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Article ; Online: Ectopic thoracic parathyroid adenoma: The thoracic surgeon needs multi-approach skills!

Thumerel, Matthieu / Belaroussi, Yaniss / Tlili, Ghoufrane / Haissaguerre, Magalie / Jougon, Jacques

2024

Language	English
Publishing date	2024-03-19
Publishing country	France
Document type	Letter
ZDB-ID	299-9
ISSN	2213-3941 ; 0003-4266
ISSN (online)	2213-3941
ISSN	0003-4266
DOI	10.1016/j.ando.2024.02.002
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Article ; Online: Cervicotomy using a hemi-clamshell approach for a rare enlarged substernal goitre.

Machboua, Alia / Thumerel, Mathieu / Hustache-Castaing, Romain / Jougon, Jacques

Interactive cardiovascular and thoracic surgery

2022 Volume 35, Issue 1

Abstract: The substernal goitre is defined as a goitre for which >50% of the mass is located below the superior orifice of the thorax, surgical resection remains the reference treatment, the approach used is the cervicotomy, which often allows to extract the ... ...

Abstract	The substernal goitre is defined as a goitre for which >50% of the mass is located below the superior orifice of the thorax, surgical resection remains the reference treatment, the approach used is the cervicotomy, which often allows to extract the mediastinal portion of the plunging goitre, and we report a rare case of a huge cancerous plunging goitre whose complete resection required the enlargement of the cervicotomy in right hemi-clamshell, for the carcinological, vascular and recurrent control.
MeSH term(s)	Goiter, Substernal/complications ; Goiter, Substernal/diagnostic imaging ; Goiter, Substernal/surgery ; Humans ; Mediastinum ; Thorax
Language	English
Publishing date	2022-03-01
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2095298-3
ISSN	1569-9285 ; 1569-9293
ISSN (online)	1569-9285
ISSN	1569-9293
DOI	10.1093/icvts/ivac056
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Article ; Online: Fatal haemoptysis after a bilateral lung retransplantation 4 years ago.

Thumerel, Matthieu / Hustache, Romain / Rigaud, Matthieu / Jougon, Jacques

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

2019 Volume 55, Issue 2, Page(s) 381

Language	English
Publishing date	2019-02-21
Publishing country	Germany
Document type	Journal Article
ZDB-ID	639293-3
ISSN	1873-734X ; 1010-7940 ; 1567-4258
ISSN (online)	1873-734X
ISSN	1010-7940 ; 1567-4258
DOI	10.1093/ejcts/ezy271
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Article ; Online: Protocol for venoarterial ExtraCorporeal Membrane Oxygenation to reduce morbidity and mortality following bilateral lung TransPlantation: the ECMOToP randomised controlled trial.

Messika, Jonathan / Eloy, Philippine / Boulate, David / Charvet, Aude / Fessler, Julien / Jougon, Jacques / Lacoste, Philippe / Mercier, Olaf / Portran, Philippe / Roze, Hadrien / Sage, Edouard / Thes, Jacques / Tronc, Francois / Vourc'h, Mickael / Montravers, Philippe / Castier, Yves / Mal, Herve / Mordant, Pierre

BMJ open

2024 Volume 14, Issue 3, Page(s) e077770

Abstract: Introduction: Lung transplantation (LTx) aims at improving survival and quality of life for patients with end-stage lung diseases. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is used as intraoperative support for LTx, despite no precise ... ...

Abstract	Introduction: Lung transplantation (LTx) aims at improving survival and quality of life for patients with end-stage lung diseases. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is used as intraoperative support for LTx, despite no precise guidelines for its initiation. We aim to evaluate two strategies of VA-ECMO initiation in the perioperative period in patients with obstructive or restrictive lung disease requiring bilateral LTx. In the control 'on-demand' arm, high haemodynamic and respiratory needs will dictate VA-ECMO initiation; in the experimental 'systematic' arm, VA-ECMO will be pre-emptively initiated. We hypothesise a 'systematic' strategy will increase the number of ventilatory-free days at day 28. Methods and analysis: We designed a multicentre randomised controlled trial in parallel groups. Adult patients with obstructive or restrictive lung disease requiring bilateral LTx, without a formal indication for pre-emptive VA-ECMO before LTx, will be included. Patients with preoperative pulmonary hypertension with haemodynamic collapse, ECMO as a bridge to transplantation, severe hypoxaemia or hypercarbia will be secondarily excluded. In the systematic group, VA-ECMO will be systematically implanted before the first pulmonary artery cross-clamp. In the on-demand group, VA-ECMO will be implanted intraoperatively if haemodynamic or respiratory indices meet preplanned criteria. Non-inclusion, secondary exclusion and VA-ECMO initiation criteria were validated by a Delphi process among investigators. Postoperative weaning of ECMO and mechanical ventilation will be managed according to best practice guidelines. The number of ventilator-free days at 28 days (primary endpoint) will be compared between the two groups in the intention-to-treat population. Secondary endpoints encompass organ failure occurrence, day 28, day 90 and year 1 vital status, and adverse events. Ethics and dissemination: The sponsor is the Assistance Publique-Hôpitaux de Paris. The ECMOToP protocol version 2.1 was approved by Comité de Protection des Personnes Ile de France VIII. Results will be published in international peer-reviewed medical journals. Trial registration number: NCT05664204.
MeSH term(s)	Adult ; Humans ; Extracorporeal Membrane Oxygenation ; Quality of Life ; Lung Transplantation ; Morbidity ; Hypertension, Pulmonary/therapy ; Randomized Controlled Trials as Topic ; Multicenter Studies as Topic
Language	English
Publishing date	2024-03-05
Publishing country	England
Document type	Clinical Trial Protocol ; Journal Article
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2023-077770
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Article ; Online: Chest wall resection and reconstruction for primary and metastatic sarcomas: an 11-year retrospective cohort study.

Prisciandaro, Elena / Hustache-Castaing, Romain / Michot, Audrey / Jougon, Jacques / Thumerel, Matthieu

Interactive cardiovascular and thoracic surgery

2021 Volume 32, Issue 5, Page(s) 744–752

Abstract: Objectives: Chest wall sarcomas are rare, aggressive malignancies, the management of which mainly revolves around surgery. Radical tumour excision with free margins represents the optimal treatment for loco-regional clinically resectable disease. The ... ...

Abstract	Objectives: Chest wall sarcomas are rare, aggressive malignancies, the management of which mainly revolves around surgery. Radical tumour excision with free margins represents the optimal treatment for loco-regional clinically resectable disease. The objective of this study was to review our 11-year experience with chest wall resection for primary and metastatic sarcomas, focusing on surgical techniques and strategies for reconstruction. Methods: Retrospective analysis of a comprehensive database of patients who underwent chest wall resection for primary or secondary sarcoma at our Institute from January 2009 to December 2019. Results: Out of 26 patients, 21 (81%) suffered from primary chest wall sarcoma, while 5 (19%) had recurring disease. The median number of resected ribs was 3. Sternal resection was performed in 6 cases (23%). Prosthetic thoracic reconstruction was deemed necessary in 24 cases (92%). Tumour recurrence was observed in 15 patients (58%). The median overall survival was 73.6 months. Primary and secondary tumours showed comparable survival (P = 0.49). At univariate analysis, disease recurrence and infiltrated margins on pathological specimens were associated with poorer survival (P = 0.014 and 0.022, respectively). In patients with primary sarcoma, the median progression-free survival was 13.3 months. Associated visceral resections were significantly associated to postoperative complications (P = 0.02). Conclusions: Chest wall resection followed by prosthetic reconstruction is feasible in carefully selected patients and should be performed by experienced surgeons with the aim of achieving free resection margins, resulting in improved long-term outcomes.
MeSH term(s)	Humans ; Neoplasm Recurrence, Local ; Retrospective Studies ; Sarcoma/surgery ; Thoracic Neoplasms/surgery ; Thoracic Wall/diagnostic imaging ; Thoracic Wall/surgery
Language	English
Publishing date	2021-02-03
Publishing country	England
Document type	Journal Article
ZDB-ID	2095298-3
ISSN	1569-9285 ; 1569-9293
ISSN (online)	1569-9285
ISSN	1569-9293
DOI	10.1093/icvts/ivab003
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Article ; Online: Immersive Three-dimensional Computed Tomography to Plan Chest Wall Resection for Lung Cancer.

Thumerel, Matthieu / Belaroussi, Yaniss / Prisciandaro, Elena / Chermat, Anaelle / Zarrouki, Sarah / Chevalier, Benjamin / Rodriguez, Arnaud / Hustache-Castaing, Romain / Jougon, Jacques

The Annals of thoracic surgery

2022 Volume 114, Issue 6, Page(s) 2379–2382

Abstract: Purpose: Chest wall resections for lung cancer treatment remain difficult to plan using standard 2-dimensional computed tomography. Although virtual reality headsets have been used in many medical contexts, they have not been used in chest wall ... ...

Abstract	Purpose: Chest wall resections for lung cancer treatment remain difficult to plan using standard 2-dimensional computed tomography. Although virtual reality headsets have been used in many medical contexts, they have not been used in chest wall resection planning. Description: We compared preoperative planning of a chest wall surgical resection for lung cancer treatment between senior and resident surgeons who used an immersive virtual reality device and a 2-dimensional computed tomography. Evaluation: Chest wall resection planning was more accurate when surgeons used virtual reality vs computed tomography analysis (28.6% vs 18.3%, P = .018), and this was particularly true in the resident surgeon group (27.4% vs 8.3%, P = .0025). Predictions regarding the need for chest wall substitutes were also more accurate when they were made using virtual reality vs computed tomography analysis in all groups (96% vs 68.5%, P < .0001). Other studied parameters were not affected by the use of the virtual reality tool. Conclusions: Virtual reality may offer enhanced accuracy for chest wall resection and reconstruction planning for lung cancer treatment.
MeSH term(s)	Humans ; Thoracic Wall/diagnostic imaging ; Thoracic Wall/surgery ; Tomography, X-Ray Computed/methods ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/surgery ; Thoracic Surgical Procedures/methods ; Thoracoplasty ; Imaging, Three-Dimensional
Language	English
Publishing date	2022-08-10
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	211007-6
ISSN	1552-6259 ; 0003-4975
ISSN (online)	1552-6259
ISSN	0003-4975
DOI	10.1016/j.athoracsur.2022.06.059
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Zs.A 252: Show issues

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Article ; Online: Patient risk factors for conversion during video-assisted thoracic surgery-the Epithor conversion score.

Fourdrain, Alex / Georges, Olivier / Gossot, Dominique / Falcoz, Pierre-Emmanuel / Jougon, Jacques / Baste, Jean-Marc / Marty-Ane, Charles-Henri / Berna, Pascal

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

2022 Volume 62, Issue 3

Abstract: Objectives: Intraoperative conversion from video-assisted thoracic surgery (VATS) to thoracotomy may occur during anatomical lung resection. The objectives of the present study were to identify risk factors for intraoperative conversion and to develop a ...

Abstract	Objectives: Intraoperative conversion from video-assisted thoracic surgery (VATS) to thoracotomy may occur during anatomical lung resection. The objectives of the present study were to identify risk factors for intraoperative conversion and to develop a predictive score. Methods: We performed a multicentre retrospective analysis of French thoracic surgery departments that contributed data on anatomical lung resections to the Epithor database over a 10-year period (from January-2010 to December-2019). Using univariate and multivariate logistic regression analyses, we determined risk factors for intraoperative conversion and elaborated the Epithor conversion score (ECS). The ECS was then validated in a cohort of patients operated on between January- and June-2020. Results: From January-2010 to December-2019, 210,037 patients had been registered in the Epithor database. Of these, 55,030 had undergone anatomical lung resection. We excluded patients who had upfront a thoracotomy or robotic-assisted thoracoscopic surgery (n = 40,293) and those with missing data (6,794). Hence, 7943 patients with intent-to-treat VATS were assessed: 7100 with a full VATS procedure and 843 patients with intraoperative conversion to thoracotomy (conversion rate: 10.6%). Thirteen potential risk factors were identified among patients' preoperative characteristics and planned surgical procedures and were weighted accordingly to give the ECS. The score showed acceptable discriminatory power (area under the curve: 0.62 in the development cohort and 0.64 in the validation cohort) and good calibration (P = 0.23 in the development cohort and 0.30 in the validation cohort). Conclusions: Thirteen potential preoperative risk factors were identified, enabling us to develop and validate the ECS-an easy-to-use, reproducible tool for estimating the risk of intraoperative conversion during VATS.
MeSH term(s)	Humans ; Lung Neoplasms/etiology ; Lung Neoplasms/surgery ; Pneumonectomy/adverse effects ; Pneumonectomy/methods ; Retrospective Studies ; Risk Factors ; Thoracic Surgery, Video-Assisted/adverse effects ; Thoracic Surgery, Video-Assisted/methods ; Thoracotomy/adverse effects ; Thoracotomy/methods ; Treatment Outcome
Language	English
Publishing date	2022-04-04
Publishing country	Germany
Document type	Journal Article
ZDB-ID	639293-3
ISSN	1873-734X ; 1010-7940 ; 1567-4258
ISSN (online)	1873-734X
ISSN	1010-7940 ; 1567-4258
DOI	10.1093/ejcts/ezac249
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Article: Une tumeur pulmonaire rare.

Bercovici, Déborah / Pierry, Clémence / Jougon, Jacques / Bégueret, Hugues

Annales de pathologie

2017 Volume 37, Issue 5, Page(s) 434–436

Title translation	A rare pulmonary tumor.
MeSH term(s)	Choristoma/pathology ; Female ; Humans ; Lung Diseases/pathology ; Lung Neoplasms/diagnosis ; Lung Neoplasms/pathology ; Meninges ; Meningioma/diagnosis ; Meningioma/pathology ; Middle Aged ; Organ Specificity ; Solitary Pulmonary Nodule/pathology
Language	French
Publishing date	2017-09-28
Publishing country	France
Document type	Case Reports ; Journal Article
ZDB-ID	225720-8
ISSN	0242-6498
ISSN	0242-6498
DOI	10.1016/j.annpat.2017.08.005
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Article ; Online: Cumulated Activity Comparison of

Laffon, Eric / Thumerel, Matthieu / Jougon, Jacques / Marthan, Roger

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

2017 Volume 58, Issue 6, Page(s) 888–890

Abstract: This work aimed at estimating the kinetic parameters, and hence cumulated activity ( ... ...

Abstract	This work aimed at estimating the kinetic parameters, and hence cumulated activity (A
MeSH term(s)	Animals ; Antibodies, Monoclonal/pharmacokinetics ; Carcinoma, Squamous Cell/diagnostic imaging ; Carcinoma, Squamous Cell/metabolism ; Carcinoma, Squamous Cell/pathology ; Cell Line, Tumor ; Computer Simulation ; Copper Radioisotopes/pharmacokinetics ; ErbB Receptors/metabolism ; Esophageal Neoplasms/diagnostic imaging ; Esophageal Neoplasms/metabolism ; Esophageal Neoplasms/pathology ; Lutetium/pharmacokinetics ; Metabolic Clearance Rate ; Mice ; Models, Biological ; Positron-Emission Tomography/methods ; Radiation Dosage ; Radioisotopes/pharmacokinetics ; Radiopharmaceuticals/pharmacokinetics ; Tissue Distribution
Chemical Substances	Antibodies, Monoclonal ; Copper Radioisotopes ; Radioisotopes ; Radiopharmaceuticals ; Lutetium (5H0DOZ21UJ) ; ErbB Receptors (EC 2.7.10.1)
Language	English
Publishing date	2017-01-12
Publishing country	United States
Document type	Comparative Study ; Journal Article
ZDB-ID	80272-4
ISSN	1535-5667 ; 0097-9058 ; 0161-5505 ; 0022-3123
ISSN (online)	1535-5667
ISSN	0097-9058 ; 0161-5505 ; 0022-3123
DOI	10.2967/jnumed.116.180521
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Zs.MO 328: Show issues

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Article: Impact of surgical approach on 90-day mortality after lung resection for nonsmall cell lung cancer in high-risk operable patients.

Etienne, Harry / Pagès, Pierre-Benoît / Iquille, Jules / Falcoz, Pierre Emmanuel / Brouchet, Laurent / Berthet, Jean-Philippe / Le Pimpec Barthes, Françoise / Jougon, Jacques / Filaire, Marc / Baste, Jean-Marc / Anne, Valentine / Renaud, Stéphane / D'Annoville, Thomas / Meunier, Jean Pierre / Jayle, Christophe / Dromer, Christian / Seguin-Givelet, Agathe / Legras, Antoine / Rinieri, Philippe /

Jaillard-Thery, Sophie / Margot, Vincent / Thomas, Pascal-Alexandre / Dahan, Marcel / Mordant, Pierre

ERJ open research

2024 Volume 10, Issue 1

Abstract: Introduction: Non-small cell lung cancer (NSCLC) is often associated with compromised lung function. Real-world data on the impact of surgical approach in NSCLC patients with compromised lung function are still lacking. The objective of this study is to ...

Abstract	Introduction: Non-small cell lung cancer (NSCLC) is often associated with compromised lung function. Real-world data on the impact of surgical approach in NSCLC patients with compromised lung function are still lacking. The objective of this study is to assess the potential impact of minimally invasive surgery (MIS) on 90-day post-operative mortality after anatomic lung resection in high-risk operable NSCLC patients. Methods: We conducted a retrospective multicentre study including all patients who underwent anatomic lung resection between January 2010 and October 2021 and registered in the Epithor database. High-risk patients were defined as those with a forced expiratory volume in 1 s (FEV Results: Of the 46 909 patients who met the inclusion criteria, 42 214 patients (90%) with both preoperative FEV Conclusion: By examining the impact of surgical approaches on 90-day mortality using a nationwide database, we found that either preoperative FEV
Language	English
Publishing date	2024-01-22
Publishing country	England
Document type	Journal Article
ZDB-ID	2827830-6
ISSN	2312-0541
ISSN	2312-0541
DOI	10.1183/23120541.00653-2023
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