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  1. Article ; Online: Polarization patterns of light enable geolocalization in oceans.

    Wang, Lihong V

    Light, science & applications

    2023  Volume 12, Issue 1, Page(s) 240

    Abstract: The deep ocean, characterized by its immense depths and absence of global positioning system (GPS) functionality, presents considerable challenges for search and rescue missions. Inspired by the geolocalization capabilities of migratory marine animals, ... ...

    Abstract The deep ocean, characterized by its immense depths and absence of global positioning system (GPS) functionality, presents considerable challenges for search and rescue missions. Inspired by the geolocalization capabilities of migratory marine animals, Bai et al. present a novel method for underwater geolocalization using the polarization patterns of light in the underwater environment. Emulating a sextant using these underwater polarization patterns, the study determines geolocation in underwater settings. Despite prior skepticism, even in low-visibility waters, these patterns, learned through a deep neural network, provide geolocation accuracies of 55 km at 8 m and 255 km at 50 m. This pioneering approach offers implications for search and rescue and hints at navigation mechanisms in marine animals.
    Language English
    Publishing date 2023-09-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2662628-7
    ISSN 2047-7538 ; 2047-7538
    ISSN (online) 2047-7538
    ISSN 2047-7538
    DOI 10.1038/s41377-023-01279-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: Photoacoustic imaging and spectroscopy

    Wang, Lihong V.

    (Optical science and engineering ; 144)

    2009  

    Author's details ed. by Lihong V. Wang
    Series title Optical science and engineering ; 144
    Collection
    Keywords Optoacoustic spectroscopy ; Imaging systems
    Subject code 621.36
    Language English
    Size XX, 499 S. : Ill., graph. Darst., 28cm
    Publisher CRC Press
    Publishing place Boca Raton, Fla. u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT015785692
    ISBN 1-4200-5991-2 ; 978-1-4200-5991-5 ; 9780415801102 ; 0415801109
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2009 A 1292 order for loan Magazin

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  3. Article ; Online: Single-Shot Reconfigurable Femtosecond Imaging of Ultrafast Optical Dynamics.

    Wang, Peng / Wang, Lihong V

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    2023  Volume 10, Issue 13, Page(s) e2207222

    Abstract: Understanding ultrafast dynamics in the femtosecond timescale plays a pivotal role in fundamental research and technology innovation. Spatiotemporal observation of those events in real-time requires imaging speeds greater than ... ...

    Abstract Understanding ultrafast dynamics in the femtosecond timescale plays a pivotal role in fundamental research and technology innovation. Spatiotemporal observation of those events in real-time requires imaging speeds greater than 10
    Language English
    Publishing date 2023-03-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2808093-2
    ISSN 2198-3844 ; 2198-3844
    ISSN (online) 2198-3844
    ISSN 2198-3844
    DOI 10.1002/advs.202207222
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Single-shot photoacoustic imaging with single-element transducer through a spatiotemporal encoder.

    Zhao, Yanyu / Wang, Lihong V

    Journal of biomedical optics

    2023  Volume 28, Issue 4, Page(s) 46004

    Abstract: Significance: Current photoacoustic (PA) imaging modalities typically require either serial detection with a single-element transducer or parallel detections with an ultrasonic array, indicating a dilemma between system cost and imaging throughput. PA ... ...

    Abstract Significance: Current photoacoustic (PA) imaging modalities typically require either serial detection with a single-element transducer or parallel detections with an ultrasonic array, indicating a dilemma between system cost and imaging throughput. PA topography through ergodic relay (PATER) was recently developed to address this bottleneck. However, PATER requires object-specific calibration due to varied boundary condition and must be recalibrated through pointwise scanning for each object before measurements, which is time-consuming and severely limits practical application.
    Aim: We aim to develop a new single-shot PA imaging technique that only requires a one-time calibration for imaging different objects using a single-element transducer.
    Approach: We develop an imaging method, PA imaging through a spatiotemporal encoder (PAISE), to address the above issue. The spatial information is effectively coded into unique temporal features by the spatiotemporal encoder, which allows for compressive image reconstruction. An ultrasonic waveguide is proposed as a critical element to guide the PA waves from the object into the prism, which effectively accounts for the varied boundary condition of different objects. We further add irregular-shaped edges on the prism to introduce randomized internal reflections and further facilitate the scrambling of acoustic waves.
    Results: The proposed technique is validated through comprehensive numerical simulations and experiments, and it is demonstrated that PAISE can successfully overcome the changed boundary condition and can image different samples given a single calibration.
    Conclusions: The proposed PAISE technique is capable of single-shot widefield PA imaging with a single-element transducer and does not require sample-specific calibration, which successfully overcomes the major limitation of previous PATER technology.
    MeSH term(s) Photoacoustic Techniques/methods ; Diagnostic Imaging ; Image Processing, Computer-Assisted/methods ; Spectrum Analysis ; Transducers ; Phantoms, Imaging
    Language English
    Publishing date 2023-04-13
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1309154-2
    ISSN 1560-2281 ; 1083-3668
    ISSN (online) 1560-2281
    ISSN 1083-3668
    DOI 10.1117/1.JBO.28.4.046004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4699: Show issues Location:
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  5. Book: Biomedical optics

    Wang, Lihong V. / Wu, Hsin-i

    principles and imaging

    2007  

    Author's details Lihong V. Wang ; Hsin-I Wu
    Keywords Optics ; Light ; Models, Theoretical ; Diagnostic Imaging / methods ; Tomography, Optical / methods
    Language English
    Size XIV, 362 S. : graph. Darst.
    Publisher Wiley-Interscience
    Publishing place Hoboken, NJ
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT015100565
    ISBN 0-471-74304-6 ; 978-0-471-74304-0
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2007 A 3502 order for loan Magazin

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  6. Article: Data-driven system matrix manipulation enabling fast functional imaging and intra-image nonrigid motion correction in tomography.

    Hu, Peng / Tong, Xin / Lin, Li / Wang, Lihong V

    bioRxiv : the preprint server for biology

    2024  

    Abstract: Tomographic imaging modalities are described by large system matrices. Sparse sampling and tissue motion degrade system matrix and image quality. Various existing techniques improve the image quality without correcting the system matrices. Here, we ... ...

    Abstract Tomographic imaging modalities are described by large system matrices. Sparse sampling and tissue motion degrade system matrix and image quality. Various existing techniques improve the image quality without correcting the system matrices. Here, we compress the system matrices to improve computational efficiency (e.g., 42 times) using singular value decomposition and fast Fourier transform. Enabled by the efficiency, we propose (1) fast sparsely sampling functional imaging by incorporating a densely sampled prior image into the system matrix, which maintains the critical linearity while mitigating artifacts and (2) intra-image nonrigid motion correction by incorporating the motion as subdomain translations into the system matrix and reconstructing the translations together with the image iteratively. We demonstrate the methods in 3D photoacoustic computed tomography with significantly improved image qualities and clarify their applicability to X-ray CT and MRI or other types of imperfections due to the similarities in system matrices.
    Language English
    Publishing date 2024-01-08
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2024.01.07.574504
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Shining Future of Biomedical Optics

    Wang, Lihong

    Journal of biomedical optics

    2017  Volume 22, Issue 10, Page(s) 100101

    Abstract: Lihong V. Wang summarizes his tenure as Editor-in-Chief of the Journal of Biomedical Optics and ...

    Abstract Lihong V. Wang summarizes his tenure as Editor-in-Chief of the Journal of Biomedical Optics and introduces his successor, Brian Pogue, who will assume the role in January 2018.
    Language English
    Publishing date 2017-10-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1309154-2
    ISSN 1560-2281 ; 1083-3668
    ISSN (online) 1560-2281
    ISSN 1083-3668
    DOI 10.1117/1.JBO.22.10.100101
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    Zs.A 4699: Show issues Location:
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  8. Article ; Online: The emerging role of photoacoustic imaging in clinical oncology.

    Lin, Li / Wang, Lihong V

    Nature reviews. Clinical oncology

    2022  Volume 19, Issue 6, Page(s) 365–384

    Abstract: Clinical oncology can benefit substantially from imaging technologies that reveal physiological characteristics with multiscale observations. Complementing conventional imaging modalities, photoacoustic imaging (PAI) offers rapid imaging (for example, ... ...

    Abstract Clinical oncology can benefit substantially from imaging technologies that reveal physiological characteristics with multiscale observations. Complementing conventional imaging modalities, photoacoustic imaging (PAI) offers rapid imaging (for example, cross-sectional imaging in real time or whole-breast scanning in 10-15 s), scalably high levels of spatial resolution, safe operation and adaptable configurations. Most importantly, this novel imaging modality provides informative optical contrast that reveals details on anatomical, functional, molecular and histological features. In this Review, we describe the current state of development of PAI and the emerging roles of this technology in cancer screening, diagnosis and therapy. We comment on the performance of cutting-edge photoacoustic platforms, and discuss their clinical applications and utility in various clinical studies. Notably, the clinical translation of PAI is accelerating in the areas of macroscopic and mesoscopic imaging for patients with breast or skin cancers, as well as in microscopic imaging for histopathology. We also highlight the potential of future developments in technological capabilities and their clinical implications, which we anticipate will lead to PAI becoming a desirable and widely used imaging modality in oncological research and practice.
    MeSH term(s) Diagnostic Imaging ; Early Detection of Cancer ; Humans ; Medical Oncology ; Photoacoustic Techniques/methods
    Language English
    Publishing date 2022-03-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2491410-1
    ISSN 1759-4782 ; 1759-4774
    ISSN (online) 1759-4782
    ISSN 1759-4774
    DOI 10.1038/s41571-022-00615-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6029: Show issues Location:
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    Zs.MG 103: Show issues

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  9. Article ; Online: Location-Dependent Spatiotemporal Antialiasing in Photoacoustic Computed Tomography.

    Hu, Peng / Li, Lei / Wang, Lihong V

    IEEE transactions on medical imaging

    2023  Volume 42, Issue 4, Page(s) 1210–1224

    Abstract: Photoacoustic computed tomography (PACT) images optical absorption contrast by detecting ultrasonic waves induced by optical energy deposition in materials such as biological tissues. An ultrasonic transducer array or its scanning equivalent is used to ... ...

    Abstract Photoacoustic computed tomography (PACT) images optical absorption contrast by detecting ultrasonic waves induced by optical energy deposition in materials such as biological tissues. An ultrasonic transducer array or its scanning equivalent is used to detect ultrasonic waves. The spatial distribution of the transducer elements must satisfy the spatial Nyquist criterion; otherwise, spatial aliasing occurs and causes artifacts in reconstructed images. The spatial Nyquist criterion poses different requirements on the transducer elements' distributions for different locations in the image domain, which has not been studied previously. In this research, we elaborate on the location dependency through spatiotemporal analysis and propose a location-dependent spatiotemporal antialiasing method. By applying this method to PACT in full-ring array geometry, we effectively mitigate aliasing artifacts with minimal effects on image resolution in both numerical simulations and in vivo experiments.
    MeSH term(s) Artifacts ; Spatio-Temporal Analysis ; Tomography, X-Ray Computed/instrumentation ; Tomography, X-Ray Computed/methods ; Tomography, X-Ray Computed/standards ; Breast/diagnostic imaging ; Humans ; Image Processing, Computer-Assisted ; Algorithms ; Photoacoustic Techniques/methods ; Photoacoustic Techniques/standards ; Computer Simulation ; Phantoms, Imaging ; Female ; Reproducibility of Results
    Language English
    Publishing date 2023-04-03
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 622531-7
    ISSN 1558-254X ; 0278-0062
    ISSN (online) 1558-254X
    ISSN 0278-0062
    DOI 10.1109/TMI.2022.3225565
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2546: Show issues Location:
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  10. Article: Photoacoustic computed tomography for functional human brain imaging [Invited].

    Na, Shuai / Wang, Lihong V

    Biomedical optics express

    2021  Volume 12, Issue 7, Page(s) 4056–4083

    Abstract: The successes of magnetic resonance imaging and modern optical imaging of human brain function have stimulated the development of complementary modalities that offer molecular specificity, fine spatiotemporal resolution, and sufficient penetration ... ...

    Abstract The successes of magnetic resonance imaging and modern optical imaging of human brain function have stimulated the development of complementary modalities that offer molecular specificity, fine spatiotemporal resolution, and sufficient penetration simultaneously. By virtue of its rich optical contrast, acoustic resolution, and imaging depth far beyond the optical transport mean free path (∼1 mm in biological tissues), photoacoustic computed tomography (PACT) offers a promising complementary modality. In this article, PACT for functional human brain imaging is reviewed in its hardware, reconstruction algorithms,
    Language English
    Publishing date 2021-06-15
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2572216-5
    ISSN 2156-7085
    ISSN 2156-7085
    DOI 10.1364/BOE.423707
    Database MEDical Literature Analysis and Retrieval System OnLINE

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