Article ; Online: Severe Acute Respiratory Syndrome-Coronavirus-2 Antibody Status at the Time of Delivery and the Risk of Preeclampsia.
American journal of perinatology
2023
Abstract: Objective: Our objective was to evaluate the association between severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) serologic status in immunologically naive patients and the risk of preeclampsia at the time of delivery.: Study design: We ...
Abstract | Objective: Our objective was to evaluate the association between severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) serologic status in immunologically naive patients and the risk of preeclampsia at the time of delivery. Study design: We conducted a retrospective cohort study of pregnant patients admitted to our institution from August 1 to September 30, 2020. We recorded maternal medical and obstetric characteristics and SARS-CoV-2 serologic status. Our primary outcome was the incidence of preeclampsia. Antibody testing was performed, and patients were classified into seropositive groups: immunoglobulin (Ig)G + , IgM + , or both IgG+ and IgM + . Bivariate and multivariable analyses were performed. Results: We included 275 patients that were negative for SARS-CoV-2 antibodies, and 165 that were positive. Seropositivity was not associated with higher rates of preeclampsia ( Conclusion: We found that in an obstetric population, there was no association between SARS-CoV-2 antibody status and the risk of preeclampsia. Key points: · Pregnant people with acute COVID-19 are at an increased risk of developing preeclampsia.. · Seroconversion during pregnancy was not associated with an increased risk of preeclampsia.. · Further study regarding the timing of infection and its association with preeclampsia is necessary.. |
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Language | English |
Publishing date | 2023-06-26 |
Publishing country | United States |
Document type | Journal Article |
ZDB-ID | 605671-4 |
ISSN | 1098-8785 ; 0735-1631 |
ISSN (online) | 1098-8785 |
ISSN | 0735-1631 |
DOI | 10.1055/a-2099-8758 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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