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  1. Article ; Online: The NEWTON-g Gravity Imager

    Carbone, D. / Antoni-Micollier, L. / Hammond, G. / de Zeeuw - van Dalfsen, E. / Rivalta, E. / Bonadonna, C. / Messina, A. / Lautier-Gaud, J. / Toland, K. / Koymans, M. / Anastasiou, K. / Bramsiepe, S. / Cannavò, F. / Contrafatto, D. / Frischknecht, C. / Greco, F. / Marocco, G. / Middlemiss, R. / Ménoret, V. /
    Noack, A. / Passarelli, L. / Paul, D. / Prasad, A. / Siligato, G. / Vermeulen, P.

    Frontiers in Earth Science

    Toward New Paradigms for Terrain Gravimetry

    2020  

    Abstract: ... of energy resources (e.g., hydrocarbons and geothermal energy), management of water resources, and assessment ... of hazard (e.g., volcanic eruptions). Gravimetry is highly attractive because it can detect changes ... of this geophysical method. The NEWTON-g project proposes aradical change of paradigm for gravimetry ...

    Abstract Knowledge of the spatio-temporal changes in the characteristics and distribution of subsurface fluids is key to properly addressing important societal issues, including: sustainable management of energy resources (e.g., hydrocarbons and geothermal energy), management of water resources, and assessment of hazard (e.g., volcanic eruptions). Gravimetry is highly attractive because it can detect changes in subsurface mass, thus providing a window into processes that involve deep fluids. However, high cost and operating features associated with current instrumentation seriously limits the practical field use of this geophysical method. The NEWTON-g project proposes aradical change of paradigm for gravimetry through the development of a field-compatible measuring system (the gravity imager), able to real-time monitor the evolution of the subsurface mass changes. This system includes an array of low-costs microelectromechanical systems-based relative gravimeters, anchored on an absolute quantum gravimeter. It will provide imaging of gravity changes, associated with variations in subsurface fluid properties, with unparalleled spatio-temporal resolution. During the final ∼2 years of NEWTON-g, the gravity imager will be field tested in the summit of Mt. Etna volcano (Italy), where frequent gravity fluctuations, easy access to the active structures and the presence of a multiparameter monitoring system (including traditional gravimeters) ensure an excellent natural laboratory for testing the new tools. Insights from the gravity imager will be used to i) improve our knowledge of the cause-effect relationships between volcanic processes and gravity changes observable at the surface and ii) develop strategies to best incorporate the gravity data into hazards assessments and mitigation plans. A successful implementation of NEWTON-g will open new doors for geophysical exploration.
    Subject code 550
    Language English
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: The NEWTON-g Gravity Imager

    D. Carbone / L. Antoni-Micollier / G. Hammond / E. de Zeeuw - van Dalfsen / E. Rivalta / C. Bonadonna / A. Messina / J. Lautier-Gaud / K. Toland / M. Koymans / K. Anastasiou / S. Bramsiepe / F. Cannavò / D. Contrafatto / C. Frischknecht / F. Greco / G. Marocco / R. Middlemiss / V. Ménoret /
    A. Noack / L. Passarelli / D. Paul / A. Prasad / G. Siligato / P. Vermeulen

    Frontiers in Earth Science, Vol

    Toward New Paradigms for Terrain Gravimetry

    2020  Volume 8

    Abstract: ... of energy resources (e.g., hydrocarbons and geothermal energy), management of water resources, and assessment ... of hazard (e.g., volcanic eruptions). Gravimetry is highly attractive because it can detect changes ... of this geophysical method. The NEWTON-g project proposes a radical change of paradigm for gravimetry ...

    Abstract Knowledge of the spatio-temporal changes in the characteristics and distribution of subsurface fluids is key to properly addressing important societal issues, including: sustainable management of energy resources (e.g., hydrocarbons and geothermal energy), management of water resources, and assessment of hazard (e.g., volcanic eruptions). Gravimetry is highly attractive because it can detect changes in subsurface mass, thus providing a window into processes that involve deep fluids. However, high cost and operating features associated with current instrumentation seriously limits the practical field use of this geophysical method. The NEWTON-g project proposes a radical change of paradigm for gravimetry through the development of a field-compatible measuring system (the gravity imager), able to real-time monitor the evolution of the subsurface mass changes. This system includes an array of low-costs microelectromechanical systems-based relative gravimeters, anchored on an absolute quantum gravimeter. It will provide imaging of gravity changes, associated with variations in subsurface fluid properties, with unparalleled spatio-temporal resolution. During the final ∼2 years of NEWTON-g, the gravity imager will be field tested in the summit of Mt. Etna volcano (Italy), where frequent gravity fluctuations, easy access to the active structures and the presence of a multiparameter monitoring system (including traditional gravimeters) ensure an excellent natural laboratory for testing the new tools. Insights from the gravity imager will be used to i) improve our knowledge of the cause-effect relationships between volcanic processes and gravity changes observable at the surface and ii) develop strategies to best incorporate the gravity data into hazards assessments and mitigation plans. A successful implementation of NEWTON-g will open new doors for geophysical exploration.
    Keywords time gravity changes ; gravimetry ; gravimeter ; volcano monitoring network ; forward modelling of gravity anomalies ; Science ; Q
    Subject code 550
    Language English
    Publishing date 2020-10-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
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  3. Article: Comment to "Effect of primary tumor extirpation in breast cancer patients who present with stage IV disease and intact primary tumor" by G V Babiera, R Rao, L Feng, F Meric-Bernstam, H M Kuerer, S E Singletary, K K Hunt, M I Ross, K M Gwyn, B W Feig, F C Ames, G N Horthobagyi. Ann Surg Oncol 2006;13:776-782.

    Demicheli, Romano / Hrushesky, William J M / Retsky, Michael W / Bonadonna, Gianni / Valagussa, Pinuccia

    Annals of surgical oncology

    2007  Volume 14, Issue 4, Page(s) 1519–1520

    MeSH term(s) Bone Neoplasms/secondary ; Bone Neoplasms/surgery ; Breast Neoplasms/pathology ; Breast Neoplasms/surgery ; Disease Progression ; Female ; Humans ; Liver Neoplasms/secondary ; Liver Neoplasms/surgery ; Lung Neoplasms/secondary ; Lung Neoplasms/surgery ; Mastectomy ; Neoplasm Recurrence, Local ; Prognosis ; Survival Rate
    Language English
    Publishing date 2007-04
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-006-9279-2
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    Zs.A 4042: Show issues Location:
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  4. Article: The Potential Future of Insects in the European Food System: A Systematic Review Based on the Consumer Point of View.

    Mina, Giorgio / Peira, Giovanni / Bonadonna, Alessandro

    Foods (Basel, Switzerland)

    2023  Volume 12, Issue 3

    Abstract: Edible insects recently gained attention as a potential contributor to the future sustainability of the food system. Insect farming has indeed shown to have environmental and nutritional benefits, but edible insects are still an unusual foodstuff in ... ...

    Abstract Edible insects recently gained attention as a potential contributor to the future sustainability of the food system. Insect farming has indeed shown to have environmental and nutritional benefits, but edible insects are still an unusual foodstuff in Europe. The purpose of this article is to analyze the barriers and drivers of insect consumption in Europe and to identify the most promising strategies to convince consumers to include insect-based products in their diets. To answer these research questions, a systematic review of the literature on the consumer's point of view about insects as food was performed. The results show that the main barrier to the development of this market is related to the psychological rejection of consumers induced by disgust toward entomophagy. To break down these barriers, it is essential to increase the general knowledge about the environmental and nutritional benefits of entomophagy. Furthermore, the limited size of the edible insect market appears to be a structural barrier. Expanding the reach of the market and consumer familiarity with edible insects will increase their acceptability. Finally, some product-related strategies are also highlighted. Furthermore, this article brings new knowledge about the effectiveness of the environmental motive in convincing consumers to try edible insects.
    Language English
    Publishing date 2023-02-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12030646
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  5. Article: Molecular cloning of a human immunoglobulin G Fc receptor.

    Hibbs, M L / Bonadonna, L / Scott, B M / McKenzie, I F / Hogarth, P M

    Proceedings of the National Academy of Sciences of the United States of America

    1988  Volume 85, Issue 7, Page(s) 2240–2244

    Abstract: Human IgG Fc receptor (Fc gamma R) cDNA clones were isolated by cross-species hybridization by probing cDNA libraries with the low-affinity Fc gamma R beta 1 cDNA clone from mouse as well as a pool of oligonucleotides constructed from the nucleotide ... ...

    Abstract Human IgG Fc receptor (Fc gamma R) cDNA clones were isolated by cross-species hybridization by probing cDNA libraries with the low-affinity Fc gamma R beta 1 cDNA clone from mouse as well as a pool of oligonucleotides constructed from the nucleotide sequence of this Fc gamma R. Three cDNA clones were isolated and analysis of the predicted amino acid sequence indicated that the human Fc gamma R protein is synthesized with a 34-amino acid leader and the mature protein is composed of 281 amino acids. The extracellular region of this Fc gamma R was divided into two domains, which were very similar to each other and to the corresponding regions of both mouse alpha and beta Fc gamma Rs and showed a clear relationship to immunoglobulin variable regions. One possible N-linked glycosylation site was found in each of the extracellular domains. The human Fc gamma R leader sequence was shown to be similar to the mouse alpha Fc gamma R leader sequence, but the transmembrane region was most similar to the mouse beta 1 Fc gamma R. The intracellular domain of the human Fc gamma R was surprisingly different from both mouse Fc gamma Rs. RNA blot analysis of human cells demonstrated two transcripts (2.5 and 1.5 kilobases) that arise by use of different adenylylation signals. The cellular expression of these transcripts suggest that they encode the low-affinity p40 Fc gamma R protein.
    MeSH term(s) Amino Acid Sequence ; Animals ; Base Sequence ; DNA/genetics ; Humans ; Immunoglobulin Variable Region/genetics ; Mice/genetics ; Molecular Sequence Data ; RNA, Messenger/biosynthesis ; Receptors, Fc/biosynthesis ; Receptors, Fc/genetics ; Receptors, IgG ; Sequence Homology, Nucleic Acid
    Chemical Substances Immunoglobulin Variable Region ; RNA, Messenger ; Receptors, Fc ; Receptors, IgG ; DNA (9007-49-2)
    Language English
    Publishing date 1988-04
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.85.7.2240
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    Zs.A 1148: Show issues Location:
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  6. Article: Response of diademed sifaka (

    Bonadonna, G / Ramilijaona, O M / Raharivololona, B M / Andrianarimisa, A / Razafindraibe, H / Freeman, K / Rasambainarivo, F / Wroblewski, E E / Milich, K M

    Ecology and evolution

    2024  Volume 14, Issue 4, Page(s) e11248

    Abstract: Large-bodied mammals living in fragmented habitats are at higher risk of extinction, and such risk can be influenced by ecological factors such as predator-prey system dynamics. These dynamics can be particularly complex for conservation management when ... ...

    Abstract Large-bodied mammals living in fragmented habitats are at higher risk of extinction, and such risk can be influenced by ecological factors such as predator-prey system dynamics. These dynamics can be particularly complex for conservation management when one endangered species preys on another endangered species in an isolated or poor-quality habitat. Here we describe predation events observed over 19 months that involved two threatened species: the largest carnivore in Madagascar, the fosa (
    Language English
    Publishing date 2024-04-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2635675-2
    ISSN 2045-7758
    ISSN 2045-7758
    DOI 10.1002/ece3.11248
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  7. Article: Recombinant human interleukin-3 hastens trilineage hematopoietic recovery following high-dose (7 g/m2) cyclophosphamide cancer therapy.

    Gianni, A M / Siena, S / Bregni, M / Di Nicola, M / Peccatori, F / Magni, M / Ravagnani, F / Sklenar, I / Bonadonna, G

    Annals of oncology : official journal of the European Society for Medical Oncology

    1993  Volume 4, Issue 9, Page(s) 759–766

    Abstract: ... therapy with cyclophosphamide (7 g/m2).: Patients and methods: The growth factor, administered ... were required in interleukin 3-treated patients. In contrast to GM-CSF and G-CSF, interleukin 3 showed ...

    Abstract Background: Interleukin-3, a recombinant cytokine with multilineage stimulatory effect on hematopoietic cells, was administered to 22 previously untreated breast cancer patients following high-dose therapy with cyclophosphamide (7 g/m2).
    Patients and methods: The growth factor, administered through continuous intravenous infusion at 1 (3 patients), 2.5 (3 patients), 5 (10 patients) and 10 micrograms/kg/day (6 patients), was well tolerated up to 5 micrograms/kg/day.
    Results: Nausea, vomiting, fever and headache prevented administration of the intended dose to all 6 patients in the 10 micrograms/kg/day cohort. At the maximal tolerable dose (5 micrograms/kg/day) the growth factor significantly accelerated granulocyte, platelet and reticulocyte recovery as compared to matched historical controls who received high-dose cyclophosphamide without cytokine infusion. Moreover, no platelet transfusions and fewer erythrocyte transfusions were required in interleukin 3-treated patients. In contrast to GM-CSF and G-CSF, interleukin 3 showed no effect on the mobilization of hematopoietic progenitor cells in the peripheral blood.
    Conclusions: Interleukin-3 represents a well-tolerated cytokine, clinically useful for accelerating trilineage hematopoietic recovery following severely myelotoxic treatments such as high-dose cyclophosphamide.
    MeSH term(s) Adolescent ; Adult ; Bone Marrow/drug effects ; Breast Neoplasms/drug therapy ; Child ; Cyclophosphamide/adverse effects ; Erythrocyte Transfusion ; Female ; Granulocyte-Macrophage Colony-Stimulating Factor/therapeutic use ; Hematopoiesis/drug effects ; Humans ; Interleukin-3/adverse effects ; Interleukin-3/therapeutic use ; Male ; Middle Aged ; Recombinant Proteins/therapeutic use
    Chemical Substances Interleukin-3 ; Recombinant Proteins ; Granulocyte-Macrophage Colony-Stimulating Factor (83869-56-1) ; Cyclophosphamide (8N3DW7272P)
    Language English
    Publishing date 1993-11
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1025984-3
    ISSN 1569-8041 ; 0923-7534
    ISSN (online) 1569-8041
    ISSN 0923-7534
    DOI 10.1093/oxfordjournals.annonc.a058661
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    Zs.A 2862: Show issues Location:
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  8. Article ; Online: The fate of volcanic ash: premature or delayed sedimentation?

    Rossi, Eduardo / Bagheri, Gholamhossein / Beckett, Frances / Bonadonna, Costanza

    Nature communications

    2021  Volume 12, Issue 1, Page(s) 1303

    Abstract: A large amount of volcanic ash produced during explosive volcanic eruptions has been found to sediment as aggregates of various types that typically reduce the associated residence time in the atmosphere (i.e., premature sedimentation). Nonetheless, ... ...

    Abstract A large amount of volcanic ash produced during explosive volcanic eruptions has been found to sediment as aggregates of various types that typically reduce the associated residence time in the atmosphere (i.e., premature sedimentation). Nonetheless, speculations exist in the literature that aggregation has the potential to also delay particle sedimentation (rafting effect) even though it has been considered unlikely so far. Here, we present the first theoretical description of rafting that demonstrates how delayed sedimentation may not only occur but is probably more common than previously thought. The fate of volcanic ash is here quantified for all kind of observed aggregates. As an application to the case study of the 2010 eruption of Eyjafjallajökull volcano (Iceland), we also show how rafting can theoretically increase the travel distances of particles between 138-710 μm. These findings have fundamental implications for hazard assessment of volcanic ash dispersal as well as for weather modeling.
    Language English
    Publishing date 2021-02-26
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-021-21568-8
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  9. Article ; Online: A Review and Update on Waterborne Viral Diseases Associated with Swimming Pools.

    Bonadonna, Lucia / La Rosa, Giuseppina

    International journal of environmental research and public health

    2019  Volume 16, Issue 2

    Abstract: Infectious agents, including bacteria, viruses, protozoa, and molds, may threaten the health of swimming pool bathers. Viruses are a major cause of recreationally-associated waterborne diseases linked to pools, lakes, ponds, thermal pools/spas, rivers, ... ...

    Abstract Infectious agents, including bacteria, viruses, protozoa, and molds, may threaten the health of swimming pool bathers. Viruses are a major cause of recreationally-associated waterborne diseases linked to pools, lakes, ponds, thermal pools/spas, rivers, and hot springs. They can make their way into waters through the accidental release of fecal matter, body fluids (saliva, mucus), or skin flakes by symptomatic or asymptomatic carriers. We present an updated overview of epidemiological data on viral outbreaks, a project motivated, among other things, by the availability of improved viral detection methodologies. Special attention is paid to outbreak investigations (source of the outbreak, pathways of transmission, chlorination/disinfection). Epidemiological studies on incidents of viral contamination of swimming pools under non-epidemic conditions are also reviewed.
    MeSH term(s) Disease Outbreaks/prevention & control ; Humans ; Swimming Pools ; Virus Diseases/diagnosis ; Virus Diseases/epidemiology ; Virus Diseases/prevention & control ; Virus Diseases/transmission ; Viruses/isolation & purification ; Water Microbiology ; Waterborne Diseases/epidemiology ; Waterborne Diseases/prevention & control ; Waterborne Diseases/transmission ; Waterborne Diseases/virology
    Keywords covid19
    Language English
    Publishing date 2019-01-09
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 1660-4601
    ISSN (online) 1660-4601
    DOI 10.3390/ijerph16020166
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  10. Article ; Online: Responses of wild skuas (Catharacta antarctica ssp. lonnbergi) to human cues in cooperative and competitive social contexts.

    Danel, Samara / Rebout, Nancy / Pinto, Laura / Carette, Pierre / Bonadonna, Francesco / Biro, Dora

    Journal of comparative psychology (Washington, D.C. : 1983)

    2023  Volume 137, Issue 3, Page(s) 167–177

    Abstract: Many animals respond to and use social cues emitted by other species (e.g., head direction ...

    Abstract Many animals respond to and use social cues emitted by other species (e.g., head direction). In the context of human-animal communication, these capacities have been attributed to regular and longstanding exposure to humans. We presented wild brown skuas (Catharacta antarctica ssp. lonnbergi) with two versions of an object-choice paradigm. In the cooperative version (Experiment 1), one human experimenter provided a simple and salient cue indicating which of two containers covered a food reward. The cues administered consisted of touching, looking at, pointing at, or pointing and looking at the container hiding food. In Experiment 1, skuas could thus cooperate with an experimenter by using the cues provided to locate the rewarded container. In the competitive version (Experiment 2), two human experimenters presented a platform with a visible food reward. In six experimental conditions, we varied experimenters' body orientation, head orientation, eye-gaze direction, face occlusion, and mouth occlusion, as well as the platform's location, ensuring that in each case only one experimenter had visual access to the rewarded platform. Here, birds could compete with the experimenters by robbing the human who does not see the food. Skuas failed to use human-given cues spontaneously in Experiment 1, and took the reward regardless of whether the experimenters could see in Experiment 2. Our results contrast with those obtained on other wild birds with pre-experience with humans. Hopefully, our findings will stimulate further research in order to illuminate the potential role of such experience in the capacity to respond to and use human-given cues. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
    MeSH term(s) Animals ; Humans ; Cues ; Antarctic Regions ; Face ; Fixation, Ocular ; Social Environment
    Language English
    Publishing date 2023-08-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3130-6
    ISSN 1939-2087 ; 0735-7036 ; 0093-4127
    ISSN (online) 1939-2087
    ISSN 0735-7036 ; 0093-4127
    DOI 10.1037/com0000345
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