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Article ; Online: Breastfeeding practices in neonatal wards in Spain. Neo-BFHI international survey.

Cabrera-Lafuente, Marta / Alonso-Díaz, Clara / Pumarega, Maria Teresa Moral / Díaz-Almirón, Mariana / Haiek, Laura N / Maastrup, Ragnhild / Pallás-Alonso, Carmen

Anales de pediatria

2022 Volume 96, Issue 4, Page(s) 300–308

Abstract: Introduction: In 2017, a worldwide survey was conducted on compliance with the practices promoted by Neo-BFHI (Baby-friendly Hospital Initiative expansion to neonatal wards).: Objective: To present the results of the Spanish wards that participated ... ...

Abstract	Introduction: In 2017, a worldwide survey was conducted on compliance with the practices promoted by Neo-BFHI (Baby-friendly Hospital Initiative expansion to neonatal wards). Objective: To present the results of the Spanish wards that participated in the global survey and compare them with those obtained internationally. Material and methods: Cross-sectional study through a survey on compliance with the Neo-BFHI ("Three basic principles", "Ten steps adapted to neonatal wards" and "the compliance with the International Code of Marketing of Breast-milk Substitutes" and subsequent relevant World Health Assembly resolutions). Compliance was calculated as the mean in each indicator and a final mean score for each neonatal unit. For the partial and final scores for each country and at the international level, the median was used. All scores ranged between 0 and 100. Results: The response rate in Spain was 90%. The range of the national mean for neonatal wards were from 37 to 99, with no differences in the final score according to the level of care. The global score for Spain (72) is below the international median (77) and this also occurs in 8 of 14 items. The neonatal wards from BFHI designated hospitals, obtained a significantly higher mean global score, and in 9 of 14 items than the non-accredited ones. Conclusions: Both international and national results indicate an improvement in breast feeding practices in neonatal units. The benefits of the BFHI accreditation of maternity reach neonatal wards. Spain has several key points below the international score.
MeSH term(s)	Breast Feeding/statistics & numerical data ; Cross-Sectional Studies ; Female ; Health Promotion/methods ; Hospitals ; Humans ; Infant, Newborn ; Nurseries, Hospital ; Pregnancy ; Spain
Language	English
Publishing date	2022-05-03
Publishing country	Spain
Document type	Journal Article
ZDB-ID	2830901-7
ISSN	2341-2879 ; 2341-2879
ISSN (online)	2341-2879
ISSN	2341-2879
DOI	10.1016/j.anpede.2021.04.010
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Prácticas de lactancia materna en las unidades neonatales de España. Encuesta internacional Neo-IHAN.

Cabrera-Lafuente, Marta / Alonso-Díaz, Clara / Moral Pumarega, Maria Teresa / Díaz-Almirón, Mariana / Haiek, Laura N / Maastrup, Ragnhild / Pallás-Alonso, Carmen

Anales de pediatria

2021

Abstract: Introduction: In 2017, a worldwide survey was conducted on compliance with the practices promoted by Neo-BFHI (Baby-friendly Hospital Initiative expansion to neonatal wards).: Objective: Present the results of the Spanish wards that participated in ... ...

Title translation	Breastfeeding practices in neonatal wards in Spain. Neo-BFHI international survey.
Abstract	Introduction: In 2017, a worldwide survey was conducted on compliance with the practices promoted by Neo-BFHI (Baby-friendly Hospital Initiative expansion to neonatal wards). Objective: Present the results of the Spanish wards that participated in the global survey and compare them with those obtained internationally. Material and methods: Cross-sectional study through a survey on compliance with the Neo-BFHI ("Three basic principles", "Ten steps adapted to neonatal wards" and "the compliance with the International Code of Marketing of Breast-milk Substitutes" and subsequent relevant World Health Assembly resolutions). Compliance was calculated as the mean in each indicator and a final mean score for each neonatal unit. For the partial and final scores for each country and at the international level, the median was used. All score ranged between 0 and 100. Results: The response rate in Spain was 90%. The range of the national mean for neonatal wards were from 37 to 99, with no differences in the final score according to the level of care. The global score for Spain (72) is below the international median (77) and this also occurs in 8 of 14 items. The neonatal wards from BFHI designated hospitals, obtained a significantly higher mean global score, and in 9 of 14 items than the non-accredited ones. Conclusions: Both international and national results indicate an improvement in breastfeeding practices in neonatal units. The benefits of the BFHI accreditation of maternity reach neonatal wards. Spain has several key points below the international score.
Language	Spanish
Publishing date	2021-05-24
Publishing country	Spain
Document type	English Abstract ; Journal Article
ZDB-ID	2830901-7
ISSN	2341-2879 ; 2341-2879
ISSN (online)	2341-2879
ISSN	2341-2879
DOI	10.1016/j.anpedi.2021.04.010
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Article ; Online: First case of neonatal infection due to COVID-19 in Spain.

Alonso Díaz, Clara / López Maestro, María / Moral Pumarega, María Teresa / Flores Antón, Beatriz / Pallás Alonso, Carmen

Anales de pediatria

2020 Volume 92, Issue 4, Page(s) 237–238

Keywords	covid19
Language	English
Publishing date	2020-04-01
Publishing country	Netherlands
Document type	Case Reports
ZDB-ID	2830901-7
ISSN	2341-2879 ; 2341-2879
ISSN (online)	2341-2879
ISSN	2341-2879
DOI	10.1016/j.anpede.2020.03.002
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Article ; Online: Clinical Impact of Supplementation with Pasteurized Donor Human Milk by High-Temperature Short-Time Method versus Holder Method in Extremely Low Birth Weight Infants: A Multicentre Randomized Controlled Trial.

García-Lara, Nadia Raquel / Escuder-Vieco, Diana / Cabrera-Lafuente, Marta / Keller, Kristin / De Diego-Poncela, Cristina / Jiménez-González, Concepción / Núñez-Ramos, Raquel / Flores-Antón, Beatriz / Escribano-Palomino, Esperanza / Alonso-Díaz, Clara / Vázquez-Román, Sara / Ureta-Velasco, Noelia / Cruz-Bértolo, Javier De La / Pallás-Alonso, Carmen Rosa

Nutrients

2024 Volume 16, Issue 7

Abstract: Nosocomial infections are a frequent and serious problem in extremely low birth weight (ELBW) infants. Donor human milk (DHM) is the best alternative for feeding these babies when mother's own milk (MOM) is not available. Recently, a patented prototype ... ...

Abstract	Nosocomial infections are a frequent and serious problem in extremely low birth weight (ELBW) infants. Donor human milk (DHM) is the best alternative for feeding these babies when mother's own milk (MOM) is not available. Recently, a patented prototype of a High-Temperature Short-Time (HTST) pasteurizer adapted to a human milk bank setting showed a lesser impact on immunologic components. We designed a multicentre randomized controlled trial that investigates whether, in ELBW infants with an insufficient MOM supply, the administration of HTST pasteurized DHM reduces the incidence of confirmed catheter-associated sepsis compared to DHM pasteurized with the Holder method. From birth until 34 weeks postmenstrual age, patients included in the study received DHM, as a supplement, pasteurized by the Holder or HTST method. A total of 213 patients were randomized; 79 (HTST group) and 81 (Holder group) were included in the analysis. We found no difference in the frequency of nosocomial sepsis between the patients of the two methods-41.8% (33/79) of HTST group patients versus 45.7% (37/81) of Holder group patients, relative risk 0.91 (0.64-1.3),
MeSH term(s)	Infant ; Infant, Newborn ; Humans ; Infant, Extremely Low Birth Weight ; Milk, Human ; Temperature ; Dietary Supplements ; Sepsis/epidemiology ; Sepsis/prevention & control
Language	English
Publishing date	2024-04-08
Publishing country	Switzerland
Document type	Randomized Controlled Trial ; Multicenter Study ; Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu16071090
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Article ; Online: Primer caso de infección neonatal por SARS-CoV-2 en España.

Alonso Díaz, Clara / López Maestro, María / Moral Pumarega, María Teresa / Flores Antón, Beatriz / Pallás Alonso, Carmen Rosa

Anales de pediatria

2020 Volume 92, Issue 4, Page(s) 237–238

Title translation	First case of neonatal infection due to SARS-CoV-2 in Spain.
MeSH term(s)	Adult ; Asymptomatic Diseases ; Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; Disease Transmission, Infectious ; Female ; Humans ; Infant, Low Birth Weight ; Infant, Newborn ; Infant, Newborn, Diseases/diagnosis ; Pandemics ; Pneumonia, Viral/diagnosis ; SARS-CoV-2 ; Spain
Keywords	covid19
Language	Spanish
Publishing date	2020-03-31
Publishing country	Netherlands
Document type	Case Reports
ZDB-ID	2830901-7
ISSN	2341-2879 ; 2341-2879
ISSN (online)	2341-2879
ISSN	2341-2879
DOI	10.1016/j.anpedi.2020.03.002
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Article: First case of neonatal infection due to COVID 19 in Spain

Díaz, Clara Alonso / Maestro, María López / Pumarega, María Teresa Moral / Antón, Beatriz Flores / Alonso, Carmen Pallás

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #27728
Database	COVID19

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Article ; Online: Cystic phenotype and chronic kidney disease in autosomal dominant Alport syndrome.

Bada-Bosch, Teresa / Sevillano, Angel M / Teresa Sánchez-Calvin, María / Palma-Milla, Carmen / Alba de Cáceres, Ignacio / Díaz-Crespo, Francisco / Trujillo, Hernando / Alonso, Marina / Cases-Corona, Clara / Shabaka, Amir / Quesada-Espinosa, Juan Francisco / Rosales, José Miguel Lezana / Gutiérrez, Eduardo / Fernández-Juárez, Gema / Caravaca-Fontán, Fernando / Praga, Manuel

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

2024

Abstract: Background and hypothesis: Autosomal Dominant Alport Syndrome (ADAS), also known as Thin Basement Membrane Disease (TBMD), is caused by pathogenic variants in COL4A3 and COL4A4 genes. A cystic phenotype has been described in some patients with TBMD, but ...

Abstract	Background and hypothesis: Autosomal Dominant Alport Syndrome (ADAS), also known as Thin Basement Membrane Disease (TBMD), is caused by pathogenic variants in COL4A3 and COL4A4 genes. A cystic phenotype has been described in some patients with TBMD, but no genetic studies were performed. We conducted a genetic and radiologic investigation in a cohort of ADAS patients to analyze the prevalence of multicystic kidney disease (MKD) and its association with Chronic Kidney Disease (CKD). Methods: Retrospective single-center cohort study. Thirty-one patients showing pathogenic or likely pathogenic variants in COL4A3 or COL4A4 from a cohort of 79 patients with persistent microscopic hematuria were included. Mean follow-up was 9.4±9.6 years. The primary objective of the study was to determine the prevalence of MKD in the cohort of ADAS patients. Secondary objectives were to determine risk factors associated with an eGFR<45 ml/min/1.73m2 at the time of genetic and radiologic evaluation and to investigate the coexistence of other genetic abnormalities associated with familial hematuria and cystic kidney disease. Results: MKD was found in 16 patients (52%). Mean number of cysts per kidney was 12.7±5.5. No genetic abnormalities were found in a panel of 101 other genes related to familial hematuria, focal segmental glomerulosclerosis and cystic kidney disease. A greater number of patients with MKD had an eGFR<45 ml/min/1.73m2 (63% vs 7%, p=0.006) and more advanced CKD than patients without MKD. The annual rate of eGFR decline was greater in patients with MKD: -1.8 vs 0.06 ml/min/1.73m2/year (p=0.009). By multivariable linear regression analysis, the main determinants of eGFR change per year were time-averaged proteinuria (p=0.002) and MKD (p=0.02). Conclusion: MKD is commonly found in ADAS and is associated with a worse kidney outcome. No pathogenic variants were found in genes other than COL4A3/COL4A4.
Language	English
Publishing date	2024-01-04
Publishing country	England
Document type	Journal Article
ZDB-ID	90594-x
ISSN	1460-2385 ; 0931-0509
ISSN (online)	1460-2385
ISSN	0931-0509
DOI	10.1093/ndt/gfae002
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Zs.A 2198: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Immunometabolic Profile Associated with Progressive Damage of the Intestinal Mucosa in Adults Screened for Colorectal Cancer: Association with Diet.

González, Celestino / Ruiz-Saavedra, Sergio / Gómez-Martín, María / Zapico, Aida / López-Suarez, Patricia / Suárez, Ana / Suárez González, Adolfo / Del Rey, Carmen González / Díaz, Elena / Alonso, Ana / de Los Reyes-Gavilán, Clara G / González, Sonia

International journal of molecular sciences

2023 Volume 24, Issue 22

Abstract: Environmental factors such as diet and lifestyle have been shown to influence the development of some intestinal mucosal lesions that may be precursors of colorectal cancer (CRC). The presence of these alterations seems to be associated with misbalanced ... ...

Abstract	Environmental factors such as diet and lifestyle have been shown to influence the development of some intestinal mucosal lesions that may be precursors of colorectal cancer (CRC). The presence of these alterations seems to be associated with misbalanced immunological parameter levels. However, it is still unclear as to which immunological parameters are altered in each phase of CRC development. In this work, we aimed to study the potential relationships of immunological and metabolic parameters with diet in a CRC-related lesion context. Dietary information was obtained using an annual semi-quantitative food-frequency questionnaire (FFQ) from 93 volunteers classified via colonoscopy examination according to the presence of intestinal polyps or adenocarcinoma. Cytokines, chemokines, and adipokines were determined from serum samples. We observed a reduction in adiponectin according to the damage to the mucosa, accompanied by an increase and decrease in C-X-C motif chemokine ligand 10 (CXCL10) and resistin, respectively, in CRC cases. The presence of aberrant crypt foci (ACF) in the polyp group was associated with higher tumor necrosis factor-alpha (TNF-α) concentrations. Vegetables were directly correlated with adiponectin and resistin levels, while the opposite occurred with red meat. A bioactive compound, soluble pectin, showed a negative association with TNF-α. Future dietary strategies could be developed to modulate specific immunological parameters in the context of CRC.
MeSH term(s)	Humans ; Adult ; Resistin ; Colorectal Neoplasms/metabolism ; Adiponectin ; Tumor Necrosis Factor-alpha ; Diet ; Intestinal Mucosa/metabolism
Chemical Substances	Resistin ; Adiponectin ; Tumor Necrosis Factor-alpha
Language	English
Publishing date	2023-11-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms242216451
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Article ; Online: Egocentric sexual network analysis among gay and bisexual men who have sex with men with and without mpox infection.

Sönmez, İbrahim / Martínez Riveros, Héctor / Folch, Cinta / Suñer, Clara / Díaz, Yesika / Alonso, Lucía / Agusti, Cristina / Mendoza, Adrià / Tarín-Vicente, Eloy José / Oller, Xènia / Alemany, Andrea / Rivero, Àngel / Orviz, Eva / Silva-Klug, Ana / Mitjà, Oriol / Casabona, Jordi

Sexually transmitted infections

2023 Volume 99, Issue 8, Page(s) 541–547

Abstract: Objectives: Recent outbreaks of the mpox (monkeypox) virus have been detected in dense sexual networks of gay and bisexual men who have sex with men (GBMSM). The objective of this study is to describe and compare the epidemiological and behavioural ... ...

Abstract	Objectives: Recent outbreaks of the mpox (monkeypox) virus have been detected in dense sexual networks of gay and bisexual men who have sex with men (GBMSM). The objective of this study is to describe and compare the epidemiological and behavioural characteristics, as well as the sexual networks, of GBMSM diagnosed with mild mpox in Spain. Methods: A prospective case-control study was conducted in Spain from July 2022 to February 2023. The study targeted a key population of GBMSM aged 18 years or older. Study participants were categorised into cases, those who were diagnosed with mpox virus infection; and controls, those who were not diagnosed. We examined and compared the sexual network characteristics of the two groups-mpox-positive (mpox-P) and mpox-negative (mpox-N) egos-using χ Results: Among the 105 participants, 35 (33.3%) were mpox-P. Compared with mpox-N, mpox-P respondents more frequently reported syphilis (mpox-P: 31.4%; mpox-N: 12.9%) and HIV (mpox-P: 45.7%; mpox-N: 18.6%), and mpox-P individuals to have had at least one sexual contact with a confirmed mpox case (mpox-P: 62.5%; mpox-N: 8.3%). In the egocentric network analysis, mpox-P respondents had a higher prevalence of group sex with alters (mpox-P: 18.5%; mpox-N: 8.9%) and one-time sexual partners (mpox-P: 46.1%; mpox-N: 31.7%). Multivariable logistic regressions showed that reporting stranger/client ties (adjusted OR (aOR)=10.3, 95% CI 1.39 to 76.6) with alters, being vaccinated for mpox (aOR=0.07, 95% CI 0.02 to 0.24) and tie strength heterogeneity (aOR=0.01, 95% CI 0.00 to 0.42) were associated with mpox infection. Conclusions: Our findings highlight the role of demographic, epidemiological and sexual network characteristics in the transmission of mpox virus during the outbreak in Spain. These findings have important implications for future prevention efforts.
MeSH term(s)	Male ; Humans ; Sexual and Gender Minorities ; Homosexuality, Male ; Case-Control Studies ; Mpox (monkeypox) ; HIV Infections/prevention & control ; HIV Seropositivity
Language	English
Publishing date	2023-09-13
Publishing country	England
Document type	Journal Article
ZDB-ID	1420303-0
ISSN	1472-3263 ; 1368-4973
ISSN (online)	1472-3263
ISSN	1368-4973
DOI	10.1136/sextrans-2023-055901
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Article: [First case of neonatal infection due to SARS-CoV-2 in Spain]

Alonso Diaz, Clara / Lopez Maestro, Maria / Moral Pumarega, Maria Teresa / Flores Anton, Beatriz / Pallas Alonso, Carmen

An Pediatr (Barc)

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #34559
Database	COVID19

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