Article ; Online: A
2020 Volume 10, Issue 1, Page(s) 17195
Abstract: Understanding the energetic state of the heart is essential for unraveling the central tenets of cardiac physiology. The heart uses a tremendous amount of energy and reductions in that energy supply can have lethal consequences. While ischemic events ... ...
Abstract | Understanding the energetic state of the heart is essential for unraveling the central tenets of cardiac physiology. The heart uses a tremendous amount of energy and reductions in that energy supply can have lethal consequences. While ischemic events clearly result in significant metabolic perturbations, heart failure with both preserved and reduced ejection fraction display reductions in energetic status. To date, most cardiac energetics have been performed using |
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MeSH term(s) | Animals ; Energy Metabolism/physiology ; Heart/physiology ; Heart Failure/metabolism ; Heart Failure/physiopathology ; Male ; Mice ; Mice, Inbred C57BL ; Myocardial Contraction/physiology ; Myocardium/metabolism ; N-Glycosyl Hydrolases/metabolism ; Proton Magnetic Resonance Spectroscopy/methods |
Chemical Substances | N-Glycosyl Hydrolases (EC 3.2.2.-) ; adenosine nucleosidase (EC 3.2.2.7) |
Language | English |
Publishing date | 2020-10-14 |
Publishing country | England |
Document type | Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't |
ZDB-ID | 2615211-3 |
ISSN | 2045-2322 ; 2045-2322 |
ISSN (online) | 2045-2322 |
ISSN | 2045-2322 |
DOI | 10.1038/s41598-020-74241-3 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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