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  1. Article ; Online: In Reply to Dr. Beckta and Dr. Aujla.

    Vachon, Greg / Shah, Chirag / Mohindra, Pranshu / Arnone, Anna / Haffty, Bruce

    International journal of radiation oncology, biology, physics

    2023  Volume 117, Issue 1, Page(s) 282–284

    Language English
    Publishing date 2023-08-11
    Publishing country United States
    Document type Letter
    ZDB-ID 197614-x
    ISSN 1879-355X ; 0360-3016
    ISSN (online) 1879-355X
    ISSN 0360-3016
    DOI 10.1016/j.ijrobp.2023.04.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1218: Show issues Location:
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  2. Article ; Online: Exploring Dyad-Based Communication During Cancer: A Pilot Study.

    Francis, Martha E / Mohindra, Pranshu / Mooney-Doyle, Kim

    Cancer nursing

    2022  Volume 46, Issue 6, Page(s) E384–E393

    Abstract: Background: For patients and intimate partners, the challenge of advanced cancer is often compounded by difficulties in effectively communicating about disease treatment. Relevant evidence-based data are limited, in part because of limitations in ... ...

    Abstract Background: For patients and intimate partners, the challenge of advanced cancer is often compounded by difficulties in effectively communicating about disease treatment. Relevant evidence-based data are limited, in part because of limitations in understanding the dynamics of dyad-based communication.
    Objectives: This pilot study targeted development/feasibility testing of a practical model for assessment of these dynamics in a small group of cancer patients and their intimate partners, with a focus on communication before/after cancer diagnoses, including end-of-life discussions.
    Methods: A descriptive phenomenological design was based on the Bodenmann systemic-transactional model of dyadic coping and on semistructured interviews with 7 dyads. Qualitative data analysis used the Colaizzi 7-step method for narrated text interpretation and identification of emergent themes.
    Results: Patients (median age, 59 years; median intimate partner age, 52 years) had been given a diagnosis of cancer 0 to 6 months before enrollment and were receiving active therapy during participation. Of 534 significant statements analyzed, 2 emergent themes were identified: (1) vulnerable communication during advanced cancer is influenced by preexisting dynamics and complicated by balancing hope/positivity and uncertainty/fear, and (2) communications about end-of-life issues are emotional and influenced by dyad member perceptions about death. A study with a broader racial/demographic representation is planned.
    Conclusion: It is feasible to study dyad communication in the advanced cancer setting, and preliminary data suggest the importance of these dynamics in expression of clinical preferences.
    Implications for practice: Structured interviews with dyads during advanced cancer care can be used to identify specific challenges and inform improved support approaches.
    Language English
    Publishing date 2022-08-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391995-x
    ISSN 1538-9804 ; 0162-220X
    ISSN (online) 1538-9804
    ISSN 0162-220X
    DOI 10.1097/NCC.0000000000001145
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Proposed brachytherapy recommendations (practical implementation, indications, and dose fractionation) during COVID-19 pandemic.

    Mohindra, Pranshu / Beriwal, Sushil / Kamrava, Mitchell

    Brachytherapy

    2020  Volume 19, Issue 4, Page(s) 390–400

    Keywords covid19
    Language English
    Publishing date 2020-05-01
    Publishing country United States
    Document type Editorial
    ZDB-ID 2098608-7
    ISSN 1873-1449 ; 1538-4721
    ISSN (online) 1873-1449
    ISSN 1538-4721
    DOI 10.1016/j.brachy.2020.04.009
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    Zs.A 6116: Show issues Location:
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  4. Article ; Online: Surgery for early-stage small cell lung cancer: is it worth it?

    Vyfhuis, Melissa A L / Mohindra, Pranshu / Simone, Charles B

    Mediastinum (Hong Kong, China)

    2019  Volume 3, Page(s) 25

    Language English
    Publishing date 2019-06-14
    Publishing country China
    Document type Editorial ; Comment
    ISSN 2522-6711
    ISSN (online) 2522-6711
    DOI 10.21037/med.2019.06.01
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  5. Article: Advances in radiation therapy for thoracic malignancies.

    Simone, Charles B / Badiyan, Shahed N / Mohindra, Pranshu

    Journal of thoracic disease

    2018  Volume 10, Issue Suppl 21, Page(s) S2431–S2436

    Language English
    Publishing date 2018-09-06
    Publishing country China
    Document type Journal Article
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd.2018.08.10
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  6. Article: Advances in management of locally advanced cervical cancer.

    Musunuru, Hima Bindu / Pifer, Phillip M / Mohindra, Pranshu / Albuquerque, Kevin / Beriwal, Sushil

    The Indian journal of medical research

    2022  Volume 154, Issue 2, Page(s) 248–261

    Abstract: Globally, cervical cancer has the fourth highest cancer incidence and mortality in women. Cervical cancer is unique because it has effective prevention, screening, and treatment options. This review discusses the current cervical cancer advances with a ... ...

    Abstract Globally, cervical cancer has the fourth highest cancer incidence and mortality in women. Cervical cancer is unique because it has effective prevention, screening, and treatment options. This review discusses the current cervical cancer advances with a focus on locally advanced cervical cancer. Topics discussed include diagnostic imaging principles, surgical management with adjuvant therapy and definitive concurrent chemoradiotherapy. Emphasis is given on current advances and future research directions in radiation therapy (RT) with an emphasis on three-dimensional brachytherapy, intensity-modulated RT, image-guided RT, proton RT and hyperthermia.
    MeSH term(s) Brachytherapy/methods ; Chemoradiotherapy/methods ; Combined Modality Therapy ; Female ; Humans ; Radiotherapy, Intensity-Modulated/methods ; Uterine Cervical Neoplasms/diagnostic imaging ; Uterine Cervical Neoplasms/epidemiology
    Language English
    Publishing date 2022-02-10
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 390883-5
    ISSN 0971-5916 ; 0019-5340
    ISSN 0971-5916 ; 0019-5340
    DOI 10.4103/ijmr.IJMR_1047_20
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    Ua VI Zs.143: Show issues Location:
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  7. Article ; Online: Complications of intracavitary brachytherapy for gynecologic cancers and their management: A comprehensive review.

    Glaser, Scott M / Mohindra, Pranshu / Mahantshetty, Umesh / Beriwal, Sushil

    Brachytherapy

    2021  Volume 20, Issue 5, Page(s) 984–994

    Abstract: Intracavitary gynecologic brachytherapy in the form of tandem-based brachytherapy and vaginal cylinder-based brachytherapy represents a fundamental component of the treatment of women with cervical or uterine cancer due to the ability to deliver a ... ...

    Abstract Intracavitary gynecologic brachytherapy in the form of tandem-based brachytherapy and vaginal cylinder-based brachytherapy represents a fundamental component of the treatment of women with cervical or uterine cancer due to the ability to deliver a therapeutic dose of radiation with sharp dose falloff. This results in highly effective treatment in terms of oncologic outcomes with an overall favorable toxicity profile. Still, complications and side effects of brachytherapy do exist. While advances in brachytherapy techniques have led to a significant decrease in the rates of toxicity, a thorough understanding of the potential complications is crucial to ensuring optimal outcomes for women with gynecologic cancer undergoing brachytherapy. Use of equivalent dose at 2 Gy per fraction (EQD2) models has allowed incorporation of external beam radiotherapy dose to the brachytherapy dose leading to development of consolidated dose constraints for organs-at-risk in the modern era. This manuscript offers a comprehensive review of potential complications associated with intracavitary brachytherapy for gynecologic cancer including predictive factors, mitigation tactics, and management strategies.
    MeSH term(s) Brachytherapy/methods ; Female ; Genital Neoplasms, Female/radiotherapy ; Humans ; Organs at Risk ; Radiotherapy Dosage ; Uterine Cervical Neoplasms/radiotherapy
    Language English
    Publishing date 2021-01-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2098608-7
    ISSN 1873-1449 ; 1538-4721
    ISSN (online) 1873-1449
    ISSN 1538-4721
    DOI 10.1016/j.brachy.2020.11.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6116: Show issues Location:
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  8. Article: Clinical Outcomes of Intensity Modulated Proton Therapy Reirradiation for Gynecologic Malignancies.

    Pollock, Ariel E / Risher, Hunter / Berger, Melanie / Roque, Dana M / Rao, Gautam / Nichols, Elizabeth M / Mohindra, Pranshu

    Advances in radiation oncology

    2023  Volume 8, Issue 4, Page(s) 101191

    Abstract: Purpose: Pelvic reirradiation (re-RT) for patients with gynecologic cancers remains a challenge because of toxicity concerns. Given the dosimetric advantages of proton therapy, we aimed to assess oncologic and toxicity outcomes of patients with re-RT to ...

    Abstract Purpose: Pelvic reirradiation (re-RT) for patients with gynecologic cancers remains a challenge because of toxicity concerns. Given the dosimetric advantages of proton therapy, we aimed to assess oncologic and toxicity outcomes of patients with re-RT to the pelvis/abdomen with intensity modulated proton therapy (IMPT) for gynecologic cancers.
    Methods and materials: We performed a retrospective analysis of all patients with gynecologic cancer treated at a single institution between 2015 and 2021 with IMPT re-RT. Patients were included for analysis if the IMPT plan had at least partial overlap with the treated volume of a previous radiation treatment.
    Results: A total of 29 patients were included for analysis, with 30 total courses of re-RT. The majority of patients had been treated previously with conventional fractionation to a median dose of 49.2 Gy (30-61.6 Gy). With a median follow-up of 23 months, 1-year local control was 83.5% and overall survival was 65.7%. Three patients (10%) developed acute and late grade 3 toxicity. One-year freedom from late grade 3+ toxicity was 96.3%.
    Conclusions: This is the first complete analysis of clinical outcomes for re-RT with IMPT for gynecologic malignancies. We demonstrate excellent local control and acceptable acute and late toxicity. IMPT should strongly be considered for treatments requiring re-RT for gynecologic malignancies.
    Language English
    Publishing date 2023-02-25
    Publishing country United States
    Document type Journal Article
    ISSN 2452-1094
    ISSN 2452-1094
    DOI 10.1016/j.adro.2023.101191
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  9. Article ; Online: Stereotactic Body Radiation Therapy versus Thermal Ablation for Early Stage Non-Small Cell Lung Cancer.

    Vyfhuis, Melissa A L / Mohindra, Pranshu / Simone, Charles B

    Radiology

    2019  Volume 290, Issue 2, Page(s) 574–575

    MeSH term(s) Carcinoma, Non-Small-Cell Lung/surgery ; Humans ; Lung Neoplasms/surgery ; Radiosurgery ; Small Cell Lung Carcinoma ; Survival Rate
    Language English
    Publishing date 2019-01-01
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.2018182310
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    Ue I Zs.106: Show issues Location:
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  10. Article: Serum microRNA guiding personalized radiation therapy in non-small cell lung cancer.

    Amin, Neha P / Mohindra, Pranshu / Jabbour, Salma K

    Journal of thoracic disease

    2018  Volume 10, Issue Suppl 33, Page(s) S4108–S4112

    Language English
    Publishing date 2018-10-22
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd.2018.09.143
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