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Article ; Online: Erythema migrans: Lyme disease does not need prolonged therapy.

Eldin, Carole / Hansmann, Yves

2022 Volume 23, Issue 3, Page(s) 271–272

MeSH term(s)	Humans ; Erythema Chronicum Migrans ; Lyme Disease
Language	English
Publishing date	2022-10-06
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	2061641-7
ISSN	1474-4457 ; 1473-3099
ISSN (online)	1474-4457
ISSN	1473-3099
DOI	10.1016/S1473-3099(22)00581-3
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Zs.A 5743: Show issues

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Article ; Online: Multiple itchy lesions after recent travel.

Eldin, Carole / Gautret, Philippe

BMJ (Clinical research ed.)

2021 Volume 372, Page(s) n231

MeSH term(s)	Adolescent ; Anthelmintics/therapeutic use ; Brazil ; Female ; France ; Humans ; Larva Migrans/diagnosis ; Larva Migrans/etiology ; Larva Migrans/therapy ; Pruritus/diagnosis ; Pruritus/etiology ; Pruritus/therapy ; Travel
Chemical Substances	Anthelmintics
Language	English
Publishing date	2021-02-24
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	1362901-3
ISSN	1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
ISSN (online)	1756-1833
ISSN	0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
DOI	10.1136/bmj.n231
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Ua VI Zs.10: Show issues

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Article ; Online: Correspondence: serum neutralization of SARS-CoV-2 Omicron sublineages BA.1, BA.2 and BA.5 in lung transplant recipients receiving prophylactic tixagevimab/cilgavimab.

Eldin, Carole / Nurtop, Elif / Coiffard, Benjamin / Colombini, Nathalie / Ninove, Laetitia / Priet, Stéphane / Barthélémy, Karine / Reynaud-Gaubert, Martine / de Lamballerie, Xavier

Infection

2024

Language	English
Publishing date	2024-04-07
Publishing country	Germany
Document type	Letter
ZDB-ID	185104-4
ISSN	1439-0973 ; 0300-8126 ; 0173-2129
ISSN (online)	1439-0973
ISSN	0300-8126 ; 0173-2129
DOI	10.1007/s15010-024-02258-1
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Zs.A 881: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 528: Show issues

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Article ; Online: Rickettsioses.

Eldin, Carole / Parola, Philippe

La Revue du praticien

2020 Volume 70, Issue 2, Page(s) 201–205

Abstract: Rickettsioses. Rickettsioses are caused by intracellular bacteria from order of rickettsiales. They are transmitted by arthropods, mainly ticks, lice, fleas or other species close to chiggers, mainly in tropical areas. Some rickettsioses are endemic in ... ...

Title translation	Rickettsioses.
Abstract	Rickettsioses. Rickettsioses are caused by intracellular bacteria from order of rickettsiales. They are transmitted by arthropods, mainly ticks, lice, fleas or other species close to chiggers, mainly in tropical areas. Some rickettsioses are endemic in France and others can be seen in patients returning from travel, including those presenting with "fever of unknown origin". Rickettsiae can't be isolated by conventional blood cultures in the laboratory. The diagnosis of rickettsial diseases is often made by serology, but specific PCR based on the swab of an inoculation eschar when it is present is a simple and rapid tool. The standard treatment for rickettsioses is doxycycline, that should be started as soon as clinical suspicion occurs, before diagnostic confirmation since some rickettsial diseases can be fatal.
MeSH term(s)	Fever ; France ; Humans ; Rickettsia ; Rickettsia Infections ; Travel
Language	French
Publishing date	2020-09-02
Publishing country	France
Document type	Journal Article ; Review
ZDB-ID	205365-2
ISSN	2101-017X ; 0035-2640
ISSN (online)	2101-017X
ISSN	0035-2640
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Ua VI Zs.433: Show issues

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Article ; Online: When the patient is making the (wrong?) diagnosis: a biographical approach to patients consulting for presumed Lyme disease.

Lutaud, Romain / Verger, Pierre / Peretti-Watel, Patrick / Eldin, Carole

Family practice

2022

Abstract: Background: Media coverage of Lyme disease (LD) has led to an increase in consultations for presumed LD in Europe. However, LD is confirmed in only 10%-20% of patients, with a significant number remaining in a diagnostic dead-end.: Objectives: To ... ...

Abstract	Background: Media coverage of Lyme disease (LD) has led to an increase in consultations for presumed LD in Europe. However, LD is confirmed in only 10%-20% of patients, with a significant number remaining in a diagnostic dead-end. Objectives: To reach a deeper understanding of how patients themselves contribute to the diagnostic process. To describe the genesis of the LD hypothesis in care pathways. Methods: In 2019, 30 patients from a prospective cohort consulting in the infectious diseases department at University Hospital in Marseille for presumed LD were recruited for semistructured interviews. The inclusion criteria were: suffering from subjective symptoms for 6 months, no clinical or paraclinical argument suggesting current LD. The patients' medical trajectories were collected using a biographical approach. Results: The diagnosis of LD was primarily triggered by identification with personal testimonies found on the Internet. Most of patients were leading their own diagnostic investigation. The majority of participants were convinced they had LD despite the lack of medical evidence and the scepticism of their referring GP. Conclusion: GPs should first systematically explore patients' aetiologic representations in order to improve adherence to the diagnosis especially in the management of medically unexplained symptoms. Long COVID-19 syndrome challenge offers an opportunity to promote active patient involvement in diagnosis.
Language	English
Publishing date	2022-10-21
Publishing country	England
Document type	Journal Article
ZDB-ID	605939-9
ISSN	1460-2229 ; 0263-2136
ISSN (online)	1460-2229
ISSN	0263-2136
DOI	10.1093/fampra/cmac116
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Zs.A 2021: Show issues

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Article ; Online: Erythema Migrans Caused by Borrelia spielmanii, France.

Del Giudice, Pascal / Freychet, Fabienne / Kopec, Lora / Fenollar, Florence / Eldin, Carole / Velin, Marine / Hubiche, Thomas / Raoult, Didier / Mediannikov, Oleg

Emerging infectious diseases

2023 Volume 29, Issue 11, Page(s) 2366–2369

Abstract: We describe a rare case of early Lyme borreliosis in France caused by Borrelia spielmanii, which manifested as a large erythema chronicum migrans rash. The patient completely recovered after a 15-day course of amoxicillin. Absence of pathognomonic signs ... ...

Abstract	We describe a rare case of early Lyme borreliosis in France caused by Borrelia spielmanii, which manifested as a large erythema chronicum migrans rash. The patient completely recovered after a 15-day course of amoxicillin. Absence of pathognomonic signs prevented distinguishing B. spielmanii from other etiologies as cause in this case-patient.
MeSH term(s)	Humans ; Erythema Chronicum Migrans/diagnosis ; Erythema Chronicum Migrans/drug therapy ; Lyme Disease/diagnosis ; Lyme Disease/drug therapy ; Spirochaetales ; Amoxicillin/therapeutic use
Chemical Substances	Amoxicillin (804826J2HU)
Language	English
Publishing date	2023-11-08
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	1380686-5
ISSN	1080-6059 ; 1080-6040
ISSN (online)	1080-6059
ISSN	1080-6040
DOI	10.3201/eid2911.230149
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Zs.A 4778: Show issues

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Article: Update on Tick-Borne Bacterial Diseases in Travelers.

Eldin, Carole / Parola, Philippe

Current infectious disease reports

2018 Volume 20, Issue 7, Page(s) 17

Abstract: Purpose of review: Ticks are the second most important vectors of infectious diseases after mosquitoes worldwide. The growth of international tourism including in rural and remote places increasingly exposes travelers to tick bite. Our aim was to review ...

Abstract	Purpose of review: Ticks are the second most important vectors of infectious diseases after mosquitoes worldwide. The growth of international tourism including in rural and remote places increasingly exposes travelers to tick bite. Our aim was to review the main tick-borne infectious diseases reported in travelers in the past 5 years. Recent findings: In recent years, tick-borne bacterial diseases have emerged in travelers including spotted fever group (SFG) rickettsioses, borrelioses, and diseases caused by bacteria of the Anaplasmataceae family. African tick-bite fever, due to Rickettsia africae, is the most frequent agent reported in travelers returned from Sub-Saharan areas. Other SFG agents are increasingly reported in travelers, and clinicians should be aware of them. Lyme disease can be misdiagnosed in Southern countries. Organisms causing tick-borne relapsing fever are neglected pathogens worldwide, and reports in travelers have allowed the description of new species. Infections due to Anaplasmataceae bacteria are more rarely described in travelers, but a new species of Neoehrlichia has recently been detected in a traveler. The treatment of these infections relies on doxycycline, and travelers should be informed before the trip about prevention measures against tick bites.
Language	English
Publishing date	2018-05-22
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2019948-X
ISSN	1534-3146 ; 1523-3847
ISSN (online)	1534-3146
ISSN	1523-3847
DOI	10.1007/s11908-018-0624-y
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Zs.A 5519: Show issues

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Article ; Online: Infection à virus West Nile : une arbovirose émergente en France et en Europe.

Eldin, Carole / Ninove, Laetitia / Lagier, Jean-Christophe

La Revue du praticien

2020 Volume 70, Issue 3, Page(s) 333–335

Abstract: West nile virus infection: an emerging arbovirosis in france and europe. West Nile virus is a mosquito-borne flavivirus, transmitted to humans by mosquitoes of the genus Culex, from an avian reservoir. Humans are accidental hosts and there is no report ... ...

Title translation	West Nile virus infection: an emerging arbovirosis in France and Europe.
Abstract	West nile virus infection: an emerging arbovirosis in france and europe. West Nile virus is a mosquito-borne flavivirus, transmitted to humans by mosquitoes of the genus Culex, from an avian reservoir. Humans are accidental hosts and there is no report of human-to-human transmission, except via blood transfusion or organ transplantation. In 2018, Europe experienced the largest outbreak of West Nile virus infection ever. In France, 27 cases were identified including 7 neuro invasive forms. This infection is asymptomatic in most cases but may also manifest as an isolated fever or flu-like syndrome. In about 1% of cases, neuro-invasive forms with meningitis, meningoencephalitis or flaccid paralysis can be observed. There is no specific treatment for this viral infection. Prevention is based on the prevention of mosquito bites, but also on enhanced epidemiological surveillance during the period of circulation of the virus in Europe (from spring to autumn).
MeSH term(s)	Animals ; Communicable Diseases, Emerging ; Culex ; Europe/epidemiology ; France/epidemiology ; Humans ; West Nile Fever/epidemiology ; West Nile virus
Language	French
Publishing date	2020-09-02
Publishing country	France
Document type	Journal Article
ZDB-ID	205365-2
ISSN	2101-017X ; 0035-2640
ISSN (online)	2101-017X
ISSN	0035-2640
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Article ; Online: Borrélioses et fièvres récurrentes.

Raffetin, Alice / Patrat-Delon, Solène / Cazorla, Céline / Tattevin, Pierre / Eldin, Carole

La Revue du praticien

2022 Volume 71, Issue 10, Page(s) 1113–1117

Abstract: BORRELIOSIS AND RELAPSING feverrelapsing fevers borreliosis (RFB) are caused by bacteria of the genus Borrelia, within the spirochete's family, transmitted to Humans by arthropods (lice Pediculus humanus, soft ticks of the genus Ornithodoros, or hard ... ...

Title translation	Borreliosis and relapsing fever.
Abstract	BORRELIOSIS AND RELAPSING feverrelapsing fevers borreliosis (RFB) are caused by bacteria of the genus Borrelia, within the spirochete's family, transmitted to Humans by arthropods (lice Pediculus humanus, soft ticks of the genus Ornithodoros, or hard ticks for one of them). The RFB transmitted by body lice is cosmopolitan and occurs during epidemics in the context of major crises (promiscuity, precarious hygiene conditions, food crises, etc.). RFB transmitted by ticks are distributed by region, according to the Borrelia species and the geographical repartition of the tick involved (sporadic transmission). The incubation period varies from 3 to 20 days. The first febrile phase lasts 3 days (1-14 days), followed by a phase of apyrexia with persistence of other clinical signs (skin rash, petechiae, headaches, agitation, polyarthromyalgia, abdominal pain, nausea/vomiting, etc.). The recurrence of fever occurs every 7 days on average. Bacteremia in the blood is abundant during fever allowing direct diagnosis by microscopy, Borrelia PCR or culture on a specific medium when available. The first-line treatment is doxycycline, except in case of neurological involvement (ceftriaxone). The mortality Rate varies from 2 to 5 % depending on the Borrelia Species involved. The outcome is usually good after treatment.
MeSH term(s)	Animals ; Borrelia/genetics ; Humans ; Ornithodoros ; Polymerase Chain Reaction ; Relapsing Fever/diagnosis ; Relapsing Fever/drug therapy ; Relapsing Fever/epidemiology
Language	French
Publishing date	2022-02-11
Publishing country	France
Document type	Journal Article
ZDB-ID	205365-2
ISSN	2101-017X ; 0035-2640
ISSN (online)	2101-017X
ISSN	0035-2640
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Article ; Online: Clinical patterns of somatic symptoms in patients suffering from post-acute long COVID: a systematic review.

Nguyen, Nhu Ngoc / Hoang, Van Thuan / Dao, Thi Loi / Dudouet, Pierre / Eldin, Carole / Gautret, Philippe

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

2022 Volume 41, Issue 4, Page(s) 515–545

Abstract: Background: Long COVID-19 may affect patients after hospital discharge.: Aims: This study aims to describe the burden of the long-term persistence of clinical symptoms in COVID-19 patients.: Methods: We conducted a systematic review by using the ... ...

Abstract	Background: Long COVID-19 may affect patients after hospital discharge. Aims: This study aims to describe the burden of the long-term persistence of clinical symptoms in COVID-19 patients. Methods: We conducted a systematic review by using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guideline. The PubMed and Google Scholar databases were searched for studies that included information on the prevalence of somatic clinical symptoms lasting at least 4 weeks after the onset of a PCR- or serology-confirmed diagnosis of COVID-19. The prevalence of persisting clinical symptoms was assessed and risk factors were described when investigated. Psychological symptoms and cognitive disorders were not evaluated in this study. Results: Thirty-seven articles met the inclusion criteria. Eighteen studies involved in-patients only with a duration of follow-up of either less than 12 weeks, 12 weeks to 6 months, or more. In these studies, fatigue (16-64%), dyspnea (15-61%), cough (2-59%), arthralgia (8-55%), and thoracic pain (5-62%) were the most frequent persisting symptoms. In nineteen studies conducted in a majority of out-patients, the persistence of these symptoms was lower and 3% to 74% of patients reported prolonged smell and taste disorders. The main risk factors for persisting symptoms were being female, older, having comorbidities and severity at the acute phase of the disease. Conclusion: COVID-19 patients should have access to dedicated multidisciplinary healthcare allowing a holistic approach. Effective outpatient care for patients with long-COVID-19 requires coordination across multiple sub-specialties, which can be proposed in specialized post-COVID units.
MeSH term(s)	COVID-19/complications ; COVID-19/epidemiology ; Fatigue/epidemiology ; Fatigue/etiology ; Female ; Humans ; Medically Unexplained Symptoms ; SARS-CoV-2
Language	English
Publishing date	2022-02-10
Publishing country	Germany
Document type	Journal Article ; Review ; Systematic Review
ZDB-ID	603155-9
ISSN	1435-4373 ; 0934-9723 ; 0722-2211
ISSN (online)	1435-4373
ISSN	0934-9723 ; 0722-2211
DOI	10.1007/s10096-022-04417-4
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