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  1. Book ; Online ; E-Book: Therapy in pediatric dermatology

    Teng, Joyce M.C. / Marqueling, Ann L. / Benjamin, Latanya T.

    management of pediatric skin disease

    2017  

    Author's details Joyce M.C. Teng, Ann L. Marqueling, Latanya T. Benjamin, editors
    Keywords Infant ; Child ; Adolescent ; Skin Diseases / therapy ; Kind ; Hautkrankheit ; Therapie
    Subject Medizinische Behandlung ; Behandlung ; Krankenbehandlung ; Dermatose ; Haut ; Hauterkrankung ; Hautkrankheiten ; Kindheit ; Kindesalter ; Kindschaft ; Kinder
    Language English
    Size 1 Online-Ressource (XVII, 466 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019470220
    ISBN 978-3-319-43630-2 ; 9783319436289 ; 3-319-43630-9 ; 3319436287
    DOI 10.1007/978-3-319-43630-2
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Central Nervous System Xanthoma Disseminatum: Response to 2CdA in an Adolescent.

    DeMoss, Patrick / Tang, Nancy / Yeom, Kristen / Chiang, Audris / Marqueling, Ann L / Jeng, Michael R

    Case reports in pediatrics

    2022  Volume 2022, Page(s) 9906668

    Abstract: Xanthoma disseminatum is a normolipemic non-Langerhans cell histiocytosis characterized by red-brown rubbery papules of the skin which coalesce into plaque-like lesions with symmetric involvement of face, flexor, and intertriginous areas. Less commonly, ... ...

    Abstract Xanthoma disseminatum is a normolipemic non-Langerhans cell histiocytosis characterized by red-brown rubbery papules of the skin which coalesce into plaque-like lesions with symmetric involvement of face, flexor, and intertriginous areas. Less commonly, xanthoma disseminatum may affect mucosal linings, abdominal organs, and the central nervous system, leading to endocrinopathies. We report a 12-year-old adolescent with mucosal, central nervous system, and painful cutaneous lesions, further complicated by diabetes insipidus and amenorrhea. Treatment with 2-chlorodeoxyadenosine led to relief of pain and significant improvement of mucosal, central nervous system, and cutaneous lesions, with subsequent restoration of menstrual cycles.
    Language English
    Publishing date 2022-07-22
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2659094-3
    ISSN 2090-6811 ; 2090-6803
    ISSN (online) 2090-6811
    ISSN 2090-6803
    DOI 10.1155/2022/9906668
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Systemic treatments for severe pediatric psoriasis: a practical approach.

    Marqueling, Ann L / Cordoro, Kelly M

    Dermatologic clinics

    2013  Volume 31, Issue 2, Page(s) 267–288

    Abstract: Severe psoriasis is uncommon in children, but when it occurs, can be physically, emotionally and socially disabling. Systemic treatments such as phototherapy, acitretin, methotrexate and cyclosporine have been used to manage severe pediatric psoriasis ... ...

    Abstract Severe psoriasis is uncommon in children, but when it occurs, can be physically, emotionally and socially disabling. Systemic treatments such as phototherapy, acitretin, methotrexate and cyclosporine have been used to manage severe pediatric psoriasis for decades. Newer biologic agents have demonstrated their effectiveness in adult psoriasis and are accumulating promising data in children. This article discusses the use of these treatments including their indications, efficacy, adverse effects, and monitoring requirements. The aim is to provide practical, clinically relevant information regarding the use of these medications alone and in various combinations based on available evidence and cumulative experience.
    MeSH term(s) Biological Products/therapeutic use ; Child ; Child, Preschool ; Dermatologic Agents/therapeutic use ; Drug Therapy, Combination ; Humans ; Phototherapy/methods ; Psoriasis/psychology ; Psoriasis/therapy ; Severity of Illness Index
    Chemical Substances Biological Products ; Dermatologic Agents
    Language English
    Publishing date 2013-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 82798-8
    ISSN 1558-0520 ; 0733-8635
    ISSN (online) 1558-0520
    ISSN 0733-8635
    DOI 10.1016/j.det.2012.12.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Therapy in pediatric dermatology

    Teng, Joyce M. C / Marqueling, Ann L / Benjamin, Latanya T

    management of pediatric skin disease

    2017  

    Author's details Joyce M.C. Teng, Ann L. Marqueling, Latanya T. Benjamin, editors
    MeSH term(s) Skin Diseases/therapy ; Infant ; Child ; Adolescent
    Language English
    Size xvii, 466 pages :, illustrations ;, 29 cm
    Document type Book
    ISBN 9783319436289 ; 3319436287 ; 9783319436302 ; 3319436309
    Database Catalogue of the US National Library of Medicine (NLM)

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  5. Article ; Online: A Hyperpigmented Reticular Rash in a Patient on Peritoneal Dialysis.

    South, Andrew M / Crispin, Milene K / Marqueling, Ann L / Sutherland, Scott M

    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis

    2016  Volume 36, Issue 6, Page(s) 699–700

    Abstract: Chronically ill patients often develop uncommon exam findings. A 16-year-old female with end-stage renal disease secondary to immune complex-mediated glomerulonephritis on peritoneal dialysis (PD) developed a pruritic, hyperpigmented reticular rash on ... ...

    Abstract Chronically ill patients often develop uncommon exam findings. A 16-year-old female with end-stage renal disease secondary to immune complex-mediated glomerulonephritis on peritoneal dialysis (PD) developed a pruritic, hyperpigmented reticular rash on her abdomen, sparing the PD catheter insertion site. The rash appeared approximately 6 weeks after initiating PD. She used a heating pad nightly during PD for dialysis drain pain. Testing for systemic and autoimmune disease was negative. She was referred to dermatology, where the diagnosis of erythema ab igne (EAI), a well-described but less well-known hyperpigmented reticular cutaneous eruption caused by chronic exposure to low levels of infrared heat, was confirmed. The eruption is typically painless but is often pruritic. Common sources of heat include fires, stoves, portable heaters, heating pads, and laptop computers. The association between EAI and PD is unknown. Our patient discontinued the heating pad and her rash resolved.
    MeSH term(s) Adolescent ; Erythema/etiology ; Erythema/physiopathology ; Female ; Follow-Up Studies ; Hot Temperature/adverse effects ; Hot Temperature/therapeutic use ; Humans ; Hyperpigmentation/etiology ; Hyperpigmentation/physiopathology ; Kidney Failure, Chronic/diagnosis ; Kidney Failure, Chronic/therapy ; Pain/etiology ; Pain/physiopathology ; Peritoneal Dialysis/adverse effects ; Peritoneal Dialysis/methods ; Remission, Spontaneous ; Risk Assessment ; Treatment Outcome
    Language English
    Publishing date 2016-11-23
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 645010-6
    ISSN 1718-4304 ; 0896-8608
    ISSN (online) 1718-4304
    ISSN 0896-8608
    DOI 10.3747/pdi.2016.00042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Next-generation sequencing confirms T-cell clonality in a subset of pediatric pityriasis lichenoides.

    Raghavan, Shyam S / Wang, Jennifer Y / Gru, Alejandro A / Marqueling, Ann L / Teng, Joyce M C / Brown, Ryanne A / Novoa, Roberto A / Kim, Youn / Zehnder, James / Zhang, Bing Melody / Rieger, Kerri E

    Journal of cutaneous pathology

    2021  Volume 49, Issue 3, Page(s) 252–260

    Abstract: Background: Pityriasis lichenoides (PL) is a papulosquamous disease that affects both adults and children. Previous studies have shown a subset of this entity to have clonal T-cell populations via PCR-based assays. In this study, we sought to implement ... ...

    Abstract Background: Pityriasis lichenoides (PL) is a papulosquamous disease that affects both adults and children. Previous studies have shown a subset of this entity to have clonal T-cell populations via PCR-based assays. In this study, we sought to implement next-generation sequencing (NGS) as a more sensitive and specific test to examine for T-cell clonality within the pediatric population.
    Methods: We identified 18 biopsy specimens from 12 pediatric patients with clinical and histopathologic findings compatible with PL. Patient demographics, clinical features, management, and histopathologic findings were reviewed. All specimens were analyzed for clonality with NGS of T-cell receptor beta (TRB) and gamma (TRG) genes.
    Results: Of the 12 patients, 9 (75%) had complete resolution of lesions at the time of data collection (mean follow-up 31 months). The remaining three patients significantly improved with methotrexate (with or without acitretin). Interestingly, 7 of 12 patients (58%) and 9 of 17 biopsy specimens (53%) showed evidence of T-cell clonality. Two patients showed matching TRB clones from different anatomic sites.
    Conclusions: T-cell clonality is a common finding in PL, probably representing a "reactive clonality" rather than a true lymphoproliferative disorder. Clonality alone cannot be used as a means to distinguish PL from lymphomatoid papulosis or cutaneous lymphoma.
    MeSH term(s) Adolescent ; Child ; Child, Preschool ; Cloning, Molecular ; Female ; Genes, T-Cell Receptor beta/genetics ; Genes, T-Cell Receptor gamma/genetics ; High-Throughput Nucleotide Sequencing ; Humans ; Male ; Pityriasis Lichenoides/genetics
    Language English
    Publishing date 2021-10-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 187078-6
    ISSN 1600-0560 ; 0303-6987
    ISSN (online) 1600-0560
    ISSN 0303-6987
    DOI 10.1111/cup.14143
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1043: Show issues Location:
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  7. Article ; Online: Cutaneous Neonatal Lupus Arising in an Infant Conceived From an Oocyte Donation Pregnancy.

    Chiou, Albert Sean / Sun, Grace / Kim, Jinah / Wang, Kevin Chun-Kai / Marqueling, Ann L

    JAMA dermatology

    2016  Volume 152, Issue 7, Page(s) 846–847

    Language English
    Publishing date 2016-07-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701761-8
    ISSN 2168-6084 ; 2168-6068
    ISSN (online) 2168-6084
    ISSN 2168-6068
    DOI 10.1001/jamadermatol.2016.0001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Well-Appearing Newborn With a Vesiculobullous Rash at Birth.

    Stewart, Sarah E / Lin, Jody L / Everhart, Jennifer L / Pham, Trung H / Marqueling, Ann L / Rieger, Kerri E / Hilgenberg, Sarah L

    Pediatrics

    2018  Volume 141, Issue 3

    Abstract: A term, appropriate-for-gestational-age, male infant born via normal spontaneous vaginal delivery presented at birth with a full-body erythematous, vesiculobullous rash. He was well-appearing with normal vital signs and hypoglycemia that quickly resolved. ...

    Abstract A term, appropriate-for-gestational-age, male infant born via normal spontaneous vaginal delivery presented at birth with a full-body erythematous, vesiculobullous rash. He was well-appearing with normal vital signs and hypoglycemia that quickly resolved. His father had a history of herpes labialis. His mother had an episode of herpes zoster during pregnancy and a prolonged rupture of membranes that was adequately treated. The patient underwent a sepsis workup, including 2 attempted but unsuccessful lumbar punctures, and was started on broad-spectrum antibiotics and acyclovir, given concerns about bacterial or viral infection. The rash evolved over the course of several days. Subsequent workup, with particular attention to his history and presentation, led to his diagnosis.
    MeSH term(s) Diagnosis, Differential ; Drug Therapy, Combination ; Exanthema/etiology ; Humans ; Infant, Newborn ; Male ; Mastocytosis, Cutaneous/diagnosis ; Mastocytosis, Cutaneous/drug therapy ; Skin Diseases, Infectious/diagnosis ; Skin Diseases, Vesiculobullous/etiology
    Language English
    Publishing date 2018-02-06
    Publishing country United States
    Document type Case Reports ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 207677-9
    ISSN 1098-4275 ; 0031-4005
    ISSN (online) 1098-4275
    ISSN 0031-4005
    DOI 10.1542/peds.2017-0236
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 357: Show issues

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  9. Article: Depression and suicidal behavior in acne patients treated with isotretinoin: a systematic review.

    Marqueling, Ann L / Zane, Lee T

    Seminars in cutaneous medicine and surgery

    2007  Volume 26, Issue 4, Page(s) 210–220

    Abstract: Isotretinoin (13-cis retinoic acid) is an effective treatment for severe cystic or recalcitrant acne vulgaris; however, concerns have been raised regarding its potential association with depression and suicidal behavior. We sought to explore the proposed ...

    Abstract Isotretinoin (13-cis retinoic acid) is an effective treatment for severe cystic or recalcitrant acne vulgaris; however, concerns have been raised regarding its potential association with depression and suicidal behavior. We sought to explore the proposed relationship between isotretinoin use and the risk of depression and attempted and completed suicide in patients with acne vulgaris by performing a systematic literature search for studies reporting primary data on depression and suicidal behavior in patients treated with isotretinoin for acne vulgaris. Nine studies met the qualifying criteria for our analysis. Rates of depression among isotretinoin users ranged from 1% to 11% across studies, with similar rates in oral antibiotic control groups. Overall, studies comparing depression before and after treatment did not show a statistically significant increase in depression diagnoses or depressive symptoms. Some, in fact, demonstrated a trend toward fewer or less severe depressive symptoms after isotretinoin therapy. This decrease was particularly evident in patients with pretreatment scores in the moderate or clinical depression range. No correlation between isotretinoin use and suicidal behavior was reported, although only one retrospective study presented data on this topic. Although the current literature does not support a causative association between isotretinoin use and depression, there are important limitations to many of the studies. The available data on suicidal behavior during isotretinoin treatment are insufficient to establish a meaningful causative association.
    MeSH term(s) Acneiform Eruptions/drug therapy ; Acneiform Eruptions/epidemiology ; Acneiform Eruptions/psychology ; Causality ; Depression/chemically induced ; Depression/epidemiology ; Humans ; Isotretinoin/adverse effects ; Isotretinoin/therapeutic use ; Psychiatric Status Rating Scales ; Risk Assessment ; Risk Factors ; Suicide/statistics & numerical data
    Chemical Substances Isotretinoin (EH28UP18IF)
    Language English
    Publishing date 2007-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1355511-x
    ISSN 1558-0768 ; 1085-5629
    ISSN (online) 1558-0768
    ISSN 1085-5629
    DOI 10.1016/j.sder.2008.03.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1754: Show issues Location:
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  10. Article ; Online: Propranolol and infantile hemangiomas four years later: a systematic review.

    Marqueling, Ann L / Oza, Vikash / Frieden, Ilona J / Puttgen, Katherine B

    Pediatric dermatology

    2013  Volume 30, Issue 2, Page(s) 182–191

    Abstract: To systematically review the literature evaluating efficacy and adverse events of propranolol treatment for infantile hemangiomas, we searched the MEDLINE and Cochrane databases for all studies examining the response of infantile hemangiomas (IHs) to ... ...

    Abstract To systematically review the literature evaluating efficacy and adverse events of propranolol treatment for infantile hemangiomas, we searched the MEDLINE and Cochrane databases for all studies examining the response of infantile hemangiomas (IHs) to propranolol published between June 12, 2008, and June 15, 2012. Forty-one studies with 1,264 patients were included; 74% of patients were female and approximately 30% had received other treatments before propranolol. Propranolol was initiated at a mean age of 6.6 months at a mean dose of 2.1 mg/kg/day and for a mean treatment duration of 6.4 months. The response rate for patients with IHs treated with propranolol was 98% (range 82%-100%), with response rate defined as any improvement with propranolol. Treatment response rates were comparable for studies evaluating IHs at specific sites, such as periorbital IHs. Studies that followed patients after treatment completion reported IH rebound growth in 17% of patients. There were 371 adverse events reported in 1,189 patients. The most common adverse events were changes in sleep (n = 136) and acrocyanosis (n = 61). Serious adverse events were rare, with reports of symptomatic hypotension in five patients, hypoglycemia in four, and symptomatic bradycardia in one. This systematic review of 1,264 patients treated with propranolol for IHs showed a high rate of efficacy and a low rate of serious adverse events.
    MeSH term(s) Adrenergic beta-Antagonists/adverse effects ; Adrenergic beta-Antagonists/therapeutic use ; Female ; Hemangioma/drug therapy ; Humans ; Infant ; Male ; Propranolol/adverse effects ; Propranolol/therapeutic use ; Skin Neoplasms/drug therapy ; Treatment Outcome
    Chemical Substances Adrenergic beta-Antagonists ; Propranolol (9Y8NXQ24VQ)
    Language English
    Publishing date 2013-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.12089
    Database MEDical Literature Analysis and Retrieval System OnLINE

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