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Article ; Online: Framework for policymaking on self-management of health by older adults using technologies.

Gauthier-Beaupré, Amélie / Kuziemsky, Craig / Battistini, Bruno J / Jutai, Jeffrey W

2024 Volume 22, Issue 1, Page(s) 32

Abstract: Background: During the coronavirus disease 2019 (COVID-19) pandemic, the use of information and communication technologies (ICTs) to support care management exponentially increased. Governments around the world adapted existing programs to meet the ... ...

Abstract	Background: During the coronavirus disease 2019 (COVID-19) pandemic, the use of information and communication technologies (ICTs) to support care management exponentially increased. Governments around the world adapted existing programs to meet the needs of patients. The reactivity of governments, however, led to changes that were inequitable, undermining groups such as older adults living with chronic diseases and disability. Policies that align with recent developments in ICTs can promote better health outcomes and innovation in care management. A framework for policymaking presents potential for overcoming barriers and gaps that exist in current policies. Objective: The goal of this study was to examine how well a provisional framework for policymaking represented the interactions between various components of government policymaking on older adults' self-management of chronic disease and disability using ICTs. Methods: Through an online survey, the study engaged policymakers from various ministries of the government of Ontario in the evaluation and revision of the framework. The data were analyzed using simple statistics and by interpreting written comments. Results: Nine participants from three ministries in the government of Ontario responded to the questionnaire. Overall, participants described the framework as useful and identified areas for improvement and further clarification. A revised version of the framework is presented. Conclusions: Through the revision exercise, our study confirmed the relevance and usefulness for a policymaking framework on the self-management of disease and disability of older adults' using ICTs. Further inquiries should examine the application of the framework to jurisdictions other than Ontario considering the dissociated nature of Canadian provincial healthcare systems.
MeSH term(s)	Humans ; Aged ; Self-Management ; Technology ; COVID-19 ; Communication ; Ontario
Language	English
Publishing date	2024-03-05
Publishing country	England
Document type	Journal Article
ZDB-ID	2101196-5
ISSN	1478-4505 ; 1478-4505
ISSN (online)	1478-4505
ISSN	1478-4505
DOI	10.1186/s12961-024-01119-5
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Conference proceedings: Proceedings of the Sixth International Conference on Endothelin

Battistini, Bruno

held at the Marriott-Chateau Champlain Hotel, Montreal, QC, Canada, October 10 - 13, 1999

(Endothelin ; 6 ; Journal of cardiovascular pharmacology ; 36, Suppl. 1)

2000

Event/congress	International Conference on Endothelin (6, 1999, Montréal)
Author's details	guest ed. Bruno Battistini
Series title	Endothelin ; 6 Journal of cardiovascular pharmacology ; 36, Suppl. 1
Collection
Keywords	Endothelins / congresses
Language	English
Size	S431 S. : Ill., graph. Darst.
Publisher	Lippincott Williams & Wilkins
Publishing place	Hagerstown, MD
Publishing country	United States
Document type	Book ; Conference proceedings
HBZ-ID	HT012856161
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

Shelf mark	Loan status	Location
Zs A 1471 -36,Suppl.1-	not available for loan	Zeitschriften-Lesesaal

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Article ; Online: Policymaker perspectives on self-management of disease and disabilities using information and communication technologies.

Gauthier-Beaupré, Amélie / Battistini, Bruno J / Kuziemsky, Craig / Jutai, Jeffrey W

Health research policy and systems

2023 Volume 21, Issue 1, Page(s) 52

Abstract: Background: Policies that support health self-management are malleable and highly dependent on various factors that influence governments. Within a world that is shifting toward digitalization due to pressures such as the COVID-19 pandemic and labor ... ...

Abstract	Background: Policies that support health self-management are malleable and highly dependent on various factors that influence governments. Within a world that is shifting toward digitalization due to pressures such as the COVID-19 pandemic and labor shortages, policymaking on older adults' self-management of chronic diseases and disability using information and communication technologies (ICTs) needs to be better understood. Using the province of Ontario, in Canada, as a case study, the research question was What is the environment that policymakers must navigate through in development and implementation of policies related to older adults' self-management of disease and disability using information and communication technologies (ICTs)? Methods: This study used a qualitative approach where public servants from 4 ministries within the government of Ontario were invited to participate in a 1-h, one-on-one, semi-structured interview. The audio-recorded interviews were based on an adapted model of the policy triangle, where the researcher asked questions about the influences from the different sources identified in the model. The interviews were later transcribed and analyzed using a deductive-inductive coding approach. Results: Ten participants across 4 different Ministries participated in the interviews. Participants shared insights on various aspects of context, process and actors that help shape the current content of policies. The analysis revealed that policies, in the form of programs, services, legislation and regulations, are the result of collaborations and dialogue between different actors and get developed and implemented via a set of complex government processes. In addition, policy actions come from a plethora of sectors which all get influenced by several predictable and unpredictable external pressures. Conclusions: The environment for policymaking in the government of Ontario regarding older adults' self-management of disease and disability using ICTs is one that is mostly reactive to external pressures, while organized within a set of complex processes and multi-sectoral collaborations. The present research helped us to understand the complexity of policymaking on the topic and highlights the need for increased foresight and proactive policymaking, regardless of which governments are in-place.
MeSH term(s)	Humans ; Aged ; COVID-19 ; Pandemics ; Self-Management ; Communication ; Ontario
Language	English
Publishing date	2023-06-14
Publishing country	England
Document type	Journal Article
ZDB-ID	2101196-5
ISSN	1478-4505 ; 1478-4505
ISSN (online)	1478-4505
ISSN	1478-4505
DOI	10.1186/s12961-023-01004-7
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Evolution of public health policy on healthcare self-management: the case of Ontario, Canada.

Gauthier-Beaupré, Amélie / Kuziemsky, Craig / Battistini, Bruno J / Jutai, Jeffrey W

BMC health services research

2023 Volume 23, Issue 1, Page(s) 248

Abstract: Background: As people live longer, they are at increased risk for chronic diseases and disability. Self-management is a strategy to improve health outcomes and quality of life of those who engage in it. This study sought to gain a better understanding ... ...

Abstract	Background: As people live longer, they are at increased risk for chronic diseases and disability. Self-management is a strategy to improve health outcomes and quality of life of those who engage in it. This study sought to gain a better understanding of the factors, including digital technology, that affect public health policy on self-management through an analysis of government policy in the most populous and multicultural province in Canada: Ontario. The overarching question guiding the study was: What factors have influenced the development of healthcare self-management policies over time? Methods: Archival research methods, combining document review and evaluation, were used to collect data from policy documents published in Ontario. The documents were analyzed using the READ approach, evaluated using a data extraction table, and synthesized into themes using the model for health policy analysis. Results: Between January 1, 1985, and May 5, 2022, 72 policy documents on self-management of health were retrieved from databases, archives, and grey literature. Their contents largely focussed on self-management of general chronic conditions, while 47% (n = 18/72) mention diabetes, and 3% (n = 2/72) focussed solely on older adults. Digital technologies were mentioned and were viewed as tools to support self-management in the context of healthcare delivery and enhancing healthcare infrastructure (i.e., telehealth or software in healthcare settings). The actors involved in the policy document creation included mostly Ontario government agencies and departments, and sometimes expert organizations, community groups and engaged stakeholders. The results suggest that several factors including pressures on the healthcare system, hybrid top-down and bottom-up policymaking, and political context have influenced the nature and implementation timing of self-management policy in Ontario. Conclusions: The policy documents on self-management of health reveal a positive evolution of the content discussed over time. The changes were shaped by an evolving context, both from a health and political perspective, within a dynamic system of interactions between actors. This research helps understand the factors that have shaped changes and suggests that a critical evidence-based approach on public health policy is needed in understanding processes involved in the development of healthcare self-management policies from the perspective of a democratic governing system.
MeSH term(s)	Humans ; Aged ; Ontario ; Quality of Life ; Public Policy ; Health Policy ; Delivery of Health Care
Language	English
Publishing date	2023-03-14
Publishing country	England
Document type	Journal Article
ZDB-ID	2050434-2
ISSN	1472-6963 ; 1472-6963
ISSN (online)	1472-6963
ISSN	1472-6963
DOI	10.1186/s12913-023-09191-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book: Endothelin and its inhibitors

Battistini, Bruno / Warner, Timothy D.

(Handbook of experimental pharmacology ; 152)

2001

Author's details	contributors B. Battistini ... Ed. Timothy D. Warner
Series title	Handbook of experimental pharmacology ; 152
Collection
Keywords	Endothelins ; Receptors, Endothelin / antagonists & inhibitors ; Receptors, Endothelin / physiology ; Endothelin ; Pharmakologischer Antagonist ; Rezeptor
Language	English
Size	XXIV, 532 S. : Ill., graph. Darst.
Publisher	Springer
Publishing place	Berlin u.a.
Publishing country	Germany
Document type	Book
HBZ-ID	HT012993106
ISBN	3-540-67985-5 ; 978-3-540-67985-1
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

Shelf mark	Loan status	Location
2001 A 2636	order for loan	Magazin
2004 A 6671	order for loan	Magazin

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Article ; Online: The combination of omics strategies to evaluate starter and probiotic strains in the Catharina sour Brazilian-style beer.

Herkenhoff, Marcos Edgar / Battistini, Carolina / Praia, Ana Beatriz / Rossini, Bruno Cesar / Dos Santos, Lucilene Delazari / Brödel, Oliver / Frohme, Marcus / Saad, Susana Marta Isay

Food research international (Ottawa, Ont.)

2023 Volume 167, Page(s) 112704

Abstract: Catharina sour, the first internationally recognized Brazilian beer, is characterized by fermentation with lactic acid bacteria (LAB), which may have probiotic potential, and the addition of fruit juice. This study aimed to evaluate the use of the ... ...

Abstract	Catharina sour, the first internationally recognized Brazilian beer, is characterized by fermentation with lactic acid bacteria (LAB), which may have probiotic potential, and the addition of fruit juice. This study aimed to evaluate the use of the starter Streptococcus thermophilus TH-4 (TH-4) and the probiotics Lacticaseibacillus paracasei F19 and 431, associated with Saccharomyces cerevisiae US-05, in the absence (control)/presence of passion fruit or peach juices. Evaluation proceeded during fermentation and storage by enumeration using pour-plate and qPCR; gene expressions of hop resistance; proteome by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS); and odor, flavor, and metabolome by Headspace Solid-Phase Microextraction (HS-SPME), coupled with the gas chromatography-mass spectrometry (GC-MS) analysis. We concluded that the strains studied are recommended for applications in sour beers, due to the presence of defense mechanisms like membrane adhesion and H + pump. Furthermore, HS-SPME/GC-MS indicated that the strains may contribute to the beer flavor and odor.
MeSH term(s)	Beer/analysis ; Brazil ; Chromatography, Liquid ; Tandem Mass Spectrometry ; Saccharomyces cerevisiae/metabolism ; Probiotics/analysis
Language	English
Publishing date	2023-03-21
Publishing country	Canada
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1111695-x
ISSN	1873-7145 ; 0963-9969
ISSN (online)	1873-7145
ISSN	0963-9969
DOI	10.1016/j.foodres.2023.112704
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: New 4-Aminoproline-Based Small Molecule Cyclopeptidomimetics as Potential Modulators of α

Sartori, Andrea / Bugatti, Kelly / Portioli, Elisabetta / Baiula, Monica / Casamassima, Irene / Bruno, Agostino / Bianchini, Francesca / Curti, Claudio / Zanardi, Franca / Battistini, Lucia

Molecules (Basel, Switzerland)

2021 Volume 26, Issue 19

Abstract: ... Integrin ... ...

Abstract	Integrin α
MeSH term(s)	Cell Adhesion/drug effects ; Humans ; Integrin alpha4beta1/antagonists & inhibitors ; Integrin alpha4beta1/chemistry ; Jurkat Cells ; Ligands ; Models, Molecular ; Oligopeptides/chemistry ; Oligopeptides/pharmacology ; Peptides, Cyclic/chemistry ; Peptides, Cyclic/pharmacology ; Peptidomimetics/chemistry ; Peptidomimetics/pharmacology ; Proline/analogs & derivatives ; Proline/chemistry ; Proline/pharmacology ; Protein Binding ; Protein Conformation
Chemical Substances	Integrin alpha4beta1 ; Ligands ; Oligopeptides ; Peptides, Cyclic ; Peptidomimetics ; aminoproline ; leucyl-aspartyl-valine (125850-12-6) ; Proline (9DLQ4CIU6V)
Language	English
Publishing date	2021-10-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules26196066
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Article ; Online: The combination of omics strategies to evaluate starter and probiotic strains in the Catharina sour Brazilian-style beer

Herkenhoff, Marcos Edgar / Battistini, Carolina / Praia, Ana Beatriz / Rossini, Bruno Cesar / dos Santos, Lucilene Delazari / Brödel, Oliver / Frohme, Marcus / Saad, Susana Marta Isay

Food Research International. 2023 May, v. 167 p.112704-

2023

Abstract	Catharina sour, the first internationally recognized Brazilian beer, is characterized by fermentation with lactic acid bacteria (LAB), which may have probiotic potential, and the addition of fruit juice. This study aimed to evaluate the use of the starter Streptococcus thermophilus TH‐4 (TH‐4) and the probiotics Lacticaseibacillus paracasei F19 and 431, associated with Saccharomyces cerevisiae US-05, in the absence (control)/presence of passion fruit or peach juices. Evaluation proceeded during fermentation and storage by enumeration using pour-plate and qPCR; gene expressions of hop resistance; proteome by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS); and odor, flavor, and metabolome by Headspace Solid-Phase Microextraction (HS-SPME), coupled with the gas chromatography–mass spectrometry (GC–MS) analysis. We concluded that the strains studied are recommended for applications in sour beers, due to the presence of defense mechanisms like membrane adhesion and H + pump. Furthermore, HS-SPME/GC-MS indicated that the strains may contribute to the beer flavor and odor.
Keywords	Saccharomyces cerevisiae ; Streptococcus thermophilus ; adhesion ; beers ; fermentation ; flavor ; food research ; fruit juices ; gas chromatography-mass spectrometry ; genes ; headspace analysis ; lactic acid ; liquid chromatography ; metabolome ; odors ; passion fruits ; peaches ; probiotics ; proteome ; solid phase microextraction ; tandem mass spectrometry ; Craft beer ; Probiotic ; qPCR ; Hop resistance genes
Language	English
Dates of publication	2023-05
Publishing place	Elsevier Ltd
Document type	Article ; Online
ZDB-ID	1111695-x
ISSN	1873-7145 ; 0963-9969
ISSN (online)	1873-7145
ISSN	0963-9969
DOI	10.1016/j.foodres.2023.112704
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

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Article ; Online: Shifting Towards α

Bugatti, Kelly / Bruno, Agostino / Arosio, Daniela / Sartori, Andrea / Curti, Claudio / Augustijn, Lisa / Zanardi, Franca / Battistini, Lucia

Chemistry (Weinheim an der Bergstrasse, Germany)

2020 Volume 26, Issue 59, Page(s) 13468–13475

Abstract: In recognition of the key role played by integrins in several life-threatening dysfunctions, the search for novel small-molecule probes that selectively recognize these surface receptors is still open and widely pursued. Inspired by previously ... ...

Abstract	In recognition of the key role played by integrins in several life-threatening dysfunctions, the search for novel small-molecule probes that selectively recognize these surface receptors is still open and widely pursued. Inspired by previously established aminoproline (Amp)-RGD based cyclopeptidomimetics with attracting α
MeSH term(s)	Integrin alphaVbeta3/chemistry ; Integrin beta Chains/chemistry ; Ligands ; Oligopeptides/chemistry ; Peptidomimetics ; Proline/analogs & derivatives ; Proline/chemistry
Chemical Substances	Integrin alphaVbeta3 ; Integrin beta Chains ; Ligands ; Oligopeptides ; Peptidomimetics ; aminoproline ; integrin beta6 ; Proline (9DLQ4CIU6V)
Language	English
Publishing date	2020-09-21
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1478547-X
ISSN	1521-3765 ; 0947-6539
ISSN (online)	1521-3765
ISSN	0947-6539
DOI	10.1002/chem.202002554
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Article ; Online: Acute cardiovascular effects of inhaled ambient particulate matter: Chemical composition-related oxidative stress, endothelin-1, blood pressure, and ST-segment changes in Wistar rats.

Vincent, Renaud / Kumarathasan, Premkumari / Goegan, Patrick / Bjarnason, Stephen G / Guénette, Josée / Karthikeyan, Subramanian / Thomson, Errol M / Adamson, Ian Y / Watkinson, William P / Battistini, Bruno / Miller, Frederick J

Chemosphere

2022 Volume 296, Page(s) 133933

Abstract: Short-term increases in particulate matter (PM) are associated with heightened morbidity and mortality from cardiovascular causes. Inhalation of PM is known to increase endothelin (ET)-1 levels. Yet, less is known about particle composition-related ... ...

Abstract	Short-term increases in particulate matter (PM) are associated with heightened morbidity and mortality from cardiovascular causes. Inhalation of PM is known to increase endothelin (ET)-1 levels. Yet, less is known about particle composition-related changes at the molecular level including the endothelinergic system and relationship with cardiovascular function changes. In this work, adult Wistar male rats were exposed for 4 h by nose-only inhalation to clean air, Ottawa urban particles (EHC-93, 48 mg/m
MeSH term(s)	Air Pollutants/analysis ; Animals ; Blood Pressure ; Endothelin-1/pharmacology ; Inhalation Exposure/adverse effects ; Lung ; Male ; Oxidative Stress ; Particle Size ; Particulate Matter/pharmacology ; Rats ; Rats, Wistar
Chemical Substances	Air Pollutants ; Endothelin-1 ; Particulate Matter
Language	English
Publishing date	2022-02-11
Publishing country	England
Document type	Journal Article
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2022.133933
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 2540: Show issues

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