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Article ; Online: 3D-printed patient-specific pelvis phantom for dosimetry measurements for prostate stereotactic radiotherapy with dominant intraprostatic lesion boost.

Giacometti, Valentina / King, Raymond B / McCreery, Craig / Buchanan, Fraser / Jeevanandam, Prakash / Jain, Suneil / Hounsell, Alan R / McGarry, Conor K

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

2021 Volume 92, Page(s) 8–14

Abstract: Aim: Developing and assessing the feasibility of using a three-dimensional (3D) printed patient-specific anthropomorphic pelvis phantom for dose calculation and verification for stereotactic ablative radiation therapy (SABR) with dose escalation to the ... ...

Abstract	Aim: Developing and assessing the feasibility of using a three-dimensional (3D) printed patient-specific anthropomorphic pelvis phantom for dose calculation and verification for stereotactic ablative radiation therapy (SABR) with dose escalation to the dominant intraprostatic lesions. Material and methods: A 3D-printed pelvis phantom, including bone-mimicking material, was fabricated based on the computed tomography (CT) images of a prostate cancer patient. To compare the extent to which patient and phantom body and bones overlapped, the similarity Dice coefficient was calculated. Modular cylindrical inserts were created to encapsulate radiochromic films and ionization chamber for absolute dosimetry measurements at the location of prostate and at the boost region. Gamma analysis evaluation with 2%/2mm criteria was performed to compare treatment planning system calculations and measured dose when delivering a 10 flattening filter free (FFF) SABR plan and a 10FFF boost SABR plan. Results: Dice coefficients of 0.98 and 0.91 were measured for body and bones, respectively, demonstrating agreement between patient and phantom outlines. For the boost plans the gamma analysis yielded 97.0% of pixels passing 2%/2mm criteria and these results were supported by the chamber average dose difference of 0.47 ± 0.03%. These results were further improved when overriding the bone relative electron density: 97.3% for the 2%/2mm gamma analysis, and 0.05 ± 0.03% for the ionization chamber average dose difference. Conclusions: The modular patient-specific 3D-printed pelvis phantom has proven to be a highly attractive and versatile tool to validate prostate SABR boost plans using multiple detectors.
Language	English
Publishing date	2021-11-22
Publishing country	Italy
Document type	Journal Article
ZDB-ID	1122650-x
ISSN	1724-191X ; 1120-1797
ISSN (online)	1724-191X
ISSN	1120-1797
DOI	10.1016/j.ejmp.2021.10.018
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Article ; Online: Impacts of residential indoor air quality and environmental risk factors on adult asthma-related health outcomes in Chicago, IL.

Kang, Insung / McCreery, Anna / Azimi, Parham / Gramigna, Amanda / Baca, Griselda / Hayes, Whitney / Crowder, Timothy / Scheu, Rachel / Evens, Anne / Stephens, Brent

Journal of exposure science & environmental epidemiology

2022 Volume 33, Issue 3, Page(s) 358–367

Abstract: Background: Residential environments are known to contribute to asthma.: Objective: To examine the joint impacts of exposures to residential indoor and outdoor air pollutants and housing risk factors on adult asthma-related health outcomes.: ... ...

Abstract	Background: Residential environments are known to contribute to asthma. Objective: To examine the joint impacts of exposures to residential indoor and outdoor air pollutants and housing risk factors on adult asthma-related health outcomes. Methods: We analyzed >1-year of data from 53 participants from 41 homes in the pre-intervention period of the Breathe Easy Project prior to ventilation and filtration retrofits. Health outcomes included surveys of asthma control, health-related quality of life, stress, and healthcare utilizations. Environmental assessments included quarterly measurements of indoor and outdoor pollutants (e.g., HCHO, CO, CO Results: Cross-sectional analyses using mixed-effects models indicated that lower annual average asthma control test (ACT) scores were associated (p < 0.05) with higher indoor NO Significance: Findings suggest that residential risk factors, including indoor air pollution (especially NO Impact: This study highlights the importance of residential indoor air quality and environmental risk factors for asthma control, health-related quality of life, and emergency department visits for asthma. Two timescales of mixed models suggest that exposure to indoor NO
MeSH term(s)	Adult ; Humans ; Air Pollution, Indoor/analysis ; Nitrogen Dioxide/adverse effects ; Nitrogen Dioxide/analysis ; Quality of Life ; Chicago ; Cross-Sectional Studies ; Environmental Exposure/adverse effects ; Environmental Exposure/analysis ; Air Pollution/analysis ; Air Pollutants/adverse effects ; Air Pollutants/analysis ; Asthma/epidemiology ; Asthma/chemically induced ; Particulate Matter/adverse effects ; Particulate Matter/analysis ; Risk Factors ; Outcome Assessment, Health Care
Chemical Substances	Nitrogen Dioxide (S7G510RUBH) ; Air Pollutants ; Particulate Matter
Language	English
Publishing date	2022-11-30
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2218551-3
ISSN	1559-064X ; 1559-0631
ISSN (online)	1559-064X
ISSN	1559-0631
DOI	10.1038/s41370-022-00503-z
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Article ; Online: Mild hearing loss is a developmental risk: Response to Carew and colleagues.

McCreery, R W / Walker, E A / Tomblin, J B / Oleson, J J / Ambrose, S A / Moeller, M P

Child: care, health and development

2018 Volume 44, Issue 6, Page(s) 926–927

MeSH term(s)	Hearing Loss ; Humans ; Severity of Illness Index
Language	English
Publishing date	2018-11-22
Publishing country	England
Document type	Letter ; Comment
ZDB-ID	223039-2
ISSN	1365-2214 ; 0305-1862
ISSN (online)	1365-2214
ISSN	0305-1862
DOI	10.1111/cch.12602
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Article ; Online: Indoor air quality impacts of residential mechanical ventilation system retrofits in existing homes in Chicago, IL.

Kang, Insung / McCreery, Anna / Azimi, Parham / Gramigna, Amanda / Baca, Griselda / Abromitis, Kari / Wang, Mingyu / Zeng, Yicheng / Scheu, Rachel / Crowder, Tim / Evens, Anne / Stephens, Brent

The Science of the total environment

2021 Volume 804, Page(s) 150129

Abstract: Mechanical ventilation systems are used in residences to introduce ventilation air and dilute indoor-generated pollutants. A variety of ventilation system types can be used in home retrofits, influencing indoor air quality (IAQ) in different ways. Here ... ...

Abstract	Mechanical ventilation systems are used in residences to introduce ventilation air and dilute indoor-generated pollutants. A variety of ventilation system types can be used in home retrofits, influencing indoor air quality (IAQ) in different ways. Here we describe the Breathe Easy Project, a >2-year longitudinal, pseudo-randomized, crossover study designed to assess IAQ and adult asthma outcomes before and after installing residential mechanical ventilation systems in 40 existing homes in Chicago, IL. Each home received one of three types of ventilation systems: continuous exhaust-only, intermittent powered central-fan-integrated-supply (CFIS), or continuous balanced system with an energy recovery ventilator (ERV). Homes with central heating and/or cooling systems also received MERV 10 filter replacements. Approximately weeklong field measurements were conducted at each home on a quarterly basis throughout the study to monitor environmental conditions, ventilation operation, and indoor and outdoor pollutants, including size-resolved particles (0.3-10 μm), ozone (O
MeSH term(s)	Adult ; Air Pollutants/analysis ; Air Pollution, Indoor/analysis ; Chicago ; Cross-Over Studies ; Humans ; Respiration, Artificial
Chemical Substances	Air Pollutants
Language	English
Publishing date	2021-09-08
Publishing country	Netherlands
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2021.150129
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Article ; Online: Stability of Audiometric Thresholds for Children with Hearing Aids Applying the American Academy of Audiology Pediatric Amplification Guideline: Implications for Safety.

McCreery, Ryan / Walker, Elizabeth / Spratford, Meredith / Kirby, Benjamin / Oleson, Jacob / Brennan, Marc

Journal of the American Academy of Audiology

2016 Volume 27, Issue 3, Page(s) 252–263

Abstract: Background: Children who wear hearing aids may be at risk for further damage to their hearing from overamplification. Previous research on amplification-induced hearing loss has included children using linear amplification or simulations of predicted ... ...

Abstract	Background: Children who wear hearing aids may be at risk for further damage to their hearing from overamplification. Previous research on amplification-induced hearing loss has included children using linear amplification or simulations of predicted threshold shifts based on nonlinear amplification formulae. A relationship between threshold shifts and the use of nonlinear hearing aids in children has not been empirically verified. Purpose: The purpose of the study was to compare predicted threshold shifts from amplification to longitudinal behavioral thresholds in a large group of children who wear hearing aids to determine the likelihood of amplification-induced hearing loss. Research design: An accelerated longitudinal design was used to collect behavioral threshold and amplification data prospectively. Study sample: Two-hundred and thirteen children with mild-to-profound hearing loss who wore hearing aids were included in the analysis. Data collection and analysis: Behavioral audiometric thresholds, hearing aid outputs, and hearing aid use data were collected for each participant across four study visits. Individual ear- and frequency-specific safety limits were derived based on the Modified Power Law to determine the level at which increased amplification could result in permanent threshold shifts. Behavioral thresholds were used to estimate which children would be above the safety limit at 500, 1000, 2000, and 4000 Hz using thresholds in dB HL and then in dB SPL in the ear canal. Changes in thresholds across visits were compared for children who were above and below the safety limits. Results: Behavioral thresholds decreased across study visits for all children, regardless of whether their amplification was above the safety limits. The magnitude of threshold change across time corresponded with changes in ear canal acoustics as measured by the real-ear-to-coupler difference. Conclusions: Predictions of threshold changes due to amplification for children with hearing loss did not correspond with observed changes in threshold over across 2-4 yr of monitoring amplification. Use of dB HL thresholds and predictions of hearing aid output to set the safety limit resulted in a larger number of children being classified as above the safety limit than when safety limits were based on dB SPL thresholds and measured hearing aid output. Children above the safety limit for the dB SPL criteria tended to be fit above prescriptive targets. Additional research should seek to explain how the Modified Power Law predictions of threshold shift overestimated risk for children who wear hearing aids.
MeSH term(s)	Academies and Institutes ; Audiology ; Audiometry ; Auditory Threshold ; Calibration ; Child ; Child, Preschool ; Hearing Aids/standards ; Hearing Loss/diagnosis ; Hearing Loss/etiology ; Hearing Tests ; Humans ; Longitudinal Studies ; Pediatrics ; Practice Guidelines as Topic ; United States
Language	English
Publishing date	2016-02-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	1132599-9
ISSN	2157-3107 ; 1050-0545
ISSN (online)	2157-3107
ISSN	1050-0545
DOI	10.3766/jaaa.15049
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Zs.A 3529: Show issues

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Article: Managing Cancer Care During the COVID-19 Pandemic: Agility and Collaboration Toward a Common Goal

Ueda, M. / Martins, R. / Hendrie, P. C. / McDonnell, T. / Crews, J. R. / Wong, T. L. / McCreery, B. / Jagels, B. / Crane, A. / Byrd, D. R. / Pergam, S. A. / Davidson, N. E. / Liu, C. / Stewart, F. M.

Journal of the National Comprehensive Cancer Network : JNCCN

Abstract: The first confirmed case of coronavirus disease 2019 (COVID-19) in the United States was reported on January 20, 2020, in Snohomish County, Washington At the epicenter of COVID-19 in the United States, the Seattle Cancer Care Alliance, Fred Hutchinson ... ...

Abstract	The first confirmed case of coronavirus disease 2019 (COVID-19) in the United States was reported on January 20, 2020, in Snohomish County, Washington At the epicenter of COVID-19 in the United States, the Seattle Cancer Care Alliance, Fred Hutchinson Cancer Research Center, and University of Washington are at the forefront of delivering care to patients with cancer during this public health crisis This Special Feature highlights the unique circumstances and challenges of cancer treatment amidst this global pandemic, and the importance of organizational structure, preparation, agility, and a shared vision for continuing to provide cancer treatment to patients in the face of uncertainty and rapid change
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #11181
Database	COVID19

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Article ; Online: Managing Cancer Care During the COVID-19 Pandemic: Agility and Collaboration Toward a Common Goal.

Ueda, Masumi / Martins, Renato / Hendrie, Paul C / McDonnell, Terry / Crews, Jennie R / Wong, Tracy L / McCreery, Brittany / Jagels, Barbara / Crane, Aaron / Byrd, David R / Pergam, Steven A / Davidson, Nancy E / Liu, Catherine / Stewart, F Marc

Journal of the National Comprehensive Cancer Network : JNCCN

2020 , Page(s) 1–4

Abstract: The first confirmed case of coronavirus disease 2019 (COVID-19) in the United States was reported on January 20, 2020, in Snohomish County, Washington. At the epicenter of COVID-19 in the United States, the Seattle Cancer Care Alliance, Fred Hutchinson ... ...

Abstract	The first confirmed case of coronavirus disease 2019 (COVID-19) in the United States was reported on January 20, 2020, in Snohomish County, Washington. At the epicenter of COVID-19 in the United States, the Seattle Cancer Care Alliance, Fred Hutchinson Cancer Research Center, and University of Washington are at the forefront of delivering care to patients with cancer during this public health crisis. This Special Feature highlights the unique circumstances and challenges of cancer treatment amidst this global pandemic, and the importance of organizational structure, preparation, agility, and a shared vision for continuing to provide cancer treatment to patients in the face of uncertainty and rapid change.
Keywords	covid19
Language	English
Publishing date	2020-03-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	2250759-0
ISSN	1540-1413 ; 1540-1405
ISSN (online)	1540-1413
ISSN	1540-1405
DOI	10.6004/jnccn.2020.7560
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Article ; Online: Listening effort and perceived clarity for normal-hearing children with the use of digital noise reduction.

Gustafson, Samantha / McCreery, Ryan / Hoover, Brenda / Kopun, Judy G / Stelmachowicz, Pat

Ear and hearing

2014 Volume 35, Issue 2, Page(s) 183–194

Abstract: Objectives: The goal of this study was to evaluate how digital noise reduction (DNR) impacts listening effort and judgment of sound clarity in children with normal hearing. It was hypothesized that when two DNR algorithms differing in signal-to-noise ... ...

Abstract	Objectives: The goal of this study was to evaluate how digital noise reduction (DNR) impacts listening effort and judgment of sound clarity in children with normal hearing. It was hypothesized that when two DNR algorithms differing in signal-to-noise ratio (SNR) output are compared, the algorithm that provides the greatest improvement in overall output SNR will reduce listening effort and receive a better clarity rating from child listeners. A secondary goal was to evaluate the relation between the inversion method measurements and listening effort with DNR processing. Design: Twenty-four children with normal hearing (ages 7 to 12 years) participated in a speech recognition task in which consonant-vowel-consonant nonwords were presented in broadband background noise. Test stimuli were recorded through two hearing aids with DNR off and DNR on at 0 dB and +5 dB input SNR. Stimuli were presented to listeners and verbal response time (VRT) and phoneme recognition scores were measured. The underlying assumption was that an increase in VRT reflects an increase in listening effort. Children rated the sound clarity for each condition. The two commercially available HAs were chosen based on: (1) an inversion technique, which was used to quantify the magnitude of change in SNR with the activation of DNR, and (2) a measure of magnitude-squared coherence, which was used to ensure that DNR in both devices preserved the spectrum. Results: One device provided a greater improvement in overall output SNR than the other. Both DNR algorithms resulted in minimal spectral distortion as measured using coherence. For both devices, VRT decreased for the DNR-on condition, suggesting that listening effort decreased with DNR in both devices. Clarity ratings were also better in the DNR-on condition for both devices. The device showing the greatest improvement in output SNR with DNR engaged improved phoneme recognition scores. The magnitude of this improved phoneme recognition was not accurately predicted with measurements of output SNR. Measured output SNR varied in the ability to predict other outcomes. Conclusions: Overall, results suggest that DNR effectively reduces listening effort and improves subjective clarity ratings in children with normal hearing but that these improvements are not necessarily related to the output SNR improvements or preserved speech spectra provided by the DNR.
MeSH term(s)	Algorithms ; Auditory Perception/physiology ; Child ; Female ; Healthy Volunteers ; Hearing Aids ; Humans ; Male ; Noise/prevention & control ; Signal-To-Noise Ratio ; Speech Perception/physiology
Language	English
Publishing date	2014-01-28
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	603093-2
ISSN	1538-4667 ; 0196-0202
ISSN (online)	1538-4667
ISSN	0196-0202
DOI	10.1097/01.aud.0000440715.85844.b8
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Article ; Online: PRIMA subretinal wireless photovoltaic microchip implantation in non-human primate and feline models.

Muqit, Mahiul M K / Hubschman, Jean Pierre / Picaud, Serge / McCreery, Douglas B / van Meurs, Jan C / Hornig, Ralf / Buc, Guillaume / Deterre, Martin / Nouvel-Jaillard, Céline / Bouillet, Elodie / Fovet, Claire-Maelle / Hantraye, Philippe / Sahel, José / Martel, Joseph N / Le Mer, Yannick

PloS one

2020 Volume 15, Issue 4, Page(s) e0230713

Abstract: Purpose: To evaluate the surgical technique for subretinal implantation of two sizes of PRIMA photovoltaic wireless microchip in two animal models, and refine these surgical procedures for human trials.: Methods: Cats and Macaca fascicularis primates ...

Abstract	Purpose: To evaluate the surgical technique for subretinal implantation of two sizes of PRIMA photovoltaic wireless microchip in two animal models, and refine these surgical procedures for human trials. Methods: Cats and Macaca fascicularis primates with healthy retina underwent vitrectomy surgery and were implanted with subretinal wireless photovoltaic microchip at the macula/central retina. The 1.5mm PRIMA chip was initially studied in feline eyes. PRIMA implant (2mm,1.5mm sizes) arrays were studied in primates. Feasibility of subretinal chip implantation was evaluated with a newly-developed surgical technique, with surgical complications and adverse events recorded. Results: The 1.5mm implant was placed in the central retina of 11 feline eyes, with implantation duration 43-106 days. The 1.5mm implant was correctly positioned into central macula of 11 primate eyes, with follow-up periods of minimum 6 weeks (n = 11), 2 years (n = 2), and one eye for 3 years. One primate eye underwent multi-chip 1.5mm implantation using two 1.5mm chips. The 2mm implant was delivered to 4 primate eyes. Optical coherence tomography confirmed correct surgical placement of photovoltaic arrays in the subretinal space in all 26 eyes. Intraoperative complications in primate eyes included retinal tear, macular hole, retinal detachment, and vitreous hemorrhage that resolved spontaneously. Postoperatively, there was no case of significant ocular inflammation in the 1.5mm implant group. Conclusions: We report subretinal implantation of 1.5mm and 2mm photovoltaic arrays in the central retina of feline and central macula of primate eyes with a low rate of device-related complications. The in vivo PRIMA implantation technique has been developed and refined for use for a 2mm PRIMA implant in ongoing human trials.
MeSH term(s)	Animals ; Cats ; Macaca fascicularis ; Microtechnology/instrumentation ; Prostheses and Implants ; Retina/surgery ; Safety ; Wireless Technology
Language	English
Publishing date	2020-04-08
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0230713
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Article ; Online: Electrical performance of penetrating microelectrodes chronically implanted in cat cortex.

Kane, Sheryl R / Cogan, Stuart F / Ehrlich, Julia / Plante, Timothy D / McCreery, Douglas B

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

2011 Volume 2011, Page(s) 5416–5419

Abstract: Penetrating multielectrode arrays with electrode coatings of sputtered iridium oxide (SIROF) have been implanted chronically in cat cortex for periods over 300 days. The ability of these electrodes to inject charge at levels above expected thresholds for ...

Abstract	Penetrating multielectrode arrays with electrode coatings of sputtered iridium oxide (SIROF) have been implanted chronically in cat cortex for periods over 300 days. The ability of these electrodes to inject charge at levels above expected thresholds for neural excitation has been examined in vivo by measurements of voltage transients in response to current-controlled, cathodal stimulation pulsing. The effect of current pulse width from 150 μs to 500 μs and voltage biasing of the electrodes in the interpulse period at two levels, 0.0 V and 0.6 V vs. Ag\|AgCl, were also investigated. The results of in vivo characterization of the electrodes by open-circuit potential measurements, cyclic voltammetry and impedance spectroscopy are also reported.
MeSH term(s)	Animals ; Biocompatible Materials/chemistry ; Cats ; Electric Impedance ; Electric Stimulation/instrumentation ; Electrodes, Implanted ; Electroencephalography/instrumentation ; Equipment Design ; Equipment Failure Analysis ; Iridium/chemistry ; Microelectrodes ; Motor Cortex/physiology ; Somatosensory Cortex/physiology
Chemical Substances	Biocompatible Materials ; Iridium (44448S9773)
Language	English
Publishing date	2011-12-15
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ISSN	2694-0604
ISSN (online)	2694-0604
DOI	10.1109/IEMBS.2011.6091339
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