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  1. Article ; Online: Systemic retinal biomarkers.

    Ranchod, Tushar M

    Current opinion in ophthalmology

    2021  Volume 32, Issue 5, Page(s) 439–444

    Abstract: Purpose of review: Systemic retinal biomarkers are biomarkers identified in the retina and related to evaluation and management of systemic disease. This review summarizes the background, categories and key findings from this body of research as well as ...

    Abstract Purpose of review: Systemic retinal biomarkers are biomarkers identified in the retina and related to evaluation and management of systemic disease. This review summarizes the background, categories and key findings from this body of research as well as potential applications to clinical care.
    Recent findings: Potential systemic retinal biomarkers for cardiovascular disease, kidney disease and neurodegenerative disease were identified using regression analysis as well as more sophisticated image processing techniques. Deep learning techniques were used in a number of studies predicting diseases including anaemia and chronic kidney disease. A virtual coronary artery calcium score performed well against other competing traditional models of event prediction.
    Summary: Systemic retinal biomarker research has progressed rapidly using regression studies with clearly identified biomarkers such as retinal microvascular patterns, as well as using deep learning models. Future systemic retinal biomarker research may be able to boost performance using larger data sets, the addition of meta-data and higher resolution image inputs.
    MeSH term(s) Anemia/diagnosis ; Anemia/diagnostic imaging ; Biomarkers ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/diagnostic imaging ; Humans ; Image Processing, Computer-Assisted ; Kidney Diseases/diagnosis ; Kidney Diseases/diagnostic imaging ; Neurodegenerative Diseases/diagnosis ; Neurodegenerative Diseases/diagnostic imaging ; Retina/diagnostic imaging
    Chemical Substances Biomarkers
    Language English
    Publishing date 2021-07-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1049383-9
    ISSN 1531-7021 ; 1040-8738
    ISSN (online) 1531-7021
    ISSN 1040-8738
    DOI 10.1097/ICU.0000000000000784
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3047: Show issues Location:
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  2. Article ; Online: Behavioral Economics and Risk Aversion as Potential Impediments to Delivering High-Quality Retinal Care.

    Ranchod, Tushar M / Jones, Chris A

    Retina (Philadelphia, Pa.)

    2016  Volume 36, Issue 12, Page(s) 2247–2249

    MeSH term(s) Economics, Behavioral ; Humans ; Ophthalmology/economics ; Retinal Diseases/therapy
    Language English
    Publishing date 2016-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603192-4
    ISSN 1539-2864 ; 0275-004X
    ISSN (online) 1539-2864
    ISSN 0275-004X
    DOI 10.1097/IAE.0000000000001378
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Tips and tricks in pediatric vitreoretinal surgery.

    Ranchod, Tushar M / Capone, Antonio

    International ophthalmology clinics

    2011  Volume 51, Issue 1, Page(s) 173–183

    MeSH term(s) Child ; Humans ; Retinal Diseases/surgery ; Treatment Outcome ; Vitreoretinal Surgery/methods
    Language English
    Publishing date 2011
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 207382-1
    ISSN 1536-9617 ; 0020-8167
    ISSN (online) 1536-9617
    ISSN 0020-8167
    DOI 10.1097/IIO.0b013e3182009b73
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  4. Article ; Online: Regression of retinal neovascularization after laser photocoagulation in incontinentia pigmenti.

    Ranchod, Tushar M / Trese, Michael T

    Retina (Philadelphia, Pa.)

    2010  Volume 30, Issue 4, Page(s) 708–709

    MeSH term(s) Child, Preschool ; Female ; Humans ; Incontinentia Pigmenti/surgery ; Laser Coagulation/adverse effects ; Neovascularization, Pathologic/etiology ; Retinal Diseases/etiology
    Language English
    Publishing date 2010-04
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 603192-4
    ISSN 1539-2864 ; 0275-004X
    ISSN (online) 1539-2864
    ISSN 0275-004X
    DOI 10.1097/IAE.0b013e3181cd4942
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Central retinal artery occlusion associated with hypertriglyceridemia.

    Ranchod, Tushar M / Ruby, Alan J

    Retinal cases & brief reports

    2010  Volume 4, Issue 4, Page(s) 368–369

    Abstract: Purpose: To report a case of central retinal artery occlusion associated with hypertriglyceridemia.: Methods: A 46-year-old man presented with decreased vision and was found to have a central retinal artery occlusion. Laboratory testing demonstrated ... ...

    Abstract Purpose: To report a case of central retinal artery occlusion associated with hypertriglyceridemia.
    Methods: A 46-year-old man presented with decreased vision and was found to have a central retinal artery occlusion. Laboratory testing demonstrated markedly elevated trig-lycerides with no other abnormalities. Tests for cardiac and carotid embolic sources and hypercoagulability were negative.
    Results: Dietary management and medication compliance resulted in dramatically decreased serum triglyceride levels. Vision remained poor during follow-up.
    Conclusion: Central retinal artery occlusion requires a medical evaluation for embolic and thrombotic sources. A fasting lipid panel is inexpensive to obtain and should be considered in the workup for central retinal artery occlusion.
    Language English
    Publishing date 2010
    Publishing country United States
    Document type Journal Article
    ISSN 1935-1089
    ISSN 1935-1089
    DOI 10.1097/ICB.0b013e3181b5ef82
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  6. Article ; Online: Primary treatment of diabetic macular edema.

    Ranchod, Tushar M / Fine, Stuart L

    Clinical interventions in aging

    2009  Volume 4, Page(s) 101–107

    Abstract: Diabetic macular edema (DME) is a leading cause of vision loss in older Americans. Thermal laser treatment remains the mainstay of treatment for DME. Recently, alternative primary treatments for DME have been evaluated. These treatments include ... ...

    Abstract Diabetic macular edema (DME) is a leading cause of vision loss in older Americans. Thermal laser treatment remains the mainstay of treatment for DME. Recently, alternative primary treatments for DME have been evaluated. These treatments include intravitreal injections of steroids as well as pharmaceuticals containing antibodies against vascular endothelial growth factor (VEGF). Surgical treatment has been shown to be appropriate in selected cases. We review the evidence and scientific rationale for various primary treatment options in patients with DME. Regular and timely ophthalmologic evaluation remains crucial to recognition and treatment of macular edema in diabetic patients.
    MeSH term(s) Diabetes Complications ; Humans ; Macular Edema/drug therapy ; Macular Edema/etiology ; Macular Edema/surgery ; Steroids/therapeutic use
    Chemical Substances Steroids
    Language English
    Publishing date 2009-05-14
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2364924-0
    ISSN 1178-1998 ; 1176-9092
    ISSN (online) 1178-1998
    ISSN 1176-9092
    DOI 10.2147/cia.s4357
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Peripapillary choroidal neovascularization in congenital retinoschisis.

    Ranchod, Tushar M / Faia, Lisa J / Drenser, Kimberly A

    Retinal cases & brief reports

    2011  Volume 5, Issue 4, Page(s) 336–338

    Abstract: Purpose: To report a case of peripapillary choroidal neovascularization (CNV) associated with congenital retinoschisis.: Methods: Case report.: Results: A 5-year-old white boy presented with regressed peripapillary CNV in the right eye along with ... ...

    Abstract Purpose: To report a case of peripapillary choroidal neovascularization (CNV) associated with congenital retinoschisis.
    Methods: Case report.
    Results: A 5-year-old white boy presented with regressed peripapillary CNV in the right eye along with peripheral retinoschisis in the same eye. The left eye presented with macular, lamellar, and peripheral retinoschisis changes. Optical coherence tomography and fluorescein angiography confirmed the presence of regressed peripapillary CNV in the right eye and also revealed retinal nonperfusion within the peripheral retinoschisis cavity in the right eye.
    Conclusion: The authors report a case of peripapillary CNV associated with congenital retinoschisis. The authors hypothesize that peripheral retinal nonperfusion in the right eye may have contributed to the development of CNV in that eye.
    Language English
    Publishing date 2011
    Publishing country United States
    Document type Journal Article
    ISSN 1935-1089
    ISSN 1935-1089
    DOI 10.1097/ICB.0b013e3181ff0960
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  8. Article: Retinal neovascularization after internal carotid artery occlusion.

    Ranchod, Tushar M / Drenser, Kimberley A / Garretson, Bruce R

    Retinal cases & brief reports

    2011  Volume 5, Issue 3, Page(s) 206–208

    Abstract: Purpose: To report a case of retinal neovascularization after surgical ligation of the internal carotid artery for treatment of direct carotid-cavernous fistula.: Methods: Case report.: Result: A 44-year-old Asian woman presented with unilateral ... ...

    Abstract Purpose: To report a case of retinal neovascularization after surgical ligation of the internal carotid artery for treatment of direct carotid-cavernous fistula.
    Methods: Case report.
    Result: A 44-year-old Asian woman presented with unilateral retinal neovascularization and vitreous hemorrhage. Surgical ligation of the ipsilateral internal carotid artery had been performed 14 years earlier as a treatment for carotid-cavernous fistula after failed attempts at fistula embolization. Vitrectomy was performed for removal of nonclearing vitreous hemorrhage, with intraoperative peripheral retinal ablation and cryotherapy of the lesion.
    Conclusion: We report a case of retinal neovascularization associated with total occlusion of the ipsilateral internal carotid artery 14 years earlier.
    Language English
    Publishing date 2011
    Publishing country United States
    Document type Journal Article
    ISSN 1935-1089
    ISSN 1935-1089
    DOI 10.1097/ICB.0b013e3181e1805a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Pharmacologic vitreodynamics.

    Ranchod, Tushar M / Goldenberg, David T / Trese, Michael T

    International ophthalmology clinics

    2009  Volume 49, Issue 2, Page(s) 135–140

    MeSH term(s) Animals ; Diabetic Retinopathy/drug therapy ; Diabetic Retinopathy/metabolism ; Diabetic Retinopathy/surgery ; Humans ; Hyaluronoglucosaminidase/pharmacokinetics ; Hyaluronoglucosaminidase/therapeutic use ; Soy Foods ; Subtilisins/pharmacokinetics ; Subtilisins/therapeutic use ; Treatment Outcome ; Vitrectomy ; Vitreous Body/metabolism ; Vitreous Body/pathology ; Vitreous Hemorrhage/drug therapy ; Vitreous Hemorrhage/metabolism ; Vitreous Hemorrhage/surgery
    Chemical Substances Hyaluronoglucosaminidase (EC 3.2.1.35) ; Subtilisins (EC 3.4.21.-) ; nattokinase (H81695M5OP)
    Language English
    Publishing date 2009
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 207382-1
    ISSN 1536-9617 ; 0020-8167
    ISSN (online) 1536-9617
    ISSN 0020-8167
    DOI 10.1097/IIO.0b013e31819fd66b
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  10. Article ; Online: Pandemic 2009 influenza A H1N1 retinopathy.

    Faridi, Omar S / Ranchod, Tushar M / Ho, Lawrence Y / Ruby, Alan J

    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie

    2010  Volume 45, Issue 3, Page(s) 286–287

    MeSH term(s) Canada/epidemiology ; Disease Outbreaks ; Eye Infections, Viral/diagnosis ; Eye Infections, Viral/epidemiology ; Eye Infections, Viral/virology ; Female ; Fluorescein Angiography ; Humans ; Influenza A Virus, H1N1 Subtype ; Influenza, Human/diagnosis ; Influenza, Human/epidemiology ; Influenza, Human/virology ; Retinal Diseases/diagnosis ; Retinal Diseases/epidemiology ; Retinal Diseases/virology ; Visual Acuity ; Young Adult
    Language English
    Publishing date 2010-06
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 80091-0
    ISSN 1715-3360 ; 0008-4182
    ISSN (online) 1715-3360
    ISSN 0008-4182
    DOI 10.3129/i10-030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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