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Article ; Online: Integrating satellite and reanalysis precipitation products for SWAT hydrological simulation in the Jing River Basin, China.

Zhang, Yangkai / Gao, Yang / Xu, Liujia / Liu, Zhengguang / Wu, Lei

Environmental science and pollution research international

2024 Volume 31, Issue 13, Page(s) 20534–20555

Abstract: In hydrological studies, satellite and reanalysis precipitation products are increasingly being used to supplement gauge observation data. This study designed the composite simulation index (COSI), considering two factors: F1 (data accuracy assessment) ... ...

Abstract	In hydrological studies, satellite and reanalysis precipitation products are increasingly being used to supplement gauge observation data. This study designed the composite simulation index (COSI), considering two factors: F1 (data accuracy assessment) and F2 (hydrological simulation performance), to compare the performance of the latest satellite-based and reanalysis-based precipitation products (IMERG, ERA5, ERA5-Land), the prior precipitation products (TRMM, CMADS), and the multi-source weighted-ensemble precipitation (MSWEP). The Soil and Water Assessment Tool (SWAT) model was then applied to compare and analyze the hydrological simulation performance of four preferred products using three data fusion methods including simple model averaging, variance-based weighted averaging, and the latest quantile-based Bayesian model averaging (QBMA). The results can be summarized as follows: (1) Reanalysis products are superior to satellite-based products in terms of F1. However, the satellite-based precipitation products exhibit less BIAS and relatively higher F2, while the MSWEP has relatively high performance on both F1 and F2. (2) Among reanalysis-based precipitation products, CMADS has the best COSI value of 0.53. Although ERA5-Land shows good performance for individual parameters, the comprehensive assessment reveals that ERA5 outperforms ERA5-Land in terms of both F1 and F2. (3) IMERG and TRMM exhibit similar spatiotemporal patterns and similar F1, but IMERG is superior in F2. (4) QBMA outperformed traditional methods in F2, improving the NS coefficient of SWAT model from 0.74 to 0.85. These findings provide a useful reference for analyzing the strengths and limitations of satellite-based and reanalysis precipitation products, and also provide valuable ideas for the combined application of multi-source precipitation products in hydrological studies.
MeSH term(s)	Soil ; Rivers ; Bayes Theorem ; Hydrology ; China
Chemical Substances	Soil
Language	English
Publishing date	2024-02-20
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-024-32482-z
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Article ; Online: Polygonatum sibiricum (Huang Jing) polysaccharide reduces diabetic cardiomyopathy through increasing cyclic guanosine monophosphate-protein kinase G signaling in diabetic mice.

Lei, Shengping / Lu, Xin / Yan, Lei / Liu, Tian / Niu, Yan / Yu, Jun

Journal of diabetes investigation

2024

Abstract: ... with diabetes, and is associated with a high mortality rate. The anti-oxidant properties of Jing Huang or ...

Abstract	Aims/introduction: Diabetic cardiomyopathy (DCM) is a prevalent condition among individuals with diabetes, and is associated with a high mortality rate. The anti-oxidant properties of Jing Huang or Polygonatum sibiricum polysaccharide (PSP) have been extensively used to treat diabetes-related disorders; however, its potential effectiveness against DCM remains unknown. This study aimed to investigate PSP's therapeutic effects on DCM in an experimental diabetic mouse model. Materials and methods: To induce insulin resistance, mice were fed a high-fat diet for 3 months, followed by intraperitoneal streptozotocin injection to induce slight hyperglycemia and develop DCM. Both DCM and control mice were given PSP orally for 3 weeks. Western blotting was used to detect the protein expressions of protein kinase G, C/EBP homologous protein, glucose-regulated protein 78, phosphodiesterase type 5, protein kinase R-like endoplasmic reticulum (ER) kinase, and phospho-protein kinase R-like endoplasmic reticulum kinase in heart tissue. Results: The results showed a reduction in bodyweight and blood glucose levels in the PSP therapy group compared with DCM group. PSP also improved cardiac function and had a negligible effect on malondialdehyde activity. Furthermore, the findings showed that PSP alleviated ER and oxidative stress observed in DCM mice hearts, leading to the inhibition of cyclic guanosine monophosphate-specific phosphodiesterase type 5 and cardiac cyclic guanosine monophosphate reactivation. Phosphodiesterase type 5 inhibition reduced high-fat diet-induced cardiac dysfunction and decreased ER stress. Conclusions: PSP could effectively protect diabetic myocardium by inhibiting endoplasmic reticulum stress. These findings provide crucial insights into the potential of PSP to ameliorate DCM conditions in diabetic mice by decreasing ER and oxidative stress, and enhancing cyclic guanosine monophosphate protein kinase G signaling.
Language	English
Publishing date	2024-03-29
Publishing country	Japan
Document type	Journal Article
ZDB-ID	2625840-7
ISSN	2040-1124 ; 2040-1116
ISSN (online)	2040-1124
ISSN	2040-1116
DOI	10.1111/jdi.14192
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Article ; Online: Identification of nitrate sources in the Jing River using dual stable isotopes, Northwest China.

Hu, Jing / Pan, Mengyan / Han, Tianhao / Zhuang, Zhi / Cao, Yunning / Yang, Kaili / Li, Yuliang / Liu, Weiguo

Environmental science and pollution research international

2021 Volume 28, Issue 48, Page(s) 68633–68641

Abstract: ... Nitrate ( ... ...

Abstract	Nitrate (NO
MeSH term(s)	Bayes Theorem ; China ; Environmental Monitoring ; Nitrates/analysis ; Nitrogen Isotopes/analysis ; Rivers ; Water Pollutants, Chemical/analysis
Chemical Substances	Nitrates ; Nitrogen Isotopes ; Water Pollutants, Chemical
Language	English
Publishing date	2021-07-17
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-021-15380-6
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Article ; Online: Effect of Yi Jin Jing exercise plus Elastic Band Resistance exercise on overall bone mineral density in postmenopausal women.

Li, Jingyuan / Gu, Qing / Li, Ruixue / Wang, Ru / Cai, Yanwei / Huang, Yunda / Wang, Shasha / Wang, Suijun / Liu, Xiangyun

Journal of science and medicine in sport

2023 Volume 26, Issue 2, Page(s) 87–92

Abstract: Objectives: This work aimed to study the effects of Yi Jin Jing plus Elastic Band Resistance ... their lifestyle behaviors unaltered, whereas the exercise group received  Yi Jin Jing plus Elastic Band Resistance ... Conclusions: The results suggested that Yi Jin Jing plus Elastic Band Resistance exercise could delay ...

Abstract	Objectives: This work aimed to study the effects of Yi Jin Jing plus Elastic Band Resistance exercise on bone mineral density at all parts of the body and bone metabolism index levels in postmenopausal women. Design: Randomized controlled trial. Methods: Forty postmenopausal women were randomly assigned equally to the exercise or to the control group. The control group maintained their lifestyle behaviors unaltered, whereas the exercise group received  Yi Jin Jing plus Elastic Band Resistance exercise. The primary outcome was overall bone mineral density at each part, and the secondary one was bone metabolism indicator levels and bone mineral density on both sides. Results: The results after six months showed increased bone mineral density at all parts of the body in the exercise group (spine, P = 0.002; thighs, lumbar, and whole body, P < 0.05) and decreased bone mineral density in the control group (trunk, pelvis, and spine, P < 0.01). In particular, the decrease and increase were greater on the non-preferred (left) side than on the right side. As for bone metabolism indexes, β-Crosslaps levels reduced (P = 0.016) and a significant increase in 1,25-(OH)2-D3 (P < 0.001) can be observed in the exercise group. Conclusions: The results suggested that Yi Jin Jing plus Elastic Band Resistance exercise could delay the overall decrease of bone mineral density in postmenopausal women, especially on the non-preferred side. It also increased bone formation metabolite levels and inhibited bone resorption metabolite levels.
MeSH term(s)	Humans ; Female ; Bone Density ; Postmenopause ; Resistance Training ; Exercise ; Spine
Language	English
Publishing date	2023-01-14
Publishing country	Australia
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	1437829-2
ISSN	1878-1861 ; 1440-2440
ISSN (online)	1878-1861
ISSN	1440-2440
DOI	10.1016/j.jsams.2023.01.006
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Article: Tong Jing Yi Hao Formula Alleviates Ornidazole-Induced Oligoasthenospermia in Rats by Suppressing ROS/MAPK/HIF-1 Pathway.

Tian, Zhaohui / Liu, Jia / Zeng, Mingyue / Zeng, Qingqi

Archivos espanoles de urologia

2023 Volume 76, Issue 8, Page(s) 596–604

Abstract: Background: Tong Jing Yi Hao Formula (TJYHF) is a Traditional Chinese medicine used ...

Abstract	Background: Tong Jing Yi Hao Formula (TJYHF) is a Traditional Chinese medicine used for oligoasthenospermia (OAS) treatment. However, the role of TJYHF against OAS is unclear. This study was an initial attempt to solve this problem. Methods: Rats were randomly allocated to normal, ornidazole (Orn), levocarnitine (450 mg/kg), low-dose TJYHF (6.5 g/kg) and high-dose TJYHF (26 g/kg) groups, each consisting of six rats. Oral administration of Orn (400 mg/kg) for 4 weeks was used to induce OAS, followed by oral doses of the respective drugs for an additional 4 weeks. Parameters, including the testicular index, epididymis index, testicular volume, sperm parameters, sex hormone levels, histological changes and markers of oxidative stress, were evaluated to assess the effects of treatment. The potential mechanism involved in the therapeutic effects of TJYHF was studied by evaluating the activity and expression levels of key molecules within the reactive oxygen species (ROS)/mitogen-activated protein kinase (MAPK)/hypoxia-inducible factor 1 (HIF-1) pathway. Results: Compared with healthy rats, the Orn-induced rats demonstrated decreases in testicular index, epididymis index, testicular volume, sperm concentration, total sperm count, percentage of forwarding sperm motility, total sperm motility, testosterone, spermatogenic epithelium, reproductive cell, glutathione peroxidase, superoxide dismutase and glutathione and increases in sperm deoxyribonucleic acid fragmentation index, follicle-stimulating hormone, luteinizing hormone and malondialdehyde. In the testicles, an enhancement in the ROS level and phosphorylation levels of extracellular signal-regulated kinase 1/2 (ERK1/2), c-jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (p38) was observed after Orn challenge. Moreover, the protein expression levels and immunostaining intensity of p38 and HIF-1α increased, indicating the activation of the ROS/MAPK/HIF-1 pathway. All of the aforementioned changes exhibited statistical significance ( Conclusions: TJYHF exerted a beneficial effect on reproductive function in OAS rats through the inhibition of the ROS/MAPK/HIF-1 pathway.
MeSH term(s)	Animals ; Male ; Rats ; Ornidazole/pharmacology ; Reactive Oxygen Species/metabolism ; Reactive Oxygen Species/pharmacology ; Semen/metabolism ; Sperm Motility ; Testis/metabolism ; Oligospermia/chemically induced
Chemical Substances	Ornidazole (62XCK0G93T) ; Reactive Oxygen Species
Language	English
Publishing date	2023-11-13
Publishing country	Spain
Document type	Journal Article
ZDB-ID	211673-x
ISSN	0004-0614
ISSN	0004-0614
DOI	10.56434/j.arch.esp.urol.20237608.74
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Article ; Online: Jing-Fang powder ethyl acetate extracts attenuate atopic dermatitis by modulating T-cell activity.

Zhao, Ge / Tong, Yue / Xu, Jie / Zhu, Wenjing / Zeng, Jiuseng / Liu, Rong / Luan, Fei / Zeng, Nan

Molecular immunology

2023 Volume 160, Page(s) 133–149

Abstract: Jing-Fang powder ethyl acetate extract (JFEE) and its isolated C (JFEE-C) possess favorable ...

Abstract	Jing-Fang powder ethyl acetate extract (JFEE) and its isolated C (JFEE-C) possess favorable anti-inflammatory and anti-allergic properties; however, their inhibitory effects on T cell activity remain unknown. In vitro, Jurkat T cells and primary mouse CD4
MeSH term(s)	Animals ; Mice ; Dermatitis, Atopic/drug therapy ; Dermatitis, Atopic/chemically induced ; Interleukin-2 ; Powders/adverse effects ; Powders/metabolism ; NF-kappa B/metabolism ; Cytokines/metabolism ; CD4-Positive T-Lymphocytes/metabolism ; Mice, Inbred BALB C ; Plant Extracts/pharmacology
Chemical Substances	Interleukin-2 ; ethyl acetate (76845O8NMZ) ; Powders ; NF-kappa B ; Cytokines ; Plant Extracts
Language	English
Publishing date	2023-07-08
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	424427-8
ISSN	1872-9142 ; 0161-5890
ISSN (online)	1872-9142
ISSN	0161-5890
DOI	10.1016/j.molimm.2023.07.002
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Article ; Online: Pen Yan Jing Tablets Alleviates Pelvic Inflammatory Disease by Inhibiting Akt/NF-κB Pathway.

Tang, Ping / Ding, Qi / Lin, Juan / Yang, Xinrong / Wang, Yiting / Liu, Fangle / Zheng, Yuying / Lin, Liuqing / Wang, Deqin / Lin, Baoqin

International journal of medical sciences

2023 Volume 20, Issue 11, Page(s) 1386–1398

Abstract: Purpose: ...

Abstract	Purpose:
MeSH term(s)	Humans ; Female ; Rats ; Animals ; NF-kappa B/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction ; NF-KappaB Inhibitor alpha/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Pelvic Inflammatory Disease/drug therapy ; Lipopolysaccharides/pharmacology ; Interleukin-6 ; Intercellular Adhesion Molecule-1/metabolism ; Vascular Cell Adhesion Molecule-1/metabolism ; Vascular Cell Adhesion Molecule-1/pharmacology ; Cyclooxygenase 2/metabolism
Chemical Substances	NF-kappa B ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; NF-KappaB Inhibitor alpha (139874-52-5) ; Tumor Necrosis Factor-alpha ; Lipopolysaccharides ; Interleukin-6 ; Intercellular Adhesion Molecule-1 (126547-89-5) ; Vascular Cell Adhesion Molecule-1 ; Cyclooxygenase 2 (EC 1.14.99.1)
Language	English
Publishing date	2023-09-04
Publishing country	Australia
Document type	Journal Article
ZDB-ID	2151424-0
ISSN	1449-1907 ; 1449-1907
ISSN (online)	1449-1907
ISSN	1449-1907
DOI	10.7150/ijms.87433
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Article ; Online: Correction: Comparative effectiveness of aerobic exercise versus Yi Jin Jing on ovarian function in young overweight/obese women with polycystic ovary syndrome: study protocol for a randomized controlled trial.

Zhao, Jing / Ketlhoafetse, Antonnette / Liu, Xiangyun / Cao, Yang

Trials

2022 Volume 23, Issue 1, Page(s) 564

Language	English
Publishing date	2022-07-15
Publishing country	England
Document type	Published Erratum
ZDB-ID	2040523-6
ISSN	1745-6215 ; 1468-6694 ; 1745-6215
ISSN (online)	1745-6215
ISSN	1468-6694 ; 1745-6215
DOI	10.1186/s13063-022-06547-8
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Article ; Online: Comparative effectiveness of aerobic exercise versus Yi Jin Jing on ovarian function in young overweight/obese women with polycystic ovary syndrome: study protocol for a randomized controlled trial.

Zhao, Jing / Ketlhoafetse, Antonnette / Liu, Xiangyun / Cao, Yang

Trials

2022 Volume 23, Issue 1, Page(s) 459

Abstract: ... an important solution used to manage PCOS, due to its multiple benefits. Yi Jin Jing is an important component ... on the benign effects of Yi Jin Jing on PCOS. The primary purpose of this protocol is to assess ... the effectiveness of aerobic exercise versus Yi Jin Jing, on the management of ovarian function in young overweight ...

Abstract	Background: Polycystic ovary syndrome (PCOS) is the most common heterogeneous endocrine disease among women of childbearing age, characterized by androgen excess and ovarian dysfunction. Aerobic exercise is an important solution used to manage PCOS, due to its multiple benefits. Yi Jin Jing is an important component of traditional Chinese exercise (TCE), based on the root of traditional Chinese medicine theory (TCM), which focuses on keeping the body as a whole in a harmonious state. However, to date there is no literature on the benign effects of Yi Jin Jing on PCOS. The primary purpose of this protocol is to assess the effectiveness of aerobic exercise versus Yi Jin Jing, on the management of ovarian function in young overweight/obese women with PCOS. Methods: The study will conduct a controlled randomized, superiority trial with three-arm parallel groups, recruiting 90 women diagnosed with PCOS, ages between 18 and 35 years, with a body mass index (BMI) ≥ 23 kg/m Discussion: This proposed study will be the first randomized clinical trial to evaluate the comparative effectiveness of aerobic exercise versus Yi Jin Jing on the management of ovarian function in young overweight/obese women with PCOS. The results may provide a new evidence-based management strategy for young women with PCOS. Trial registration: Chinese Clinical Trial Registry ChiCTR1900022385 . Registered on 9 April 2019.
MeSH term(s)	Adolescent ; Adult ; Anti-Mullerian Hormone ; Exercise ; Female ; Humans ; Obesity/complications ; Obesity/diagnosis ; Obesity/therapy ; Overweight/complications ; Overweight/diagnosis ; Overweight/therapy ; Polycystic Ovary Syndrome/complications ; Polycystic Ovary Syndrome/diagnosis ; Polycystic Ovary Syndrome/therapy ; Randomized Controlled Trials as Topic ; Young Adult
Chemical Substances	Anti-Mullerian Hormone (80497-65-0)
Language	English
Publishing date	2022-06-03
Publishing country	England
Document type	Clinical Trial Protocol ; Journal Article
ZDB-ID	2040523-6
ISSN	1745-6215 ; 1468-6694 ; 1745-6215
ISSN (online)	1745-6215
ISSN	1468-6694 ; 1745-6215
DOI	10.1186/s13063-022-06377-8
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Article: Mechanisms of Cong Rong Shu Jing Compound Effects on Endoplasmic Reticulum Stress in a Rat Model of Parkinson's Disease.

Lin, Yao / Tang, Lanfang / Huang, Peizhen / Liu, Ting / Zhong, Jianan / Xu, Qian / Li, Xiyu / Lin, Youning / Xiao, Shaojian / Cai, Jing

Evidence-based complementary and alternative medicine : eCAM

2020 Volume 2020, Page(s) 1818307

Abstract: This study investigated the effects of the Cong Rong Shu Jing (CRSJ) compound ...

Abstract	This study investigated the effects of the Cong Rong Shu Jing (CRSJ) compound on endoplasmic reticulum stress in a rat model of Parkinson's disease (PD). A total of 40 rats were subcutaneously injected with rotenone-sunflower oil emulsion into the back of the neck to establish a rat model of PD. These PD rats were randomly divided into low-, medium-, and high-dose groups (intragastric administration of 0.5, 1, and 2 g/kg CRSJ, respectively) and a model group (intragastric administration of the solvent; 10 rats per group). Furthermore, 10 rats each were attributed to the control and vehicle groups (both received intragastric administration of the CRSJ solvent, and the vehicle group were injected additionally with sunflower oil alone). A traction test was conducted two times, after the PD model establishment and after 14 days of CRSJ gavage. The numbers of tyrosine hydroxylase- (TH-) positive cells and the dopamine levels in the substantia nigra were assessed using immunohistochemistry and high-performance liquid chromatography, respectively. Western blotting detected the expression levels of
Language	English
Publishing date	2020-05-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	2171158-6
ISSN	1741-4288 ; 1741-427X
ISSN (online)	1741-4288
ISSN	1741-427X
DOI	10.1155/2020/1818307
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