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  1. Article: Effect of Multidirectional Forging and Aging Treatment on Wear Properties of ZK61 Alloy.

    Zhang, Xuhui / Xu, Jian / He, Wenyu / Jia, Jingjing

    Materials (Basel, Switzerland)

    2024  Volume 17, Issue 2

    Abstract: This study investigated the effects of multidirectional forging (MDF) and aging treatments on the wear properties of ZK61 magnesium alloy. Dry sliding wear tests were performed on homogenized, MDF, and aged samples using a friction wear machine to ... ...

    Abstract This study investigated the effects of multidirectional forging (MDF) and aging treatments on the wear properties of ZK61 magnesium alloy. Dry sliding wear tests were performed on homogenized, MDF, and aged samples using a friction wear machine to analyze the surface morphology by scanning electron microscopy (SEM) and white light interferometry, as well as the hardness and tensile mechanical properties. The ZK61 magnesium alloy has higher sliding wear properties after MDF due to higher strength, hardness, and work hardening. Grain refinement affects the wear resistance of the material, but aging increases the hardness and tensile strength and decreases the wear resistance.
    Language English
    Publishing date 2024-01-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma17020523
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Decision model for binary safety management behavior in a supply chain under digital scenarios: A study based on differential game theory.

    He, Binbin / Mei, Qiang / Liu, Suxia / Zhang, Jingjing

    Heliyon

    2024  Volume 10, Issue 5, Page(s) e26471

    Abstract: The purpose of this study is to expand and deepen research in the field of safety production, explore the role of enterprises as decision-making entities in safety production, analyze the role of different types of decision-making behaviors in the ... ...

    Abstract The purpose of this study is to expand and deepen research in the field of safety production, explore the role of enterprises as decision-making entities in safety production, analyze the role of different types of decision-making behaviors in the process of enterprise safety production, and provide certain theoretical guidance for multi-agent decision-making in safety production. By summarizing and comparing the existing dual system of supply chain safety management, this study proposes dividing supply chain safety management into the two categories of safety organization and safety research and development (safety R&D) in the context of digitalization. Differential equations are established to describe a two-level supply chain safety management problem including manufacturers and suppliers. The research results show that, compared with the Nash equilibrium, when there are strong manufacturers involved in safety management cooperation, the manufacturer's safety R&D subsidy to suppliers improves the total revenue of the supply chain. When the manufacturer's safety organization supervision efficiency is high, the Stackelberg equilibrium is lower. It is a Pareto improvement for the manufacturer to supervise the supplier's safety organization to the Nash equilibrium. In the case of dual safety cooperation in the supply chain, when there are strong manufacturers, R&D subsidies have a crowding out effect on the safety organization cooperation. Finally, based on the example analysis, relevant suggestions are put forward for supply chain safety management.
    Language English
    Publishing date 2024-02-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e26471
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Correlation between TCF7L2 and CAPN10 gene polymorphisms and gestational diabetes mellitus in different geographical regions: a meta-analysis.

    He, Jingjing / Zhang, Meng / Ren, Jianhua / Jiang, Xiaolian

    BMC pregnancy and childbirth

    2024  Volume 24, Issue 1, Page(s) 15

    Abstract: Background: The association between TCF7L2 and CAPN10 gene polymorphisms and gestational diabetes mellitus (GDM) has been explored in diverse populations across different geographical regions. Yet, most of these studies have been confined to a limited ... ...

    Abstract Background: The association between TCF7L2 and CAPN10 gene polymorphisms and gestational diabetes mellitus (GDM) has been explored in diverse populations across different geographical regions. Yet, most of these studies have been confined to a limited number of loci, resulting in inconsistent findings. In this study, we conducted a comprehensive review of published literature to identify studies examining the relationship between TCF7L2 and CAPN10 gene polymorphisms and the incidence of GDM in various populations. We specifically focused on five loci that were extensively reported in a large number of publications and performed a meta-analysis.
    Methods: We prioritized the selection of SNPs with well-documented correlations established in existing literature on GDM. We searched eight Chinese and English databases: Cochrane, Elton B. Stephens. Company (EBSCO), Embase, Scopus, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang, and China Science and Technology Journal Database and retrieved all relevant articles published between the inception of the database and July 2022. The Newcastle Ottawa Scale (NOS) was used to evaluate the selected articles, and the odds ratio (OR) was used as the combined effect size index to determine the association between genotypes, alleles, and GDM using different genetic models. Heterogeneity between the studies was quantified and the I
    Results: A total of 39 articles reporting data on 8,795 cases and 16,290 controls were included in the analysis. The frequency of the rs7901695 genotype was statistically significant between cases and controls in the European population (OR = 0.72, 95% CI: 0.65-0.86) and the American population (OR = 0.61, 95% CI: 0.48-0.77). The frequencies of rs12255372, rs7901695, rs290487, and rs2975760 alleles were also considerably different between the cases and controls in the populations analyzed.
    Conclusions: rs7903146, rs12255372, rs7901695, rs290487, and rs2975760 were associated with the incidence of GDM in different populations.
    MeSH term(s) Female ; Humans ; Pregnancy ; Alleles ; Diabetes Mellitus, Type 2 ; Diabetes, Gestational/epidemiology ; Diabetes, Gestational/genetics ; Genetic Predisposition to Disease ; Genotype ; Polymorphism, Single Nucleotide ; Transcription Factor 7-Like 2 Protein/genetics
    Chemical Substances TCF7L2 protein, human ; Transcription Factor 7-Like 2 Protein ; calpain 10 (EC 3.4.22.-)
    Language English
    Publishing date 2024-01-02
    Publishing country England
    Document type Review ; Meta-Analysis ; Journal Article
    ZDB-ID 2059869-5
    ISSN 1471-2393 ; 1471-2393
    ISSN (online) 1471-2393
    ISSN 1471-2393
    DOI 10.1186/s12884-023-06177-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Study on the Damage of Fiber-Reinforced Seawater Sea Sand Concrete by Freezing and Thawing of Seawater.

    Sun, Chuanwu / Wang, Xuezhi / Xin, Ming / He, Jingjing

    Materials (Basel, Switzerland)

    2024  Volume 17, Issue 8

    Abstract: The use of seawater and sea sand as replacements for fresh water and river sand in the preparation of seawater and sea sand concrete can effectively address issues such as high transportation costs, extended construction periods, and resource wastage. ... ...

    Abstract The use of seawater and sea sand as replacements for fresh water and river sand in the preparation of seawater and sea sand concrete can effectively address issues such as high transportation costs, extended construction periods, and resource wastage. Nevertheless, in northern coastal areas, the problem of concrete durability in the complex and changing marine environment is more prominent. Research on the durability of seawater sea sand concrete is beneficial to the widening of its application range. To investigate the impact of glass fiber (GF) and polyvinyl alcohol fiber (PVA) with different blending methods on the seawater freeze-thaw resistance of seawater sea sand concrete (SSC), corresponding specimens were prepared, and seawater freeze-thaw cycling tests were conducted. By adopting the slow-freezing method and combining macro-structure and micro-morphology, the damage mechanism and the deterioration law of fiber-reinforced SSC under seawater freezing and thawing were investigated. The results indicate that, macroscopically, the incorporation of GF and PVA can effectively mitigate the damage to the matrix and reduce the effects of external erosive substances on the rate of strength loss, the rate of mass loss, and the relative dynamic elastic modulus. After 75 cycles, the SSC with a total volume doping of 0.3% and a blending ratio of 1:1 showed a 41.23% and 27.55% reduction in mass loss and strength loss, respectively, and a 29.9% improvement in relative dynamic elastic modulus compared with the basic group. Microscopic analysis reveals that the combined effect of freezing and expansion forces, the expansive substances generated by seawater intrusion into the interior of the matrix, and salt crystallization all weaken the bond between aggregate and mortar, leading to accelerated deterioration of the concrete. The incorporation of fibers enables the matrix to become denser and improves its crack-resistant properties, resulting in a better durability than that of the basic group. The damage prediction model established by the NSGM(1,N) model of gray system theory exhibits high accuracy and is suitable for long-term prediction, accurately predicting the damage of seawater sea sand concrete under seawater freeze-thaw coupling.
    Language English
    Publishing date 2024-04-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma17081910
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Notoginsenoside-R1 ameliorates palmitic acid-induced insulin resistance and oxidative stress in HUVEC via Nrf2/ARE pathway.

    Wang, Jingjing / He, Xun / Lv, Shiwen

    Food science & nutrition

    2023  Volume 11, Issue 12, Page(s) 7791–7802

    Abstract: ... Panax ... ...

    Abstract Panax notoginseng
    Language English
    Publishing date 2023-10-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2703010-6
    ISSN 2048-7177
    ISSN 2048-7177
    DOI 10.1002/fsn3.3696
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  6. Article: A 12 Week Fetus with Anophthalmia, Limb Anomalies and Infratemporal Teratoma.

    Lu, Yu / Zhao, Jing-Jing / He, Ping

    International journal of women's health

    2024  Volume 16, Page(s) 41–46

    Abstract: Background: Microphthalmia is a rare autosomal recessive condition commonly known as Waardenburg anophthalmia syndrome (WAS) or oculo-acromal formation syndrome (MIM#206920).: Case description: Here, we report the case of a woman whose fetal ... ...

    Abstract Background: Microphthalmia is a rare autosomal recessive condition commonly known as Waardenburg anophthalmia syndrome (WAS) or oculo-acromal formation syndrome (MIM#206920).
    Case description: Here, we report the case of a woman whose fetal ultrasonography at 12 weeks of pregnancy revealed multiple fetal abnormalities. These included the absence of the left upper limb, an unclear display of the right orbit, a visible maxillary space, and a round, echoless appearance measuring 4 mm in diameter in the middle of the forehead. There was also a significant echo in the sac wall. The possibility of a frontal meningocele or a proboscis-like nose was considered. The fetus was delivered with absence of the left upper limb, absence of the right eye, a cleft lip on the right side, and a milky white sac with a diameter of 5 mm on the forehead after the pregnancy was terminated at the hospital. Pathological investigation revealed a mature cystic teratoma. The conclusion was microphthalmia with limb anomalies (MLA) after missing limbs, absence of eyes, and cleft lip were input into the Online Mendelian Inheritance in Man database. The case was diagnosed with fetal microphthalmia with limb anomalies and an interfrontal teratoma.
    Conclusion: In this case, the entire exon analysis was not conducted, and as a result, the final diagnosis remains unclear. Based exclusively on the phenotype of the induced fetus, MLA was diagnosed. It is proposed that cases satisfying the requirements for a pathological diagnosis should undergo a pathological examination to establish a definitive diagnosis.
    Language English
    Publishing date 2024-01-10
    Publishing country New Zealand
    Document type Case Reports
    ZDB-ID 2508161-5
    ISSN 1179-1411
    ISSN 1179-1411
    DOI 10.2147/IJWH.S441452
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Serum chemokine IL-8 acts as a biomarker for identifying COVID-19-associated persistent severe acute kidney injury.

    He, Zhi / Liu, Jing-Jing / Ma, Shao-Lei

    Renal failure

    2024  Volume 46, Issue 1, Page(s) 2311316

    Abstract: Objectives: Persistent severe acute kidney injury (PS-AKI) is associated with poor clinical outcomes. Our study attempted to evaluate the diagnostic value of chemokines for early-stage PS-AKI prediction.: Methods: According to the KDIGO criteria, 115 ...

    Abstract Objectives: Persistent severe acute kidney injury (PS-AKI) is associated with poor clinical outcomes. Our study attempted to evaluate the diagnostic value of chemokines for early-stage PS-AKI prediction.
    Methods: According to the KDIGO criteria, 115 COVID-19 patients diagnosed with stage 2/3 AKI were recruited from the intensive care unit between December 2022 and February 2023. Primary clinical outcomes included detecting PS-AKI in the first week (≥ KDIGO stage 2 ≥ 72 h). Cytometric Bead Array was used to detect patient plasma levels (interleukin-8 (IL-8), C-C chemokine ligand 5 (CCL5), chemokine (C-X-C Motif) ligand 9 (CXCL9), and interferon-inducible protein 10 (IP-10)) of chemokines within 24 h of enrollment.
    Results: Of the 115 COVID-19 patients with stage 2/3 AKI, 27 were diagnosed with PS-AKI. Among the four measured chemokines, only the IL-8 level was significantly elevated in the PS-AKI group than in the Non-PS-AKI group. IL-8 was more effective as a biomarker while predicting PS-AKI with an area under the curve of 0.769 (0.675-0.863). This was superior to other biomarkers related to AKI, including serum creatinine. Moreover, plasma IL-8 levels of >32.2 pg/ml on admission could predict PS-AKI risk (sensitivity = 92.6%, specificity = 51.1%). Additionally, the IL-8 level was associated with total protein and IL-6 levels.
    Conclusion: Plasma IL-8 is a promising marker for the early identification of PS-AKI among COVID-19 patients. These findings should be validated in further studies with a larger sample size.
    MeSH term(s) Humans ; Interleukin-8 ; Ligands ; Prospective Studies ; COVID-19/complications ; COVID-19/diagnosis ; Biomarkers ; Acute Kidney Injury/diagnosis ; Acute Kidney Injury/etiology
    Chemical Substances Interleukin-8 ; Ligands ; Biomarkers
    Language English
    Publishing date 2024-02-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 632949-4
    ISSN 1525-6049 ; 0886-022X
    ISSN (online) 1525-6049
    ISSN 0886-022X
    DOI 10.1080/0886022X.2024.2311316
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1331: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: GW9508 ameliorates cognitive dysfunction via autophagy pathway in streptozotocin-induced mouse model of Alzheimer's disease.

    Wang, Yanan / Chen, Jingjing / Wang, Chen / Chen, Tong / He, Ling

    Fundamental & clinical pharmacology

    2024  

    Abstract: Background: G protein-coupled receptor 40 (GPR40) is a potential drug target for Alzheimer's disease (AD), and its agonist GW9508 ameliorates cognitive impairment by intravenous administration.: Objectives: The present study was conducted to ... ...

    Abstract Background: G protein-coupled receptor 40 (GPR40) is a potential drug target for Alzheimer's disease (AD), and its agonist GW9508 ameliorates cognitive impairment by intravenous administration.
    Objectives: The present study was conducted to investigate the efficacy of GW9508 administered peripherally on cognitive dysfunction in streptozotocin (STZ)-induced AD mice.
    Methods: Seventy male ICR mice were randomly divided into seven groups: vehicle sham group, model, Donepezil, GW9508-L, GW9508-M, GW9508-H, and GW1100 + GW9508-H groups, and administered either vehicle (artificial cerebrospinal fluid [aCSF]) or STZ (3 mg/kg in the vehicle) once a day (9:00 a.m.) by intracerebroventricular injection bilaterally on day 1 and day 3, respectively. After 2 weeks of recovery, all mice were given drug treatment. Behavioral experiments were applied to test the recognition and spatial memory of mice, while molecular biology experiments such as Western blot, ELISA, and Nissl staining were used to detect the corresponding changes of signaling pathways.
    Results: Intraperitoneal administration of GW9508 prevented STZ-induced cognitive impairment as well as decreased the level of p-tau and Aβ
    Conclusion: Peripheral administration of GW9508 exhibits neuroprotective effects, and it could be a promising therapy for AD. The neuroprotective mechanism of GW9508 was based on promoting gut-brain peptide secretion, activating Akt/mTOR signal pathway, and regulating neuronal autophagy.
    Language English
    Publishing date 2024-03-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 639134-5
    ISSN 1472-8206 ; 0767-3981
    ISSN (online) 1472-8206
    ISSN 0767-3981
    DOI 10.1111/fcp.13002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2247: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Effects of

    Zhou, Limian / Yin, Xindi / Fang, Bing / He, Jingjing / Zhan, Jing / Zhang, Xiaoxu / Wang, Ran

    Microorganisms

    2024  Volume 12, Issue 3

    Abstract: Probiotics are live microorganisms with immunomodulatory effects in a strain-specific and dose-dependent manner. ...

    Abstract Probiotics are live microorganisms with immunomodulatory effects in a strain-specific and dose-dependent manner.
    Language English
    Publishing date 2024-02-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms12030493
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Network Pharmacology and Experimental Validation to Reveal the Pharmacological Mechanisms of Chongcaoyishen Decoction Against Chronic Kidney Disease.

    Fan, Zhenliang / Chen, Jingjing / Yang, Qiaorui / He, Jiabei

    Frontiers in molecular biosciences

    2022  Volume 9, Page(s) 847812

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2022-03-31
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2814330-9
    ISSN 2296-889X
    ISSN 2296-889X
    DOI 10.3389/fmolb.2022.847812
    Database MEDical Literature Analysis and Retrieval System OnLINE

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