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Article ; Online: Necrotic lesions of the hands

Davide Bastoni / Erika Poggiali

Emergency Care Journal, Vol 18, Iss

2022 Volume 1

Abstract: An 82-year-old man with a history of end-stage renal disease due to glomerulonephritis requiring haemodialysis, hepatitis C-related liver cirrhosis and hypertensive cardiomyopathy presented with painful and necrotic lesions of both his hands. He had no ... ...

Abstract	An 82-year-old man with a history of end-stage renal disease due to glomerulonephritis requiring haemodialysis, hepatitis C-related liver cirrhosis and hypertensive cardiomyopathy presented with painful and necrotic lesions of both his hands. He had no other symptoms. [.]
Keywords	Cryoglobulinemia ; vasculitis ; necrotic skin lesions ; hepatitis C virus ; CryoVas ; Medicine (General) ; R5-920
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	PAGEPress Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A call to action against gender-based violence and discrimination from the Emergency Departments

Erika Poggiali / Davide Bastoni / Carlo Fraticelli / Massimiliano Beghi / Daniele Coen / Lorenzo Ghiadoni

Emergency Care Journal, Vol 19, Iss

2023 Volume 4

Abstract: Gender-based violence (GBV) is a global issue deeply rooted that grows from gender inequality and represents one of the most severe human rights violations. GBV is violence directed against a person because of their gender. It may include both ... ...

Abstract	Gender-based violence (GBV) is a global issue deeply rooted that grows from gender inequality and represents one of the most severe human rights violations. GBV is violence directed against a person because of their gender. It may include both intimidation and manipulation in addition to sexual, physical, mental, and financial harm done in secret or in a public context. The consequences of GBV can be devastating, with life-long consequences for survivors, or even result in death. Although GBV affects both men and women, the burden belongs mainly to women and girls. According to the 2015 Italian National Institute of Statistics report, almost 1 out of 3 women in Italy have disclosed physical and/or sexual violence. Thirty-one percent of women aged 16—70 have experienced some form of violence (20% physical and 21% sexual violence).1 Up to December 3, 2023, 109 women had died in Italy, 90 of whom in domestic settings, and 58 had been killed by partners or former partners. Analysing the data from the first nine months of 2023 of calls to the national ‘Anti-violence and anti-stalking’ helpline (1522), approximately half of the victims (47.6%) were victims of physical violence. Psychological violence was the second most frequent reason for calling (36.9%). Most of them (79.4%) are victims of domestic violence. Only 15.8% reported the type of violence they suffered (1,311 victims),2 even if the Italian law ensures greater protection for victims and legal aid. [.]
Keywords	Gender based violence ; domestic violence ; discrimination ; anti-discrimination admission pathway ; Medicine (General) ; R5-920
Subject code	390
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	PAGEPress Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Deep Vein Thrombosis and Pulmonary Embolism: Two Complications of COVID-19 Pneumonia?

Poggiali, Erika / Bastoni, Davide / Ioannilli, Eva / Vercelli, Andrea / Magnacavallo, Andrea

European journal of case reports in internal medicine

2020 Volume 7, Issue 5, Page(s) 1646

Abstract: Coronavirus disease 19 (COVID-19) is a worldwide infection which was recently declared a global health emergency by the WHO Emergency Committee. The most common symptoms are fever and cough, which can progress to pneumonia, acute respiratory distress ... ...

Abstract	Coronavirus disease 19 (COVID-19) is a worldwide infection which was recently declared a global health emergency by the WHO Emergency Committee. The most common symptoms are fever and cough, which can progress to pneumonia, acute respiratory distress syndrome (ARDS) and/or end-organ failure. Risk factors associated with ARDS and death are older age, comorbidities (e.g., hypertension, diabetes, hyperlipidaemia), neutrophilia, and organ and coagulation dysfunction. Disseminated intravascular coagulation and coagulopathy can contribute to death. Anticoagulant treatment is associated with decreased mortality in severe COVID-19 pneumonia. In this report we describe two patients with COVID-19 pneumonia who developed venous thromboembolism. Learning points: Deep vein thrombosis and pulmonary embolism can occur in patients with COVID-19 pneumonia.Low-molecular-weight heparin prophylaxis does not decrease the risk of venous thromboembolism (VTE) in COVID-19 pneumonia.In the presence of clinical signs and/or suspicion of VTE, compression ultrasound and echocardiography should be always performed, irrespective of disease stage.
Keywords	covid19
Language	English
Publishing date	2020-04-08
Publishing country	Italy
Document type	Journal Article
ISSN	2284-2594
ISSN (online)	2284-2594
DOI	10.12890/2020_001646
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: COVID-19 and cutaneous manifestations

Davide Bastoni / Giorgia Borio / Paola Rienzo / Andrea Magnacavallo / Andrea Vercelli / Erika Poggiali

Emergency Care Journal, Vol 18, Iss

Two cases and a review of the literature

2022 Volume 2

Abstract: COVID-19 can affect multiple organs, including skin. A wide range of skin manifestations have been reported in literature. Six main phenotypes have been identified: i) urticarial rash, ii) confluent erythematous/maculopapular/morbilliform rash, iii) ... ...

Abstract	COVID-19 can affect multiple organs, including skin. A wide range of skin manifestations have been reported in literature. Six main phenotypes have been identified: i) urticarial rash, ii) confluent erythematous/maculopapular/morbilliform rash, iii) papulovesicular exanthem, iv) a chilblain-like acral pattern, v) a livedo reticularis/racemosa-like pattern, and vi) a purpuric vasculitic pattern. The pathogenetic mechanism is still not completely clear, but a role of hyperactive immune response, complement activation and microvascular injury have been postulated. The only correlation between the cutaneous phenotype and the severity of COVID-19 has been observed in the case of chilblain-like acral lesions, that is generally associated with the benign/subclinical course of COVID-19. Herein, we report two cases of SARS-CoV- 2 infection in patients who developed cutaneous manifestations that completely solved with systemic steroids and antihistamines. The first case is a female patient not vaccinated for SARS-CoV-2 with COVID-19 associated pneumonia, while the second case is a vaccinated female patient with only skin manifestations.
Keywords	COVID-19 ; SARS-CoV-2 ; skin manifestations ; coronavirus ; angioedema ; urticaria ; Medicine (General) ; R5-920
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	PAGEPress Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Deep Vein Thrombosis and Pulmonary Embolism

Erika Poggiali / Davide Bastoni / Eva Ioannilli / Andrea Vercelli / Andrea Magnacavallo

European Journal of Case Reports in Internal Medicine (2020)

Two Complications of COVID-19 Pneumonia?

2020

Abstract	Coronavirus disease 19 (COVID-19) is a worldwide infection which was recently declared a global health emergency by the WHO Emergency Committee. The most common symptoms are fever and cough, which can progress to pneumonia, acute respiratory distress syndrome (ARDS) and/or end-organ failure. Risk factors associated with ARDS and death are older age, comorbidities (e.g., hypertension, diabetes, hyperlipidaemia), neutrophilia, and organ and coagulation dysfunction. Disseminated intravascular coagulation and coagulopathy can contribute to death. Anticoagulant treatment is associated with decreased mortality in severe COVID-19 pneumonia. In this report we describe two patients with COVID-19 pneumonia who developed venous thromboembolism.
Keywords	covid-19 pneumonia ; deep vein thrombosis ; venous thromboembolism ; pulmonary embolism ; heparin ; Medicine ; R ; covid19
Language	English
Publishing date	2020-04-01T00:00:00Z
Publisher	SMC MEDIA SRL
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Prone positioning in patients treated with non-invasive ventilation for COVID-19 pneumonia in an Italian emergency department.

Bastoni, Davide / Poggiali, Erika / Vercelli, Andrea / Demichele, Elena / Tinelli, Valentina / Iannicelli, Teresa / Magnacavallo, Andrea

Emergency medicine journal : EMJ

2020 Volume 37, Issue 9, Page(s) 565–566

Abstract: We report the experience of prone ventilation in selected patients treated with helmet non-invasive ventilation (NIV) continuous positive airway pressure (CPAP) for acute respiratory failure in COVID-19 pneumonia. Preliminary results showed an ... ...

Abstract	We report the experience of prone ventilation in selected patients treated with helmet non-invasive ventilation (NIV) continuous positive airway pressure (CPAP) for acute respiratory failure in COVID-19 pneumonia. Preliminary results showed an improvement in the PaO
MeSH term(s)	Aged ; Betacoronavirus/isolation & purification ; COVID-19 ; Continuous Positive Airway Pressure/methods ; Coronavirus Infections/complications ; Coronavirus Infections/epidemiology ; Coronavirus Infections/physiopathology ; Coronavirus Infections/therapy ; Emergency Service, Hospital/statistics & numerical data ; Female ; Humans ; Italy/epidemiology ; Male ; Noninvasive Ventilation/methods ; Oxygen Consumption ; Oxygen Inhalation Therapy/methods ; Pandemics ; Patient Positioning ; Pneumonia, Viral/complications ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/etiology ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/therapy ; Prone Position ; Respiratory Insufficiency/etiology ; Respiratory Insufficiency/physiopathology ; Respiratory Insufficiency/therapy ; SARS-CoV-2 ; Treatment Outcome
Keywords	covid19
Language	English
Publishing date	2020-07-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2040124-3
ISSN	1472-0213 ; 1472-0205
ISSN (online)	1472-0213
ISSN	1472-0205
DOI	10.1136/emermed-2020-209744
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Article ; Online: From the Triage to the Intermediate Area: A Simple and Fast Model for COVID-19 in the Emergency Department.

Poggiali, Erika / Fabrizi, Enrico / Bastoni, Davide / Iannicelli, Teresa / Galluzzo, Claudia / Canini, Chiara / Cillis, Maria Grazia / Ponzi, Davide Giulio / Magnacavallo, Andrea / Vercelli, Andrea

International journal of environmental research and public health

2022 Volume 19, Issue 13

Abstract: Introduction: The early identification of patients with SARS-CoV-2 infection is still a real challenge for emergency departments (ED). First, we aimed to develop a score, based on the use of the lung ultrasonography (LUS), in addition to the pre-triage ... ...

Abstract	Introduction: The early identification of patients with SARS-CoV-2 infection is still a real challenge for emergency departments (ED). First, we aimed to develop a score, based on the use of the lung ultrasonography (LUS), in addition to the pre-triage interview, to correctly address patients; second, we aimed to prove the usefulness of a three-path organization (COVID-19, not-COVID-19 and intermediate) compared to a two-path organization (COVID-19, non-COVID-19). Methods: We retrospectively analysed 292 patients admitted to our ED from 10 April to 15 April 2020, with a definite diagnosis of positivity (93 COVID-19 patients) or negativity (179 not-COVID-19 patients) for SARS-COV-2 infection. Using a logistic regression, we found a set of predictors for infection selected from the pre-triage interview items and the LUS findings, which contribute with a different weight to the final score. Then, we compared the organization of two different pathways. Results: The most informative factors for classifying the patient are known nasopharyngeal swab positivity, close contact with a COVID-19 patient, fever associated with respiratory symptoms, respiratory failure, anosmia or dysgeusia, and the ultrasound criteria of diffuse alveolar interstitial syndrome, absence of B-lines and presence of pleural effusion. Their sensitivity, specificity, accuracy, and AUC-ROC are, respectively, 0.83, 0.81, 0.82 and 0.81. The most significant difference between the two pathways is the percentage of not-COVID-19 patients assigned to the COVID-19 area, that is, 10.6% (19/179) in the three-path organization, and 18.9% (34/179) in the two-path organization ( Conclusions: Our study suggests the possibility to use a score based on the pre-triage interview and the LUS findings to correctly manage the patients admitted to the ED, and the importance of an intermediate area to limit the spread of SARS-CoV-2 in the ED and, as a consequence, in the hospital.
MeSH term(s)	COVID-19/diagnosis ; Emergency Service, Hospital ; Humans ; Lung/diagnostic imaging ; Retrospective Studies ; SARS-CoV-2 ; Triage ; Ultrasonography
Language	English
Publishing date	2022-06-30
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph19138070
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Article ; Online: Abdominal Pain: A Real Challenge in Novel COVID-19 Infection.

Poggiali, Erika / Mateo Ramos, Pau / Bastoni, Davide / Vercelli, Andrea / Magnacavallo, Andrea

European journal of case reports in internal medicine

2020 Volume 7, Issue 4, Page(s) 1632

Abstract: COVID-19 (coronavirus disease 19) is an infectious disease caused by coronavirus 2019-nCoV. Since its detection in China at the end of 2019, the novel coronavirus has rapidly spread throughout the world and has caused an international public health ... ...

Abstract	COVID-19 (coronavirus disease 19) is an infectious disease caused by coronavirus 2019-nCoV. Since its detection in China at the end of 2019, the novel coronavirus has rapidly spread throughout the world and has caused an international public health emergency. The most common manifestation is flu-like symptoms. Mild infections usually improve within a few days, but COVID-19 can cause severe pneumonia with acute respiratory distress syndrome and death. Gastrointestinal symptoms are less common but possible and more difficult to recognize as part of a COVID-19 syndrome. In line with the current opinion of the WHO, we strongly believe that preventive measures and early diagnosis of COVID-19 are crucial to interrupt virus spread and avoid local outbreaks. We report the cases of COVID-19 patients admitted to our Emergency Department who complained of gastrointestinal symptoms at admission. Learning points: The novel COVID-19 infection is a severe public health problem which is causing an increasing number of deaths worldwide.Although uncommon, there may be a relationship between gastrointestinal symptoms and COVID-19, as reported in recent studies.Early detection and isolation of patients with COVID-19 infection is the only way to control and limit the global spread of this virus.
Keywords	covid19
Language	English
Publishing date	2020-03-26
Publishing country	Italy
Document type	Journal Article
ISSN	2284-2594
ISSN (online)	2284-2594
DOI	10.12890/2020_001632
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Deep vein thrombosis and pulmonary embolism: Two complications of COVID-19 pneumonia?

Poggiali, Erika / Bastoni, Davide / Ioannilli, Eva / Vercelli, Andrea / Magnacavallo, Andrea

Eur. J. Case Rep. Intern. Med.

Abstract	Coronavirus disease 19 (COVID-19) is a worldwide infection which was recently declared a global health emergency by the WHO Emergency Committee. The most common symptoms are fever and cough, which can progress to pneumonia, acute respiratory distress syndrome (ARDS) and/or end-organ failure. Risk factors associated with ARDS and death are older age, comorbidities (e.g., hypertension, diabetes, hyperlipidaemia), neutrophilia, and organ and coagulation dysfunction. Disseminated intravascular coagulation and coagulopathy can contribute to death. Anticoagulant treatment is associated with decreased mortality in severe COVID-19 pneumonia. In this report we describe two patients with COVID-19 pneumonia who developed venous thromboembolism.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #255605
Database	COVID19

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Article ; Online: From the Triage to the Intermediate Area

Erika Poggiali / Enrico Fabrizi / Davide Bastoni / Teresa Iannicelli / Claudia Galluzzo / Chiara Canini / Maria Grazia Cillis / Davide Giulio Ponzi / Andrea Magnacavallo / Andrea Vercelli

International Journal of Environmental Research and Public Health, Vol 19, Iss 8070, p

A Simple and Fast Model for COVID-19 in the Emergency Department

2022 Volume 8070

Abstract	Introduction: The early identification of patients with SARS-CoV-2 infection is still a real challenge for emergency departments (ED). First, we aimed to develop a score, based on the use of the lung ultrasonography (LUS), in addition to the pre-triage interview, to correctly address patients; second, we aimed to prove the usefulness of a three-path organization (COVID-19, not-COVID-19 and intermediate) compared to a two-path organization (COVID-19, non-COVID-19). Methods: We retrospectively analysed 292 patients admitted to our ED from 10 April to 15 April 2020, with a definite diagnosis of positivity (93 COVID-19 patients) or negativity (179 not-COVID-19 patients) for SARS-COV-2 infection. Using a logistic regression, we found a set of predictors for infection selected from the pre-triage interview items and the LUS findings, which contribute with a different weight to the final score. Then, we compared the organization of two different pathways. Results: The most informative factors for classifying the patient are known nasopharyngeal swab positivity, close contact with a COVID-19 patient, fever associated with respiratory symptoms, respiratory failure, anosmia or dysgeusia, and the ultrasound criteria of diffuse alveolar interstitial syndrome, absence of B-lines and presence of pleural effusion. Their sensitivity, specificity, accuracy, and AUC-ROC are, respectively, 0.83, 0.81, 0.82 and 0.81. The most significant difference between the two pathways is the percentage of not-COVID-19 patients assigned to the COVID-19 area, that is, 10.6% (19/179) in the three-path organization, and 18.9% (34/179) in the two-path organization ( p = 0.037). Conclusions: Our study suggests the possibility to use a score based on the pre-triage interview and the LUS findings to correctly manage the patients admitted to the ED, and the importance of an intermediate area to limit the spread of SARS-CoV-2 in the ED and, as a consequence, in the hospital.
Keywords	COVID-19 ; SARS-CoV-2 ; lung ultrasound ; emergency department ; triage ; score ; Medicine ; R
Subject code	616
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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