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  1. Article ; Online: Contrasting Objective and Perceived Risk: Predicting COVID-19 Health Behaviors in a Nationally Representative U.S. Sample.

    Thompson, Rebecca R / Jones, Nickolas M / Garfin, Dana Rose / Holman, E Alison / Silver, Roxane Cohen

    Annals of behavioral medicine : a publication of the Society of Behavioral Medicine

    2024  Volume 58, Issue 4, Page(s) 242–252

    Abstract: ... 514 U.S. residents reported both their subjective risk perceptions (e.g., perceived likelihood ... of illness or death) and objective risk indices (e.g., age, weight, pre-existing conditions) of COVID-19 ...

    Abstract Background: Individuals confronting health threats may display an optimistic bias such that judgments of their risk for illness or death are unrealistically positive given their objective circumstances.
    Purpose: We explored optimistic bias for health risks using k-means clustering in the context of COVID-19. We identified risk profiles using subjective and objective indicators of severity and susceptibility risk for COVID-19.
    Methods: Between 3/18/2020-4/18/2020, a national probability sample of 6,514 U.S. residents reported both their subjective risk perceptions (e.g., perceived likelihood of illness or death) and objective risk indices (e.g., age, weight, pre-existing conditions) of COVID-19-related susceptibility and severity, alongside other pandemic-related experiences. Six months later, a subsample (N = 5,661) completed a follow-up survey with questions about their frequency of engagement in recommended health protective behaviors (social distancing, mask wearing, risk behaviors, vaccination intentions).
    Results: The k-means clustering procedure identified five risk profiles in the Wave 1 sample; two of these demonstrated aspects of optimistic bias, representing almost 44% of the sample. In OLS regression models predicting health protective behavior adoption at Wave 2, clusters representing individuals with high perceived severity risk were most likely to report engagement in social distancing, but many individuals who were objectively at high risk for illness and death did not report engaging in self-protective behaviors.
    Conclusions: Objective risk of disease severity only inconsistently predicted health protective behavior. Risk profiles may help identify groups that need more targeted interventions to increase their support for public health policy and health enhancing recommendations more broadly.
    MeSH term(s) Humans ; COVID-19/epidemiology ; Health Behavior ; Pandemics ; Surveys and Questionnaires
    Language English
    Publishing date 2024-02-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 632630-4
    ISSN 1532-4796 ; 0883-6612
    ISSN (online) 1532-4796
    ISSN 0883-6612
    DOI 10.1093/abm/kaad055
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Idiosyncratic media exposures during a pandemic and their link to well-being, cognition, and behavior over time.

    Jones, Nickolas M / Thompson, Rebecca R / Holman, E Alison / Silver, Roxane Cohen

    Proceedings of the National Academy of Sciences of the United States of America

    2023  Volume 120, Issue 26, Page(s) e2304550120

    Abstract: ... at the onset of the COVID-19 pandemic to identify a) distinct patterns of information-channel use (i.e ... associations of these information channel dimensions with distress (i.e., worry, global distress, and emotional ... exhaustion), cognition (e.g., beliefs about the seriousness of COVID-19, response efficacy, and dismissive ...

    Abstract Over the past two decades of research, increased media consumption in the context of collective traumas has been cross-sectionally and longitudinally linked to negative psychological outcomes. However, little is known about the specific information channels that may drive these patterns of response. The current longitudinal investigation uses a probability-based sample of 5,661 Americans measured at the onset of the COVID-19 pandemic to identify a) distinct patterns of information-channel use (i.e., dimensions) for COVID-related information, b) demographic correlates of these patterns, and c) prospective associations of these information channel dimensions with distress (i.e., worry, global distress, and emotional exhaustion), cognition (e.g., beliefs about the seriousness of COVID-19, response efficacy, and dismissive attitudes), and behavior (e.g., engaging in health-protective behaviors and risk-taking behaviors) 6 mo later. Four distinct information-channel dimensions emerged: journalistic complexity; ideologically focused news; domestically focused news; and nonnews. Results indicate that journalistic complexity was prospectively associated with more emotional exhaustion, belief in the seriousness of the coronavirus, response efficacy, engaging in health-protective behaviors, and less dismissiveness of the pandemic. A reliance on conservative-leaning media was prospectively associated with less psychological distress, taking the pandemic less seriously, and engaging in more risk-taking behaviors. We discuss the implications of this work for the public, policy makers, and future research.
    MeSH term(s) Humans ; United States ; COVID-19/epidemiology ; COVID-19/psychology ; Pandemics ; SARS-CoV-2 ; Health Behavior ; Cognition
    Language English
    Publishing date 2023-06-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2304550120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Correlation-Based Network Analysis of the Influence of

    Schutze, Inana X / Yamamoto, Pedro T / Malaquias, José B / Herritt, Matthew / Thompson, Alison / Merten, Paul / Naranjo, Steve E

    Insects

    2022  Volume 13, Issue 1

    Abstract: ... Bemisia ... ...

    Abstract Bemisia tabaci
    Language English
    Publishing date 2022-01-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662247-6
    ISSN 2075-4450
    ISSN 2075-4450
    DOI 10.3390/insects13010056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: New Australian melanoma management guidelines: the patient perspective.

    Button-Sloan, Alison E / Thompson, John F

    The Medical journal of Australia

    2020  Volume 213, Issue 9, Page(s) 400–401.e1

    MeSH term(s) Academies and Institutes ; Australia ; Health Planning Councils ; Humans ; Medical Oncology/standards ; Melanoma ; Practice Guidelines as Topic ; Skin Neoplasms
    Language English
    Publishing date 2020-10-18
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 186082-3
    ISSN 1326-5377 ; 0025-729X
    ISSN (online) 1326-5377
    ISSN 0025-729X
    DOI 10.5694/mja2.50813
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Regional specialization manifests in the reliability of neural population codes.

    Guidera, Jennifer A / Gramling, Daniel P / Comrie, Alison E / Joshi, Abhilasha / Denovellis, Eric L / Lee, Kyu Hyun / Zhou, Jenny / Thompson, Paige / Hernandez, Jose / Yorita, Allison / Haque, Razi / Kirst, Christoph / Frank, Loren M

    bioRxiv : the preprint server for biology

    2024  

    Abstract: The brain has the remarkable ability to learn and guide the performance of complex tasks. Decades of lesion studies suggest that different brain regions perform specialized functions in support of complex ... ...

    Abstract The brain has the remarkable ability to learn and guide the performance of complex tasks. Decades of lesion studies suggest that different brain regions perform specialized functions in support of complex behaviors
    Language English
    Publishing date 2024-01-26
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2024.01.25.576941
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Non-psychotic Outcomes in Young People at Ultra-High Risk of Developing a Psychotic Disorder: A Long-Term Follow-up Study.

    Spiteri-Staines, Anneliese E / Yung, Alison R / Lin, Ashleigh / Hartmann, Jessica A / Amminger, Paul / McGorry, Patrick D / Thompson, Andrew / Wood, Stephen J / Nelson, Barnaby

    Schizophrenia bulletin

    2024  

    Abstract: Background: The majority of individuals at ultra-high risk (UHR) for psychosis do not transition to a full threshold psychotic disorder. It is therefore important to understand their longer-term clinical and functional outcomes, particularly given the ... ...

    Abstract Background: The majority of individuals at ultra-high risk (UHR) for psychosis do not transition to a full threshold psychotic disorder. It is therefore important to understand their longer-term clinical and functional outcomes, particularly given the high prevalence of comorbid mental disorders in this population at baseline.
    Aims: This study investigated the prevalence of non-psychotic disorders in the UHR population at entry and long-term follow-up and their association with functional outcomes. Persistence of UHR status was also investigated.
    Study design: The sample comprised 102 UHR young people from the Personal Assessment and Crisis Evaluation (PACE) Clinic who had not transitioned to psychosis by long-term follow-up (mean = 8.8 years, range = 6.8-12.1 years since baseline).
    Results: Eighty-eight percent of participants at baseline were diagnosed with at least one mental disorder, the majority of which were mood disorders (78%), anxiety disorders (35%), and substance use disorders (SUDs) (18%). This pattern of disorder prevalence continued at follow-up, though prevalence was reduced, with 52% not meeting criteria for current non-psychotic mental disorder. However, 35% of participants developed a new non-psychotic mental disorder by follow-up. Presence of a continuous non-psychotic mental disorder was associated with poorer functional outcomes at follow-up. 28% of participants still met UHR criteria at follow-up.
    Conclusions: The study adds to the evidence base that a substantial proportion of UHR individuals who do not transition to psychosis experience persistent attenuated psychotic symptoms and persistent and incident non-psychotic disorders over the long term. Long-term treatment and re-entry into services is indicated.
    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 439173-1
    ISSN 1745-1701 ; 0586-7614
    ISSN (online) 1745-1701
    ISSN 0586-7614
    DOI 10.1093/schbul/sbae005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Worst Life Events and Media Exposure to Terrorism in a Nationally Representative U.S. Sample.

    Thompson, Rebecca R / Holman, E Alison / Silver, Roxane Cohen

    Journal of traumatic stress

    2020  Volume 33, Issue 6, Page(s) 984–993

    Abstract: Indirectly experienced negative life events are not considered Criterion A traumatic events per DSM-5 posttraumatic stress disorder diagnostic criteria, yet individuals indirectly exposed to trauma via the media may report these events as peak traumatic ... ...

    Abstract Indirectly experienced negative life events are not considered Criterion A traumatic events per DSM-5 posttraumatic stress disorder diagnostic criteria, yet individuals indirectly exposed to trauma via the media may report these events as peak traumatic experiences. We studied which events people considered to be the "worst" in their lifetimes to gain a better understanding of the types of events individuals consider to be distressing. This longitudinal study included a nationally representative sample of U.S. residents living outside New York (N = 1,606) who were exposed to the September 11th, 2001 (9/11) terror attacks exclusively via the media. Bereavement was the most frequently cited "worst" life event (42.0%); violent events were cited by 11.4% of the sample. However, 22.0% of respondents reported 9/11 as their worst life event even though they did not directly experience the attacks. More lifetime exposure to violent events and bereavement, odds ratios (ORs) = 0.79 and 0.72, respectively, and a college education, OR = 0.61, were associated with decreased odds of naming 9/11 as one's worst life event. Watching 4 or more hours of 9/11-related television coverage in the week after the attacks, OR = 1.67, and identifying as African American, OR = 2.01, were associated with increased odds of naming 9/11 as one's worst life event 1 year after the attacks. Events experienced indirectly through the media may be considered the worst of people's lives, with important implications for assessing stressful life event history and understanding indirect exposure to negative life events.
    MeSH term(s) Adult ; Female ; Humans ; Life Change Events ; Longitudinal Studies ; Male ; Mass Media ; Middle Aged ; September 11 Terrorist Attacks/psychology ; Stress Disorders, Post-Traumatic/etiology ; Stress, Psychological/etiology ; Terrorism ; United States
    Language English
    Publishing date 2020-11-20
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 639478-4
    ISSN 1573-6598 ; 0894-9867
    ISSN (online) 1573-6598
    ISSN 0894-9867
    DOI 10.1002/jts.22534
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Avoidant authority: The effect of organizational power on decision-making in high-uncertainty situations.

    Shortland, Neil D / McCusker, Maureen E / Alison, Laurence / Blacksmith, Nikki / Crayne, Matthew P / Thompson, Lisa / Gonzales, Joseph / McGarry, Presley / Stevens, Catherine

    Frontiers in psychology

    2023  Volume 13, Page(s) 1027108

    Abstract: Individuals in positions of power are often required to make high-stakes decisions. The approach-inhibition theory of social power holds that elevated power activates approach-related tendencies, leading to decisiveness and action orientation. However, ... ...

    Abstract Individuals in positions of power are often required to make high-stakes decisions. The approach-inhibition theory of social power holds that elevated power activates approach-related tendencies, leading to decisiveness and action orientation. However, naturalistic decision-making research has often reported that increased power often has the opposite effect and causes more avoidant decision-making. To investigate the potential activation of avoidance-related tendencies in response to elevated power, this study employed an immersive scenario-based battery of least-worst decisions (the Least-Worst Uncertain Choice Inventory for Emergency Responses; LUCIFER) with members of the United States Armed Forces. In line with previous naturalistic decision-making research on the effect of power, this research found that in conditions of higher power, individuals found decisions more difficult and were more likely to make an avoidant choice. Furthermore, this effect was more pronounced in domain-specific decisions for which the individual had experience. These findings expand our understanding of when, and in what contexts, power leads to approach vs. avoidant tendencies, as well as demonstrate the benefits of bridging methodological divides that exist between "in the lab" and "in the field" when studying high-uncertainty decision-making.
    Language English
    Publishing date 2023-02-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2022.1027108
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Understanding Parents' Experiences When Caring for a Child With Functional Constipation: Interpretive Description Study.

    Thompson, Alison P / MacDonald, Shannon E / Wine, Eytan / Scott, Shannon D

    JMIR pediatrics and parenting

    2021  Volume 4, Issue 1, Page(s) e24851

    Abstract: Background: Pediatric functional constipation (FC) is a common but serious medical condition. Despite significant effects on children, families, and the health care system, the condition is typically undertreated. Parents carry the primary ... ...

    Abstract Background: Pediatric functional constipation (FC) is a common but serious medical condition. Despite significant effects on children, families, and the health care system, the condition is typically undertreated. Parents carry the primary responsibility for complex treatment programs; therefore, understanding their experiences and needs may offer a critical perspective toward improving clinical care.
    Objective: The aim of this study is to understand and give voice to parents' experiences and information needs when caring for a child with FC. The ultimate objective is to build an evidence base suitable for creating a digital knowledge translation tool to better support parents caring for a child with FC.
    Methods: This qualitative design used an interpretive description methodology to generate findings aimed at improving clinical care. One-on-one, in-depth interviews were completed either in person or through web-based teleconferencing to explore parents' perspectives. Data collection and analysis occurred concurrently.
    Results: Analysis of 16 interviews generated 4 major themes: living in the shadows; not taken seriously, with a subtheme of persevering and advocating; missing information and misinformation; and self-doubt and strained relationships. One minor theme of affirmative influences that foster resilience and hope was identified.
    Conclusions: Parents have unmet needs for support and information related to pediatric FC. To address gaps in current care provision, decision makers may consider interventions for clinicians, resources for parents, and shifting care models to better meet parents' needs.
    Language English
    Publishing date 2021-01-20
    Publishing country Canada
    Document type Journal Article
    ISSN 2561-6722
    ISSN (online) 2561-6722
    DOI 10.2196/24851
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Rapid and precise genotyping of transgene zygosity in mice using an allele-specific method.

    Yang, Jianqi / DeVore, Alison N / Fu, Daniel A / Spicer, Mackenzie M / Guo, Mengcheng / Thompson, Samantha G / Ahlers-Dannen, Katelin E / Polato, Federica / Nussenzweig, Andre / Fisher, Rory A

    Life science alliance

    2023  Volume 6, Issue 6

    Abstract: Precise determination of transgene zygosity is essential for use of transgenic mice in research. Because integration loci of transgenes are usually unknown due to their random insertion, assessment of transgene zygosity remains a challenge. Current ... ...

    Abstract Precise determination of transgene zygosity is essential for use of transgenic mice in research. Because integration loci of transgenes are usually unknown due to their random insertion, assessment of transgene zygosity remains a challenge. Current zygosity genotyping methods (progeny testing, qPCR, and NGS-computational biology analysis) are time consuming, prone to error or technically challenging. Here, we developed a novel method to determine transgene zygosity requiring no knowledge of transgene insertion loci. This method applies allele-specific restriction enzyme digestion of PCR products (RE/PCR) to rapidly and reliably quantify transgene zygosity. We demonstrate the applicability of this method to three transgenic strains of mice (
    MeSH term(s) Mice ; Animals ; Genotype ; Alleles ; Transgenes/genetics ; Mice, Transgenic ; Base Sequence
    Language English
    Publishing date 2023-04-10
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ISSN 2575-1077
    ISSN (online) 2575-1077
    DOI 10.26508/lsa.202201729
    Database MEDical Literature Analysis and Retrieval System OnLINE

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