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  1. Article: New Data on the Epidemiology of Breast Implant-Associated Anaplastic Large Cell Lymphoma.

    Ionescu, Paul / Vibert, Florence / Amé, Shanti / Mathelin, Carole

    European journal of breast health

    2021  Volume 17, Issue 4, Page(s) 302–307

    Abstract: Objective: This study aimed to illustrate the epidemiological situation of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) by focusing on the changes published after 2019 and particularly the new approaches of cosmetic and ... ...

    Abstract Objective: This study aimed to illustrate the epidemiological situation of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) by focusing on the changes published after 2019 and particularly the new approaches of cosmetic and reconstructive breast surgery.
    Materials and methods: Article search was performed from January 2019 to date using the PubMed database. Fourteen articles were included in the qualitative evaluation of international data. Moreover, the latest reports regarding the total number of BIA-ALCL cases and number of deaths were identified.
    Results: Estimates of the risk and incidence have increased significantly recently, affecting 1 in every 2,969 women with breast implants and 1 in 355 patients with textured implants after breast reconstruction. The average exposure time to diagnosis was 8 (range: 0-34) years. Approximately 80% of BIA-ALCL cases were diagnosed at IA-IIA stages, for which the treatment was breast implant removal, full capsulectomy, and excision of all suspected lymph nodes. Globally, at least 949 cases were reported to date.
    Conclusion: At present, BIA-ALCL is an emerging pathology of interest. Data collection initiated since 2016 through different case registration databases is essential to ensure surveillance and to continue to increase the number of studies on this recently discovered pathology.
    Language English
    Publishing date 2021-10-04
    Publishing country Turkey
    Document type Journal Article ; Review
    ISSN 2587-0831
    ISSN 2587-0831
    DOI 10.4274/ejbh.galenos.2021.2021-5-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Accuracy of prenatal detection of facial clefts and relation between facial clefts, additional malformations and chromosomal abnormalities: a large referral-center cohort.

    Vibert, Florence / Schmidt, Guel / Löffler, Kerstin / Gasiorek-Wiens, Adam / Henrich, Wolfgang / Verlohren, Stefan

    Archives of gynecology and obstetrics

    2023  Volume 309, Issue 5, Page(s) 1971–1980

    Abstract: Purpose: Facial clefts belong to the most common congenital malformations and their prenatal diagnosis is a constant challenge. The aim of this study was to determine the accuracy of prenatal ultrasound in correctly classifying facial clefts. ... ...

    Abstract Purpose: Facial clefts belong to the most common congenital malformations and their prenatal diagnosis is a constant challenge. The aim of this study was to determine the accuracy of prenatal ultrasound in correctly classifying facial clefts. Furthermore, we aimed to specify the distribution of the type of clefts and underlying genetic conditions.
    Methods: All fetuses seen with suspected facial cleft in the Department of Obstetrics, Charité - Universitätsmedizin Berlin during a period of 23 years (1999-2022) were included in this retrospective study. Clefts were classified according to the classification of Nyberg. All additional prenatal findings were assessed and correlated with the outcome. The accuracy of prenatal diagnosis was assessed.
    Results: 292 patients were included in the study. The most common type of clefts were unilateral cleft lip and palate (CL-P) (53.6%) and bilateral CL-P (30.6%), followed by CL (8.1%), CP (5.1%) and median CL-P (2.6%). The overall pre- and postnatal concordance rate corresponding to a correct prenatal diagnosis was high, 88.9%, ranging from 73.7% (CL) to 93.7% (unilateral CL-P). Most of the median clefts (95.2%) and CP (93.3%) were associated with other sonographic abnormalities, as well as 52.2% of bilateral CL-P. Chromosomal abnormalities, mostly trisomy 13 and trisomy 18, were observed in in the median CL-P (47.6%), bilateral CL-P (31.1%) and CP (26.7%) groups, in contrast to the CL (9.1%) and unilateral CL-P (12.9%) groups. It was exceptional to have a chromosomal abnormality without additional malformations (4.8%). The mortality rate including one late miscarriage, 5 IUFD's, 74 TOPs and 6 palliative cares at birth was 29.8%, particularly high for median clefts (90.5%).
    Conclusion: Prenatal ultrasound exhibited a high accuracy to assess the type of facial clefts with an average rate of 88.9% (73.7%-93.7%) and a concordance rate of up to 93.7%, depending on the type of cleft. The search for additional malformations as well as clarifying underlying genetic conditions is essential. This allows for a targeted counseling of the parents and to best prepare for postnatal care, including surgery by the maxillofacial team.
    MeSH term(s) Female ; Infant, Newborn ; Humans ; Pregnancy ; Cleft Lip/diagnostic imaging ; Cleft Lip/genetics ; Cleft Lip/complications ; Cleft Palate/diagnostic imaging ; Cleft Palate/genetics ; Retrospective Studies ; Chromosome Aberrations ; Prenatal Diagnosis ; Ultrasonography, Prenatal
    Language English
    Publishing date 2023-06-16
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 896455-5
    ISSN 1432-0711 ; 0932-0067
    ISSN (online) 1432-0711
    ISSN 0932-0067
    DOI 10.1007/s00404-023-07084-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: New Data on the Epidemiology of Breast Implant-Associated Anaplastic Large Cell Lymphoma

    Paul Ionescu / Florence Vibert / Shanti Amé / Carole Mathelin

    European Journal of Breast Health, Vol 17, Iss 4, Pp 302-

    2021  Volume 307

    Abstract: Objective:This study aimed to illustrate the epidemiological situation of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) by focusing on the changes published after 2019 and particularly the new approaches of cosmetic and ... ...

    Abstract Objective:This study aimed to illustrate the epidemiological situation of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) by focusing on the changes published after 2019 and particularly the new approaches of cosmetic and reconstructive breast surgery.Materials and Methods:Article search was performed from January 2019 to date using the PubMed database. Fourteen articles were included in the qualitative evaluation of international data. Moreover, the latest reports regarding the total number of BIA-ALCL cases and number of deaths were identified.Results:Estimates of the risk and incidence have increased significantly recently, affecting 1 in every 2,969 women with breast implants and 1 in 355 patients with textured implants after breast reconstruction. The average exposure time to diagnosis was 8 (range: 0–34) years. Approximately 80% of BIA-ALCL cases were diagnosed at IA–IIA stages, for which the treatment was breast implant removal, full capsulectomy, and excision of all suspected lymph nodes. Globally, at least 949 cases were reported to date.Conclusion:At present, BIA-ALCL is an emerging pathology of interest. Data collection initiated since 2016 through different case registration databases is essential to ensure surveillance and to continue to increase the number of studies on this recently discovered pathology.
    Keywords breast cancer ; breast cancer surgery ; anaplastic large cell lymphoma ; Neoplasms. Tumors. Oncology. Including cancer and carcinogens ; RC254-282 ; Medicine ; R
    Subject code 616
    Language English
    Publishing date 2021-10-01T00:00:00Z
    Publisher Galenos Publishing House
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: A New Modality for Breast Cancer Diagnosis During the COVID-19 Pandemic

    Florence Vibert / Camille Martel / Raluca Andreea Ionescu / Carole Mathelin / Shanti Ame

    European Journal of Breast Health, Vol 18, Iss 1, Pp 91-

    A Case Report

    2022  Volume 93

    Abstract: Organized screening for breast cancer (BC) was suspended in most countries of the world during the coronavirus disease-2019 (COVID-19) pandemic. Com-puted tomography (CT) scans of the chest, frequently performed in patients with severe forms of COVID-19, ...

    Abstract Organized screening for breast cancer (BC) was suspended in most countries of the world during the coronavirus disease-2019 (COVID-19) pandemic. Com-puted tomography (CT) scans of the chest, frequently performed in patients with severe forms of COVID-19, may detect asymptomatic breast abnormalities. A 72-year-old patient, with a severe form of COVID-19 underwent a diagnostic CT scan. This led to the unexpected discovery, at an early stage, of a 12 mm, high grade, Human epidermal growth factor receptor 2 positive BC, with a high proliferation index. After responding to chemotherapy, she was managed with conser-vative breast surgery with sentinel lymph node biopsy. Delayed management of BC can be responsible for poor outcomes. Patients with severe forms of COVID-19 are also at risk for developing BC due to common risk factors. Thirty percent of incidental breast lesions discovered on CT scans are undiagnosed BC. Careful study of the mammary glands on CT scan of patients with COVID-19 may allow early diagnosis of a malignant tumor in a high-risk population for BC and deprived of routine screening mammography.
    Keywords breast cancer ; covid-19 ; sars-cov-2 ; screening ; chest scan ; Neoplasms. Tumors. Oncology. Including cancer and carcinogens ; RC254-282 ; Medicine ; R
    Subject code 610 ; 616
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Galenos Publishing House
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: A New Modality for Breast Cancer Diagnosis During the COVID-19 Pandemic: A Case Report.

    Vibert, Florence / Martel, Camille / Ionescu, Raluca Andreea / Mathelin, Carole / Ame, Shanti

    European journal of breast health

    2021  Volume 18, Issue 1, Page(s) 91–93

    Abstract: Organized screening for breast cancer (BC) was suspended in most countries of the world during the coronavirus disease-2019 (COVID-19) pandemic. Com-puted tomography (CT) scans of the chest, frequently performed in patients with severe forms of COVID-19, ...

    Abstract Organized screening for breast cancer (BC) was suspended in most countries of the world during the coronavirus disease-2019 (COVID-19) pandemic. Com-puted tomography (CT) scans of the chest, frequently performed in patients with severe forms of COVID-19, may detect asymptomatic breast abnormalities. A 72-year-old patient, with a severe form of COVID-19 underwent a diagnostic CT scan. This led to the unexpected discovery, at an early stage, of a 12 mm, high grade, Human epidermal growth factor receptor 2 positive BC, with a high proliferation index. After responding to chemotherapy, she was managed with conser-vative breast surgery with sentinel lymph node biopsy. Delayed management of BC can be responsible for poor outcomes. Patients with severe forms of COVID-19 are also at risk for developing BC due to common risk factors. Thirty percent of incidental breast lesions discovered on CT scans are undiagnosed BC. Careful study of the mammary glands on CT scan of patients with COVID-19 may allow early diagnosis of a malignant tumor in a high-risk population for BC and deprived of routine screening mammography.
    Language English
    Publishing date 2021-12-30
    Publishing country Turkey
    Document type Case Reports
    ISSN 2587-0831
    ISSN 2587-0831
    DOI 10.4274/ejbh.galenos.2021.2021-4-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Prone positioning and high-flow oxygen improved respiratory function in a 25-week pregnant woman with COVID-19.

    Vibert, Florence / Kretz, Mathilda / Thuet, Vincent / Barthel, Florian / De Marcillac, Fanny / Deruelle, Philippe / Lecointre, Lise

    European journal of obstetrics, gynecology, and reproductive biology

    2020  Volume 250, Page(s) 257–258

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/physiopathology ; Coronavirus Infections/therapy ; Coronavirus Infections/virology ; Female ; Humans ; Lung/physiopathology ; Oxygen Inhalation Therapy/methods ; Pandemics ; Patient Positioning/methods ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/therapy ; Pneumonia, Viral/virology ; Pregnancy ; Pregnancy Complications, Infectious/physiopathology ; Pregnancy Complications, Infectious/therapy ; Pregnancy Complications, Infectious/virology ; Prone Position ; SARS-CoV-2 ; Young Adult
    Keywords covid19
    Language English
    Publishing date 2020-05-13
    Publishing country Ireland
    Document type Case Reports ; Letter
    ZDB-ID 190605-7
    ISSN 1872-7654 ; 0301-2115 ; 0028-2243
    ISSN (online) 1872-7654
    ISSN 0301-2115 ; 0028-2243
    DOI 10.1016/j.ejogrb.2020.05.022
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    Zs.A 837: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  7. Article ; Online: Effect of acute nitrate and citrulline supplementation on muscle microvascular response to ischemia-reperfusion in healthy humans.

    Le Roux-Mallouf, Thibault / Vibert, Florence / Doutreleau, Stéphane / Verges, Samuel

    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme

    2017  Volume 42, Issue 9, Page(s) 901–908

    Abstract: Nitric oxide (NO) is implicated in vasomotor control mechanisms altering the diameter of the vessels under various physiological and pathological conditions. There are 2 main NO production pathways, 1 NO synthase (NOS) independent (nitrate-nitrite-NO) ... ...

    Abstract Nitric oxide (NO) is implicated in vasomotor control mechanisms altering the diameter of the vessels under various physiological and pathological conditions. There are 2 main NO production pathways, 1 NO synthase (NOS) independent (nitrate-nitrite-NO) and the other is NOS dependent (citrulline-arginine-NO). The objective of the study was to evaluate the effect of acute nitrate and citrulline supplementation on post-ischemic vascular response in healthy subjects. Fourteen subjects performed 2-leg vascular occlusion tests, 3 days apart. They were randomly assigned to consume a drink containing 1200 mg (19.4 mmol) of nitrate and 6 g of citrulline (N+C) or a placebo (Pl). Changes in total hemoglobin (Hbtot) and oxyhemoglobin (HbO
    Language English
    Publishing date 2017-09
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2236708-1
    ISSN 1715-5320 ; 1715-5312
    ISSN (online) 1715-5320
    ISSN 1715-5312
    DOI 10.1139/apnm-2017-0081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Lynch syndrome: influence of additional susceptibility variants on cancer risk.

    Vibert, Roseline / Hasnaoui, Jasmine / Perrier, Alexandre / Lefebvre, Alexandra / Colas, Chrystelle / Dhooge, Marion / Basset, Noémie / Chansavang, Albain / Desseignes, Camille / Duval, Alex / Farelly, Solenne / Hamzaoui, Nadim / Laurent-Puig, Pierre / Metras, Julie / Moliere, Diane / Muleris, Martine / Netter, Jeanne / Touat, Mehdi / Bielle, Franck /
    Labreche, Karim / Nicolle, Romain / Perkins, Géraldine / Warcoin, Mathilde / Coulet, Florence / Benusiglio, Patrick R

    European journal of human genetics : EJHG

    2023  Volume 31, Issue 9, Page(s) 1078–1082

    Abstract: Some patients with Lynch syndrome (LS) have extreme phenotypes, i.e. cancer before the recommended screening age, or cancer for which there are no screening guidelines. We made the hypothesis that additional germline variants in cancer susceptibility ... ...

    Abstract Some patients with Lynch syndrome (LS) have extreme phenotypes, i.e. cancer before the recommended screening age, or cancer for which there are no screening guidelines. We made the hypothesis that additional germline variants in cancer susceptibility genes (CSG) could explain some of these phenotypes. We compared the prevalence of additional CSG variants in LS patients with a cancer diagnosis before age 30 (early-onset, EO group) and after 40 (usual-onset, UO group). While there was no overall difference, we did find an excess of pathogenic variants and variants of unknown significance in EO cases when only gastrointestinal CSG were considered (OR 2.25; 95% CI: 1.01-5.06, p value = 0.04). Four EO cases stood out: two with POLE/POLD1 variants in the key exonuclease domain, one with a BMPR1A duplication and one with an EPCAM deletion. Additional germline variants should be considered in future screening recommendations, as they might influence cancer risk.
    MeSH term(s) Humans ; Colorectal Neoplasms, Hereditary Nonpolyposis/diagnosis ; Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; Colorectal Neoplasms, Hereditary Nonpolyposis/pathology ; Germ-Line Mutation ; Risk ; Phenotype
    Language English
    Publishing date 2023-04-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 1141470-4
    ISSN 1476-5438 ; 1018-4813
    ISSN (online) 1476-5438
    ISSN 1018-4813
    DOI 10.1038/s41431-023-01367-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3589: Show issues Location:
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  9. Article: Prone positioning and high-flow oxygen improved respiratory function in a 25-week pregnant woman with COVID-19

    Vibert, Florence / Kretz, Mathilda / Thuet, Vincent / Barthel, Florian / De Marcillac, Fanny / Deruelle, Philippe / Lecointre, Lise

    Eur J Obstet Gynecol Reprod Biol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #245750
    Database COVID19

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  10. Article ; Online: Prone positioning and high-flow oxygen improved respiratory function in a 25-week pregnant woman with COVID-19

    Vibert, Florence / Kretz, Mathilda / Thuet, Vincent / Barthel, Florian / De Marcillac, Fanny / Deruelle, Philippe / Lecointre, Lise

    European Journal of Obstetrics & Gynecology and Reproductive Biology

    2020  Volume 250, Page(s) 257–258

    Keywords Obstetrics and Gynaecology ; Reproductive Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 190605-7
    ISSN 1872-7654 ; 0301-2115 ; 0028-2243
    ISSN (online) 1872-7654
    ISSN 0301-2115 ; 0028-2243
    DOI 10.1016/j.ejogrb.2020.05.022
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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