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  1. Article ; Online: Probiotics and COVID-19 - Authors' reply.

    Mak, Joyce W Y / Chan, Francis K L / Ng, Siew C

    The lancet. Gastroenterology & hepatology

    2020  Volume 5, Issue 8, Page(s) 722–723

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; Probiotics ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-13
    Publishing country Netherlands
    Document type Letter ; Comment
    ISSN 2468-1253
    ISSN (online) 2468-1253
    DOI 10.1016/S2468-1253(20)30197-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Cost-effectiveness of internet-supported cognitive behavioral therapy for university students with anxiety symptoms: A Markov-model analysis.

    You, Joyce H S / Luk, Scotty W C / Chow, Dilys Y W / Jiang, Xinchan / Mak, Arthur D P / Mak, Winnie W S

    PloS one

    2022  Volume 17, Issue 5, Page(s) e0268061

    Abstract: Background and aim: High prevalence of anxiety symptoms has been reported globally in the university students. Cognitive behavioral therapy (CBT) is the recognized treatment for anxiety and is traditionally conducted face-to-face (f-CBT). The efficacy ... ...

    Abstract Background and aim: High prevalence of anxiety symptoms has been reported globally in the university students. Cognitive behavioral therapy (CBT) is the recognized treatment for anxiety and is traditionally conducted face-to-face (f-CBT). The efficacy of internet-based CBT (i-CBT) for anxiety has been extensively studied, yet evidence on its cost-effectiveness is scarce. We aimed to evaluate the cost-effectiveness of guided low-intensity i-CBT for university students with mild anxiety symptoms from the societal perspective of Hong Kong.
    Methods: A 5-year Markov model was designed to compare outcomes of guided i-CBT and f-CBT in a hypothetical cohort of university students with mild anxiety symptoms. Model inputs of cost and healthcare resources associated with anxiety were retrospectively collected from a cohort of university students with anxiety symptoms. Clinical and utility model inputs were retrieved from published literature. Model outcome measures were anxiety-related total cost (including direct medical and indirect costs) and quality-adjusted life-year (QALY). Sensitivity analyses were performed to examine the robustness of base-case results.
    Results: In base-case analysis, i-CBT gained higher QALYs (2.9956 versus 2.9917) at lower total cost (US$6,101 versus US$6,246) than f-CBT. In one-way sensitivity analysis, the QALY gained by i-CBT was sensitive to the relative patient acceptance and adherence to CBT. In probabilistic sensitivity analysis, i-CBT was cost-effective in 90.9% of the time at the willingness-to-pay threshold of 138,210 per QALY (3× GDP per capita in Hong Kong). The probability of i-CBT to be cost-effective was 99.9% at a willingness-to-pay threshold of zero.
    Conclusions: Guided i-CBT appears to be cost-saving and effective for management of university students with mild symptoms of anxiety from the societal perspective of Hong Kong. The cost-effectiveness of i-CBT is highly subject to the individual acceptance and adherence of CBT delivered by the internet platform.
    MeSH term(s) Anxiety/therapy ; Cognitive Behavioral Therapy/methods ; Cost-Benefit Analysis ; Humans ; Internet ; Quality-Adjusted Life Years ; Retrospective Studies ; Students ; Universities
    Language English
    Publishing date 2022-05-05
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0268061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Probiotics and COVID-19: one size does not fit all.

    Mak, Joyce W Y / Chan, Francis K L / Ng, Siew C

    The lancet. Gastroenterology & hepatology

    2020  Volume 5, Issue 7, Page(s) 644–645

    MeSH term(s) Betacoronavirus ; COVID-19 ; China ; Coronavirus Infections/complications ; Coronavirus Infections/drug therapy ; Coronavirus Infections/microbiology ; Coronavirus Infections/therapy ; Diarrhea/chemically induced ; Diarrhea/microbiology ; Diarrhea/therapy ; Humans ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/microbiology ; Pneumonia, Viral/therapy ; Probiotics/therapeutic use ; SARS-CoV-2 ; Treatment Outcome
    Keywords covid19
    Language English
    Publishing date 2020-04-25
    Publishing country Netherlands
    Document type Letter
    ISSN 2468-1253
    ISSN (online) 2468-1253
    DOI 10.1016/S2468-1253(20)30122-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Management of bronchopleural fistula with endobronchial valve in hybrid operating room following transbronchial microwave ablation.

    Mak, Ka Lun / Chan, Joyce W Y / Lau, Rainbow W H / Ng, Calvin S H

    Interactive cardiovascular and thoracic surgery

    2021  Volume 33, Issue 6, Page(s) 992–994

    Abstract: Transbronchial microwave ablation for the treatment of lung nodules is gaining popularity. In the present case, transbronchial microwave ablation to a right middle lobe lesion was performed under electromagnetic navigation bronchoscopy guidance. It was ... ...

    Abstract Transbronchial microwave ablation for the treatment of lung nodules is gaining popularity. In the present case, transbronchial microwave ablation to a right middle lobe lesion was performed under electromagnetic navigation bronchoscopy guidance. It was complicated with pneumothorax and persistent air leak despite chest drainage and chemical pleurodesis. A diagnosis of bronchopleural fistula was reached and an endobronchial valve was implanted to the middle lobe segmental bronchus with almost immediate cessation of air leak. Our case demonstrated that endobronchial valve is safe and effective in managing bronchopleural fistula after transbronchial microwave ablation.
    MeSH term(s) Bronchial Fistula/diagnostic imaging ; Bronchial Fistula/etiology ; Bronchial Fistula/surgery ; Bronchoscopy ; Humans ; Microwaves/adverse effects ; Operating Rooms ; Pleural Diseases/diagnostic imaging ; Pleural Diseases/etiology ; Pleural Diseases/surgery ; Pneumothorax/diagnostic imaging ; Pneumothorax/etiology ; Pneumothorax/surgery
    Language English
    Publishing date 2021-07-13
    Publishing country England
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2095298-3
    ISSN 1569-9285 ; 1569-9293
    ISSN (online) 1569-9285
    ISSN 1569-9293
    DOI 10.1093/icvts/ivab183
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5730: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Probiotics and COVID-19

    Mak, Joyce W Y / Chan, Francis K L / Ng, Siew C

    The Lancet Gastroenterology & Hepatology

    one size does not fit all

    2020  Volume 5, Issue 7, Page(s) 644–645

    Keywords Hepatology ; Gastroenterology ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2468-1253
    DOI 10.1016/s2468-1253(20)30122-9
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

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  6. Article ; Online: Probiotics and COVID-19 – Authors' reply

    Mak, Joyce W Y / Chan, Francis K L / Ng, Siew C

    The Lancet Gastroenterology & Hepatology

    2020  Volume 5, Issue 8, Page(s) 722–723

    Keywords Hepatology ; Gastroenterology ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2468-1253
    DOI 10.1016/s2468-1253(20)30197-7
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: Effectiveness of prophylactic clipping in preventing postpolypectomy bleeding in oral anticoagulant users: a propensity-score analysis.

    Lau, Louis H S / Guo, Cosmos L T / Lee, Joyce K K / Chan, Clive S T / Mak, Joyce W Y / Wong, Sunny H / Yip, Terry C F / Wong, Grace L H / Wong, Vincent W S / Chan, Francis K L / Tang, Raymond S Y

    Gastrointestinal endoscopy

    2022  Volume 96, Issue 3, Page(s) 530–542.e1

    Abstract: Background and aims: Evidence of prophylactic clipping is inconsistent except for proximal and large colonic lesions in the general population. Although warfarin and direct oral anticoagulants (DOACs) are significant risk factors of postpolypectomy ... ...

    Abstract Background and aims: Evidence of prophylactic clipping is inconsistent except for proximal and large colonic lesions in the general population. Although warfarin and direct oral anticoagulants (DOACs) are significant risk factors of postpolypectomy bleeding (PPB), dedicated studies to examine the benefit of prophylactic clipping in these high-risk patients remain limited.
    Methods: We performed a propensity score-weighted retrospective cohort study from 2012 to 2020. Patients who received an oral anticoagulant and underwent colonoscopic polypectomy were included. Data were collected on baseline demographics, medications (anticoagulant, antiplatelet, and heparin bridging), and endoscopies (polyp number, location, size, morphology, histopathology, resection method and prophylactic clipping). Propensity-score models with inverse probability of treatment weighting were developed between prophylactic clipping and no clipping groups. Unbalanced variables were included in a doubly robust model with multivariate analysis. The primary outcome was clinically significant delayed PPB, defined as a composite endpoint of hemoglobin drop ≥2 g/dL, blood transfusion, or repeat colonoscopy for hemostasis within 30 days.
    Results: Five hundred forty-seven patients with 1485 polyps were included. Prophylactic clipping was not associated with a reduced risk of PPB (odds ratio [OR], 1.19; 95% confidence interval [CI], .73-1.95; P = .497). The hot resection method was associated with a significantly higher risk of PPB (OR, 9.76; 95% CI, 3.94-32.60; P < .001) compared with cold biopsy or snare polypectomy. In a subgroup analysis, prophylactic clipping was associated with a lower PPB risk in patients on DOACs (OR, .36; 95% CI, .16-.82; P = .015).
    Conclusions: Prophylactic clipping was not associated with an overall reduced risk of PPB in patients on oral anticoagulants. The use of cold snare polypectomy should be maximized in anticoagulated patients.
    MeSH term(s) Anticoagulants ; Colonic Polyps/pathology ; Colonoscopy/methods ; Gastrointestinal Hemorrhage/chemically induced ; Gastrointestinal Hemorrhage/prevention & control ; Humans ; Postoperative Hemorrhage/epidemiology ; Postoperative Hemorrhage/etiology ; Postoperative Hemorrhage/prevention & control ; Propensity Score ; Retrospective Studies
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2022-04-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2022.04.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 283: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 519: Show issues

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  10. Article ; Online: Cost-effectiveness of internet-supported cognitive behavioral therapy for university students with anxiety symptoms

    Joyce H S You / Scotty W C Luk / Dilys Y W Chow / Xinchan Jiang / Arthur D P Mak / Winnie W S Mak

    PLoS ONE, Vol 17, Iss 5, p e

    A Markov-model analysis.

    2022  Volume 0268061

    Abstract: Background and aim High prevalence of anxiety symptoms has been reported globally in the university students. Cognitive behavioral therapy (CBT) is the recognized treatment for anxiety and is traditionally conducted face-to-face (f-CBT). The efficacy of ... ...

    Abstract Background and aim High prevalence of anxiety symptoms has been reported globally in the university students. Cognitive behavioral therapy (CBT) is the recognized treatment for anxiety and is traditionally conducted face-to-face (f-CBT). The efficacy of internet-based CBT (i-CBT) for anxiety has been extensively studied, yet evidence on its cost-effectiveness is scarce. We aimed to evaluate the cost-effectiveness of guided low-intensity i-CBT for university students with mild anxiety symptoms from the societal perspective of Hong Kong. Methods A 5-year Markov model was designed to compare outcomes of guided i-CBT and f-CBT in a hypothetical cohort of university students with mild anxiety symptoms. Model inputs of cost and healthcare resources associated with anxiety were retrospectively collected from a cohort of university students with anxiety symptoms. Clinical and utility model inputs were retrieved from published literature. Model outcome measures were anxiety-related total cost (including direct medical and indirect costs) and quality-adjusted life-year (QALY). Sensitivity analyses were performed to examine the robustness of base-case results. Results In base-case analysis, i-CBT gained higher QALYs (2.9956 versus 2.9917) at lower total cost (US$6,101 versus US$6,246) than f-CBT. In one-way sensitivity analysis, the QALY gained by i-CBT was sensitive to the relative patient acceptance and adherence to CBT. In probabilistic sensitivity analysis, i-CBT was cost-effective in 90.9% of the time at the willingness-to-pay threshold of 138,210 per QALY (3× GDP per capita in Hong Kong). The probability of i-CBT to be cost-effective was 99.9% at a willingness-to-pay threshold of zero. Conclusions Guided i-CBT appears to be cost-saving and effective for management of university students with mild symptoms of anxiety from the societal perspective of Hong Kong. The cost-effectiveness of i-CBT is highly subject to the individual acceptance and adherence of CBT delivered by the internet platform.
    Keywords Medicine ; R ; Science ; Q
    Subject code 310 ; 150
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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