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Article ; Online: Urogynecology digest.

Walsh, Caroline E

International urogynecology journal

2015 Volume 26, Issue 9, Page(s) 1391–1392

Language	English
Publishing date	2015-09
Publishing country	England
Document type	Journal Article
ISSN	1433-3023
ISSN (online)	1433-3023
DOI	10.1007/s00192-015-2716-7
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Article ; Online: Reduced dorsal fronto-striatal connectivity at rest in anorexia nervosa.

Muratore, Alexandra F / Foerde, Karin / Lloyd, E Caitlin / Touzeau, Caroline / Uniacke, Blair / Aw, Natalie / Semanek, David / Wang, Yun / Walsh, B Timothy / Attia, Evelyn / Posner, Jonathan / Steinglass, Joanna E

Psychological medicine

2024 , Page(s) 1–10

Abstract: Background: Anorexia nervosa (AN) is a serious psychiatric illness that remains difficult to treat. Elucidating the neural mechanisms of AN is necessary to identify novel treatment targets and improve outcomes. A growing body of literature points to a ... ...

Abstract	Background: Anorexia nervosa (AN) is a serious psychiatric illness that remains difficult to treat. Elucidating the neural mechanisms of AN is necessary to identify novel treatment targets and improve outcomes. A growing body of literature points to a role for dorsal fronto-striatal circuitry in the pathophysiology of AN, with increasing evidence of abnormal task-based fMRI activation within this network among patients with AN. Whether these abnormalities are present at rest and reflect fundamental differences in brain organization is unclear. Methods: The current study combined resting-state fMRI data from patients with AN ( Results: Compared to HC, patients showed significantly reduced right, but not left, anterior caudate-dlPFC connectivity ( Conclusions: Decreased coupling of dorsal fronto-striatal regions indicates that circuit-based abnormalities persist at rest and suggests this network may be a potential treatment target.
Language	English
Publishing date	2024-03-18
Publishing country	England
Document type	Journal Article
ZDB-ID	217420-0
ISSN	1469-8978 ; 0033-2917
ISSN (online)	1469-8978
ISSN	0033-2917
DOI	10.1017/S003329172400031X
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Article ; Online: Change in food choice during acute treatment and the effect on longer-term outcome in patients with anorexia nervosa.

Steinglass, Joanna E / Fei, Wenbo / Foerde, Karin / Touzeau, Caroline / Ruggiero, Julia / Lloyd, Caitlin / Attia, Evelyn / Wang, Yuanjia / Walsh, B Timothy

Psychological medicine

2023 Volume 54, Issue 6, Page(s) 1133–1141

Abstract: Background: Restriction of food intake is a central pathological feature of anorexia nervosa (AN). Maladaptive eating behavior and, specifically, limited intake of calorie-dense foods are resistant to change and contribute to poor long-term outcomes. ... ...

Abstract	Background: Restriction of food intake is a central pathological feature of anorexia nervosa (AN). Maladaptive eating behavior and, specifically, limited intake of calorie-dense foods are resistant to change and contribute to poor long-term outcomes. This study is a preliminary examination of whether change in food choices during inpatient treatment is related to longer-term clinical course. Methods: Individuals with AN completed a computerized Food Choice Task at the beginning and end of inpatient treatment to determine changes in high-fat and self-controlled food choices. Linear regression and longitudinal analyses tested whether change in task behavior predicted short-term outcome (body mass index [BMI] at discharge) and longer-term outcome (BMI and eating disorder psychopathology). Results: Among 88 patients with AN, BMI improved significantly with hospital treatment ( Conclusions: Short-term treatment is associated with improvement in BMI but with no significant change, on average, in choices made in a task known to predict actual eating. However, the degree to which individuals increased high-fat choices during treatment and decreased the use of self-control over food choice were associated with reduced weight loss over the following 3 years, underscoring the need to focus on changing eating behavior in treatment of AN.
MeSH term(s)	Humans ; Anorexia Nervosa/therapy ; Anorexia Nervosa/diagnosis ; Body Mass Index ; Food Preferences ; Feeding and Eating Disorders ; Hospitalization ; Treatment Outcome
Language	English
Publishing date	2023-10-02
Publishing country	England
Document type	Journal Article
ZDB-ID	217420-0
ISSN	1469-8978 ; 0033-2917
ISSN (online)	1469-8978
ISSN	0033-2917
DOI	10.1017/S0033291723002933
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Article ; Online: Longitudinal Medication Adherence in Older Adults With Multimorbidity and Association With Health Care Utilization: Results From the Irish Longitudinal Study on Ageing.

Walsh, Caroline A / Cahir, Caitriona / Bennett, Kathleen E

The Annals of pharmacotherapy

2020 Volume 55, Issue 1, Page(s) 5–14

Abstract: Background: The association between objectively measured nonadherence and health care utilization in multimorbid older people is unclear.: Objective: To measure medication adherence across multiple chronic conditions, identify adherence patterns, and ...

Abstract	Background: The association between objectively measured nonadherence and health care utilization in multimorbid older people is unclear. Objective: To measure medication adherence across multiple chronic conditions, identify adherence patterns, and estimate the association between adherence and self-reported health care utilization. Methods: This is a retrospective cohort study of multimorbid participants aged ≥70 years in the Irish LongituDinal Study on Ageing (TILDA). Eligible participants had linked pharmacy claims data and completed TILDA wave 2 (2 years after wave 1). The RxRisk-V tool was used to identify multimorbidity. Average adherence (AA) across RxRisk-V conditions was estimated using the CMA7 function (AdhereR). Group-based trajectory models (GBTMs) identified adherence patterns in the 12 months following wave 1. Negative binomial regression was used to estimate the association between adherence and the rate of subsequent self-reported general practitioner [GP] visits, emergency department (ED) visits, outpatient visits, and hospitalizations in the 12 months following adherence measurement (reported at wave 2). Adjusted Incident Rate Ratios (aIRR) and 95% CIs are presented. Results: Higher AA (CMA7) was associated with a small significant decrease in GP visit rate (aIRR = 0.70; CI = 0.53-0.94) and outpatient visit rate (aIRR = 0.44; CI = 0.23-0.81). GBTM identified 6 adherence groups (n = 1050). Compared with high adherers, group 1 (rapid decline, modest increase) membership (aIRR = 1.72; CI = 1.09-2.73) and group 4 (high adherence, delayed decline) membership (aIRR = 1.92; CI = 1.19-3.05) significantly increased ED visit rate. Conclusion and relevance: Suboptimal medication adherence in multimorbid older adults is associated with increased health care utilization. Identification of suboptimal adherence groups for medication management interventions may help decrease the health system burden and health care costs.
MeSH term(s)	Aged ; Aged, 80 and over ; Aging/psychology ; Emergency Service, Hospital/statistics & numerical data ; Emergency Service, Hospital/trends ; Female ; Health Care Costs ; Hospitalization/statistics & numerical data ; Hospitalization/trends ; Humans ; Ireland ; Longitudinal Studies ; Male ; Medication Adherence/statistics & numerical data ; Middle Aged ; Multimorbidity ; Patient Acceptance of Health Care/statistics & numerical data ; Retrospective Studies ; Self Report
Language	English
Publishing date	2020-07-01
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1101370-9
ISSN	1542-6270 ; 1060-0280
ISSN (online)	1542-6270
ISSN	1060-0280
DOI	10.1177/1060028020937996
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Article ; Online: Impacts of COVID-19 on caregivers of childhood cancer survivors.

Wimberly, Courtney E / Towry, Lisa / Caudill, Caroline / Johnston, Emily E / Walsh, Kyle M

Pediatric blood & cancer

2021 Volume 68, Issue 4, Page(s) e28943

Abstract: Purpose: We sought to assess the impact of disruptions due to coronavirus disease 2019 (COVID-19) on caregivers of childhood cancer survivors.: Methods: A 13-question survey containing multiple-choice, Likert-type, and free-text questions on ... ...

Abstract	Purpose: We sought to assess the impact of disruptions due to coronavirus disease 2019 (COVID-19) on caregivers of childhood cancer survivors. Methods: A 13-question survey containing multiple-choice, Likert-type, and free-text questions on experiences, behaviors, and attitudes during the COVID-19 outbreak was sent to childhood cancer caregivers and completed between April 13 and May 17, 2020. Ordered logistic regression was used to investigate relationships between demographics, COVID-related experiences, and caregiver well-being. Results: Caregivers from 321 unique families completed the survey, including 175 with children under active surveillance/follow-up care and 146 with children no longer receiving oncology care. Overall, caregivers expressed exceptional resiliency, highlighting commonalities between caring for a child with cancer and adopting COVID-19 prophylactic measures. However, respondents reported delayed/canceled appointments (50%) and delayed/canceled imaging (19%). Eleven percent of caregivers reported struggling to pay for basic needs, which was associated with greater disruption to daily life, greater feelings of anxiety, poorer sleep, and less access to social support (p < .05). Caregivers who were self-isolating reported greater feelings of anxiety and poorer sleep (p < .05). Respondents who expressed confidence in the government response to COVID-19 reported less disruption to their daily life, decreased feelings of depression and anxiety, better sleep, and greater hopefulness (p < .001) CONCLUSIONS: Caregivers are experiencing changes to medical care, financial disruptions, and emotional distress due to COVID-19. To better serve caregivers and medically at-risk children, clinicians must evaluate financial toxicity and feelings of isolation in families affected by childhood cancer, and work to provide reliable information on how COVID-19 may differentially impact their children.
MeSH term(s)	Adaptation, Psychological ; Adult ; Anxiety/psychology ; COVID-19/psychology ; Cancer Survivors/psychology ; Caregivers/psychology ; Child ; Female ; Humans ; Male ; Neoplasms/nursing ; Neoplasms/psychology ; Parent-Child Relations ; Parents/psychology ; Social Support ; Stress, Psychological/psychology
Language	English
Publishing date	2021-02-09
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2131448-2
ISSN	1545-5017 ; 1545-5009
ISSN (online)	1545-5017
ISSN	1545-5009
DOI	10.1002/pbc.28943
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Article ; Online: Progranulin regulates neurogenesis in the developing vertebrate retina.

Walsh, Caroline E / Hitchcock, Peter F

Developmental neurobiology

2017 Volume 77, Issue 9, Page(s) 1114–1129

Abstract: We evaluated the expression and function of the microglia-specific growth factor, Progranulin-a (Pgrn-a) during developmental neurogenesis in the embryonic retina of zebrafish. At 24 hpf pgrn-a is expressed throughout the forebrain, but by 48 hpf pgrn-a ... ...

Abstract	We evaluated the expression and function of the microglia-specific growth factor, Progranulin-a (Pgrn-a) during developmental neurogenesis in the embryonic retina of zebrafish. At 24 hpf pgrn-a is expressed throughout the forebrain, but by 48 hpf pgrn-a is exclusively expressed by microglia and/or microglial precursors within the brain and retina. Knockdown of Pgrn-a does not alter the onset of neurogenic programs or increase cell death, however, in its absence, neurogenesis is significantly delayed-retinal progenitors fail to exit the cell cycle at the appropriate developmental time and postmitotic cells do not acquire markers of terminal differentiation, and microglial precursors do not colonize the retina. Given the link between Progranulin and cell cycle regulation in peripheral tissues and transformed cells, we analyzed cell cycle kinetics among retinal progenitors following Pgrn-a knockdown. Depleting Pgrn-a results in a significant lengthening of the cell cycle. These data suggest that Pgrn-a plays a dual role during nervous system development by governing the rate at which progenitors progress through the cell cycle and attracting microglial progenitors into the embryonic brain and retina. Collectively, these data show that Pgrn-a governs neurogenesis by regulating cell cycle kinetics and the transition from proliferation to cell cycle exit and differentiation. © 2017 The Authors. Developmental Neurobiology Published by Wiley Periodicals, Inc. Develop Neurobiol 77: 1114-1129, 2017.
MeSH term(s)	Analysis of Variance ; Animals ; Bromodeoxyuridine/metabolism ; Cell Cycle/drug effects ; Cell Cycle/physiology ; Cell Differentiation/drug effects ; Cell Differentiation/physiology ; Cell Proliferation/drug effects ; Cell Proliferation/physiology ; Cyclin-Dependent Kinase Inhibitor p27/metabolism ; Cyclin-Dependent Kinase Inhibitor p57/metabolism ; Cyclins/metabolism ; Embryo, Nonmammalian ; Gene Expression Regulation, Developmental/drug effects ; Gene Expression Regulation, Developmental/genetics ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Humans ; Intercellular Signaling Peptides and Proteins/genetics ; Intercellular Signaling Peptides and Proteins/metabolism ; Microglia/drug effects ; Neurogenesis/drug effects ; Neurogenesis/genetics ; Neurogenesis/physiology ; Oligonucleotides, Antisense/pharmacology ; Retina/cytology ; Retina/embryology ; Retina/metabolism ; Zebrafish ; Zebrafish Proteins/genetics ; Zebrafish Proteins/metabolism
Chemical Substances	Cyclin-Dependent Kinase Inhibitor p57 ; Cyclins ; Intercellular Signaling Peptides and Proteins ; Oligonucleotides, Antisense ; Zebrafish Proteins ; progranulin A, zebrafish ; Green Fluorescent Proteins (147336-22-9) ; Cyclin-Dependent Kinase Inhibitor p27 (147604-94-2) ; Bromodeoxyuridine (G34N38R2N1)
Language	English
Publishing date	2017-05-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	2256184-5
ISSN	1932-846X ; 1097-4695 ; 1932-8451 ; 0022-3034
ISSN (online)	1932-846X ; 1097-4695
ISSN	1932-8451 ; 0022-3034
DOI	10.1002/dneu.22499
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Zs.A 853: Show issues

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Article ; Online: Identifying Adherence Patterns Across Multiple Medications and Their Association With Health Outcomes in Older Community-Dwelling Adults With Multimorbidity.

Walsh, Caroline A / Bennett, Kathleen E / Wallace, Emma / Cahir, Caitriona

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

2020 Volume 23, Issue 8, Page(s) 1063–1071

Abstract: Objectives: To classify older people with multimorbidity according to their adherence patterns and to examine the association between medication adherence and health outcomes.: Methods: This is a secondary analysis of a cohort study. Community- ... ...

Abstract	Objectives: To classify older people with multimorbidity according to their adherence patterns and to examine the association between medication adherence and health outcomes. Methods: This is a secondary analysis of a cohort study. Community-dwelling adults aged ≥70 years were recruited from 15 general practices in Ireland in 2010 (wave 1) and followed up 2 years later (wave 2). Participants had ≥2 RxRisk-V multimorbidity conditions at wave 1 and had ≥2 dispensations of RxRisk-V medications (wave 1-wave 2). Average adherence across RxRisk-V conditions was estimated based on continuous multiple-interval measure of medication availability (CMA7 function in AdhereR). Group-based trajectory models were used to group participants' adherence patterns for RxRisk-V medications. Multilevel regression was used to examine the association between adherence and (1) EuroQol 5-dimension (EQ-5D) utility (linear) and (2) vulnerability, using the Vulnerable Elders Survey (≥3 defined as vulnerable; logistic) at wave 2, controlling for potential confounders. Results: Average adherence (CMA7) was 77% across 501 participants. Group-based trajectory models identified 5 adherence groups: (1) initial low adherers, gradual increase; (2) high adherers, sharp decline; (3) steady adherers, gradual decline; (4) consistent high adherers; and (5) consistent nonadherers. Higher average adherence was associated with a significant increase in EQ-5D utility (adjusted β = 0.11, robust standard error 0.04). Group 5 was associated with significantly increased vulnerability compared to group 4 (adjusted odds ratio = 1.88; 95% confidence interval 1.01-3.50). Conclusion: Increased average adherence was associated with higher EQ-5D utility. Adherence grouping did not significantly impact utility. Suboptimal adherence to multiple medications in older adults with multimorbidity was associated with vulnerability.
MeSH term(s)	Aged ; Aged, 80 and over ; Female ; Geriatric Assessment/methods ; Health Status ; Humans ; Ireland/epidemiology ; Male ; Medication Adherence/statistics & numerical data ; Multimorbidity ; Polypharmacy ; Quality of Life
Language	English
Publishing date	2020-07-22
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1471745-1
ISSN	1524-4733 ; 1098-3015
ISSN (online)	1524-4733
ISSN	1098-3015
DOI	10.1016/j.jval.2020.03.016
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Article ; Online: Association between adherence to antihypertensive medications and health outcomes in middle and older aged community dwelling adults; results from the Irish longitudinal study on ageing.

Walsh, Caroline A / Cahir, Caitriona / Bennett, Kathleen E

European journal of clinical pharmacology

2019 Volume 75, Issue 9, Page(s) 1283–1292

Abstract: Purpose: To examine the association between antihypertensive medication (AHTM) implementation adherence and healthcare utilisation in community-dwelling adults aged ≥ 50 years in Ireland.: Methods: This was a prospective cohort study. The Irish ... ...

Abstract	Purpose: To examine the association between antihypertensive medication (AHTM) implementation adherence and healthcare utilisation in community-dwelling adults aged ≥ 50 years in Ireland. Methods: This was a prospective cohort study. The Irish Longitudinal Study on Ageing (TILDA) was linked to pharmacy claims data for participants aged ≥ 50 years. Participants were included if they had ≥ 3 pharmacy claims for one or more AHTM (ATC codes 'C02', 'C03', 'C07', 'C08' or 'C09') within the year preceding the year of self-reported healthcare utilisation outcome occurrence. Outcomes included self-reported general practitioner (GP), emergency department (ED), outpatient department visits and hospital admissions. Implementation adherence was measured using proportion of days covered (PDC), with participants classified as adherent if the average PDC ≥ 0.8. Negative binomial models were used to analyse the association between AHTM adherence and number of GP, ED, outpatient visits and hospitalisations (adjusted IRR and 95% CI are presented). Results: One thousand four hundred thirty-one participants were included. The majority of participants (72.6%) were considered adherent. Good implementation adherence to AHTM was associated with a significant decrease in self-reported GP visits (adjusted IRR 0.91, 95% CI 0.83-0.99). Adherence had no significant impact on the number of ED visits, outpatient visits or hospitalisations reported by TILDA participants. Conclusions: Good adherence to AHTM was associated with less self-reported GP visits in this population, suggesting improved overall health status. However, the impact of medication non-adherence on the other self-reported healthcare utilisation outcomes (ED, outpatient visits and hospitalisations) was not evident in this study.
MeSH term(s)	Aged ; Ambulatory Care/statistics & numerical data ; Antihypertensive Agents/therapeutic use ; Emergency Service, Hospital/statistics & numerical data ; Female ; Health Status ; Hospitalization/statistics & numerical data ; Humans ; Hypertension/drug therapy ; Hypertension/epidemiology ; Independent Living/statistics & numerical data ; Ireland/epidemiology ; Male ; Medication Adherence/statistics & numerical data ; Middle Aged ; Prospective Studies
Chemical Substances	Antihypertensive Agents
Language	English
Publishing date	2019-06-12
Publishing country	Germany
Document type	Journal Article
ZDB-ID	121960-1
ISSN	1432-1041 ; 0031-6970
ISSN (online)	1432-1041
ISSN	0031-6970
DOI	10.1007/s00228-019-02699-w
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Article ; Online: Prevalence and Factors Associated with Potential Drug-Drug Interactions in Older Community-Dwelling Adults: A Prospective Cohort Study.

Hughes, John E / Russo, Veronica / Walsh, Caroline / Menditto, Enrica / Bennett, Kathleen / Cahir, Caitriona

Drugs & aging

2021 Volume 38, Issue 11, Page(s) 1025–1037

Abstract: Background: Older patients are at increased risk of drug-drug interactions (DDIs) due to polypharmacy. Cardiovascular and central nervous system (CNS) drugs are commonly implicated in serious DDIs.: Objectives: This study aimed to determine the ... ...

Abstract	Background: Older patients are at increased risk of drug-drug interactions (DDIs) due to polypharmacy. Cardiovascular and central nervous system (CNS) drugs are commonly implicated in serious DDIs. Objectives: This study aimed to determine the prevalence and factors associated with potential 'severe' cardiovascular and CNS DDIs among older (≥ 70 years) community-dwellers. Methods: This was a prospective cohort study using linked data from a national pharmacy claims database and waves 1 and 2 of The Irish LongituDinal study on Ageing (TILDA). 'Severe' cardiovascular and CNS DDIs were identified using the British National Formulary 77 and Stockley's Drug Interactions. The prevalence of 'severe' DDIs (any DDI vs. none) was calculated. Logistic regression was used to examine the association between sociodemographic, functional ability, and medication-related factors and the risk of DDI exposure between waves 1 and 2. Results: A total of 1466 patients were included [mean age (standard deviation) = 78 (5.5) years; female n = 795, 54.2%]. In total, 332 community-dwellers aged ≥ 70 years [22.65%, 95% confidence interval (CI) 20.58-24.86] were potentially exposed to at least one 'severe' cardiovascular or CNS DDI, with more than half (54.82%) of this cohort dispensed the same DDI for a prolonged time (≥ 3 consecutive claims). Aspirin-warfarin was the most frequently dispensed (co-prescribed) DDI (n = 34, 10.24%, 95% CI 7.39-14.00), followed by atorvastatin-clarithromycin (n = 19, 5.72%, 95% CI 3.64-8.81). Polypharmacy [≥ 10 vs. < 5 drugs, odds ratio (OR) 13.40, 95% CI 8.22-21.85] and depression (depressed vs. not, OR 2.12, 95% CI 1.34-3.34) were significantly associated with these DDIs, after multivariable adjustment. Conclusion: 'Severe' cardiovascular and CNS DDIs are prevalent in older community-dwellers in Ireland, and those with polypharmacy and depression are at a significantly increased risk.
MeSH term(s)	Aged ; Cohort Studies ; Drug Interactions ; Female ; Humans ; Independent Living ; Longitudinal Studies ; Male ; Polypharmacy ; Prevalence ; Prospective Studies
Language	English
Publishing date	2021-10-11
Publishing country	New Zealand
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1075770-3
ISSN	1179-1969 ; 1170-229X
ISSN (online)	1179-1969
ISSN	1170-229X
DOI	10.1007/s40266-021-00898-8
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Article ; Online: An extension minimal important difference credibility item addressing construct proximity is a reliable alternative to the correlation item.

Wang, Yuting / Devji, Tahira / Carrasco-Labra, Alonso / Qasim, Anila / Hao, Qiukui / Kum, Elena / Devasenapathy, Niveditha / King, Madeleine T / Terluin, Berend / Terwee, Caroline B / Walsh, Michael / Furukawa, Toshi A / Tsujimoto, Yasushi / Guyatt, Gordon H

Journal of clinical epidemiology

2023 Volume 157, Page(s) 46–52

Abstract: ... item-a subjective assessment of similarity of the constructs (i.e., construct proximity) between PROM ...

Abstract	Objectives: Minimal important difference (MID), the smallest change or difference that patients perceive as important, aids interpretation of change in patient-reported outcome measure (PROM) scores. A credibility instrument that assesses the methodological rigor of an anchor-based MID includes one core item addressing the correlation between the PROM and the anchor. However, the majority of MID studies in the literature fail to report the correlation. To address this issue, we extended the anchor-based MID credibility instrument by adding an item addressing construct proximity as an alternative to the correlation item. Study design and setting: Informed by an MID methodological survey, we added an alternative item-a subjective assessment of similarity of the constructs (i.e., construct proximity) between PROM and anchor-to the correlation item and generated principles for the assessment. We sampled 101 MIDs and analyzed the assessments performed by each pair of raters. By calculating weighted Cohen's kappa, we assessed the reliability of the assessments. Results: Construct proximity assessment is based on the anticipated association between the anchor and PROM constructs: the closer the anticipated association, the higher the rating. Our detailed principles address the most frequently used anchors: transition ratings, measures of satisfaction, other PROMs, and clinical measures. The assessments showed acceptable agreement (weighted kappa 0.74, 95% CI 0.55-0.94) between raters. Conclusion: In the absence of a reported correlation coefficient, construct proximity assessment provides a useful alternative in the credibility assessment of anchor-based MID estimates.
MeSH term(s)	Humans ; Quality of Life ; Reproducibility of Results ; Surveys and Questionnaires ; Patient Reported Outcome Measures
Language	English
Publishing date	2023-03-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	639306-8
ISSN	1878-5921 ; 0895-4356
ISSN (online)	1878-5921
ISSN	0895-4356
DOI	10.1016/j.jclinepi.2023.03.001
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