Result 1 - 10 of total 160
2023
| Keywords | Life Science |
|---|---|
| Publishing country | nl |
| Document type | Book ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
2023
Abstract: Invited speaker: The 10th International Conference on Algal Biomass, Biofuels and Bioproducts (ABBB)’’ 12–14 June 2023 | Waikoloa Beach, Hawaii, ... ...
| Abstract | Invited speaker: The 10th International Conference on Algal Biomass, Biofuels and Bioproducts (ABBB)’’ 12–14 June 2023 | Waikoloa Beach, Hawaii, USA |
|---|---|
| Keywords | Life Science |
| Publishing country | nl |
| Document type | Book ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
BMJ open quality
2024 Volume 13, Issue 1
Abstract: Many patients who are at high risk of HIV transmission do not receive pre-exposure prophylaxis (PrEP). HIV risk counselling and PrEP initiation have historically been limited to outpatient settings. Here we describe a novel quality improvement project at ...
| Abstract | Many patients who are at high risk of HIV transmission do not receive pre-exposure prophylaxis (PrEP). HIV risk counselling and PrEP initiation have historically been limited to outpatient settings. Here we describe a novel quality improvement project at San Francisco's main safety-net hospital designed to incorporate universal screening for active HIV risk factors and PrEP initiation into standard inpatient care. Interventions included education sessions and dissemination of clinical materials to increase providers' knowledge and comfort with HIV risk screening, prevention counselling and prescribing PrEP. We implemented new workflows on the inpatient medicine service to encourage providers to universally screen all patients at the time of admission and initiate PrEP for appropriate patients during their hospitalisation. Over the first 9 months of the initiative, 14 inpatients were started on PrEP during their admission. As PrEP was initiated in particularly vulnerable patients, using inpatient admissions to engage at-risk patients in HIV prevention may help to reduce disparities in HIV outcomes. |
|---|---|
| MeSH term(s) | Humans ; HIV Infections/prevention & control ; Inpatients ; Pre-Exposure Prophylaxis ; Quality Improvement ; Anti-HIV Agents/therapeutic use |
| Chemical Substances | Anti-HIV Agents |
| Language | English |
| Publishing date | 2024-01-17 |
| Publishing country | England |
| Document type | Journal Article |
| ISSN | 2399-6641 |
| ISSN (online) | 2399-6641 |
| DOI | 10.1136/bmjoq-2023-002416 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
BMJ Open Quality, Vol 13, Iss
a quality improvement project
2024 Volume 1
Abstract: Many patients who are at high risk of HIV transmission do not receive pre-exposure prophylaxis (PrEP). HIV risk counselling and PrEP initiation have historically been limited to outpatient settings. Here we describe a novel quality improvement project at ...
| Abstract | Many patients who are at high risk of HIV transmission do not receive pre-exposure prophylaxis (PrEP). HIV risk counselling and PrEP initiation have historically been limited to outpatient settings. Here we describe a novel quality improvement project at San Francisco’s main safety-net hospital designed to incorporate universal screening for active HIV risk factors and PrEP initiation into standard inpatient care. Interventions included education sessions and dissemination of clinical materials to increase providers’ knowledge and comfort with HIV risk screening, prevention counselling and prescribing PrEP. We implemented new workflows on the inpatient medicine service to encourage providers to universally screen all patients at the time of admission and initiate PrEP for appropriate patients during their hospitalisation. Over the first 9 months of the initiative, 14 inpatients were started on PrEP during their admission. As PrEP was initiated in particularly vulnerable patients, using inpatient admissions to engage at-risk patients in HIV prevention may help to reduce disparities in HIV outcomes. |
|---|---|
| Keywords | Medicine (General) ; R5-920 |
| Subject code | 610 |
| Language | English |
| Publishing date | 2024-01-01T00:00:00Z |
| Publisher | BMJ Publishing Group |
| Document type | Article ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
2023 Volume 41, Issue 3, Page(s) 452–471
Abstract: The urge for food security and sustainability has advanced the field of microalgal biotechnology. Microalgae are microorganisms able to grow using (sun)light, fertilizers, sugars, ... ...
| Abstract | The urge for food security and sustainability has advanced the field of microalgal biotechnology. Microalgae are microorganisms able to grow using (sun)light, fertilizers, sugars, CO |
|---|---|
| MeSH term(s) | Microalgae/genetics ; Microalgae/metabolism ; Fertilizers ; Biotechnology ; Crops, Agricultural ; Biomass |
| Chemical Substances | Fertilizers |
| Language | English |
| Publishing date | 2023-01-25 |
| Publishing country | England |
| Document type | Journal Article ; Review |
| ZDB-ID | 47474-5 |
| ISSN | 1879-3096 ; 0167-7799 |
| ISSN (online) | 1879-3096 |
| ISSN | 0167-7799 |
| DOI | 10.1016/j.tibtech.2022.12.017 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 2750: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG) |
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.
2024 Volume 10, Issue 7, Page(s) e28723
Abstract: Electrical impedance spectroscopy (EIS) stands as a widely employed characterization technique for studying muscular tissue in both physio/pathological conditions. This methodology commonly involves modeling tissues through equivalent electrical circuits, ...
| Abstract | Electrical impedance spectroscopy (EIS) stands as a widely employed characterization technique for studying muscular tissue in both physio/pathological conditions. This methodology commonly involves modeling tissues through equivalent electrical circuits, facilitating a correlation between electrical parameters and physiological properties. Within existing literature, diverse equivalent electrical circuits have been proposed, varying in complexity and fitting properties. However, to date, none have definitively proven to be the most suiTable for tissue impedance measurements. This study aims to outline a systematic methodology for EIS measurements and to compare the performances of three widely used electrical circuits in characterizing both physiological and pathological muscle tissue conditions. Results highlight that, for optimal fitting with electrical parameters relevant to tissue characterization, the choice of the circuit to be fitted closely hinges on the specific measurement objectives, including measurement parameters and associated physiological features. Naturally, this necessitates a balance between simplicity and fitting accuracy. |
|---|---|
| Language | English |
| Publishing date | 2024-03-27 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 2835763-2 |
| ISSN | 2405-8440 |
| ISSN | 2405-8440 |
| DOI | 10.1016/j.heliyon.2024.e28723 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.
2023 Volume 22, Issue 1, Page(s) 12
Abstract: Microalgae are considered a suitable production platform for high-value lipids and oleochemicals. Several species including Nannochloropsis oceanica produce large amounts of essential [Formula: see text]-3 polyunsaturated fatty acids (PUFAs) which are ... ...
| Abstract | Microalgae are considered a suitable production platform for high-value lipids and oleochemicals. Several species including Nannochloropsis oceanica produce large amounts of essential [Formula: see text]-3 polyunsaturated fatty acids (PUFAs) which are integral components of food and feed and have been associated with health-promoting effects. N. oceanica can further accumulate high contents of non-polar lipids with chemical properties that render them a potential replacement for plant oils such as palm oil. However, biomass and lipid productivities obtained with microalgae need to be improved to reach commercial feasibility. Genetic engineering can improve biomass and lipid productivities, for instance by increasing carbon flux to lipids. Here, we report the overexpression of glycerol-3-phosphate acyltransferase (GPAT) in N. oceanica during favorable growth conditions as a strategy to increase non-polar lipid content. Transformants overproducing either an endogenous (NoGPAT) or a heterologous (Acutodesmus obliquus GPAT) GPAT enzyme targeted to the endoplasmic reticulum had up to 42% and 51% increased non-polar lipid contents, respectively, compared to the wild type. Biomass productivities of transformant strains were not substantially impaired, resulting in lipid productivities that were increased by up to 37% and 42% for NoGPAT and AoGPAT transformants, respectively. When exposed to nutrient stress, transformants and wild type had similar lipid contents, suggesting that GPAT enzyme exerts strong flux control on lipid synthesis in N. oceanica under favorable growth conditions. NoGPAT transformants further accumulated PUFAs in non-polar lipids, reaching a total of 6.8% PUFAs per biomass, an increase of 24% relative to the wild type. Overall, our results indicate that GPAT is an interesting target for engineering of lipid metabolism in microalgae, in order to improve non-polar lipid and PUFAs accumulation in microalgae. |
|---|---|
| MeSH term(s) | Glycerol/metabolism ; Oils/metabolism ; Genetic Engineering ; Glycerol-3-Phosphate O-Acyltransferase/genetics ; Glycerol-3-Phosphate O-Acyltransferase/metabolism ; Stramenopiles/genetics ; Microalgae/genetics ; Microalgae/metabolism ; Biomass ; Phosphates/metabolism |
| Chemical Substances | Glycerol (PDC6A3C0OX) ; Oils ; Glycerol-3-Phosphate O-Acyltransferase (EC 2.3.1.15) ; Phosphates |
| Language | English |
| Publishing date | 2023-01-16 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 2091377-1 |
| ISSN | 1475-2859 ; 1475-2859 |
| ISSN (online) | 1475-2859 |
| ISSN | 1475-2859 |
| DOI | 10.1186/s12934-022-01987-y |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.
2019
| Keywords | Life Science |
|---|---|
| Language | English |
| Publishing country | nl |
| Document type | Book ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
2018
| Keywords | Life Science |
|---|---|
| Language | English |
| Publishing country | nl |
| Document type | Book ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
Biotechnology advances. 2022 Jan., Feb., v. 54
2022
Abstract: Besides being considered pathogens, viruses are important drivers of evolution and they can shape large ecological and biogeochemical processes, by influencing host fitness, population dynamics, and community structures. Moreover, they are simple systems ...
| Abstract | Besides being considered pathogens, viruses are important drivers of evolution and they can shape large ecological and biogeochemical processes, by influencing host fitness, population dynamics, and community structures. Moreover, they are simple systems that can be used and manipulated to be beneficial and useful for biotechnological applications. In this context, microalgae biotechnology is a growing field of research, which investigated the usage of photosynthetic microorganisms for the sustainable production of food, fuel, chemical, and pharmaceutical sectors. Viruses infecting microalgae have become important subject of ecological studies related to marine and aquatic environments only four decades ago when virus-like-particles associated with bloom-forming algae were discovered. These first findings have opened new questions on evolution and identity. To date, 63 viruses that infect eukaryotic microalgae have been isolated and cultured. In this short review we briefly summarize what is known about viruses infecting eukaryotic microalgae, and how acknowledging their importance can shape future research focussed not only on marine ecology and evolutionary biology but also on biotechnological applications related to microalgae cell factories. |
|---|---|
| Keywords | biotechnology ; evolution ; marine science ; microalgae ; photosynthesis ; population dynamics |
| Language | English |
| Dates of publication | 2022-01 |
| Publishing place | Elsevier Inc. |
| Document type | Article |
| ZDB-ID | 47165-3 |
| ISSN | 0734-9750 |
| ISSN | 0734-9750 |
| DOI | 10.1016/j.biotechadv.2021.107790 |
| Database | NAL-Catalogue (AGRICOLA) |
| Zs.A 3730: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG) |
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.