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  1. Article: Prise en charge nutritionnelle des patients de réanimation ayant une infection au SARS-CoV-2.

    Pardo, Emmanuel

    Le praticien en anesthesie reanimation

    2020  Volume 24, Issue 4, Page(s) 218–224

    Abstract: Patients with severe cases of COVID-19 are at high nutritional risk during their ICU stay. Prolonged immobilization associated with an exacerbated systemic inflammatory response is a major provider of ICU-acquired muscle weakness. Early enteral nutrition ...

    Title translation Nutritional support for critically ill patients suffering from SARS-CoV-2 infection.
    Abstract Patients with severe cases of COVID-19 are at high nutritional risk during their ICU stay. Prolonged immobilization associated with an exacerbated systemic inflammatory response is a major provider of ICU-acquired muscle weakness. Early enteral nutrition is recommended to gradually reach the energy target of 25 kcal/kg/day and protein target of 1.3 g/kg/day around D4. The occurrence of a Refeeding syndrome should be closely monitored. In case of feeding intolerance refractory to a prokinetic treatment, complementary or total parenteral nutrition is advised, favouring new generation mixed lipid emulsions (containing fish oil) and regular monitoring of triglyceridemia. Nutrition care of critically ill patients should be carried out with limited procedures that may pose a risk of contamination for the healthcare staff.
    Keywords covid19
    Language French
    Publishing date 2020-07-10
    Publishing country France
    Document type English Abstract ; Journal Article ; Review
    ISSN 1279-7960
    ISSN 1279-7960
    DOI 10.1016/j.pratan.2020.07.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Prise en charge nutritionnelle des patients de réanimation ayant une infection au SARS-CoV-2

    Pardo, Emmanuel

    Le Praticien en Anesthésie Réanimation

    2020  Volume 24, Issue 4, Page(s) 218–224

    Keywords Anesthesiology and Pain Medicine ; Emergency ; Emergency Medicine ; covid19
    Language French
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 1279-7960
    DOI 10.1016/j.pratan.2020.07.002
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Response to "Gastric ultrasound, citrulline, and intestinal fatty acid-binding protein as markers of gastrointestinal dysfunction in critically ill patients: A pilot prospective cohort study".

    El Khoury, Daniel / Pardo, Emmanuel / Verdonk, Franck

    JPEN. Journal of parenteral and enteral nutrition

    2023  Volume 47, Issue 5, Page(s) 593–594

    MeSH term(s) Humans ; Citrulline ; Critical Illness/therapy ; Prospective Studies ; Gastrointestinal Diseases/diagnostic imaging ; Fatty Acid-Binding Proteins
    Chemical Substances Citrulline (29VT07BGDA) ; Fatty Acid-Binding Proteins
    Language English
    Publishing date 2023-05-30
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 800861-9
    ISSN 1941-2444 ; 0148-6071
    ISSN (online) 1941-2444
    ISSN 0148-6071
    DOI 10.1002/jpen.2514
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1524: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Prise en charge nutritionnelle des patients de réanimation ayant une infection au SARS-CoV-2./ [Nutritional support for critically ill patients suffering from SARS-CoV-2 infection]

    Pardo, Emmanuel

    Le Praticien en anesthesie reanimation

    Abstract: Patients with severe cases of COVID-19 are at high nutritional risk during their ICU stay. Prolonged immobilization associated with an exacerbated systemic inflammatory response is a major provider of ICU-acquired muscle weakness. Early enteral nutrition ...

    Abstract Patients with severe cases of COVID-19 are at high nutritional risk during their ICU stay. Prolonged immobilization associated with an exacerbated systemic inflammatory response is a major provider of ICU-acquired muscle weakness. Early enteral nutrition is recommended to gradually reach the energy target of 25 kcal/kg/day and protein target of 1.3 g/kg/day around D4. The occurrence of a Refeeding syndrome should be closely monitored. In case of feeding intolerance refractory to a prokinetic treatment, complementary or total parenteral nutrition is advised, favouring new generation mixed lipid emulsions (containing fish oil) and regular monitoring of triglyceridemia. Nutrition care of critically ill patients should be carried out with limited procedures that may pose a risk of contamination for the healthcare staff.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #723062
    Database COVID19

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  5. Article ; Online: Cancers œsophagiens : nouveautés et défis des prises en charge chirurgicales.

    Voron, Thibault / Julio, Camille / Pardo, Emmanuel

    Bulletin du cancer

    2022  Volume 110, Issue 5, Page(s) 533–539

    Abstract: Surgical resection of esophageal carcinoma is one of the mainstays of curative treatment for these cancers. During the last decade, numerous improvements in surgical approaches and perioperative management of these patients have resulted in a decrease in ...

    Title translation Esophageal carcinoma: novelties and challenges in surgery.
    Abstract Surgical resection of esophageal carcinoma is one of the mainstays of curative treatment for these cancers. During the last decade, numerous improvements in surgical approaches and perioperative management of these patients have resulted in a decrease in postoperative morbidity and mortality. Thus, centralization of patients with esophagogastric adenocarcinoma in high volume center, development of minimally invasive surgery and improvements in surgical imaging have led to reduce mortality rate, major pulmonary complication rate and postoperative chylothorax rate. Optimization of postoperative management with enhanced recovery programs has meanwhile reduced the rate of major postoperative complication and the hospital length of stay. The objective of this review is to give an overview of novelties and challenges regarding surgical management of patients with esophageal carcinoma.
    MeSH term(s) Humans ; Esophagectomy/adverse effects ; Esophagectomy/methods ; Length of Stay ; Carcinoma/surgery ; Esophageal Neoplasms/surgery ; Esophageal Neoplasms/pathology ; Adenocarcinoma/pathology ; Postoperative Complications/etiology ; Postoperative Complications/surgery ; Minimally Invasive Surgical Procedures/methods ; Treatment Outcome
    Language French
    Publishing date 2022-11-03
    Publishing country France
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 213270-9
    ISSN 1769-6917 ; 0007-4551
    ISSN (online) 1769-6917
    ISSN 0007-4551
    DOI 10.1016/j.bulcan.2022.09.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh III Zs.15: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Anesthesia for digestive tract endoscopy.

    Pardo, Emmanuel / Camus, Marine / Verdonk, Franck

    Current opinion in anaesthesiology

    2022  Volume 35, Issue 4, Page(s) 528–535

    Abstract: Purpose of review: Nonoperating room anesthesia for digestive tract endoscopy has its own specificities and requires practical training. Monitoring devices, anesthetic drugs, understanding of procedures and management of complications are critical ... ...

    Abstract Purpose of review: Nonoperating room anesthesia for digestive tract endoscopy has its own specificities and requires practical training. Monitoring devices, anesthetic drugs, understanding of procedures and management of complications are critical aspects.
    Recent findings: New data are available regarding risk factors for intra- and postoperative complications (based on anesthesia registries), airway management, new anesthetic drugs, techniques of administration and management of advances in interventional endoscopy procedures.
    Summary: Digestive tract endoscopy is a common procedure that takes place outside the operating room most of the time and has become more and more complex due to advanced invasive procedures. Prior evaluation of the patient's comorbidities and a good understanding of the objectives and constraints of the endoscopic procedures are required. Assessing the risk of gastric content aspiration is critical for determining appropriate anesthetic protocols. The availability of adequate monitoring (capnographs adapted to spontaneous ventilation, bispectral index), devices for administration of anesthetic/sedative agents (target-controlled infusion) and oxygenation (high flow nasal oxygenation) guarantees the quality of sedation and patient' safety during endoscopic procedures. Knowledge of the specificities of each interventional endoscopic procedure (endoscopic retrograde cholangiopancreatography, submucosal dissection) allows preventing complications during anesthesia.
    MeSH term(s) Anesthesia/adverse effects ; Anesthesia/methods ; Anesthesiology ; Anesthetics ; Endoscopy ; Endoscopy, Gastrointestinal/adverse effects ; Gastrointestinal Tract ; Humans
    Chemical Substances Anesthetics
    Language English
    Publishing date 2022-07-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 645203-6
    ISSN 1473-6500 ; 0952-7907
    ISSN (online) 1473-6500
    ISSN 0952-7907
    DOI 10.1097/ACO.0000000000001162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2564: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Dynamic assessment of prealbumin for nutrition support effectiveness in critically ill patients.

    Pardo, Emmanuel / Jabaudon, Matthieu / Godet, Thomas / Pereira, Bruno / Morand, Dominique / Futier, Emmanuel / Arpajou, Gauthier / Le Cam, Elena / Bonnet, Marie-Pierre / Constantin, Jean-Michel

    Clinical nutrition (Edinburgh, Scotland)

    2024  Volume 43, Issue 6, Page(s) 1343–1352

    Abstract: Background & aims: Serum prealbumin is considered to be a sensitive predictor of clinical outcomes and a quality marker for nutrition support. However, its susceptibility to inflammation restricts its usage in critically ill patients according to ... ...

    Abstract Background & aims: Serum prealbumin is considered to be a sensitive predictor of clinical outcomes and a quality marker for nutrition support. However, its susceptibility to inflammation restricts its usage in critically ill patients according to current guidelines. We assessed the performance of the initial value of prealbumin and dynamic changes for predicting the ICU mortality and the effectiveness of nutrition support in critically ill patients.
    Methods: This monocentric study included patients admitted to the ICU between 2009 and 2016, having at least one initial prealbumin value available. Prospectively recorded data were extracted from the electronic ICU charts. We used both univariable and multivariable logistic regressions to estimate the performance of prealbumin for the prediction of ICU mortality. Additionally, the association between prealbumin dynamic changes and nutrition support was assessed via a multivariable linear mixed-effects model and multivariable linear regression. Performing subgroup analysis assisted in identifying patients for whom prealbumin dynamic assessment holds specific relevance.
    Results: We included 3136 patients with a total of 4942 prealbumin levels available. Both prealbumin measured at ICU admission (adjusted odds-ratio (aOR) 0.04, confidence interval (CI) 95% 0.01-0.23) and its change over the first week (aOR 0.02, CI 95 0.00-0.19) were negatively associated with ICU mortality. Throughout the entire ICU stay, prealbumin dynamic changes were associated with both cumulative energy (estimate: 33.2, standard error (SE) 0.001, p < 0.01) and protein intakes (1.39, SE 0.001, p < 0.01). During the first week of stay, prealbumin change was independently associated with mean energy (6.03e-04, SE 2.32e-04, p < 0.01) and protein intakes (1.97e-02, SE 5.91e-03, p < 0.01). Notably, the association between prealbumin and energy intake was strongest among older or malnourished patients, those suffering from increased inflammation and those with high disease severity. Finally, prealbumin changes were associated with a positive mean nitrogen balance at day 7 only in patients with SOFA <4 (p = 0.047).
    Conclusion: Prealbumin measured at ICU admission and its change during the first-week serve as an accurate predictor of ICU mortality. Prealbumin dynamic assessment may be a reliable tool to estimate the effectiveness of nutrition support in the ICU, especially among high-risk patients.
    Language English
    Publishing date 2024-04-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 604812-2
    ISSN 1532-1983 ; 0261-5614
    ISSN (online) 1532-1983
    ISSN 0261-5614
    DOI 10.1016/j.clnu.2024.04.015
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1774: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Complications cardiaques de la COVID-19 en réanimation.

    Tran Van Nho, Jessica / Pardo, Emmanuel

    Le praticien en anesthesie reanimation

    2020  Volume 24, Issue 4, Page(s) 212–217

    Abstract: The World Health Organization declared the SARS-CoV-2 infection causing severe acute respiratory distress a global pandemic in March 2020. While respiratory features are commonly at the forefront of the disease, cardiovascular complications have been ... ...

    Title translation Cardiac complications in critically ill COVID-19 patients.
    Abstract The World Health Organization declared the SARS-CoV-2 infection causing severe acute respiratory distress a global pandemic in March 2020. While respiratory features are commonly at the forefront of the disease, cardiovascular complications have been observed and associated with a poorer prognosis. The ACE2 enzyme intrinsically involved in the physiology of cardiac function and in the development of hypertension and diabetes has been identified as a functional receptor for SARS-CoV-2. It is difficult to highlight the precise mechanisms of cardiac damage because of its possible multiple implications, through direct damage from SARS-CoV-2 responsible for viral myocarditis or indirect damage from the state of exacerbated systemic inflammation associated with hypoxaemia. The treatments of the disease may also induce adverse effects such as an increase in QT segment duration. Measurements of cardiac biomarkers are required if myocardial damage is suspected and are part of a panel of arguments confronted with clinical features, ultrasonic monitoring and electrocardiogram. As the cardiac disorders increase post-hospital morbidity, risk stratification with cardiac MRI and prolonged follow-up are required.
    Keywords covid19
    Language French
    Publishing date 2020-07-10
    Publishing country France
    Document type English Abstract ; Journal Article ; Review
    ISSN 1279-7960
    ISSN 1279-7960
    DOI 10.1016/j.pratan.2020.07.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Gastric Cross-Sectional Area to Predict Gastric Intolerance in Critically Ill Patients: The Sono-ICU Prospective Observational Bicenter Study.

    El Khoury, Daniel / Pardo, Emmanuel / Cambriel, Amelie / Bonnet, Francis / Pham, Tai / Cholley, Bernard / Quesnel, Christophe / Verdonk, Franck

    Critical care explorations

    2023  Volume 5, Issue 3, Page(s) e0882

    Abstract: To evaluate the correlation between gastric cross-sectional area (GCSA) and the occurrence of gastric intolerance in critically ill patients within 24 hours of the measurement.: Design: Two-center prospective observational study.: Setting: Two ... ...

    Abstract To evaluate the correlation between gastric cross-sectional area (GCSA) and the occurrence of gastric intolerance in critically ill patients within 24 hours of the measurement.
    Design: Two-center prospective observational study.
    Setting: Two academic ICUs in France between June 2020 and August 2021.
    Patients: All surgical intubated ICU patients greater than or equal to 18 years old receiving enteral feeding for greater than 12 hours.
    Interventions: None.
    Measurements and main results: Forty-four patients were included, 11 (25%) of whom presented digestive intolerance. Primary outcome was assessment of the association between GCSA and the occurrence of gastric intolerance within 24 hours of the measurement. GCSA value was significantly higher in patients with upper digestive intolerance compared to those without (553 mm
    Conclusions: Measurement of GCSA by ultrasound would allow prediction of gastric intolerance in critically ill patients. This should be confirmed by a prospective score validation and interventional trials.
    Language English
    Publishing date 2023-03-20
    Publishing country United States
    Document type Journal Article
    ISSN 2639-8028
    ISSN (online) 2639-8028
    DOI 10.1097/CCE.0000000000000882
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Nutritional support for critically ill patients with COVID-19: New strategy for a new disease?

    Pardo, Emmanuel / Constantin, Jean-Michel / Bonnet, Francis / Verdonk, Franck

    Anaesthesia, critical care & pain medicine

    2020  Volume 39, Issue 6, Page(s) 738–739

    MeSH term(s) COVID-19/complications ; COVID-19/rehabilitation ; Contraindications ; Critical Care ; Critical Illness/therapy ; Energy Intake ; Enteral Nutrition/adverse effects ; Enteral Nutrition/methods ; Humans ; Malnutrition/etiology ; Malnutrition/therapy ; Nutritional Support/adverse effects ; Nutritional Support/methods ; Parenteral Nutrition ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-10-12
    Publishing country France
    Document type Letter
    ISSN 2352-5568
    ISSN (online) 2352-5568
    DOI 10.1016/j.accpm.2020.10.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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