to score generic health states into utility indexes for estimation of quality adjusted life years (QALYs) and to aid health care funding decisions. To date, health state utilities are predominantly derived using stated ... ...

    Abstract Preference weights are widely used to score generic health states into utility indexes for estimation of quality adjusted life years (QALYs) and to aid health care funding decisions. To date, health state utilities are predominantly derived using stated preference methods based on decision utility. This paper tests an alternative and generates preference weights using experienced utility for children based on the Child Health Utility 9D (CHU9D) descriptive system. We estimate the relative values of the CHU9D health states with regard to experienced utility, where experienced utility is approximated by self-reported happiness. A nationally-representative longitudinal survey was used including 6090 Australian children aged 12-17 years surveyed over 2014-2018. The derived weights were then applied to calculate the utility decrements for a few common child health conditions. We found that the estimated utility decrements are largely similar to those estimated using the published CHU9D Australian adolescent weights based on decision utility, except for pain and depression. A smaller utility decrement for pain and a larger utility decrement for depression were indicated by experienced utility. We contribute to the literature by showing that using experienced utility methods to generate preference weights for health states is possible, and we discuss some important methodological challenges for future studies such as the impracticability of anchoring to 'dead' when utilizing experienced utility.
    MeSH term(s) Humans ; Child ; Happiness ; Adolescent ; Female ; Male ; Australia ; Health Status ; Longitudinal Studies ; Quality-Adjusted Life Years ; Child Health
    Language English
    Publishing date 2024-03-26
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 4766-1
    ISSN 1873-5347 ; 0037-7856 ; 0277-9536
    ISSN (online) 1873-5347
    ISSN 0037-7856 ; 0277-9536
    DOI 10.1016/j.socscimed.2024.116802
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  9. Article ; Online: The Longitudinal Dyadic Associations Between Social Participation and Cognitive Function in Older Chinese Couples.

    Hou, Jianhua / Chen, Tianyong / Yu, Nancy Xiaonan

    The journals of gerontology. Series B, Psychological sciences and social sciences

    2024  Volume 79, Issue 6

    Abstract: Objectives: Based on the "linked lives" tenant of the life course perspective, this longitudinal study aims to examine the actor and partner effects of social participation on cognitive function in older Chinese couples.: Methods: A total of 1,706 ... ...

    Abstract Objectives: Based on the "linked lives" tenant of the life course perspective, this longitudinal study aims to examine the actor and partner effects of social participation on cognitive function in older Chinese couples.
    Methods: A total of 1,706 couples aged 60 and older were included in the final analyses. Social participation was measured using 2 questions regarding types of activities and frequency. Cognitive function was measured using a combination of memory, orientation, visuoconstruction, attention, and calculation. The lagged-dependent APIM was used to model the dyadic associations between social participation and cognitive function.
    Results: The time-averaged actor effects of both husbands' and wives' social participation on their own cognitive function were significant (p < .001 for both). The time-averaged partner effect of husbands' social participation on wives' cognitive function was significant (p < .001) but the reverse-the effect of wives' social participation on husbands' cognitive function-was not (p = .381). The time-specific actor and partner effects were not significant (p > .05 for all).
    Discussion: Our findings indicate an asymmetrical pattern of actor-partner interdependence, where husbands' social participation may affect their wives' cognitive function on average, but wives' social participation does not affect their husbands' cognitive function. Clinical practitioners should invite both partners, especially husbands, to participate in social participation interventions to facilitate crossover benefits for wives. Moreover, policymakers should build more facilities to encourage older couples to engage in social activities to prevent cognitive decline.
    MeSH term(s) Humans ; Male ; Social Participation/psychology ; Female ; Aged ; Longitudinal Studies ; China ; Spouses/psychology ; Cognition ; Middle Aged ; Aged, 80 and over ; Aging/psychology ; Interpersonal Relations ; East Asian People
    Language English
    Publishing date 2024-04-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1223664-0
    ISSN 1758-5368 ; 1079-5014
    ISSN (online) 1758-5368
    ISSN 1079-5014
    DOI 10.1093/geronb/gbae045
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  10. Article ; Online: Maternal autonomy support and intrusive control in the United States and China: Moment-to-moment associations with preschoolers' agency and defeat.

    Chen, Xi / McElwain, Nancy L / Pomerantz, Eva M / Wang, Mengjiao

    Developmental psychology

    2024  

    Abstract: This study examines the moment-to-moment within-person associations between maternal and child behaviors during a challenging puzzle task and compares these associations between mother-child dyads from the United States ( ...

    Abstract This study examines the moment-to-moment within-person associations between maternal and child behaviors during a challenging puzzle task and compares these associations between mother-child dyads from the United States (
    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2066223-3
    ISSN 1939-0599 ; 0012-1649
    ISSN (online) 1939-0599
    ISSN 0012-1649
    DOI 10.1037/dev0001723
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