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  1. Article: Probiotics as a Weapon in the Fight Against COVID-19.

    Stavropoulou, Elisavet / Bezirtzoglou, Eugenia

    Frontiers in nutrition

    2020  Volume 7, Page(s) 614986

    Language English
    Publishing date 2020-12-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2020.614986
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: COVID-19 Outbreak and Impact on Food Safety

    Elisavet Stavropoulou / Eugenia Bezirtzoglou

    Erciyes Medical Journal, Vol 43, Iss 1, Pp 1-

    2020  Volume 2

    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2020-12-01T00:00:00Z
    Publisher KARE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Probiotiques: bienfaits et méfaits.

    Stavropoulou, Elisavet / Emonet, Stéphane

    Revue medicale suisse

    2020  Volume 16, Issue 710, Page(s) 1916–1919

    Abstract: Probiotics are a big food and pharmaceutical industry today. The most widely used probiotics are Lactobacillus spp, Bifidobacterium spp, strains of Enterococcus spp, Streptococcus spp and yeasts such as Saccharomyces pp. Among the best-known indications ... ...

    Title translation Probiotics: benefits and harms.
    Abstract Probiotics are a big food and pharmaceutical industry today. The most widely used probiotics are Lactobacillus spp, Bifidobacterium spp, strains of Enterococcus spp, Streptococcus spp and yeasts such as Saccharomyces pp. Among the best-known indications are Clostridioides difficile colitis and diarrhea due to antibiotics, but probiotics are also proposed as adjuvants for atopic syndromes, autoimmune diseases, prevention and treatment of obesity, diabetes and cystic fibrosis, where dysbiosis play an important role. However, their use remains debated due to a lack of powerful data proving their effectiveness and their often-overlooked side effects.
    MeSH term(s) Anti-Bacterial Agents/adverse effects ; Diarrhea/microbiology ; Diarrhea/therapy ; Dysbiosis/microbiology ; Dysbiosis/therapy ; Humans ; Probiotics/adverse effects ; Probiotics/therapeutic use
    Chemical Substances Anti-Bacterial Agents
    Language French
    Publishing date 2020-10-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Eyes Wide Shut: A Cohort Study Questioning the Role of Fundoscopy in Infective Endocarditis Diagnosis.

    Stavropoulou, Elisavet / Guery, Benoit / Tzimas, Georgios / Guex-Crosier, Yan / Hoogewoud, Florence / Tozzi, Piergiorgio / Kirsch, Matthias / Monney, Pierre / Papadimitriou-Olivgeris, Matthaios

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2024  Volume 78, Issue 3, Page(s) 663–666

    Abstract: In this retrospective/prospective study, we assessed the role of fundoscopy in 711 episodes with suspected infective endocarditis (IE); 238 (33%) had IE. Ocular embolic events (retinal emboli or chorioretinitis/endophthalmitis) and Roth spots were found ... ...

    Abstract In this retrospective/prospective study, we assessed the role of fundoscopy in 711 episodes with suspected infective endocarditis (IE); 238 (33%) had IE. Ocular embolic events (retinal emboli or chorioretinitis/endophthalmitis) and Roth spots were found in 37 (5%) and 34 (5%) episodes, respectively, but had no impact on IE diagnosis.
    MeSH term(s) Humans ; Cohort Studies ; Retrospective Studies ; Prospective Studies ; Endocarditis/diagnosis ; Endocarditis, Bacterial/diagnostic imaging ; Embolism
    Language English
    Publishing date 2024-02-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciae067
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Probiotics in Medicine: A Long Debate.

    Stavropoulou, Elisavet / Bezirtzoglou, Eugenia

    Frontiers in immunology

    2020  Volume 11, Page(s) 2192

    Abstract: During the last years probiotics gained the attention of clinicians for their use in the prevention and treatment of multiple diseases. Probiotics main mechanisms of action include enhanced mucosal barrier function, direct antagonism with pathogens, ... ...

    Abstract During the last years probiotics gained the attention of clinicians for their use in the prevention and treatment of multiple diseases. Probiotics main mechanisms of action include enhanced mucosal barrier function, direct antagonism with pathogens, inhibition of bacterial adherence and invasion capacity in the intestinal epithelium, boosting of the immune system and regulation of the central nervous system. It is accepted that there is a mutual communication between the gut microbiota and the liver, the so-called "microbiota-gut-liver axis" as well as a reciprocal communication between the intestinal microbiota and the central nervous system through the "microbiota-gut-brain axis." Moreover, recently the "gut-lung axis" in bacterial and viral infections is considerably discussed for bacterial and viral infections, as the intestinal microbiota amplifies the alveolar macrophage activity having a protective role in the host defense against pneumonia. The importance of the normal human intestinal microbiota is recognized in the preservation of health. Disease states such as, infections, autoimmune conditions, allergy and other may occur when the intestinal balance is disturbed. Probiotics seem to be a promising approach to prevent and even reduce the symptoms of such clinical states as an adjuvant therapy by preserving the balance of the normal intestinal microbiota and improving the immune system. The present review states globally all different disorders in which probiotics can be given. To date, Stronger data in favor of their clinical use are provided in the prevention of gastrointestinal disorders, antibiotic-associated diarrhea, allergy and respiratory infections. We hereby discuss the role of probiotics in the reduction of the respiratory infection symptoms and we focus on the possibility to use them as an adjuvant to the therapeutic approach of the pandemic COVID-19. Nevertheless, it is accepted by the scientific community that more clinical studies should be undertaken in large samples of diseased populations so that the assessment of their therapeutic potential provide us with strong evidence for their efficacy and safety in clinical use.
    MeSH term(s) Bacteria/immunology ; Bacterial Adhesion/immunology ; Betacoronavirus/immunology ; Brain/immunology ; Brain/microbiology ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/immunology ; Coronavirus Infections/microbiology ; Coronavirus Infections/therapy ; Gastrointestinal Microbiome/immunology ; Humans ; Intestinal Mucosa/immunology ; Intestinal Mucosa/microbiology ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/immunology ; Pneumonia, Viral/microbiology ; Pneumonia, Viral/therapy ; Probiotics/therapeutic use ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-09-25
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2020.02192
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Probiotics in Medicine

    Elisavet Stavropoulou / Eugenia Bezirtzoglou

    Frontiers in Immunology, Vol

    A Long Debate

    2020  Volume 11

    Abstract: During the last years probiotics gained the attention of clinicians for their use in the prevention and treatment of multiple diseases. Probiotics main mechanisms of action include enhanced mucosal barrier function, direct antagonism with pathogens, ... ...

    Abstract During the last years probiotics gained the attention of clinicians for their use in the prevention and treatment of multiple diseases. Probiotics main mechanisms of action include enhanced mucosal barrier function, direct antagonism with pathogens, inhibition of bacterial adherence and invasion capacity in the intestinal epithelium, boosting of the immune system and regulation of the central nervous system. It is accepted that there is a mutual communication between the gut microbiota and the liver, the so-called “microbiota-gut-liver axis” as well as a reciprocal communication between the intestinal microbiota and the central nervous system through the “microbiota-gut-brain axis.” Moreover, recently the “gut-lung axis” in bacterial and viral infections is considerably discussed for bacterial and viral infections, as the intestinal microbiota amplifies the alveolar macrophage activity having a protective role in the host defense against pneumonia. The importance of the normal human intestinal microbiota is recognized in the preservation of health. Disease states such as, infections, autoimmune conditions, allergy and other may occur when the intestinal balance is disturbed. Probiotics seem to be a promising approach to prevent and even reduce the symptoms of such clinical states as an adjuvant therapy by preserving the balance of the normal intestinal microbiota and improving the immune system. The present review states globally all different disorders in which probiotics can be given. To date, Stronger data in favor of their clinical use are provided in the prevention of gastrointestinal disorders, antibiotic-associated diarrhea, allergy and respiratory infections. We hereby discuss the role of probiotics in the reduction of the respiratory infection symptoms and we focus on the possibility to use them as an adjuvant to the therapeutic approach of the pandemic COVID-19. Nevertheless, it is accepted by the scientific community that more clinical studies should be undertaken in large samples of diseased ...
    Keywords probiotics ; medicine ; intestine ; COVID-19 ; lung ; allergy ; Immunologic diseases. Allergy ; RC581-607
    Subject code 610
    Language English
    Publishing date 2020-09-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: The Role of the Microbiome in Connective-Tissue-Associated Interstitial Lung Disease and Pulmonary Vasculitis.

    Drakopanagiotakis, Fotios / Stavropoulou, Elisavet / Tsigalou, Christina / Nena, Evangelia / Steiropoulos, Paschalis

    Biomedicines

    2022  Volume 10, Issue 12

    Abstract: The microbiome can trigger and maintain immune-mediated diseases and is associated with the severity and prognosis of idiopathic pulmonary fibrosis, which is the prototype of interstitial lung diseases (ILDs). The latter can be a major cause of morbidity ...

    Abstract The microbiome can trigger and maintain immune-mediated diseases and is associated with the severity and prognosis of idiopathic pulmonary fibrosis, which is the prototype of interstitial lung diseases (ILDs). The latter can be a major cause of morbidity and mortality in patients with connective-tissue diseases (CTD). In the present review, we discuss the current evidence regarding microbiome in CTD-ILD and pulmonary vasculitis. In patients with rheumatoid arthritis (RA) the BAL microbiota is significantly less diverse and abundant, compared to healthy controls. These changes are associated with disease severity. In systemic sclerosis (SSc), gastrointestinal (GI)-dysbiosis is associated with ILD. Butyrate acid administration as a means of restoration of GI-microbiota has reduced the degree of lung fibrosis in animal models. Although related studies are scarce for SLE and Sjögren's syndrome, studies of the gut, oral and ocular microbiome provide insights into the pathogenesis of these diseases. In ANCA-associated vasculitis, disease severity and relapses have been associated with disturbed nasal mucosa microbiota, with immunosuppressive treatment restoring the microbiome changes. The results of these studies suggest however no causal relation. More studies of the lung microbiome in CTD-ILDs are urgently needed, to provide a better understanding of the pathogenesis of these diseases.
    Language English
    Publishing date 2022-12-09
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines10123195
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Microbial Community Structure among Honey Samples of Different Pollen Origin.

    Stavropoulou, Elisavet / Remmas, Nikolaos / Voidarou, Chrysoula Chrysa / Vrioni, Georgia / Konstantinidis, Theodoros / Ntougias, Spyridon / Tsakris, Athanasios

    Antibiotics (Basel, Switzerland)

    2023  Volume 12, Issue 1

    Abstract: Honey's antibacterial activity has been recently linked to the inhibitory effects of honey microbiota against a range of foodborne and human pathogens. In the current study, the microbial community structure of honey samples exerting pronounced ... ...

    Abstract Honey's antibacterial activity has been recently linked to the inhibitory effects of honey microbiota against a range of foodborne and human pathogens. In the current study, the microbial community structure of honey samples exerting pronounced antimicrobial activity was examined. The honey samples were obtained from different geographical locations in Greece and had diverse pollen origin (fir, cotton, fir-oak, and
    Language English
    Publishing date 2023-01-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics12010101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Human microbiota in aging and infection: A review

    Stavropoulou, Elisavet / Eugenia Bezirtzoglou

    Critical reviews in food science and nutrition. 2019 Feb. 21, v. 59, no. 4

    2019  

    Abstract: In most developed countries, ageing of the population started more than a century ago and it seems to be emerged in a wide range of developing countries as well. Moreover, research into ageing has moved forward in extremely rapidly rhythms nowadays, and ... ...

    Abstract In most developed countries, ageing of the population started more than a century ago and it seems to be emerged in a wide range of developing countries as well. Moreover, research into ageing has moved forward in extremely rapidly rhythms nowadays, and the scientific area is of great interest, as implications for nearly all sectors of society, including work, social, economic features, in addition to nutrition and health issues which are involved. The fragile elder population is affected and experienced more frequently infections than the younger population. Infections in elderly patients are of major medical importance because of hormonal changes, increased production of pro-inflammatory cytokines and chemokines, abnormalities of the telomeres which could cause a dysfunction of the immune system called immunosenescence and malnutrition.
    Keywords chemokines ; developed countries ; developing countries ; elderly ; immune system ; malnutrition ; microorganisms ; nutrition ; patients ; telomeres
    Language English
    Dates of publication 2019-0221
    Size p. 537-545.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 1037504-1
    ISSN 1549-7852 ; 1040-8398
    ISSN (online) 1549-7852
    ISSN 1040-8398
    DOI 10.1080/10408398.2017.1379469
    Database NAL-Catalogue (AGRICOLA)

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