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  1. Article ; Online: Doc, I Have COPD: Will I Tolerate Moderate-High Altitude?

    Domenighetti, Guido

    Respiration; international review of thoracic diseases

    2018  Volume 97, Issue 2, Page(s) 105–107

    MeSH term(s) Altitude ; Forced Expiratory Volume ; Humans ; Pulmonary Disease, Chronic Obstructive
    Language English
    Publishing date 2018-11-07
    Publishing country Switzerland
    Document type Editorial ; Comment
    ZDB-ID 206674-9
    ISSN 1423-0356 ; 0025-7931
    ISSN (online) 1423-0356
    ISSN 0025-7931
    DOI 10.1159/000493861
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Doc, I Have COPD: Will I Tolerate Moderate-High Altitude?

    Domenighetti, Guido

    Respiration

    2018  Volume 97, Issue 2, Page(s) 105–107

    Institution Department of Internal Medicine, Pneumology Unit, Regional Hospital, Locarno, Switzerland
    Language English
    Publishing date 2018-11-07
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Editorial Comment
    ZDB-ID 206674-9
    ISSN 1423-0356 ; 0025-7931
    ISSN (online) 1423-0356
    ISSN 0025-7931
    DOI 10.1159/000493861
    Database Karger publisher's database

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  3. Article: La dyspnée cachée ou la difficulté de diagnostiquer précocement une hypertension artérielee pulmonaire.

    Domenighetti, Guido

    Revue medicale suisse

    2013  Volume 9, Issue 371, Page(s) 225–226

    Title translation Hidden shortness of breath or the difficulty of early diagnosis of pulmonary hypertension.
    MeSH term(s) Delayed Diagnosis ; Dyspnea/etiology ; Early Diagnosis ; Humans ; Hypertension, Pulmonary/diagnosis
    Language French
    Publishing date 2013-01-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Prognosis, screening, early detection and differentiation of arterial pulmonary hypertension.

    Domenighetti, Guido

    Swiss medical weekly

    2007  Volume 137, Issue 23-24, Page(s) 331–336

    Abstract: Pulmonary hypertension (PH) has been partially reclassified during the 2003 Third World Symposium on Pulmonary Arterial Hypertension held in Venice. PH is a common disorder that may complicate a variety of cardiopulmonary diseases, including severe COPD, ...

    Abstract Pulmonary hypertension (PH) has been partially reclassified during the 2003 Third World Symposium on Pulmonary Arterial Hypertension held in Venice. PH is a common disorder that may complicate a variety of cardiopulmonary diseases, including severe COPD, left ventricular failure and chronic thromboembolic obstruction of the pulmonary arteries. Pulmonary arterial hypertension (PAH) is an increase in pulmonary arterial pressure which is not due to classical coexistent cardiopulmonary disease. PAH usually occurs in the absence of an evident cause (idiopathic or familial) or it may be associated with connective tissue disease, HIV infection, chronic liver disease, congenital systemic-to-pulmonary shunts, venous or capillary involvement, thyroid or myeloproliferative disorders as well as a result of the use of toxic agents and anorexigens. The actuality of developed disease-specific treatments over the past decade, emphasises the importance of an early screening and detection of PH which, even optimally treated in advanced stages, still remains a progressive lethal disease in most of its forms. Early identification represents a real challenge for the clinician: in fact, it is believed that an early recognition and, thus, an early treatment, might be associated with improved survival. In this review, after a short introduction on disease prognosis, we will focus on screening and early recognition of some categories of PH, based on a sequential approach that includes clinical suspicion, detection and differentiation of pulmonary hypertension. This strategy should consent to reach an assessment of severity, ultimately providing the best selective use of therapies.
    MeSH term(s) Diagnosis, Differential ; Early Diagnosis ; Humans ; Hypertension, Pulmonary/classification ; Hypertension, Pulmonary/diagnosis ; Mass Screening ; Prognosis ; Registries
    Language English
    Publishing date 2007-06-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2036179-8
    ISSN 1424-3997 ; 1424-7860
    ISSN (online) 1424-3997
    ISSN 1424-7860
    DOI 10.4414/smw.2007.11669
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Idiopathic pulmonary arterial hypertension and inhaled iloprost: good night rebound effects?

    Domenighetti, Guido M

    Respiration; international review of thoracic diseases

    2007  Volume 74, Issue 5, Page(s) 496–497

    MeSH term(s) Administration, Inhalation ; Half-Life ; Humans ; Hypertension, Pulmonary/drug therapy ; Iloprost/administration & dosage ; Vasodilator Agents/administration & dosage
    Chemical Substances Vasodilator Agents ; Iloprost (JED5K35YGL)
    Language English
    Publishing date 2007
    Publishing country Switzerland
    Document type Comment ; Editorial
    ZDB-ID 206674-9
    ISSN 1423-0356 ; 0025-7931
    ISSN (online) 1423-0356
    ISSN 0025-7931
    DOI 10.1159/000105538
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Prognosis, screening, early detection and differentiation of arterial pulmonary hypertension

    Domenighetti, Guido

    Swiss medical weekly

    2007  Volume 137, Issue 23/24, Page(s) 331

    Language German
    Document type Article
    ZDB-ID 2036179-8
    ISSN 1424-7860
    Database Current Contents Medicine

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  7. Article: Idiopathic Pulmonary Arterial Hypertension and Inhaled Iloprost: Good Night Rebound Effects?

    Domenighetti, Guido M.

    Respiration

    2007  Volume 74, Issue 5, Page(s) 496–497

    Institution Department of Intensive Care and Pneumology, Regional Hospital, Locarno, Switzerland
    Language English
    Publishing date 2007-03-27
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Editorial
    ZDB-ID 206674-9
    ISSN 1423-0356 ; 0025-7931
    ISSN (online) 1423-0356
    ISSN 0025-7931
    DOI 10.1159/000105538
    Database Karger publisher's database

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  8. Article: Pneumococcus pneumoniae infection and Guillain-Barré syndrome: fortuitous or specific association?

    Bianchi, Giorgia / Domenighetti, Guido

    Intensive care medicine

    2006  Volume 32, Issue 2, Page(s) 338–339

    MeSH term(s) Aged ; Diagnosis, Differential ; Guillain-Barre Syndrome/complications ; Guillain-Barre Syndrome/diagnosis ; Guillain-Barre Syndrome/immunology ; Humans ; Male ; Pneumonia, Pneumococcal/complications ; Pneumonia, Pneumococcal/diagnosis ; Pneumonia, Pneumococcal/immunology
    Language English
    Publishing date 2006-02
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0342-4642 ; 0340-0964 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0342-4642 ; 0340-0964 ; 0935-1701
    DOI 10.1007/s00134-005-0028-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Noninvasive ventilation for patients with acute lung injury or acute respiratory distress syndrome.

    Nava, Stefano / Schreiber, Ania / Domenighetti, Guido

    Respiratory care

    2011  Volume 56, Issue 10, Page(s) 1583–1588

    Abstract: Few studies have been performed on noninvasive ventilation (NIV) to treat hypoxic acute respiratory failure in patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). The outcomes of these patients, for whom endotracheal ... ...

    Abstract Few studies have been performed on noninvasive ventilation (NIV) to treat hypoxic acute respiratory failure in patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). The outcomes of these patients, for whom endotracheal intubation is not mandatory, depend on the degree of hypoxia, the presence of comorbidities and complications, and their illness severity. The use of NIV as an alternative to invasive ventilation in severely hypoxemic patients with ARDS (ie, P(aO(2))/F(IO(2)) < 200) is not generally advisable and should be limited to hemodynamically stable patients who can be closely monitored in an intensive care unit by highly skilled staff. Early NIV application may be extremely helpful in immunocompromised patients with pulmonary infiltrates, in whom intubation dramatically increases the risk of infection, pneumonia, and death. The use of NIV in patients with severe acute respiratory syndrome and other airborne diseases has generated debate, despite encouraging clinical results, mainly because of safety issues. Overall, the high rate of NIV failure suggests a cautious approach to NIV use in patients with ALI/ARDS, including early initiation, intensive monitoring, and prompt intubation if signs of NIV failure emerge.
    MeSH term(s) Acute Lung Injury/therapy ; Adult ; Critical Illness ; Humans ; Immunocompromised Host ; Intubation, Intratracheal ; Respiration, Artificial/methods ; Respiratory Distress Syndrome, Adult/therapy ; Treatment Outcome
    Keywords covid19
    Language English
    Publishing date 2011-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 603252-7
    ISSN 0020-1324 ; 0098-9142
    ISSN 0020-1324 ; 0098-9142
    DOI 10.4187/respcare.01209
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Adverse event reporting in adult intensive care units and the impact of a multifaceted intervention on drug-related adverse events.

    Pagnamenta, Alberto / Rabito, Giovanni / Arosio, Alessandra / Perren, Andreas / Malacrida, Roberto / Barazzoni, Fabrizio / Domenighetti, Guido

    Annals of intensive care

    2012  Volume 2, Issue 1, Page(s) 47

    Language English
    Publishing date 2012-11-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2617094-2
    ISSN 2110-5820 ; 2110-5820
    ISSN (online) 2110-5820
    ISSN 2110-5820
    DOI 10.1186/2110-5820-2-47
    Database MEDical Literature Analysis and Retrieval System OnLINE

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