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  1. Article: Probiotics, prebiotics, and COVID-19 infection: A review article.

    Khaled, Jamal M A

    Saudi journal of biological sciences

    2020  Volume 28, Issue 1, Page(s) 865–869

    Abstract: The beneficial live microbes of humans and animals are termed probiotics, and the chemical compounds that improve the growth of probiotics are known as prebiotics. Paraprobiotics and postbiotics refer to dead or inactivated living cells of probiotics and ...

    Abstract The beneficial live microbes of humans and animals are termed probiotics, and the chemical compounds that improve the growth of probiotics are known as prebiotics. Paraprobiotics and postbiotics refer to dead or inactivated living cells of probiotics and healthful metabolic products that are produced by the living cells of probiotics, respectively. Although the healthful, functional, nutritional, and immune benefits of probiotics and prebiotics are scientifically well established beyond a reasonable doubt, their potential biological roles against COVID-19 infection still warrant further clinical and laboratory investigation.
    Language English
    Publishing date 2020-11-09
    Publishing country Saudi Arabia
    Document type Journal Article ; Review
    ZDB-ID 2515206-3
    ISSN 2213-7106 ; 1319-562X
    ISSN (online) 2213-7106
    ISSN 1319-562X
    DOI 10.1016/j.sjbs.2020.11.025
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  2. Article: The Prevalence of the Virulence Genes of

    Abdulmanea, Adel A / Alharbi, Naiyf S / Somily, Ali M / Khaled, Jamal M / Algahtani, Farjah H

    Antibiotics (Basel, Switzerland)

    2023  Volume 12, Issue 7

    Abstract: Staphylococcus ... ...

    Abstract Staphylococcus aureus
    Language English
    Publishing date 2023-07-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics12071221
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Probiotics, prebiotics, and COVID-19 infection

    Jamal M.A. Khaled

    Saudi Journal of Biological Sciences, Vol 28, Iss 1, Pp 865-

    A review article

    2021  Volume 869

    Abstract: The beneficial live microbes of humans and animals are termed probiotics, and the chemical compounds that improve the growth of probiotics are known as prebiotics. Paraprobiotics and postbiotics refer to dead or inactivated living cells of probiotics and ...

    Abstract The beneficial live microbes of humans and animals are termed probiotics, and the chemical compounds that improve the growth of probiotics are known as prebiotics. Paraprobiotics and postbiotics refer to dead or inactivated living cells of probiotics and healthful metabolic products that are produced by the living cells of probiotics, respectively. Although the healthful, functional, nutritional, and immune benefits of probiotics and prebiotics are scientifically well established beyond a reasonable doubt, their potential biological roles against COVID-19 infection still warrant further clinical and laboratory investigation.
    Keywords Probiotics ; Prebiotics ; Paraprobiotics ; Postbiotics ; COVID-19 ; SARS-CoV-2 ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Iron-tannic acid nano-coating: A promising treatment approach for enhancing

    Elmaghrabi, Marwa M / Alharbi, Naiyf S / Alobaidi, Ahmed S / Abdulmanea, Adel A / Kadaikunnan, Shine / Ramadan, Asmaa A / Khaled, Jamal M

    Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

    2024  Volume 32, Issue 5, Page(s) 102052

    Abstract: The objective of this study was to explore a novel methodology for the synthesis of nanocoated probiotics following their collection and cultivation under optimized conditions, in light of their significant contribution to human health. Probiotics are ... ...

    Abstract The objective of this study was to explore a novel methodology for the synthesis of nanocoated probiotics following their collection and cultivation under optimized conditions, in light of their significant contribution to human health. Probiotics are instrumental in sustaining immune health by modulating the gastrointestinal microbiota and facilitating digestion. However, the equilibrium they maintain can be adversely affected by antibiotic treatments. It is critical to investigate the vulnerability of probiotics to antibiotics, considering the potential implications. This research aimed to assess whether nanoparticle coating could augment the probiotics' resistance to antibiotic influence. A strain of
    Language English
    Publishing date 2024-03-27
    Publishing country Saudi Arabia
    Document type Journal Article
    ZDB-ID 1378024-4
    ISSN 1319-0164
    ISSN 1319-0164
    DOI 10.1016/j.jsps.2024.102052
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4758: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Probiotics, prebiotics, and COVID-19 infection

    Khaled, Jamal M.A.

    Saudi Journal of Biological Sciences ; ISSN 1319-562X

    A review article

    2020  

    Keywords General Agricultural and Biological Sciences ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.sjbs.2020.11.025
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Synthesis and characterization of marine seagrass (Cymodocea serrulata) mediated titanium dioxide nanoparticles for antibacterial, antibiofilm and antioxidant properties.

    Narayanan, Mohankumar / Srinivasan, Suganthi / Gnanasekaran, Chackaravarthi / Ramachandran, Govindan / Chelliah, Chenthis Kanisha / Rajivgandhi, Govindan / Maruthupandy, Muthuchamy / Quero, Franck / Li, Wen-Jun / Hayder, Gasim / Khaled, Jamal M / Arunachalam, Arulraj / Manoharan, Natesan

    Microbial pathogenesis

    2024  Volume 189, Page(s) 106595

    Abstract: Cymodocea serrulata mediated titanium dioxide nanoparticles ( ... ...

    Abstract Cymodocea serrulata mediated titanium dioxide nanoparticles (TiO
    MeSH term(s) Antioxidants/pharmacology ; Antioxidants/chemistry ; Methicillin-Resistant Staphylococcus aureus ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Nanoparticles/chemistry ; Biofilms ; Metal Nanoparticles/chemistry ; Titanium
    Chemical Substances Antioxidants ; titanium dioxide (15FIX9V2JP) ; Plant Extracts ; Anti-Bacterial Agents ; Titanium (D1JT611TNE)
    Language English
    Publishing date 2024-02-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 632772-2
    ISSN 1096-1208 ; 0882-4010
    ISSN (online) 1096-1208
    ISSN 0882-4010
    DOI 10.1016/j.micpath.2024.106595
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2136: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: The transmutation of Escherichia coli ATCC 25922 to small colony variants (SCVs) E. coli strain as a result of exposure to gentamicin.

    Noaman, Khaled A / Alharbi, Naiyf S / Khaled, Jamal M / Kadaikunnan, Shine / Alobaidi, Ahmed S / Almazyed, Abeer O / Aldosary, Mohammed S / Al Rashedi, Saeed

    Journal of infection and public health

    2023  Volume 16, Issue 11, Page(s) 1821–1829

    Abstract: Background: Small colony variants (SCVs) are biotypes of bacteria that have a size of approximately one-tenth or less of the wild types and has distinct characteristics comparing to the wild type strains. Clinical SCVs are usually associated with ... ...

    Abstract Background: Small colony variants (SCVs) are biotypes of bacteria that have a size of approximately one-tenth or less of the wild types and has distinct characteristics comparing to the wild type strains. Clinical SCVs are usually associated with persistent infection and require a long-term treatment program with antibiotics. In Saudi Arabia, there are few studies about SCVs Escherichia coli for this reason, this study is aimed to investigate the ability of gentamicin to mutate E. coli ATCC 25922 to produce small SCVs and investigate the genotypes and phenotypes changes and stress tolerance comparing to clinical SCVs E. coli and normal clinical E. coli Isolated from blood samples.
    Methods: In this investigation, four clinical blood samples were collected ted from patients and the cultivation and isolation were carried out in KFMC between December 2019 and February 2021. The identification of positive blood culture samples was done using phoenix MD. Non-SCV E. coli ATCC25922 were mutated to SCV using exposure to increasing gradual concentrations of gentamicin at 100-generation intervals. Biochemical features and susceptibility to standard antibiotics using automated Phoenix MD 50 and. The survival assays were done using several stresses including heat shock, low pH, high osmotic pressure, and oxidative pressure. Virulence genes screening included the detection of genes that encoded to α-haemolysin, CS12 fimbriae, F17-like fimbrial adhesion, P-related fimbriae, yersiniabactin siderophore system, P-fimbriae, aerobactin, iron-regulated genes using PCR and gel electrophoresis.
    Results: The data from the mutating E. coli ATCC 25922 small colony test with gentamicin revealed that the first emergence of the multidrug resistance (MDR) SCV E. coli strain occurred at generation number 250, corresponding to a gentamicin concentration of 57 g/ml. Pathogenicity islands detection revealed that all tested E. coli strains have PAI IV 536 genes on their chromosomes furthermore, mutated SCV E. coli ATCC 25922 acquired PAII CFT
    Conclusion: The present work concluded that gentamicin sub-MIC concentration gradual exposure can induce mutation responsible for SCV formation and evolving of MDR E. coli strains. The mutated SCVs evolved high-level aminoglycoside resistance for gentamicin and resistance to amikacin, it also developed resistance to 2 cephalosporin antibiotics cefuroxime, and cephalothin and a resistance to aztreonam.
    Language English
    Publishing date 2023-09-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2467587-8
    ISSN 1876-035X ; 1876-0341
    ISSN (online) 1876-035X
    ISSN 1876-0341
    DOI 10.1016/j.jiph.2023.08.024
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  8. Article ; Online: First report on morphological and molecular characteristics of eight Agaricomycotina mushrooms in Saudi Arabia

    Jamal M. Khaled / Naiyf S. Alharbi / Ramzi A. Mothana / Shine Kadaikunnan / Ahmed S. Alobaidi

    Journal of King Saud University: Science, Vol 34, Iss 8, Pp 102345- (2022)

    2022  

    Abstract: Some fruiting body fungi, such as mushrooms, have valuable nutritional and medicinal properties. The present study aimed to report some mushroom species for the first time in several regions of Saudi Arabia: Abha, Al-Baha, Al-Taif, and Jeddah. ... ...

    Abstract Some fruiting body fungi, such as mushrooms, have valuable nutritional and medicinal properties. The present study aimed to report some mushroom species for the first time in several regions of Saudi Arabia: Abha, Al-Baha, Al-Taif, and Jeddah. Morphological and microscopic features, the internal transcribed spacer (ITS) region, and a Basic Local Alignment Search Tool (BLAST) analysis were studied to identify Crinipellis scabella, Parasola conopilea, Agrocybe pediades, Pyrofomes demidoffii, and Tulostoma fimbriatum in Al-Baha, and Conocybe macrospora, and Chlorophyllum palaeotropicum throughout Saudi Arabia. All mushrooms identified in this present work were Agaricomycotina mushrooms recorded for the first time in Saudi Arabia.
    Keywords Agaricomycotina ; Mushrooms ; Fruiting body fungi ; Molecular phylogeny ; Science (General) ; Q1-390
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Biochemical Profile by GC-MS of Fungal Biomass Produced from the Ascospores of

    Khaled, Jamal M / Alharbi, Naiyf S / Mothana, Ramzi A / Kadaikunnan, Shine / Alobaidi, Ahmed S

    Journal of fungi (Basel, Switzerland)

    2021  Volume 7, Issue 12

    Abstract: The edible fruiting bodies of desert truffles are seasonally collected and consumed in many regions of the world. Although they are very expensive, they are bought and sold as a result of considerable scientific reports confirming their health and ... ...

    Abstract The edible fruiting bodies of desert truffles are seasonally collected and consumed in many regions of the world. Although they are very expensive, they are bought and sold as a result of considerable scientific reports confirming their health and nutritional benefits. This study aimed to conduct laboratory production of the fungal biomass of
    Language English
    Publishing date 2021-12-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof7121083
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  10. Article ; Online: Association between 17q21 variants and asthma predisposition in Pashtun population from Pakistan.

    Afzal, Sibtain / Ramzan, Khushnooda / Ullah, Sajjad / Jamal, Arshad / Basit, Sulman / AlKattan, Khaled M / Waqar, Ahmed Bilal

    The Journal of asthma : official journal of the Association for the Care of Asthma

    2022  Volume 60, Issue 1, Page(s) 63–75

    Abstract: Objective: Asthma is a heterogeneous and genetically complex respiratory disease, and more than 300 million people are affected worldwide. In this study, frequencies of four SNPs (rs3816470, rs7216389, rs8067378, rs12603332) in chromosome 17q21 region ... ...

    Abstract Objective: Asthma is a heterogeneous and genetically complex respiratory disease, and more than 300 million people are affected worldwide. In this study, frequencies of four SNPs (rs3816470, rs7216389, rs8067378, rs12603332) in chromosome 17q21 region were analyzed and their relationship with the asthma susceptibility, in the Pashtun population of Khyber Pakhtunkhwa province (KPK) of Pakistan were investigated.
    Methods: DNA samples from 500 subjects (asthma cases/controls) were genotyped by Sanger sequencing. Chi-square tests, logistic regression analysis, linkage disequilibrium, and haplotype analysis techniques were applied to study the association of the SNPs with asthma.
    Results: Genetic models, including recessive, dominant, co-dominant, over-dominant, and additive, were tested. The frequencies of alleles T/T at rs3816470 (OR = 1.91; 95%CI = 1.15-3.18;
    Conclusion: The 17q21 variants (rs3816470, rs7216389, rs12603332) were found significantly (
    Supplemental data for this article can be accessed.
    MeSH term(s) Humans ; Male ; Female ; Genetic Predisposition to Disease ; Pakistan/epidemiology ; Asthma/epidemiology ; Asthma/genetics ; Case-Control Studies ; Genotype ; Polymorphism, Single Nucleotide
    Language English
    Publishing date 2022-01-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 603816-5
    ISSN 1532-4303 ; 0277-0903
    ISSN (online) 1532-4303
    ISSN 0277-0903
    DOI 10.1080/02770903.2021.2025391
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 18: Show issues Location:
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